MIF Receptor CD74 is Restricted to Microglia/Macrophages, Associated with a M1-Polarized Immune Milieu and Prolonged Patient Survival in Gliomas

Brain Pathology

Volumn 25, Issue 4, 2015, Pages 491-504

  Zeiner, Pia S ^a   Preusse, Corinna ^a   Blank, Anna Eva ^a   Zachskorn, Cornelia ^a   Baumgarten, Peter ^a,d   Caspary, Lixi ^a   Braczynski, Anne K ^a   Weissenberger, Jakob ^a   Bratzke, Hansjürgen ^b   Reiß, Sandy ^c   Pennartz, Sandra ^c   Winkelmann, Ria ^c   Senft, Christian ^a,d   Plate, Karl H ^a   Wischhusen, Jörg ^e   Stenzel, Werner ^a   Harter, Patrick N ^a   Mittelbronn, Michel ^a  

^a GOETHE UNIVERSITY   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d MILTENYI BIOTEC GMBH   (Germany)

^e UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

CD74; glioma; immune polarization; MIF

Indexed keywords

COLONY STIMULATING FACTOR 1; CYTOKINE RECEPTOR; MACROPHAGE MIGRATION INHIBITION FACTOR; PROTEIN CD74; UNCLASSIFIED DRUG; AIF1 PROTEIN, HUMAN; CD47 ANTIGEN; DNA BINDING PROTEIN; GLIAL FIBRILLARY ACIDIC PROTEIN; MESSENGER RNA;

ARTICLE; BRAIN TISSUE; CANCER PROGNOSIS; CANCER SURVIVAL; CANCER TISSUE; CELL FRACTIONATION; CELL SELECTION; CONTROLLED STUDY; GENE EXPRESSION; GLIOMA; GLIOMA ASSOCIATED MACROPHAGE; GLIOMA ASSOCIATED MICROGLIA; GLIOMA CELL; GLIOMA CELL LINE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MACROPHAGE; MICROGLIA; POLARIZATION; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; BRAIN TUMOR; FEMALE; FLOW CYTOMETRY; GENETICS; KAPLAN MEIER METHOD; MALE; METABOLISM; MICROARRAY ANALYSIS; MORTALITY; PATHOLOGY; PHYSIOLOGY; TUMOR CELL LINE; UPREGULATION;

ANTIGENS, CD47; BRAIN NEOPLASMS; CELL LINE, TUMOR; DNA-BINDING PROTEINS; FEMALE; FLOW CYTOMETRY; GLIAL FIBRILLARY ACIDIC PROTEIN; GLIOMA; HUMANS; KAPLAN-MEIER ESTIMATE; MACROPHAGES; MALE; MICROARRAY ANALYSIS; MICROGLIA; RNA, MESSENGER; UP-REGULATION;

EID: 84931467206     PISSN: 10156305     EISSN: 17503639     Source Type: Journal    
DOI: 10.1111/bpa.12194     Document Type: Article

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