A Uniform Management Approach to Optimize Outcome in Fetal Growth Restriction

Obstetrics and Gynecology Clinics of North America

Volumn 42, Issue 2, 2015, Pages 275-288

  Seravalli, Viola ^a   Baschat, Ahmet A ^a  

^a JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Biophysical profile score; Fetal acidemia; Fetal Doppler; Fetal growth restriction; Fetal testing; Middle cerebral artery; Neonatal outcome; Umbilical artery

Indexed keywords

ACID BASE BALANCE; ACIDEMIA; DETERIORATION; DISEASE ASSOCIATION; FETUS MONITORING; FETUS WEIGHT; GESTATIONAL AGE; HUMAN; INTRAUTERINE GROWTH RETARDATION; MIDDLE CEREBRAL ARTERY; OUTCOME ASSESSMENT; PHENOTYPE; PRIORITY JOURNAL; QUALITY OF LIFE; REVIEW; RISK ASSESSMENT; STILLBIRTH; SURVIVAL RATE; TREATMENT PLANNING; ADULT; DOPPLER FLOWMETRY; ECHOGRAPHY; EMBRYOLOGY; FEMALE; FETUS; FETUS ECHOGRAPHY; PATHOPHYSIOLOGY; PHYSIOLOGY; PLACENTA INSUFFICIENCY; PRACTICE GUIDELINE; PREGNANCY; PROCEDURES; UMBILICAL ARTERY; VASCULARIZATION;

ADULT; FEMALE; FETAL GROWTH RETARDATION; FETAL MONITORING; FETUS; GESTATIONAL AGE; HUMANS; MIDDLE CEREBRAL ARTERY; PLACENTAL INSUFFICIENCY; PRACTICE GUIDELINES AS TOPIC; PREGNANCY; STILLBIRTH; ULTRASONOGRAPHY, DOPPLER; ULTRASONOGRAPHY, PRENATAL; UMBILICAL ARTERIES;

EID: 84931451611     PISSN: 08898545     EISSN: 15580474     Source Type: Journal    
DOI: 10.1016/j.ogc.2015.01.005     Document Type: Review

References (64)

1. Divon M.Y., Girz B.A., Lieblich R., et al. Clinical management of the fetus with markedly diminished umbilical artery end-diastolic flow. Am J Obstet Gynecol 1989, 161(6 Pt 1):1523-1527.
2. Boers K.E., Vijgen S.M., Bijlenga D., et al. Induction versus expectant monitoring for intrauterine growth restriction at term: randomised equivalence trial (DIGITAT). BMJ 2010, 341:c7087.
3. Lees C., Marlow N., Arabin B., et al. Perinatal morbidity and mortality in early-onset fetal growth restriction: cohort outcomes of the trial of randomized umbilical and fetal flow in Europe (TRUFFLE). Ultrasound Obstet Gynecol 2013, 42(4):400-408.
4. Thornton J.G., Hornbuckle J., Vail A., et al. Infant wellbeing at 2 years of age in the Growth Restriction Intervention Trial (GRIT): multicentred randomised controlled trial. Lancet 2004, 364(9433):513-520.
5. Baschat A.A., Cosmi E., Bilardo C.M., et al. Predictors of neonatal outcome in early-onset placental dysfunction. Obstet Gynecol 2007, 109(2 Pt 1):253-261.
6. Baschat A.A. Fetal responses to placental insufficiency: an update. BJOG 2004, 111(10):1031-1041.
7. Meekins J.W., Pijnenborg R., Hanssens M., et al. Astudy of placental bed spiral arteries and trophoblast invasion in normal and severe pre-eclamptic pregnancies. Br J Obstet Gynaecol 1994, 101(8):669-674.
8. Morrow R.J., Adamson S.L., Bull S.B., et al. Effect of placental embolization on the umbilical arterial velocity waveform in fetal sheep. Am J Obstet Gynecol 1989, 161(4):1055-1060.
9. Arbeille P., Maulik D., Fignon A., et al. Assessment of the fetal PO2 changes by cerebral and umbilical Doppler on lamb fetuses during acute hypoxia. Ultrasound Med Biol 1995, 21(7):861-870.
10. Picklesimer A.H., Oepkes D., Moise K.J., et al. Determinants of the middle cerebral artery peak systolic velocity in the human fetus. Am J Obstet Gynecol 2007, 197(5):526.e1-526.e4.
11. Baschat A.A., Weiner C.P. Umbilical artery doppler screening for detection of the small fetus in need of antepartum surveillance. Am J Obstet Gynecol 2000, 182(1 Pt 1):154-158.
12. Bahado-Singh R.O., Kovanci E., Jeffres A., et al. The Doppler cerebroplacental ratio and perinatal outcome in intrauterine growth restriction. Am J Obstet Gynecol 1999, 180(3 Pt 1):750-756.
13. Seravalli V., Block-Abraham D.M., Turan O.M., et al. Second-trimester prediction of delivery of a small-for-gestational-age neonate: integrating sequential Doppler information, fetal biometry, and maternal characteristics. Prenat Diagn 2014, 34(11):1037-1043.
14. Unterscheider J., Daly S., Geary M.P., et al. Optimizing the definition of intrauterine growth restriction: the multicenter prospective PORTO Study. Am J Obstet Gynecol 2013, 208(4):290.e1-290.e6.
15. Parra-Saavedra M., Crovetto F., Triunfo S., et al. Association of Doppler parameters with placental signs of underperfusion in late-onset small-for-gestational-age pregnancies. Ultrasound Obstet Gynecol 2014, 44(3):330-337.
16. Oros D., Figueras F., Cruz-Martinez R., et al. Longitudinal changes in uterine, umbilical and fetal cerebral Doppler indices in late-onset small-for-gestational age fetuses. Ultrasound Obstet Gynecol 2011, 37(2):191-195.
17. Kovo M., Schreiber L., Ben-Haroush A., et al. The placental component in early-onset and late-onset preeclampsia in relation to fetal growth restriction. Prenat Diagn 2012, 32(7):632-637.
18. Ogge G., Chaiworapongsa T., Romero R., et al. Placental lesions associated with maternal underperfusion are more frequent in early-onset than in late-onset preeclampsia. JPerinat Med 2011, 39(6):641-652.
19. Egbor M., Ansari T., Morris N., et al. Morphometric placental villous and vascular abnormalities in early- and late-onset pre-eclampsia with and without fetal growth restriction. BJOG 2006, 113(5):580-589.
20. Matsuo K., Malinow A.M., Harman C.R., et al. Decreased placental oxygenation capacity in pre-eclampsia: clinical application of a novel index of placental function preformed at the time of delivery. JPerinat Med 2009, 37(6):657-661.
21. Parra-Saavedra M., Simeone S., Triunfo S., et al. Correlation between histological signs of placental underperfusion and perinatal morbidity in late-onset small for gestational age fetuses. Ultrasound Obstet Gynecol 2015, 45(2):149-155.
22. Savchev S., Figueras F., Sanz-Cortes M., et al. Evaluation of an optimal gestational age cut-off for the definition of early- and late-onset fetal growth restriction. Fetal Diagn Ther 2014, 36(2):99-105.
23. Unterscheider J., Daly S., Geary M.P., et al. Predictable progressive Doppler deterioration in IUGR: does it really exist?. Am J Obstet Gynecol 2013, 209(6):539.e1-539.e7.
24. Hershkovitz R., Kingdom J.C., Geary M., et al. Fetal cerebral blood flow redistribution in late gestation: identification of compromise in small fetuses with normal umbilical artery Doppler. Ultrasound Obstet Gynecol 2000, 15(3):209-212.
25. Frøen J.F., Gardosi J.O., Thurmann A., et al. Restricted fetal growth in sudden intrauterine unexplained death. Acta Obstet Gynecol Scand 2004, 83(9):801-807.
26. Winje B.A., Roald B., Kristensen N.P., et al. Placental pathology in pregnancies with maternally perceived decreased fetal movement-a population-based nested case-cohort study. PLoS One 2012, 7(6):e39259.
27. Divon M.Y., Chamberlain P.F., Sipos L., et al. Identification of the small for gestational age fetus with the use of gestational age-independent indices of fetal growth. Am J Obstet Gynecol 1986, 155(6):1197-1201.
28. Bilardo C.M., Nicolaides K.H., Campbell S. Doppler measurements of fetal and uteroplacental circulations: relationship with umbilical venous blood gases measured at cordocentesis. Am J Obstet Gynecol 1990, 162(1):115-120.
29. Akalin-Sel T., Nicolaides K.H., Peacock J., et al. Doppler dynamics and their complex interrelation with fetal oxygen pressure, carbon dioxide pressure, and pH in growth-retarded fetuses. Obstet Gynecol 1994, 84(3):439-444.
30. Hecher K., Snijders R., Campbell S., et al. Fetal venous, intracardiac, and arterial blood flow measurements in intrauterine growth retardation: relationship with fetal blood gases. Am J Obstet Gynecol 1995, 173(1):10-15.
31. Rizzo G., Capponi A., Arduini D., et al. The value of fetal arterial, cardiac and venous flows in predicting pH and blood gases measured in umbilical blood at cordocentesis in growth retarded fetuses. Br J Obstet Gynaecol 1995, 102(12):963-969.
32. Baschat A.A., Güclü S., Kush M.L., et al. Venous Doppler in the prediction of acid-base status of growth-restricted fetuses with elevated placental blood flow resistance. Am J Obstet Gynecol 2004, 191(1):277-284.
33. Cruz-Martínez R., Figueras F., Hernandez-Andrade E., et al. Fetal brain Doppler to predict cesarean delivery for nonreassuring fetal status in term small-for-gestational-age fetuses. Obstet Gynecol 2011, 117(3):618-626.
34. Severi F.M., Bocchi C., Visentin A., et al. Uterine and fetal cerebral Doppler predict the outcome of third-trimester small-for-gestational age fetuses with normal umbilical artery Doppler. Ultrasound Obstet Gynecol 2002, 19(3):225-228.
35. Ribbert L.S., Snijders R.J., Nicolaides K.H., et al. Relationship of fetal biophysical profile and blood gas values at cordocentesis in severely growth-retarded fetuses. Am J Obstet Gynecol 1990, 163(2):569-571.
36. Manning F.A., Snijders R., Harman C.R., et al. Fetal biophysical profile score. VI. Correlation with antepartum umbilical venous fetal pH. Am J Obstet Gynecol 1993, 169(4):755-763.
37. Baschat A.A. Integrated fetal testing in growth restriction: combining multivessel Doppler and biophysical parameters. Ultrasound Obstet Gynecol 2003, 21(1):1-8.
38. Baschat A.A., Gembruch U., Harman C.R. The sequence of changes in Doppler and biophysical parameters as severe fetal growth restriction worsens. Ultrasound Obstet Gynecol 2001, 18(6):571-577.
39. Ribbert L.S., Snijders R.J., Nicolaides K.H., et al. Relation of fetal blood gases and data from computer-assisted analysis of fetal heart rate patterns in small for gestation fetuses. Br J Obstet Gynaecol 1991, 98(8):820-823.
40. Vintzileos A.M., Fleming A.D., Scorza W.E., et al. Relationship between fetal biophysical activities and umbilical cord blood gas values. Am J Obstet Gynecol 1991, 165(3):707-713.
41. Guzman E., Vintzileos A., Martins M., et al. The efficacy of individual computer heart rate indices in detecting acidemia at birth in growth-restricted fetuses. Obstet Gynecol 1996, 87(6):969-974.
42. Turan S., Turan O.M., Berg C., et al. Computerized fetal heart rate analysis, Doppler ultrasound and biophysical profile score in the prediction of acid-base status of growth-restricted fetuses. Ultrasound Obstet Gynecol 2007, 30(5):750-756.
43. Odibo A.O., Goetzinger K.R., Cahill A.G., et al. Combined sonographic testing index and prediction of adverse outcome in preterm fetal growth restriction. Am J Perinatol 2014, 31(2):139-144.
44. Turan S., Miller J., Baschat A.A. Integrated testing and management in fetal growth restriction. Semin Perinatol 2008, 32(3):194-200.
45. Arduini D., Rizzo G., Romanini C. Changes of pulsatility index from fetal vessels preceding the onset of late decelerations in growth-retarded fetuses. Obstet Gynecol 1992, 79(4):605-610.
46. Harrington K., Thompson M.O., Carpenter R.G., et al. Doppler fetal circulation in pregnancies complicated by pre-eclampsia or delivery of a small for gestational age baby: 2. Longitudinal analysis. Br J Obstet Gynaecol 1999, 106(5):453-466.
47. Hecher K., Bilardo C.M., Stigter R.H., et al. Monitoring of fetuses with intrauterine growth restriction: a longitudinal study. Ultrasound Obstet Gynecol 2001, 18(6):564-570.
48. Senat M.V., Schwärzler P., Alcais A., et al. Longitudinal changes in the ductus venosus, cerebral transverse sinus and cardiotocogram in fetal growth restriction. Ultrasound Obstet Gynecol 2000, 16(1):19-24.
49. Visser G.H., Bekedam D.J., Ribbert L.S. Changes in antepartum heart rate patterns with progressive deterioration of the fetal condition. Int J Biomed Comput 1990, 25(4):239-246.
50. Ferrazzi E., Bozzo M., Rigano S., et al. Temporal sequence of abnormal Doppler changes in the peripheral and central circulatory systems of the severely growth-restricted fetus. Ultrasound Obstet Gynecol 2002, 19(2):140-146.
51. Turan O.M., Turan S., Gungor S., et al. Progression of Doppler abnormalities in intrauterine growth restriction. Ultrasound Obstet Gynecol 2008, 32(2):160-167.
52. Cosmi E., Ambrosini G., D'Antona D., et al. Doppler, cardiotocography, and biophysical profile changes in growth-restricted fetuses. Obstet Gynecol 2005, 106(6):1240-1245.
53. Baschat A.A., Kush M., Berg C., et al. Hematologic profile of neonates with growth restriction is associated with rate and degree of prenatal Doppler deterioration. Ultrasound Obstet Gynecol 2013, 41(1):66-72.
54. Turan O.M., Turan S., Berg C., et al. Duration of persistent abnormal ductus venosus flow and its impact on perinatal outcome in fetal growth restriction. Ultrasound Obstet Gynecol 2011, 38(3):295-302.
55. Hernandez-Andrade E., Stampalija T., Figueras F. Cerebral blood flow studies in the diagnosis and management of intrauterine growth restriction. Curr Opin Obstet Gynecol 2013, 25(2):138-144.
56. Crimmins S., Desai A., Block-Abraham D., et al. Acomparison of Doppler and biophysical findings between liveborn and stillborn growth-restricted fetuses. Am J Obstet Gynecol 2014, 211(6):669.e1-669.e10.
57. Visser G.H., Bilardo C.M., Lees C. Fetal growth restriction at the limits of viability. Fetal Diagn Ther 2014, 36(2):162-165.
58. Baschat A.A. Neurodevelopment following fetal growth restriction and its relationship with antepartum parameters of placental dysfunction. Ultrasound Obstet Gynecol 2011, 37(5):501-514.
59. Arcangeli T., Thilaganathan B., Hooper R., et al. Neurodevelopmental delay in small babies at term: a systematic review. Ultrasound Obstet Gynecol 2012, 40(3):267-275.
60. Sotiriadis A, Tsiami A, Papatheodorou S, etal. Neurodevelopmental outcome after a single course of antenatal steroids in preterm infants: a systematic review and meta-analysis. Obs Gynecol, in press.
61. Royal College of Obstetricians and Gynaecologists (RCOG). The investigation and management of the small-for-gestational-age fetus. Green-top Guideline No. 31. 2nd edition. 2013. Available at:. https://www.rcog.org.uk/en/guidelines-research-services/guidelines/gtg31/.
62. New Zealand Maternal Fetal Medicine Network. Guideline for the management of suspected small for gestational age singleton pregnancies after 34 weeks gestation. 2013. Available at:. http://www.asum.com.au/newsite/Files/Documents/Resources/NZMFM%20SGA%20Guideline_September%202013.pdf.
63. Boers K.E., van Wyk L., van der Post J.A., et al. Neonatal morbidity after induction vs expectant monitoring in intrauterine growth restriction at term: a subanalysis of the DIGITAT RCT. Am J Obstet Gynecol 2012, 206(4):344.e1-344.e7.
64. Trudell A.S., Cahill A.G., Tuuli M.G., et al. Risk of stillbirth after 37 weeks in pregnancies complicated by small-for-gestational-age fetuses. Am J Obstet Gynecol 2013, 208(5):376.e1-376.e7.