Interleukin-18 enhances breast cancer cell migration via down-regulation of claudin-12 and induction of the p38 MAPK pathway

Biochemical and Biophysical Research Communications

Volumn 459, Issue 3, 2015, Pages 379-386

  Yang, Yoolhee ^a   Cheon, Soyoung ^b   Jung, Min Kyung ^b   Song, Seok Bean ^b   Kim, Daejin ^c   Kim, Hee Jung ^d   Park, Hyunjeong ^d   Bang, Sa Ik ^a   Cho, Daeho ^b  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Sookmyung Women's University   (South Korea)

^c Chung Ang University   (South Korea)

^d The Catholic University of Korea   (South Korea)

Author keywords

Breast cancer; Claudin 12; Interleukin 18 (IL 18); Migration; Tight junction

Indexed keywords

2-(2-AMINO-3-METHOXYPHENYL)-4H-1-BENZOPYRAN-4-ONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; CLAUDIN; CLAUDIN 1; CLAUDIN 3; CLAUDIN 4; CLDN1 PROTEIN, HUMAN; CLDN12 PROTEIN, HUMAN; CLDN3 PROTEIN, HUMAN; CLDN4 PROTEIN, HUMAN; FLAVONOID; IMIDAZOLE DERIVATIVE; INTERLEUKIN 18; PROTEIN KINASE INHIBITOR; PYRIDINE DERIVATIVE; RECOMBINANT PROTEIN; SMALL INTERFERING RNA;

ANTAGONISTS AND INHIBITORS; BREAST TUMOR; CELL MOTION; DOWN REGULATION; DRUG EFFECTS; FEMALE; GENE SILENCING; GENETICS; HUMAN; MCF 7 CELL LINE; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; TIGHT JUNCTION; TUMOR CELL LINE;

BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CLAUDIN-1; CLAUDIN-3; CLAUDIN-4; CLAUDINS; DOWN-REGULATION; FEMALE; FLAVONOIDS; GENE KNOCKDOWN TECHNIQUES; HUMANS; IMIDAZOLES; INTERLEUKIN-18; MAP KINASE SIGNALING SYSTEM; MCF-7 CELLS; PROTEIN KINASE INHIBITORS; PYRIDINES; RECOMBINANT PROTEINS; RNA, SMALL INTERFERING; TIGHT JUNCTIONS;

EID: 84931372818     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.02.108     Document Type: Article

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