The impact of acid-suppressing drugs to the patients with chronic obstructive pulmonary disease: A nationwide, population-based, cohort study

Journal of Research in Medical Sciences

Volumn 20, Issue 3, 2015, Pages 263-267

  Lee, Shou Wu ^a,b   Lien, Han Chung ^a,c   Chang, Chi Sen ^a,b   Yeh, Hong Zen ^a,c   Lee, Teng Yu ^a,c   Tung, Chun Fang ^a  

^a TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c NATIONAL YANG MING UNIVERSITY   (Taiwan)

Author keywords

Chronic obstructive pulmonary disease; Histamine receptor 2 antagonists; Pneumonia; Proton pump inhibitors

Indexed keywords

GLUCOCORTICOID; HISTAMINE H2 RECEPTOR ANTAGONIST; PROTON PUMP INHIBITOR;

ADULT; AGED; ARTICLE; CHRONIC OBSTRUCTIVE LUNG DISEASE; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MORTALITY; PNEUMONIA; TREATMENT OUTCOME;

EID: 84931294973     PISSN: 17351995     EISSN: 17357136     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Pauwels RA, Rabe KF. Burden and clinical features of chronic obstructive pulmonary disease (COPD). Lancet 2004;364:613-20.
2. Casanova C, Baudet JS, del Valle Velasco M, Martin JM, Aguirre Jaime A, de Torres JP, et al. Increased gastro-oesophageal reflux disease in patients with severe COPD. Eur Respir J 2004;23:841-5.
3. Mokhlesi B, Morris AL, Huang CF, Curcio AJ, Barrett TA, Kamp DW. Increased prevalence of gastroesophageal reflux symptoms in patients with COPD. Chest 2001;119:1043-8.
4. Sasaki T, Nakayama K, Yasuda H, Yamaya M. A new strategy with proton pump inhibitors for the prevention of acute exacerbations in COPD. Ther Adv Respir Dis 2011;5:91-103.
5. Laheij RJ, Van Ijzendoorn MC, Janssen MJ, Jansen JB. Gastric acid-suppressive therapy and community-acquired respiratory infections. Aliment Pharmacol Ther 2003;18:847-51.
6. Laheij RJ, Sturkenboom MC, Hassing RJ, Dieleman J, Stricker BH, Jansen JB. Risk of community-acquired pneumonia and use of gastric acid-suppressive drugs. JAMA 2004;292:1955-60.
7. Gulmez SE, Holm A, Frederiksen H, Jensen TG, Pedersen C, Hallas J. Use of proton pump inhibitors and the risk of communityacquired pneumonia: A population-based case-control study. Arch Intern Med 2007;167:950-5.
8. Sarkar M, Hennessy S, Yang YX. Proton-pump inhibitor use and the risk for community-acquired pneumonia. Ann Intern Med 2008;149:391-8.
9. Zielinski J, MacNee W, Wedzicha J, Ambrosino N, Braghiroli A, Dolensky J, et al. Causes of death in patients with COPD and chronic respiratory failure. Monaldi Arch Chest Dis 1997;52:43-7.
10. Kempainen RR, Savik K, Whelan TP, Dunitz JM, Herrington CS, Billings JL. High prevalence of proximal and distal gastroesophageal reflux disease in advanced COPD. Chest 2007;131:1666-71.
11. Johnstone J, Nerenberg K, Loeb M. Meta-analysis: Proton pump inhibitor use and the risk of community-acquired pneumonia. Aliment Pharmacol Ther 2010;31:1165-77.
12. Torres A, El-Ebiary M, Soler N, Montón C, Fàbregas N, Hernández C. Stomach as a source of colonization of the respiratory tract during mechanical ventilation: Association with ventilator-associated pneumonia. Eur Respir J 1996;9:1729-35.
13. Williams C, McColl KE. Review article: Proton pump inhibitors and bacterial overgrowth. Aliment Pharmacol Ther 2006;23:3-10.
14. Altman KW, Haines GK 3, Hammer ND, Radosevich JA. The H+/K+-ATPase (proton) pump is expressed in human laryngeal submucosal glands. Laryngoscope 2003;113:1927-30.
15. Altman KW, Waltonen JD, Tarjan G, Radosevich JA, Haines GK 3. Human lung mucous glands manifest evidence of the H+/K+ATPase proton pump. Ann Otol Rhinol Laryngol 2007;116:229-34.
16. Eom CS, Jeon CY, Lim JW, Cho EG, Park SM, Lee KS. Use of acid-suppressive drugs and risk of pneumonia: A systematic review and meta-analysis. CMAJ 2011;183:310-9.
17. Giuliano C, Wilhelm SM, Kale-Pradhan PB. Are proton pump inhibitors associated with the development of community-acquired pneumonia? A meta-analysis. Expert Rev Clin Pharmacol 2012;5:337-44.
18. Dublin S, Walker RL, Jackson ML, Nelson JC, Weiss NS, Jackson LA. Use of proton pump inhibitors and H2 blockers and risk of pneumonia in older adults: A population-based case-control study. Pharmacoepidemiol Drug Saf 2010;19:792-802.