Phosphatase and tensin homolog (PTEN) represses colon cancer progression through inhibiting paxillin transcription via PI3K/AKT/NF-κB pathway

Journal of Biological Chemistry

Volumn 290, Issue 24, 2015, Pages 15018-15029

  Zhang, Ling Li ^a,b   Mu, Gang Gang ^a   Ding, Qian Shan ^a   Li, Yan Xia ^a   Shi, Yun Bo ^b   Dai, Jin Fen ^a   Yu, Hong Gang ^a  

^a RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF ZHENGZHOU UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING SITES; PHOSPHATASES; TRANSCRIPTION; TUMORS;

COLON CANCER CELLS; HUMAN COLON CANCER; OVER-EXPRESSION; SIGNALING CASCADES; THERAPEUTIC TARGETS; TRANSCRIPTIONAL TARGETS; TUMOR FORMATION; TUMOR SUPPRESSOR GENES;

DISEASES;

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; PAXILLIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; DNA; PRIMER DNA; PTEN PROTEIN, MOUSE; PXN PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING SITE; CANCER CELL LINE; CANCER GROWTH; CANCER INHIBITION; CELL INVASION; CELL MIGRATION; CLINICAL ARTICLE; COLON CANCER; CONTROLLED STUDY; ENZYME REPRESSION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN INTERACTION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; ANIMAL; CHROMATIN IMMUNOPRECIPITATION; COLON TUMOR; DISEASE COURSE; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; NUCLEOTIDE SEQUENCE; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; PROMOTER REGION; REAL TIME POLYMERASE CHAIN REACTION;

MUS MUSCULUS;

ANIMALS; BASE SEQUENCE; CHROMATIN IMMUNOPRECIPITATION; COLONIC NEOPLASMS; DISEASE PROGRESSION; DNA; DNA PRIMERS; HUMANS; MICE; MICE, NUDE; NF-KAPPA B; PAXILLIN; PHOSPHATIDYLINOSITOL 3-KINASES; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; REAL-TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION, GENETIC;

EID: 84931281491     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.641407     Document Type: Article

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