Increased prevalence of carbapenem resistant Enterobacteriaceae in hospital setting due to cross-species transmission of the blaNDM-1 element and clonal spread of progenitor resistant strains

Frontiers in Microbiology

Volumn 6, Issue MAY, 2015, Pages

  Wang, Xuan ^a   Chen, Gongxiang ^a   Wu, Xiaoyan ^b   Wang, Liangping ^c   Cai, Jiachang ^a   Chan, Edward Waichi ^d   Chen, Sheng ^d   Zhang, Rong ^a  

^a THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Second People's Hospital of Jiaxing   (China)

^c People's Hospital of Pinghu   (China)

^d HONG KONG POLYTECHNIC UNIVERSITY   (Hong Kong)

Author keywords

Carbapenem resistant Enterobacteriaceae; Clonal spread; Mobile element; NDM 1

Indexed keywords

AMIKACIN; AMOXICILLIN PLUS CLAVULANIC ACID; AZTREONAM; CARBAPENEM; CEFOTAXIME; CEFTAZIDIME; FOSFOMYCIN; IMIPENEM; INOSINE PHOSPHATE; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM; TIGECYCLINE;

AGAR DILUTION; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIAL TRANSMISSION; BACTERIUM CONJUGATION; CARBAPENEM RESISTANT ENTEROBACTERIACEAE; CHINA; CITROBACTER FREUNDII; ENTEROBACTER CLOACAE; ESCHERICHIA COLI; GENETIC ANALYSIS; INFECTION CONTROL; KLEBSIELLA OXYTOCA; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; MORGANELLA MORGANII; MULTILOCUS SEQUENCE TYPING; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PREVALENCE; PULSED FIELD GEL ELECTROPHORESIS;

CITROBACTER FREUNDII; ENTEROBACTER CLOACAE; ENTEROBACTERIACEAE; ESCHERICHIA COLI; KLEBSIELLA OXYTOCA; KLEBSIELLA PNEUMONIAE; MORGANELLA MORGANII;

EID: 84931269139     PISSN: None     EISSN: 1664302X     Source Type: Journal    
DOI: 10.3389/fmicb.2015.00595     Document Type: Article

References (31)

1. Dalhoff A, and Thomson CJ. The art of fusion: from penams and cephems to penems. Chemotherapy. 2003;49(3):105-20.
2. Zilberberg MD, and Shorr AF. Secular trends in gram-negative resistance among urinary tract infection hospitalizations in the United States, 2000-2009. Infect Control Hosp Epidemiol. 2013;34(9):940-6.
3. Goel N, Wattal C, Oberoi JK, Raveendran R, Datta S, and Prasad KJ. Trend analysis of antimicrobial consumption and development of resistance in non-fermenters in a tertiary care hospital in Delhi, India. J Antimicrob Chemother. 2011;66(7):1625-30.
4. Karaiskos I, and Giamarellou H. Multidrug-resistant and extensively drug-resistant Gram-negative pathogens: current and emerging therapeutic approaches. Expert Opin Pharmacother. 2014;15(10):1351-70.
5. Livermore DM. Has the era of untreatable infections arrived? J Antimicrob Chemother. 2009;64 Suppl 1:i29-36.
6. Livermore DM. The need for new antibiotics. Clin Microbiol Infect. 2004;10 Suppl 4:1-9.
7. Stock I. [Infectious diseases caused by carbapenemase-producing Enterobacteriaceae-a particular challenge for antibacterial therapy]. Medizinische Monatsschrift fur Pharmazeuten. 2014;37(5):162-72; quiz 73-4.
8. Nordmann P, Naas T, and Poirel L. Global spread of Carbapenemase-producing Enterobacteriaceae. Emerging infectious diseases. 2011;17(10):1791-8.
9. Yong D, Toleman MA, Giske CG, Cho HS, Sundman K, Lee K, and Walsh TR. Characterization of a new metallo-beta-lactamase gene, bla(NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. Antimicrobial agents and chemotherapy. 2009;53(12):5046-54.
10. Chen Y, Zhou Z, Jiang Y, and Yu Y. Emergence of NDM-1-producing Acinetobacter baumannii in China. The Journal of antimicrobial chemotherapy. 2011;66(6):1255-9.
11. Berrazeg M, Diene S, Medjahed L, Parola P, Drissi M, Raoult D, and Rolain J. New Delhi Metallo-beta-lactamase around the world: an eReview using Google Maps. Euro surveillance: bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin. 2014;19(20).
12. Qin S, Fu Y, Zhang Q, Qi H, Wen JG, Xu H, Xu L, Zeng L, Tian H, Rong L, et al. High incidence and endemic spread of NDM-1-positive Enterobacteriaceae in Henan Province, China. Antimicrobial agents and chemotherapy. 2014;58(8):4275-82.
13. Hu L, Zhong Q, Shang Y, Wang H, Ning C, Li Y, Hang Y, Xiong J, Wang X, Xu Y, et al. The prevalence of carbapenemase genes and plasmid-mediated quinolone resistance determinants in carbapenem-resistant Enterobacteriaceae from five teaching hospitals in central China. Epidemiology and infection. 2014;142(9):1972-7.
14. Zhou S, Chen X, Meng X, Zhang G, Wang J, Zhou D, and Guo X. "Roar" of blaNDM-1 and "silence" of blaOXA-58 co-exist in Acinetobacter pittii. Scientific reports. 2015;5:8976.
15. Dallenne C, Da Costa A, Decre D, Favier C, and Arlet G. Development of a set of multiplex PCR assays for the detection of genes encoding important beta-lactamases in Enterobacteriaceae. The Journal of antimicrobial chemotherapy. 2010;65(3):490-5.
16. Borgia S, Lastovetska O, Richardson D, Eshaghi A, Xiong J, Chung C, Baqi M, McGeer A, Ricci G, Sawicki R, et al. Outbreak of carbapenem-resistant enterobacteriaceae containing blaNDM-1, Ontario, Canada. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America. 2012;55(11):e109-17.
17. Patel G, and Bonomo RA. "Stormy waters ahead": global emergence of carbapenemases. Frontiers in microbiology. 2013;4:48.
18. Wang X, Liu W, Zou D, Li X, Wei X, Shang W, Wang Y, Li H, Huan Li YW, He X, et al. High rate of New Delhi metallo-beta-lactamase 1-producing bacterial infection in China. Clinical infectious diseases: an official publication of the Infectious Diseases Society of America. 2013;56(1):161-2.
19. Zhou G, Guo S, Luo Y, Ye L, Song Y, Sun G, Guo L, Chen Y, Han L, and Yang J. NDM-1-producing strains, family Enterobacteriaceae, in hospital, Beijing, China. Emerging infectious diseases. 2014;20(2):340-2.
20. Poirel L, Dortet L, Bernabeu S, and Nordmann P. Genetic features of blaNDM-1-positive Enterobacteriaceae. Antimicrobial agents and chemotherapy. 2011;55(11):5403-7.
21. Cuzon G, Bonnin RA, and Nordmann P. First identification of novel NDM carbapenemase, NDM-7, in Escherichia coli in France. PloS one. 2013;8(4):e61322.
22. Yang Z, Liu W, Cui Q, Niu W, Li H, Zhao X, Wei X, Wang X, Huang S, Dong D, et al. Prevalence and detection of Stenotrophomonas maltophilia carrying metallo-beta-lactamase blaL1 in Beijing, China. Frontiers in microbiology. 2014;5:692.
23. Zhang X, Lou D, Xu Y, Shang Y, Li D, Huang X, Li Y, Hu L, Wang L, and Yu F. First identification of coexistence of blaNDM-1 and blaCMY-42 among Escherichia coli ST167 clinical isolates. BMC microbiology. 2013;13:282.
24. Giske CG, Froding I, Hasan CM, Turlej-Rogacka A, Toleman M, Livermore D, Woodford N, and Walsh TR. Diverse sequence types of Klebsiella pneumoniae contribute to the dissemination of blaNDM-1 in India, Sweden, and the United Kingdom. Antimicrobial agents and chemotherapy. 2012;56(5):2735-8.
25. Peirano G, Ahmed-Bentley J, Fuller J, Rubin JE, and Pitout JD. Travel-related carbapenemase-producing Gram-negative bacteria in Alberta, Canada: the first 3 years. Journal of clinical microbiology. 2014;52(5):1575-81.
26. Majewski P, Wieczorek P, Sacha PT, Frank M, Juszczyk G, Ojdana D, Klosowska W, Wieczorek A, Sienko A, Michalska AD, et al. Emergence of OXA-48 carbapenemase-producing Enterobacter cloacae ST89 infection in Poland. International journal of infectious diseases: IJID: official publication of the International Society for Infectious Diseases. 2014;25:107-9.
27. Izdebski R, Baraniak A, Herda M, Fiett J, Bonten MJ, Carmeli Y, Goossens H, Hryniewicz W, Brun-Buisson C, and Gniadkowski M. MLST reveals potentially high-risk international clones of Enterobacter cloacae. The Journal of antimicrobial chemotherapy. 2014.
28. Rozales FP, Ribeiro VB, Magagnin CM, Pagano M, Lutz L, Falci DR, Machado A, Barth AL, and Zavascki AP. Emergence of NDM-1-producing Enterobacteriaceae in Porto Alegre, Brazil. International journal of infectious diseases: IJID: official publication of the International Society for Infectious Diseases. 2014;25:79-81.
29. Stoesser N, Sheppard AE, Shakya M, Sthapit B, Thorson S, Giess A, Kelly D, Pollard AJ, Peto TE, Walker AS, et al. Dynamics of MDR Enterobacter cloacae outbreaks in a neonatal unit in Nepal: insights using wider sampling frames and next-generation sequencing. The Journal of antimicrobial chemotherapy. 2015;70(4):1008-15.
30. Yanik K, Guney AK, Karadag A, and Eroglu C. [NDM-1 cases and outbreaks in Turkey]. Mikrobiyoloji bulteni. 2014;48(4):709-10.
31. Kumarasamy KK, Toleman MA, Walsh TR, Bagaria J, Butt F, Balakrishnan R, Chaudhary U, Doumith M, Giske CG, Irfan S, et al. Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study. The Lancet Infectious diseases. 2010;10(9):597-602.