Travel-related carbapenemase-producing Gram-negative bacteria in Alberta, Canada: The first 3 years

Journal of Clinical Microbiology

Volumn 52, Issue 5, 2014, Pages 1575-1581

  Peirano, Gisele ^a,b   Ahmed Bentley, Jasmine ^d,e   Fuller, Jeff ^d,f   Rubin, Joseph E ^a,b,c   Pitout, Johann D D ^a  

^a UNIVERSITY OF CALGARY   (Canada)

^b UNIVERSITY OF CALGARY   (Canada)

^c UNIVERSITY OF SASKATCHEWAN   (Canada)

^d UNIVERSITY OF ALBERTA   (Canada)

^e DynaLIFE Dx   (Canada)

^f PROVINCIAL LABORATORY FOR PUBLIC HEALTH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; AMOXICILLIN PLUS CLAVULANIC ACID; AZTREONAM; CARBAPENEMASE; CEFOXITIN; CEFTAZIDIME; CEFTRIAXONE; CIPROFLOXACIN; COLISTIN; COTRIMOXAZOLE; ERTAPENEM; GENTAMICIN; IMIPENEM; MEROPENEM; PIPERACILLIN PLUS TAZOBACTAM; TIGECYCLINE; TOBRAMYCIN; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BETA LACTAMASE;

ACINETOBACTER BAUMANNII; ADULT; AGED; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL INFECTION; BACTERIUM ISOLATION; BLANDM 1 GENE; BROTH DILUTION; CANADA; CARBAPENEMASE PRODUCING GRAM NEGATIVE BACTERIUM; CITROBACTER FREUNDII; CLINICAL ARTICLE; DEATH; DISEASE TRANSMISSION; ENTEROBACTER CLOACAE; ESCHERICHIA COLI; FEMALE; GRAM NEGATIVE BACTERIUM; HOSPITAL ADMISSION; HUMAN; HUMAN TISSUE; KLEBSIELLA PNEUMONIAE; MALE; MIDDLE AGED; MULTILOCUS SEQUENCE TYPING; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROVIDENCIA RETTGERI; SEQUENCE ANALYSIS; TRAVEL; URINARY TRACT INFECTION; YOUNG ADULT; DRUG EFFECTS; GENETICS; GRAM-NEGATIVE BACTERIAL INFECTIONS; INDIA; ISOLATION AND PURIFICATION; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; PROCEDURES; VERY ELDERLY;

ADULT; AGED, 80 AND OVER; ALBERTA; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMASES; FEMALE; GRAM-NEGATIVE BACTERIA; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; INDIA; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MULTILOCUS SEQUENCE TYPING; YOUNG ADULT;

EID: 84899545153     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.00162-14     Document Type: Article

References (49)

1. Paterson DL. 2006. Resistance in Gram-negative bacteria: Enterobacteriaceae. Am. J. Infect. Control 34(5 Suppl 1):S20-S28; discussion S64-S73. http://dx.doi.org/10.1016/j.ajic.2006.05.238.
2. Livermore DM, Woodford N. 2006. The β-lactamase threat in Enterobacteriaceae, Pseudomonas and Acinetobacter. Trends Microbiol. 14:413-420. http://dx.doi.org/10.1016/j.tim.2006.07.008.
3. Nordmann P, Naas T, Poirel L. 2011. Global spread of carbapenemaseproducing Enterobacteriaceae. Emerg. Infect. Dis. 17:1791-1798. http://dx.doi.org/10.3201/eid1710.110655.
4. Yong D, Toleman MA, Giske CG, Cho HS, Sundman K, Lee K, Walsh TR. 2009. Characterization of a new metallo-β-lactamase gene, bla (NDM-1), and a novel erythromycin esterase gene carried on a unique genetic structure in Klebsiella pneumoniae sequence type 14 from India. Antimicrob. Agents Chemother. 53:5046-5054. http://dx.doi.org/10.1128/AAC.00774-09.
5. Johnson AP, Woodford N. 2013. Global spread of antibiotic resistance: the example of New Delhi metallo-β-lactamase (NDM)-mediated carbapenem resistance. J. Med. Microbiol. 62:499-513. http://dx.doi.org/10.1099/jmm.0. 052555-0.
6. Poirel L, Dortet L, Bernabeu S, Nordmann P. 2011. Genetic features of blaNDM-1-positive Enterobacteriaceae. Antimicrob. Agents Chemother. 55:5403-5407. http://dx.doi.org/10.1128/AAC.00585-11.
7. Walsh TR, Weeks J, Livermore DM, Toleman MA. 2011. Dissemination of NDM-1 positive bacteria in the New Delhi environment and its implications for human health: an environmental point prevalence study. Lancet Infect. Dis. 11:355-362. http://dx.doi.org/10.1016/S1473-3099 (11) 70059-7.
8. Walther-Rasmussen J, Hoiby N. 2007. Class A carbapenemases. J. Antimicrob. Chemother. 60:470-482. http://dx.doi.org/10.1093/jac/dkm226.
9. Queenan AM, Bush K. 2007. Carbapenemases: the versatile β-lactamases. Clin. Microbiol. Rev. 20:440-458. http://dx.doi.org/10.1128/ CMR.00001-07.
10. Deshpande LM, Rhomberg PR, Sader HS, Jones RN. 2006. Emergence of serine carbapenemases (KPC and SME) among clinical strains of Enterobacteriaceae isolated in the United States Medical Centers: report from the MYSTIC Program (1999-2005). Diagn. Microbiol. Infect. Dis. 56:367-372. http://dx.doi.org/10. 1016/j.diagmicrobio.2006.07.004.
11. Nordmann P, Cuzon G, Naas T. 2009. The real threat of Klebsiella pneumoniae carbapenemase-producing bacteria. Lancet Infect. Dis. 9:228-236. http://dx.doi.org/10.1016/S1473-3099 (09) 70054-4.
12. Health PHSoA. 2013. Carbapenem-resistant organisms. Government of Alberta, Alberta, Canada. http://www.health.alberta.ca/documents/Guidelines- Carbapenem-Resistant-Organisms-2013.pdf.
13. Peirano G, Ahmed-Bentley J, Fuller J, Rubin JE, Pitout J D D. 2013. Abstr. 53rd Intersci. Conf. Antimicrob. Agents Chemother., abstr C2-905.
14. Peirano G, Ahmed-Bentley J, Woodford N, Pitout JD. 2011. New Delhi metallo-β-lactamase from traveler returning to Canada. Emerg. Infect. Dis. 17:240-242. http://dx.doi.org/10.3201/eid1702.101313.
15. Ahmed-Bentley J, Chandran AU, Joffe AM, French D, Peirano G, Pitout JD. 2013. Gram-negative bacteria that produce carbapenemases causing death attributed to recent foreign hospitalization. Antimicrob. Agents Chemother. 57:3085-3091. http://dx.doi.org/10.1128/AAC.00297-13.
16. Peirano G, Pillai DR, Pitondo-Silva A, Richardson D, Pitout JD. 2011. The characteristics of NDM-producing Klebsiella pneumoniae from Canada. Diagn. Microbiol. Infect. Dis. 71:106-109. http://dx.doi.org/10.1016/j.diagmicrobio. 2011.06.013.
17. Chan WW, Peirano G, Smyth DJ, Pitout JD. 2013. The characteristics of Klebsiella pneumoniae that produce KPC-2 imported from Greece. Diagn. Microbiol. Infect. Dis. 75:317-319. http://dx.doi.org/10.1016/j.diagmicro bio.2012.12.003.
18. Centers for Disease Control and Prevention. 2012. CRE toolkit-guidance for the control of carbapenem-resistant Enterobacteriaceae (CRE). Centers for Disease Control and Prevention, Atlanta, GA. http://www.cdc.gov/hai/organisms/ cre/cre-toolkit/.
19. Clinical and Laboratory Standards Institute. 2012. Performance standards for antimicrobial susceptibility testing: 22nd informational supplement. CLSA document M100-S22. Clinical and Laboratory Standards Institute, Wayne, PA.
20. Doyle D, Peirano G, Lascols C, Lloyd T, Church DL, Pitout JD. 2012. Laboratory detection of Enterobacteriaceae that produce carbapenemases. J. Clin. Microbiol. 50:3877-3880. http://dx.doi.org/10.1128/JCM.02117-12.
21. Peirano G, van der Bij AK, Gregson DB, Pitout JD. 2012. Molecular epidemiology over an 11-year period (2000 to 2010) of extendedspectrum β-lactamase-producing Escherichia coli causing bacteremia in a centralized Canadian region. J. Clin. Microbiol. 50:294-299. http://dx.doi.org/10.1128/JCM. 06025-11.
22. Poirel L, Bonnin RA, Nordmann P. 2012. Genetic features of the widespread plasmid coding for the carbapenemase OXA-48. Antimicrob. Agents Chemother. 56:559-562. http://dx.doi.org/10.1128/AAC.05289-11.
23. Woodford N, Ellington MJ, Coelho JM, Turton JF, Ward ME, Brown S, Amyes SG, Livermore DM. 2006. Multiplex PCR for genes encoding prevalent OXA carbapenemases in Acinetobacter spp Int. J. Antimicrob. Agents 27:351-353. http://dx.doi.org/10.1016/j.ijantimicag.2006.01.004.
24. Mataseje LF, Boyd DA, Willey BM, Prayitno N, Kreiswirth N, Gelosia A, Poutanen SM, Low DE, Jenkins SG, Katz K, Mulvey MR. 2011. Plasmid comparison and molecular analysis of Klebsiella pneumoniae harbouring bla (KPC) from New York City and Toronto. J. Antimicrob. Chemother. 66:1273-1277. http://dx.doi.org/10. 1093/jac/dkr092.
25. Cuzon G, Naas T, Truong H, Villegas MV, Wisell KT, Carmeli Y, Gales AC, Venezia SN, Quinn JP, Nordmann P. 2010. Worldwide diversity of Klebsiella pneumoniae that produce β-lactamase blaKPC-2 gene. Emerg. Infect. Dis. 16:1349-1356. http://dx.doi.org/10.3201/eid1609.091389.
26. Robicsek A, Strahilevitz J, Sahm DF, Jacoby GA, Hooper DC. 2006. qnr prevalence in ceftazidime-resistant Enterobacteriaceae isolates from the United States. Antimicrob. Agents Chemother. 50:2872-2874. http://dx.doi.org/10.1128/ AAC.01647-05.
27. Robicsek A, Strahilevitz J, Jacoby GA, Macielag M, Abbanat D, Park CH, Bush K, Hooper DC. 2006. Fluoroquinolone-modifying enzyme: a new adaptation of a common aminoglycoside acetyltransferase. Nat. Med. 12:83-88. http://dx.doi.org/10.1038/nm1347.
28. Yamane K, Wachino J, Suzuki S, Arakawa Y. 2008. Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan. Antimicrob. Agents Chemother. 52:1564-1566. http://dx.doi.org/10.1128/AAC.01137-07.
29. Doi Y, Arakawa Y. 2007. 16S ribosomal RNA methylation: emerging resistance mechanism against aminoglycosides. Clin. Infect. Dis. 45:88-94. http://dx.doi.org/10.1086/518605.
30. Hidalgo L, Hopkins KL, Gutierrez B, Ovejero CM, Shukla S, Douthwaite S, Prasad KN, Woodford N, Gonzalez-Zorn B. 2013. Association of the novel aminoglycoside resistance determinant RmtF withNDMcarbapenemase in Enterobacteriaceae isolated in India and the UK. J. Antimicrob. Chemother. 68:1543-1550. http://dx.doi.org/10.1093/jac/dkt078.
31. Diancourt L, Passet V, Verhoef J, Grimont PA, Brisse S. 2005. Multilocus sequence typing of Klebsiella pneumoniae nosocomial isolates. J. Clin. Microbiol. 43:4178-4182. http://dx.doi.org/10.1128/JCM.43.8.417 8-4182.2005.
32. Boyd DA, Tyler S, Christianson S, McGeer A, Muller MP, Willey BM, Bryce E, Gardam M, Nordmann P, Mulvey MR. 2004. Complete nucleotide sequence of a 92-kilobase plasmid harboring the CTX-M-15 extendedspectrum β-lactamase involved in an outbreak in long-term-care facilities in Toronto, Canada. Antimicrob. Agents Chemother. 48:3758-3764. http://dx.doi.org/10.1128/AAC.48.10. 3758-3764.2004.
33. Carattoli A, Bertini A, Villa L, Falbo V, Hopkins KL, Threlfall EJ. 2005. Identification of plasmids by PCR-based replicon typing. J. Microbiol. Methods 63:219-228. http://dx.doi.org/10.1016/j.mimet.2005.03.018.
34. Villa L, Garcia-Fernandez A, Fortini D, Carattoli A. 2010. Replicon sequence typing of IncF plasmids carrying virulence and resistance determinants. J. Antimicrob. Chemother. 65:2518-2529. http://dx.doi.org/10.1093/jac/dkq347.
35. Mnif B, Vimont S, Boyd A, Bourit E, Picard B, Branger C, Denamur E, Arlet G. 2010. Molecular characterization of addiction systems of plasmids encoding extended-spectrum β-lactamases in Escherichia coli. J. Antimicrob. Chemother. 65:1599-1603. http://dx.doi.org/10.1093/jac/dkq181.
36. Johnson JR, Menard M, Johnston B, Kuskowski MA, Nichol K, Zhanel GG. 2009. Epidemic clonal groups of Escherichia coli as a cause of antimicrobialresistant urinary tract infections in Canada, 2002 to 2004. Antimicrob. Agents Chemother. 53:2733-2739. http://dx.doi.org/10.1128/AAC.00297- 09.
37. Brisse S, Fevre C, Passet V, Issenhuth-Jeanjean S, Tournebize R, Diancourt L, Grimont P. 2009. Virulent clones of Klebsiella pneumoniae: identification and evolutionary scenario based on genomic and phenotypic characterization. PLoS One 4:e4982. http://dx.doi.org/10.1371/journal.pone. 0004982.
38. van der Bij AK, Pitout JD. 2012. The role of international travel in the worldwide spread of multiresistant Enterobacteriaceae. J. Antimicrob. Chemother. 67:2090-2100. http://dx.doi.org/10.1093/jac/dks214.
39. Pitout JD, Chow BL, Gregson DB, Laupland KB, Elsayed S, Church DL. 2007. Molecular epidemiology of metallo-β-lactamase-producing Pseudomonas aeruginosa in the Calgary Health Region: emergence of VIM-2-producing isolates. J. Clin. Microbiol. 45:294-298. http://dx.doi.org/10.1128/JCM.01694-06.
40. Osterblad M, Kirveskari J, Hakanen AJ, Tissari P, Vaara M, Jalava J. 2012. Carbapenemase-producing Enterobacteriaceae in Finland: the first years (2008-11). J. Antimicrob. Chemother. 67:2860-2864. http://dx.doi.org/10.1093/ jac/dks299.
41. Giakkoupi P, Papagiannitsis CC, Miriagou V, Pappa O, Polemis M, Tryfinopoulou K, Tzouvelekis LS, Vatopoulos AC. 2011. An update of the evolving epidemic of blaKPC-2-carrying Klebsiella pneumoniae in Greece (2009-10). J. Antimicrob. Chemother. 66:1510-1513. http://dx.doi.org/10.1093/jac/dkr166.
42. Papagiannitsis CC, Kotsakis SD, Petinaki E, Vatopoulos AC, Tzelepi E, Miriagou V, Tzouvelekis LS. 2011. Characterization of metallo-β-lactamase VIM-27, an A57S mutant of VIM-1 associated with Klebsiella pneumoniae ST147. Antimicrob. Agents Chemother. 55:3570-3572. http://dx.doi.org/10.1128/AAC.00238- 11.
43. Hasan CM, Turlej-Rogacka A, Vatopoulos AC, Giakkoupi P, Maatallah M, Giske CG. 2013. Dissemination of blaVIM in Greece at the peak of the epidemic of 2005-2006: clonal expansion of Klebsiella pneumoniae clonal complex 147. Clin. Microbiol. Infect. 20:34-37. http://dx.doi.org/10.1111/1469-0691.12187.
44. Loli A, Tzouvelekis LS, Tzelepi E, Carattoli A, Vatopoulos AC, Tassios PT, Miriagou V. 2006. Sources of diversity of carbapenem resistance levels in Klebsiella pneumoniae carrying blaVIM-1. J. Antimicrob. Chemother. 58:669-672. http://dx.doi.org/10.1093/jac/dkl302.
45. Woodford N, Turton JF, Livermore DM. 2011. Multiresistant Gramnegative bacteria: the role of high-risk clones in the dissemination of antibiotic resistance. FEMS Microbiol. Rev. 35:736-755. http://dx.doi.org/10.1111/j.1574- 6976.2011.00268.x.
46. Jakobsen L, Hammerum AM, Hansen F, Fuglsang-Damgaard D. 2013. An ST405 NDM-4-producing Escherichia coli isolated from a Danish patient previously hospitalized in Vietnam. J. Antimicrob. Chemother. 69:559-560. http://dx.doi.org/10.1093/jac/dkt356.
47. Dobrindt U. 2005. (Patho-) genomics of Escherichia coli. Int. J. Med. Microbiol. 295:357-371. http://dx.doi.org/10.1016/j.ijmm.2005.07.009.
48. Van der Bij AK, Peirano G, Pitondo-Silva A, Pitout JD. 2012. The presence of genes encoding for different virulence factors in clonally related Escherichia coli that produce CTX-Ms. Diagn. Microbiol. Infect. Dis. 72:297-302. http://dx.doi.org/10.1016/j.diagmicrobio.2011.12.011.
49. Rogers BA, Aminzadeh Z, Hayashi Y, Paterson DL. 2011. Country-tocountry transfer of patients and the risk of multiresistant bacterial infection. Clin. Infect. Dis. 53:49-56. http://dx.doi.org/10.1093/cid/cir273.