Evaluation of asthma control, parents' quality of life and preference between AeroChamber Plus and AeroChamber Plus Flow-Vu spacers in young children with asthma

Journal of Asthma

Volumn 52, Issue 3, 2015, Pages 301-307

  Ammari, Wesam G ^a   Toor, Sophie ^b   Chetcuti, Philip ^c   Stephenson, John ^d   Chrystyn, Henry ^d  

^a AL AHLIYYA AMMAN UNIVERSITY   (Jordan)

^b Respiratory Matters ^*  (United Kingdom)

^c LEEDS GENERAL INFIRMARY   (United Kingdom)

^d UNIVERSITY OF HUDDERSFIELD   (United Kingdom)

Author keywords

Caregiver; Infants with asthma; Parents; Quality of life; Spacer; Visual indicator

Indexed keywords

BECLOMETASONE DIPROPIONATE; SALBUTAMOL; CORTICOSTEROID;

ARTICLE; ASTHMA; ASTHMA CONTROL QUESTIONNAIRE; CHILD; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DISEASE CONTROL; FACE MASK; FEEDBACK SYSTEM; FEMALE; HUMAN; INHALATION SPACER; INSPIRATORY FLOW INDICATOR; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; METERED DOSE INHALER; OUTCOME ASSESSMENT; PATIENT PREFERENCE; PEDIATRIC ASTHMA CAREGIVER QUALITY OF LIFE QUESTIONNAIRE; PRESCHOOL CHILD; QUALITY OF LIFE; QUESTIONNAIRE; RANDOMIZED CONTROLLED TRIAL; VISUAL FEEDBACK; INFANT; INHALATIONAL DRUG ADMINISTRATION; PARENT; PATIENT ACUITY; PSYCHOLOGY;

ADMINISTRATION, INHALATION; ADRENAL CORTEX HORMONES; ASTHMA; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; MALE; METERED DOSE INHALERS; PARENTS; PATIENT ACUITY; QUALITY OF LIFE; QUESTIONNAIRES;

EID: 84931077302     PISSN: 02770903     EISSN: 15324303     Source Type: Journal    
DOI: 10.3109/02770903.2014.966111     Document Type: Article

References (45)

1. Newman SP, Moren F, Pavia D, Little F, Clarke SW. Deposition of pressurized suspension aerosols inhaled through extension devices. Am Rev Respir Dis 1981;124:317-320.
2. van Beerendonk I, Mesters I, Mudde AN, Tan TD. Assessment of the inhalation technique in outpatients with asthma or chronic obstructive pulmonary disease using a metered-dose inhaler or dry powder device. J Asthma 1998;35:273-279.
3. Minai BA, Martin JE, Cohn RC. Results of a physician and respiratory therapist collaborative effort to improve long-term metered-dose inhaler technique in a pediatric asthma clinic. Respir Care 2004;49:600-605.
4. Acerbi D, Brambilla G, Kottakis I. Advances in asthma and COPD management: delivering CFC-free inhaled therapy using modulite (r) technology. Pulmonary Pharmacol Ther 2007;20:290-303.
5. Virchow JC, Crompton GK, Dal Negro R, Pedersen S, Magnan A, Seidenbergf J, Barnes PJ. Importance of inhaler devices in the management of airway disease. Respir Med 2008;102:10-19.
6. Everard ML, Devadason SG, Summers QA, Lesouef PN. Factors affecting total and respirable dose delivered by a salbutamol metered-dose inhaler. Thorax 1995;50:746-749.
7. Horsley MG, Bailie GR. Risk-factors for inadequate use of pressurized aerosol inhalers. J Clin Pharm Ther 1988;13:139-143.
8. Larsen JS, Hahn M, Ekholm B, Wick KA. Evaluation of conventional press-and-breathe metered-dose inhaler technique in 501 patients. J Asthma 1994;31:193-199.
9. Everard ML. Role of inhaler competence and contrivance in "difficult asthma". Paediatr Respir Rev 2003;4:135-142.
10. Newman SP, Pavia D, Clarke SW. Simple instructions for using pressurized aerosol bronchodilators. J R Soc Med 1980;73: 776-779.
11. Pedersen S, Frost L, Arnfred T. Errors in inhalation technique and efficiency in inhaler use in asthmatic-children. Allergy 1986;41: 118-124.
12. Dolovich M, Ruffin R, Corr D, Newhouse MT. Clinical-evaluation of a simple demand inhalation mdi aerosol delivery device. Chest 1983;84:36-41.
13. Demirkan K, Tolley E, Mastin T, Soberman J, Burbeck J, Self T. Salmeterol administration by metered-dose inhaler alone vs metered-dose inhaler plus valved holding chamber. Chest 2000; 117:1314-1318.
14. Tobin MJ, Jenouri G, Danta I, Kim C, Watson H, Sackner MA. Response to bronchodilator drug administration by a new reservoir aerosol delivery system and a review of other auxiliary delivery systems. Am Rev Respir Dis 1982;126:670-675.
15. Silkstone VL, Corlett SA, Chrystyn HJ. Relative lung and total systemic bioavailability following inhalation from a metered dose inhaler compared with a metered dose inhaler attached to a large volume plastic spacer and a jet nebuliser. Eur J Clin Pharmacol 2002;57:781-786.
16. Roller CM, Zhang G, Troedson RG, Leach CL, Le Souef PN, Devadason SG. Spacer inhalation technique and deposition of extrafine aerosol in asthmatic children. Eur Respir J 2007;29: 299-306.
17. Toogood JH, Baskerville J, Jennings B, Lefcoe NM, Johansson SA. Use of spacers to facilitate inhaled corticosteroid treatment of asthma. Am Rev Respir Disease 1984;129:723-729.
18. Brown PH, Blundell G, Greening AP, Crompton GK. Do large volume spacer devices reduce the systemic effects of high-dose inhaled corticosteroids. Thorax 1990;45:736-739.
19. The British Guideline on the Management of Asthma. A national clinical guideline [online]. 2012. Available from: http://www. brit-thoracic.org.uk/Portals/0/Guidelines/AsthmaGuidelines/sign 101%20Jan%202012.pdf [last accessed 1 Dec 2013].
20. The Global Strategy for Asthma Management and Prevention. Global initiative for asthma (GINA). 2012. Available from: http:// www.ginasthma.org/local/uploads/files/GINA-Report-March13. pdf [last accessed 15 Dec 2013].
21. Kamps AWA, van Ewijk B, Roorda RJ, Brand PLP. Poor inhalation technique, even after inhalation instructions, in children with asthma. Pediatr Pulmonol 2000;29:39-42.
22. Ammari WG, Chrystyn H. Optimizing the inhalation flow and technique through metered dose inhalers of asthmatic adults and children attending a community pharmacy. J Asthma 2013;50: 505-513.
23. Crompton GK, Barnes PJ, Broeders M, Corrigan C, Corbetta L, Dekhuijzen R, Dubus JC, et al. The need to improve inhalation technique in Europe: A report from the aerosol drug management improvement team. Respir Med 2006;100:1479-1494.
24. Laube BL, Edwards AM, Dalby RN, Creticos PS, Norman PS. The efficacy of slow versus faster inhalation of cromolyn sodium in protecting against allergen challenge in patients with asthma. J Allergy Clin Immunol 1998;101:475-483.
25. Hesselink AE, Penninx BWJH, Wijnhoven HAH, Kreigsman DMW, van Eijk JTM. Determinants of an incorrect inhalation technique in patients with asthma or COPD. Scand J Prim Health Care 2001;19:255-260.
26. Nimmo CJR, Chen DNM, Martinusen SM, Ustad TL, Ostrow DN. Assessment of patient acceptance and inhalation technique of a pressurized aerosol inhaler and 2 breath-actuated devices. Ann Pharmacother 1993;27:922-927.
27. Al-Showair RA, Pearson SB, Chrystyn H. The potential of a 2Tone trainer to help patients use their metered-dose inhalers. Chest 2007; 131:1776-1782.
28. Juniper EF, O'Byrne PM, Guyatt GH, Ferrie PJ, King DR. Development and validation of a questionnaire to measure asthma control. Eur Respir J 1999;14:902-907.
29. Juniper EF, Guyatt GH, Feeny DH, Ferrie PJ, Griffith LE, Townsend M. Measuring quality of life in the parents of children with asthma. Qual Life Res 1996;5:27-34.
30. Pedersen S, Potter P, Dachev S, Bosheva M, Kaczmarek J, Springer E, Dunkel J, Engelstatter R. Efficacy and safety of three ciclesonide doses vs placebo in children with asthma: The rainbow study. Respir Med 2010;104:1618-1628.
31. Mazhar SHRA, Chrystyn H. Salbutamol relative lung and systemic bioavailability of large and small spacers. J Pharm Pharmacol 2008; 60:1609-1613.
32. Nair A, Menzies D, Barnes M, Burns P, McFarlane L, Lipworth BJ. Respirable dose delivery of fluticasone propionate from a small valved holding chamber, a compact breath actuated integrated vortex device and a metered dose inhaler. Br J Clin Pharmacol 2008;66:20-26.
33. Schultz A, Sly PD, Zhang G, Venter A, Le Souef PN, Devadason SG. Incentive device improves spacer technique but not clinical outcome in preschool children with asthma. J Paediatr Child Health 2012;48:52-56.
34. Reznik M, Silver EJ, Cao Y. Evaluation of MDI-spacer utilization and technique in caregivers of urban minority children with persistent asthma. J Asthma 2014;51:149-154.
35. Reznik M, Jaramillo Y, Wylie-Rosett J. Demonstrating and assessing metered-dose inhaler-spacer technique: pediatric care providers' self-reported practices and perceived barriers. Clin Pediatr 2014;53:270-276.
36. Thomas M, Gruffydd-Jones K, Stonham C, Ward S, Macfarlane TV. Assessing asthma control in routine clinical practice: use of the royal college of physicians '3 questions'. Prim Care Respir J 2009; 18:83-88.
37. Garris C, Schatz M, Guilbert T, Davis EA, Bonus T, Bonafede M. Asthma control is predictive of health-related quality of life: survey using the asthma control test (tm) and childhood asthma control test (tm). J Allergy Clin Immunol 2008;121:S149-S149.
38. Stelmach I, Podlecka D, Smejda K, Majak P, Jerzynska J, Stelmach R, Janas A, Stelmach W. Pediatric asthma caregiver's quality of life questionnaire is a useful tool for monitoring asthma in children. Qual Life Res 2012;21:1639-1642.
39. Juniper EF, Bousquet J, Abetz L, Bateman ED, Goal Committee. Identifying 'well-controlled' and 'not well-controlled' asthma using the asthma control questionnaire. Respir Med 2006;100: 616-621.
40. Dolovich M, Ruffin RE, Roberts R, Newhouse MT. Optimal delivery of aerosols from metered dose inhalers. Chest 1981;80: 911-915.
41. Hindle M, Newton DAG, Chrystyn H. Investigations of an optimal inhaler technique with the use of urinary salbutamol excretion as a measure of relative bioavailability to the lung. Thorax 1993;48: 607-610.
42. Newman S, Steed K, Hooper G, Kallen A, Borgstrom L. Comparison of gamma-scintigraphy and a pharmacokinetic technique for assessing pulmonary deposition of terbutaline sulfate delivered by pressurized metered-dose inhaler. Pharm Res 1995;12: 231-236.
43. Farr SJ, Rowe AM, Rubsamen R, Taylor G. Aerosol deposition in the human lung following administration from a microprocessorcontrolled pressurized metered-dose inhaler. Thorax 1995;50: 639-644.
44. Chrystyn H. Effects of device design on patient compliance: comparing the same drug in different devices. Respir Drug Deliv Eur 2009;1:105-116.
45. Amirav I, Newhouse MT, Luder A, Halamish A, Omar H, Gorenberg M. Feasibility of aerosol drug delivery to sleeping infants: A prospective observational study. BMJ Open 2014;4: e004124.