Antibiotic therapy vs appendectomy for treatment of uncomplicated acute appendicitis: The APPAC randomized clinical trial

JAMA - Journal of the American Medical Association

Volumn 313, Issue 23, 2015, Pages 2340-2348

  Salminen, Paulina ^a,b   Paajanen, Hannu ^c,d   Rautio, Tero ^e   Nordström, Pia ^f   Aarnio, Markku ^g   Rantanen, Tuomo ^d,h,i   Tuominen, Risto ^b,j   Hurme, Saija ^b   Virtanen, Johanna ^a   Mecklin, Jukka Pekka ^d,g   Sand, Juhani ^f   Jartti, Airi ^e   Rinta Kiikka, Irina ^f   Grönroos, Juha M ^a,b  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF TURKU   (Finland)

^c MIKKELI CENTRAL HOSPITAL   (Finland)

^d UNIVERSITY OF EASTERN FINLAND   (Finland)

^e OULU UNIVERSITY HOSPITAL   (Finland)

^f TAMPERE UNIVERSITY HOSPITAL   (Finland)

^g JYVÄSKYLÄ CENTRAL HOSPITAL   (Finland)

^h KUOPIO UNIVERSITY HOSPITAL   (Finland)

ⁱ SEINÄJOKI CENTRAL HOSPITAL   (Finland)

^j HOSPITAL DISTRICT OF SOUTHWEST FINLAND   (Finland)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ERTAPENEM; LEVOFLOXACIN; METRONIDAZOLE; ANTIINFECTIVE AGENT; BETA LACTAM;

ACUTE APPENDICITIS; ADULT; ANTIBIOTIC THERAPY; APPENDECTOMY; ARTICLE; COMPARATIVE STUDY; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; FEMALE; FINLAND; FOLLOW UP; HOSPITAL DISCHARGE; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RECURRENT DISEASE; UNCOMPLICATED ACUTE APPENDICITIS; ACUTE DISEASE; ADOLESCENT; APPENDICITIS; APPENDIX; CLINICAL TRIAL; DRUG COMBINATION; EMERGENCY TREATMENT; INTENTION TO TREAT ANALYSIS; INTRAVENOUS DRUG ADMINISTRATION; LAPAROSCOPY; LENGTH OF STAY; PATHOLOGY; POSTOPERATIVE COMPLICATION; TREATMENT FAILURE; YOUNG ADULT;

ACUTE DISEASE; ADMINISTRATION, INTRAVENOUS; ADOLESCENT; ADULT; ANTI-BACTERIAL AGENTS; APPENDECTOMY; APPENDICITIS; APPENDIX; BETA-LACTAMS; DRUG THERAPY, COMBINATION; EMERGENCY TREATMENT; FEMALE; FOLLOW-UP STUDIES; HUMANS; INTENTION TO TREAT ANALYSIS; LAPAROSCOPY; LENGTH OF STAY; LEVOFLOXACIN; MALE; METRONIDAZOLE; POSTOPERATIVE COMPLICATIONS; TREATMENT FAILURE; YOUNG ADULT;

EID: 84931057714     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2015.6154     Document Type: Article

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