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Volumn 28, Issue 3, 2011, Pages 210-221

Surgery versus conservative antibiotic treatment in acute appendicitis: A systematic review and meta-analysis of randomized controlled trials

Author keywords

Acute appendicitis; Antibiotic treatment; Appendectomy; Meta analysis; Systematic review

Indexed keywords

ANTIINFECTIVE AGENT;

EID: 79955423317     PISSN: 02534886     EISSN: None     Source Type: Journal    
DOI: 10.1159/000324595     Document Type: Review
Times cited : (93)

References (65)
  • 1
    • 0000912542 scopus 로고
    • Perforating inflammation of the vermiform appendix
    • Fitz RH: Perforating inflammation of the vermiform appendix. Am J Med Sci 1886; 92: 321-346.
    • (1886) Am J Med Sci , vol.92 , pp. 321-346
    • Fitz, R.H.1
  • 2
    • 0000841796 scopus 로고
    • Experiences with early operative interference in cases of disease of the vermiform appendix
    • McBurney C: Experiences with early operative interference in cases of disease of the vermiform appendix. NY Med J 1889; 50: 1676-1684.
    • (1889) NY Med J , vol.50 , pp. 1676-1684
    • McBurney, C.1
  • 3
    • 2142665785 scopus 로고
    • Appendicitis and antibiotics
    • Harrison PW: Appendicitis and antibiotics. Am J Surg 1953; 85: 160-163.
    • (1953) Am J Surg , vol.85 , pp. 160-163
    • Harrison, P.W.1
  • 4
    • 0004952163 scopus 로고
    • Five years of conservative treatment of acute appendicitis
    • Coldrey E: Five years of conservative treatment of acute appendicitis. J Int Coll Surg 1959; 32: 255-261.
    • (1959) J Int Coll Surg , vol.32 , pp. 255-261
    • Coldrey, E.1
  • 5
    • 0017666293 scopus 로고
    • Anonymous: Combined traditional Chinese and Western medicine for acute appendicitis
    • Anonymous: Combined traditional Chinese and Western medicine for acute appendicitis. Chin Med J 1977; 3: 266-269.
    • (1977) Chin Med J , vol.3 , pp. 266-269
  • 6
    • 0025064421 scopus 로고
    • The medical management of acute appendicitis in a nonsurgical environment: A retrospective case review
    • Adams ML: The medical management of acute appendicitis in a nonsurgical environment: a retrospective case review. Milit Med 1990; 155: 345-347. (Pubitemid 20293998)
    • (1990) Military Medicine , vol.155 , Issue.8 , pp. 345-347
    • Adams, M.L.1
  • 7
    • 0026865153 scopus 로고
    • The efficacy of the conservative treatment of patients with acute appendicitis on board ships at sea
    • Gurin NN, Slobodchuk IUS, Gavrilov IUF: The efficacy of the conservative treatment of patients with acute appendicitis on board ships at sea. Vestn Khir 1992; 148: 144-150.
    • (1992) Vestn Khir , vol.148 , pp. 144-150
    • Gurin, N.N.1    Ius, S.2    Iuf, G.3
  • 8
    • 25144460657 scopus 로고    scopus 로고
    • Routine interval appendectomy is not justified after initial nonoperative treatment of acute appendicitis
    • DOI 10.1001/archsurg.140.9.897
    • Kaminski A, Liu IL, Applebaum H, Lee SL, Haigh PI: Routine interval appendectomy is not justified after initial nonoperative treatment of acute appendicitis. Arch Surg 2005; 140: 897-901. (Pubitemid 41345987)
    • (2005) Archives of Surgery , vol.140 , Issue.9 , pp. 897-901
    • Kaminski, A.1    Liu, I.-L.A.2    Applebaum, H.3    Lee, S.L.4    Haigh, P.I.5
  • 9
    • 2142740422 scopus 로고
    • The treatment of acute appendicitis under suboptimal conditions
    • Bowers WF, Hughes CW, Bonilla KB: The treatment of acute appendicitis under suboptimal conditions. US Armed Forces Med J 1958; 9: 1545-1557.
    • (1958) US Armed Forces Med J , vol.9 , pp. 1545-1557
    • Bowers, W.F.1    Hughes, C.W.2    Bonilla, K.B.3
  • 10
    • 0019878678 scopus 로고
    • A reluctant surgeon at sea
    • Foraker AG: A reluctant surgeon at sea. JAMA 1981; 245: 22: 2302-2303.
    • (1981) JAMA , vol.245 , Issue.22 , pp. 2302-2303
    • Foraker, A.G.1
  • 11
    • 2142824177 scopus 로고    scopus 로고
    • Nonoperative treatment of suspected appendicitis in remote medical care environments: Implications for future spaceflight medical care
    • DOI 10.1016/j.jamcollsurg.2004.01.009, PII S1072751504000407
    • Campbell MR, Johnston SL 3rd, Marshburn T, Kane J, Lugg D: Nonoperative treatment of suspected appendicitis in remote medical care environments: implications for future spaceflight medical care. J Am Coll Surg 2004; 198: 822-830. (Pubitemid 38542911)
    • (2004) Journal of the American College of Surgeons , vol.198 , Issue.5 , pp. 822-830
    • Campbell, M.R.1    Johnston III, S.L.2    Marshburn, T.3    Kane, J.4    Lugg, D.5
  • 12
    • 0027470001 scopus 로고
    • Is it necessary to perform appendicectomy in the middle of the night in children?
    • Surana R, Quinn F, Puri P: Is it necessary to perform appendectomy in the middle of the night in children? BMJ 1993; 306: 1168. (Pubitemid 23121185)
    • (1993) British Medical Journal , vol.306 , Issue.6886 , pp. 1168
    • Surana, R.1    Quinn, F.2    Puri, P.3
  • 13
    • 0021293772 scopus 로고
    • Management of appendiceal abscess
    • Ambjommson E: Management of appendiceal abscess. Curr Surg 1984; 41: 4-9.
    • (1984) Curr Surg , vol.41 , pp. 4-9
    • Ambjommson, E.1
  • 14
    • 0023279470 scopus 로고
    • Nonoperative management of the ultrasonically evaluated appendiceal mass
    • Bagi P, Oueholm S: Non-operative management of the ultrasonically evaluated appendiceal mass. Surgery 1987; 101: 602-605. (Pubitemid 17076099)
    • (1987) Surgery , vol.101 , Issue.5 , pp. 602-605
    • Bagi, P.1    Dueholm, S.2
  • 16
    • 1842862890 scopus 로고    scopus 로고
    • Late abdominal complaints after appendectomy - Readmissions during long-term follow-up
    • DOI 10.1159/000075378
    • Tingstedt B, Johansson J, Nehez L, Andersson R: Late abdominal complaints after appendectomy - readmissions during longterm follow-up. Dig Surg 2004; 21: 23-27. (Pubitemid 38490172)
    • (2004) Digestive Surgery , vol.21 , Issue.1 , pp. 23-27
    • Tingstedt, B.1    Johansson, J.2    Nehez, L.3    Andersson, R.4
  • 17
    • 0034792308 scopus 로고    scopus 로고
    • Small bowel obstruction after appendicectomy
    • DOI 10.1046/j.0007-1323.2001.01869.x
    • Andersson RE: Small bowel obstruction after appendicectomy. Br J Surg 2001; 88: 1387-1391. (Pubitemid 32955422)
    • (2001) British Journal of Surgery , vol.88 , Issue.10 , pp. 1387-1391
    • Andersson, R.E.B.1
  • 19
    • 0036308709 scopus 로고    scopus 로고
    • The clinical and economic correlates of misdiagnosed appendicitis: Nationwide analysis
    • Flum DR, Koepsell T: The clinical and economic correlates of misdiagnosed appendicitis: nationwide analysis. Arch Surg 2002; 137: 799-804. (Pubitemid 34743169)
    • (2002) Archives of Surgery , vol.137 , Issue.7 , pp. 799-804
    • Flum, D.R.1    Koepsell, T.2
  • 20
    • 38449084310 scopus 로고    scopus 로고
    • Can acute appendicitis be treated by antibiotics alone?
    • Liu K, Ahanchi S, Pisaneschi M, Lin I, Walter R: Can acute appendicitis be treated by antibiotics alone? Am Surg 2007; 73: 1161-1165. (Pubitemid 351396529)
    • (2007) American Surgeon , vol.73 , Issue.11 , pp. 1161-1165
    • Liu, K.1    Ahanchi, S.2    Pisaneschi, M.3    Lin, I.4    Walter, R.5
  • 21
    • 0034882503 scopus 로고    scopus 로고
    • Antibiotic treatment of acute appendicitis - Initial observations
    • Salim AS, Ahmed TM: Antibiotic treatment of acute appendicitis - initial observations. Saudi Med J 2001; 22: 643-644. (Pubitemid 32776834)
    • (2001) Saudi Medical Journal , vol.22 , Issue.7 , pp. 643-644
    • Salim, A.S.1    Ahmed, T.M.2
  • 22
    • 34547824309 scopus 로고    scopus 로고
    • Nonoperative treatment of acute appendicitis in children
    • DOI 10.1016/j.jpedsurg.2007.03.049, PII S002234680700190X
    • Abe M, Petik B, Kazil S: Nonoperative treatment of acute appendicitis in children. J Pediatr Surg 2007; 42: 1439-1442. (Pubitemid 47238338)
    • (2007) Journal of Pediatric Surgery , vol.42 , Issue.8 , pp. 1439-1442
    • Abes, M.1    Petik, B.2    Kazil, S.3
  • 24
    • 35649022662 scopus 로고    scopus 로고
    • Nonsurgical treatment of appendiceal abscess or phlegmon: A systematic review and meta-analysis
    • DOI 10.1097/SLA.0b013e31811f3f9f, PII 0000065820071100000009
    • Andersson RE, Petzold MG: Nonsurgical treatment of appendiceal abscess or phlegmon: a systematic review and meta-analysis. Ann Surg 2007; 246: 741-748. (Pubitemid 350035649)
    • (2007) Annals of Surgery , vol.246 , Issue.5 , pp. 741-748
    • Andersson, R.E.1    Petzold, M.G.2
  • 25
    • 0028878582 scopus 로고
    • Randomized controlled trial of appendicectomy versus antibiotic treatment therapy for acute appendicitis
    • Eriksson S, Granström L: Randomized controlled trial of appendicectomy versus antibiotic treatment therapy for acute appendicitis. Br J Surg 1995; 82: 166-169.
    • (1995) Br J Surg , vol.82 , pp. 166-169
    • Eriksson, S.1    Granström, L.2
  • 27
    • 64749106340 scopus 로고    scopus 로고
    • Conservative management of acute appendicitis
    • Malik AA, Bari SU: Conservative management of acute appendicitis. J Gastrointest Surg 2009; 13: 966-970.
    • (2009) J Gastrointest Surg , vol.13 , pp. 966-970
    • Malik, A.A.1    Bari, S.U.2
  • 28
    • 65249160142 scopus 로고    scopus 로고
    • Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients
    • Hansson J, Körner U, Khorram-Manesh A, Solberg A, Lundholm K: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients. Br J Surg 2009; 96: 473-481.
    • (2009) Br J Surg , vol.96 , pp. 473-481
    • Hansson, J.1    Körner, U.2    Khorram-Manesh, A.3    Solberg, A.4    Lundholm, K.5
  • 29
    • 69149107165 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • PRISMA Group
    • Moher D, Liberati A, Tetzlaff J, Altman DG, PRISMA Group: preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 2009; 151: 4/264-269.
    • (2009) Ann Intern Med , vol.151 , Issue.4 , pp. 264-269
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3    Altman, D.G.4
  • 30
    • 68049086808 scopus 로고    scopus 로고
    • Letter 1: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473- 481)
    • Brown E: Letter 1: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473- 481). Br J Surg 2009; 96: 952.
    • (2009) Br J Surg , vol.96 , pp. 952
    • Brown, E.1
  • 32
    • 0035822324 scopus 로고    scopus 로고
    • Assessing the quality of controlled clinical trials
    • Juni P, Altman DG, Egger M: Assessing the quality of controlled clinical trials. BMJ 2001; 323: 42-46.
    • (2001) BMJ , vol.323 , pp. 42-46
    • Juni, P.1    Altman, D.G.2    Egger, M.3
  • 33
    • 0037045587 scopus 로고    scopus 로고
    • Generation of allocation sequences in randomised trials: Chance, not choice
    • DOI 10.1016/S0140-6736(02)07683-3
    • Schulz KF, Grimes DA: Generation of allocation sequences in randomised trials: chance not choice. Lancet 2002; 359: 515-519. (Pubitemid 34164304)
    • (2002) Lancet , vol.359 , Issue.9305 , pp. 515-519
    • Schulz, K.F.1    Grimes, D.A.2
  • 34
    • 0037116839 scopus 로고    scopus 로고
    • Allocation concealment in randomised trials: Defending against deciphering
    • DOI 10.1016/S0140-6736(02)07750-4
    • Schulz KF, Grimes DA: Allocation concealment in randomised trials: defending against deciphering. Lancet 2002; 359: 614-618. (Pubitemid 34178448)
    • (2002) Lancet , vol.359 , Issue.9306 , pp. 614-618
    • Schulz, K.F.1    Grimes, D.A.2
  • 35
    • 0037160763 scopus 로고    scopus 로고
    • Blinding in randomised trials
    • Schultz KF, Grimes AD: Blinding in randomised trials. Lancet 2002; 359: 696-700.
    • (2002) Lancet , vol.359 , pp. 696-700
    • Schultz, K.F.1    Grimes, A.D.2
  • 37
    • 0022505926 scopus 로고
    • Total parenteral nutrition and cancer clinical trials
    • Klein S, Simes J, Blackburn GL: Total parenteral nutrition and clinical cancer trial. Cancer 1986; 58: 1378-1386. (Pubitemid 16053158)
    • (1986) Cancer , vol.58 , Issue.6 , pp. 1378-1386
    • Klein, S.1    Simes, J.2    Blackburn, G.L.3
  • 38
    • 68049115655 scopus 로고    scopus 로고
    • Authors' reply: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473-481)
    • Hansson J, Lundholm K: Authors' reply: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473-481). Br J Surg 2009; 96: 955.
    • (2009) Br J Surg , vol.96 , pp. 955
    • Hansson, J.1    Lundholm, K.2
  • 39
    • 19744376391 scopus 로고
    • The vermiform appendix: Its surgical history
    • Herrington JL: The vermiform appendix: its surgical history. Contemp Surg 1991; 39: 36-44.
    • (1991) Contemp Surg , vol.39 , pp. 36-44
    • Herrington, J.L.1
  • 40
    • 0032190122 scopus 로고    scopus 로고
    • Appendectomy in Sweden 1989-1993 assessed by the inpatient registry
    • DOI 10.1016/S0895-4356(98)00065-1
    • Blomqvist P, Ljung H, Nyren O, Ekbom A: Appendectomy in Sweden 1989-1993 assessed by the Inpatient Registry. J Clin Epidemiol 1998; 51: 859-865. (Pubitemid 28470128)
    • (1998) Journal of Clinical Epidemiology , vol.51 , Issue.10 , pp. 859-865
    • Blomqvist, P.1    Ljung, H.2    Nyren, O.3    Ekbom, A.4
  • 43
    • 0031458325 scopus 로고    scopus 로고
    • High negative appendectomy rates are no longer acceptable
    • DOI 10.1016/S0002-9610(97)00183-9, PII S0002961097001839
    • Colson M, Skinner KA, Dunnington G: High negative appendectomy rates are no longer acceptable. Am J Surg 1997; 174: 723-727. (Pubitemid 28008711)
    • (1997) American Journal of Surgery , vol.174 , Issue.6 , pp. 723-727
    • Colson, M.1    Skinner, K.A.2    Dunnington, G.3
  • 46
    • 10944263935 scopus 로고    scopus 로고
    • The burden of appendicitis-related hospitalizations in the United States in 1997
    • DOI 10.1089/sur.2004.5.160
    • Davies GM, Dasbach EJ, Teutsch S: The burden of appendicitis-related hospitalizations in the United States in 1997. Surg Infect 2004; 5: 160-165. (Pubitemid 40011976)
    • (2004) Surgical Infections , vol.5 , Issue.2 , pp. 160-165
    • Davies, G.M.1    Dasbach, E.J.2    Teutsch, S.3
  • 48
    • 0034592858 scopus 로고    scopus 로고
    • The role of β-lactam antimicrobials as single agents in treatment of intra-abdominal infection
    • Powell LL, Wilson SE: The role of β-lactam antimicrobials as single agents in treatment of intra-abdominal infection. Surg Infect 2000; 1: 57-63.
    • (2000) Surg Infect , vol.1 , pp. 57-63
    • Powell, L.L.1    Wilson, S.E.2
  • 51
    • 0242285652 scopus 로고    scopus 로고
    • Appendiceal abscess: Immediate operation or percutaneous drainage?
    • Brown CV, Abrishami M, Muller M, Velmahos GC: Appendiceal abscess: immediate operation or percutaneous drainage? Am Surg 2003; 69: 829-832.
    • (2003) Am Surg , vol.69 , pp. 829-832
    • Brown, C.V.1    Abrishami, M.2    Muller, M.3    Velmahos, G.C.4
  • 53
    • 84860822495 scopus 로고    scopus 로고
    • Appendectomy versus antibiotic treatment for acute appendicitis (protocol)
    • Art No CD008359 DOI 10.1002/14651858
    • Wilms IMHA, de Hoog DENM, de Visser DC, Janzing HMJ: Appendectomy versus antibiotic treatment for acute appendicitis (protocol). Cochrane Database of Systematic Reviews 2010, Issue 2. Art No CD008359. DOI 10.1002/14651858. CD008359.
    • (2010) Cochrane Database of Systematic Reviews , Issue.2
    • Imha, W.1    De Hoog Denm2    De Visser, D.C.3    Hmj, J.4
  • 54
    • 50849096361 scopus 로고    scopus 로고
    • Surgery for appendicitis: Is it necessary?
    • Mason RJ: Surgery for appendicitis: is it necessary? Surg Infect 2008; 9: 481-488.
    • (2008) Surg Infect , vol.9 , pp. 481-488
    • Mason, R.J.1
  • 55
    • 33846141858 scopus 로고    scopus 로고
    • The natural history and traditional management of appendicitis revisited: Spontaneous resolution and predominance of prehospital perforations imply that a correct diagnosis is more important than an early diagnosis
    • DOI 10.1007/s00268-006-0056-y
    • Andersson RE: The natural history and traditional management of appendicitis revisited: spontaneous resolution and predominance of prehospital perforations imply that a correct diagnosis is more important than an early diagnosis. World J Surg 2007; 31: 86-92. (Pubitemid 46089548)
    • (2007) World Journal of Surgery , vol.31 , Issue.1 , pp. 86-92
    • Andersson, R.E.1
  • 56
    • 0024599557 scopus 로고
    • Incidence and case fatality rates for acute appendicitis in California. A population-based study of the effects of age
    • Luckmann R: Incidence and case fatality rates for acute appendicitis in California. A population-based study of the effects of age. Am J Epidemiol 1989; 129: 905-918. (Pubitemid 19123930)
    • (1989) American Journal of Epidemiology , vol.129 , Issue.5 , pp. 905-918
    • Luckmann, R.1
  • 57
    • 0029068416 scopus 로고
    • Re: Randomized controlled trial of appendicectomy versus antibiotic treatment therapy for acute appendicitis
    • Greig JD, Nixon SJ: Re: Randomized controlled trial of appendicectomy versus antibiotic treatment therapy for acute appendicitis. Br J Surg 1995; 82: 1000.
    • (1995) Br J Surg , vol.82 , pp. 1000
    • Greig, J.D.1    Nixon, S.J.2
  • 58
    • 0029372512 scopus 로고
    • Re: Randomized controlled trial of appendicectomy versus antibiotic treatment therapy for acute appendicitis
    • Ozgüc H, Irgil C, Kaya E, Tokyay R: Re: Randomized controlled trial of appendicectomy versus antibiotic treatment therapy for acute appendicitis. Br J Surg 1995; 82: 1284.
    • (1995) Br J Surg , vol.82 , pp. 1284
    • Ozgüc, H.1    Irgil, C.2    Kaya, E.3    Tokyay, R.4
  • 59
    • 33847628931 scopus 로고    scopus 로고
    • Appendectomy versus antibiotic treatment in acute appendicitis: A prospective multicenter randomized controlled trial [3]
    • DOI 10.1007/s00268-006-0521-7
    • Özgüç H: Re: Appendectomy versus antibiotic treatment in acute appendicitis. A prospective multicenter randomized controlled trial. World J Surg 2007; 31: 615. (Pubitemid 46356089)
    • (2007) World Journal of Surgery , vol.31 , Issue.3 , pp. 615
    • Ozguc, H.1
  • 60
    • 33947624969 scopus 로고    scopus 로고
    • Type II error in a randomized controlled trial of appendectomy vs. antibiotic treatment of acute appendicitis [10]
    • DOI 10.1007/s00268-006-0953-0
    • Søreide K, Kørner H, Søreide JA: Type II error in a randomized controlled trial of appendectomy vs. antibiotic treatment of acute appendicitis. World J Surg 2007; 31: 871-872. (Pubitemid 46496248)
    • (2007) World Journal of Surgery , vol.31 , Issue.4 , pp. 871-872
    • Soreide, K.1    Korner, H.2    Soreide, J.A.3
  • 61
    • 68049092047 scopus 로고    scopus 로고
    • Letter 2: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473-481)
    • Sanabria A, Sanchez C: Letter 2: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473-481). Br J Surg 2009; 96: 952-953.
    • (2009) Br J Surg , vol.96 , pp. 952-953
    • Sanabria, A.1    Sanchez, C.2
  • 62
    • 68049100302 scopus 로고    scopus 로고
    • Letter 3: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473-481)
    • Patel V, Ahamed K, Ashrafian H: Letter 3: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473-481). Br J Surg 2009; 96: 953.
    • (2009) Br J Surg , vol.96 , pp. 953
    • Patel, V.1    Ahamed, K.2    Ashrafian, H.3
  • 63
    • 68049100302 scopus 로고    scopus 로고
    • Letter 4: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473-481)
    • Majumder B: Letter 4: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473-481). Br J Surg 2009; 96: 953-954.
    • (2009) Br J Surg , vol.96 , pp. 953-954
    • Majumder, B.1
  • 64
    • 68049102206 scopus 로고    scopus 로고
    • Letter 5: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473-481)
    • Van Langenber A: Letter 5: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473-481). Br J Surg 2009; 96: 954.
    • (2009) Br J Surg , vol.96 , pp. 954
    • Van Langenber, A.1
  • 65
    • 68049107372 scopus 로고    scopus 로고
    • Letter 6: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473-481)
    • Paice AG, Ali H: Letter 6: Randomized clinical trial of antibiotic therapy versus appendicectomy as primary treatment of acute appendicitis in unselected patients (Br J Surg 2009; 96: 473-481). Br J Surg 2009; 96: 954.
    • (2009) Br J Surg , vol.96 , pp. 954
    • Paice, A.G.1    Ali, H.2


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