Comparison of the efficacy of combination therapy of prednisolone acyclovir with prednisolone alone in Bell’s palsy

Iranian Journal of Child Neurology

Volumn 9, Issue 2, 2015, Pages 17-20

  Khajeh, Ali ^a   Fayyazi, Afshin ^b   Soleimani, Gholamreza ^a   Miri Aliabad, Ghasem ^a   Shaykh Veisi, Sara ^c   Behrouz, Khajeh ^d  

^a ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b HAMADAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c ZAHEDAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d ZABOL UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Acyclovir; Bell s palsy; Children; Prednisolone

Indexed keywords

ACICLOVIR; PREDNISOLONE;

ADOLESCENT; ADULT; AGE; ARTICLE; BELL PALSY; CHILD; CLINICAL ARTICLE; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; CONVALESCENCE; DRUG EFFICACY; FACIAL NERVE PARALYSIS; FEMALE; GENDER; HOUSE BRACKMANN SCALE; HUMAN; MALE; MONOTHERAPY; NEUROLOGIC DISEASE ASSESSMENT; RANDOMIZED CONTROLLED TRIAL;

EID: 84931050011     PISSN: 17354668     EISSN: 20080700     Source Type: Journal    
DOI: None     Document Type: Article

References (24)

1. Numthavaj P, Thakkinstian A, Dejthevaporn CH, et al. Corticosteroid and antiviral therapy for Bell’s palsy: A network meta-analysis. BMC Neurology 2011; 11:1.
2. Atzema C, Goldman RD. Should we use steroids to treat children with Bell’s palsy? Can Fam Physician 2006; 52(3):313–314.
3. Tiemstra JD, Khatkhate N. Bell’s Palsy: Diagnosis and Management. Am Fam Physician 2007; 76(7):997-1002.
4. Jackson CG, von Doersten PG. The facial nerve: Current trends in diagnosis, treatment, and rehabilitation. Med Clin North Am 1999, 83:179-195.
5. John K, Goudakos JK, Markou KD, et al. Corticosteroids vs Corticosteroids Plus Antiviral Agents in the Treatment of Bell Palsy. Arch Otolaryngol Head Neck Surg 2009; 135(6):558-564.
6. Rodrigues de Araujo M, Rodrigues Azenha M, Capelari MM, et al. Management of Bell’s Palsy: A Report of 2 Cases. jcda 2008; 74(9): 823.
7. Kwon HJ, Kim JI, Lee MS, et al. Acupuncture for sequelae of Bell’s palsy: a randomized controlled trial protocol. Trials 2011; 12: 71.
8. Williamson IG, Whelan TR. The clinical problem of Bell’s palsy: is treatment with steroids effective? Br J Gen Pract 1996; 46:743-7.
9. Grogan PM, Gronseth GS. Practice parameter: steroids, acyclovir, and surgery for Bell’s palsy (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2001; 56:830-6.
10. Rowlands S, Hooper R, Hughes R, Burney P. The epidemiology and treatment of Bell’s palsy in the UK. Eur J Neurol 2002; 9:63-7.
11. Holland NJ, Weiner GM. Recent developments in Bell’s palsy. BMJ 2004; 329(7465):553–557.
12. House JW, Brackmann DE. Facial nerve grading system. Otolaryngol Head Neck Surg 1985; 93:146-7.
13. Thaera GM, Wellik KE, Barrs DM, et al. Are corticosteroid and antiviral treatments effective for bell palsy? A critically appraised topic. Neurologist 2010; 16(2):13840.
14. Hato N, Matsumoto S, Kisaki H, et al. Efficacy of early treatment of Bell’s palsy with oral acyclovir and prednisolone. Otol Neurotol 2003; 24:948-51.
15. Ahangar AA, Hosseini S, Saghebi R. Comparison of the efficacy of prednisolone versus prednisolone and acyclovir in the treatment of Bell`s palsy. Neurosciences (Riyadh) 2006; 11(4):256-9.
16. Lee HY, Byun JY, Park MS, et al. Steroid-antiviral treatment improves the recovery rate in patients with severe Bell’s palsy. Am J Med 2013; 126(4):336-41.
17. Axelsson S, Lindberg S, Stjernquist-Desatnik A. Outcome of treatment with valacyclovir and prednisone in patients with Bell’s palsy. Ann Otol Rhinol Laryngol 2003; 112 (3):197-201.
18. Hato N, Yamada H, Kohno H, et al. Valacyclovir and prednisolone treatment for Bell’s palsy: a multicenter, randomized, placebo-controlled study. Otol Neurotol 2007; 28:408-413.
19. Rosenblum R. Combination Treatments for Bell Palsy Can Provide Clinical Benefit. The Journal of the American Dental Association 2010; 141:3 330-331.
20. Shahidullah M, Haque A, Islam MR, et al. Comparative study between combination of famciclovir and prednisolone with prednisolone alone in acute Bell’s palsy. Mymensingh Med J 2011; 20(4):605-13.
21. Sullivan FM, Swan IRC, Donnan PT, et al. Early Treatment with Prednisolone or Acyclovir in Bell’s palsy. N Engl J Med 2007; 357:1598-1607.
22. Kawaguchi K, Inamura H, Abe Y, et al. Reactivation of herpes simplex virus type 1 and varicella-zoster virus and therapeutic effects of combination therapy with prednisolone and valacyclovir in patients with Bell’s palsy. Laryngoscope 2007; 117(1):147-56.
23. Meyer MW, Hahn CH. Treatment of idiopathic peripheral facial nerve paralysis (Bell’s palsy). Ugeskr Laeger 2013 Jan 28;175(5):275-8.
24. Gronseth GS, Paduga R. Evidence-based guideline update: steroids and antivirals for Bell palsy: report of the Guideline Development Subcommittee of the American Academy of Neurology. American Academy of Neurology 2012; 79(22):2209-13.