Corticosteroids vs corticosteroids plus antiviral agents in the treatment of bell palsy: A systematic review and meta-analysis

Archives of Otolaryngology - Head and Neck Surgery

Volumn 135, Issue 6, 2009, Pages 558-564

  Goudakos, John K ^a,b   Markou, Konstantinos D ^a  

^a AHEPA UNIVERSITY HOSPITAL   (Greece)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; CORTICOSTEROID; DEFLAZACORT; PREDNISOLONE; VALACICLOVIR;

ARTICLE; BELL PALSY; CLINICAL TRIAL; COMBINATION CHEMOTHERAPY; CONTROLLED CLINICAL TRIAL; DRUG DOSE REDUCTION; FACIAL NERVE PARALYSIS; HUMAN; META ANALYSIS; RANDOMIZED CONTROLLED TRIAL; SYSTEMATIC REVIEW; TREATMENT OUTCOME; UNSPECIFIED SIDE EFFECT;

ANTIVIRAL AGENTS; BELL PALSY; DRUG THERAPY, COMBINATION; GLUCOCORTICOIDS; HUMANS; ODDS RATIO; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TREATMENT OUTCOME;

EID: 67449168400     PISSN: 08864470     EISSN: 08864470     Source Type: Journal    
DOI: 10.1001/archoto.2009.44     Document Type: Article

References (29)

1. Campbell KE, Brundage JF. Effects of climate, latitude, and season on the incidence of Bell's palsy in the US Armed Forces, October 1997 to September 1999. Am J Epidemiol. 2002;156(1):32-39.
2. Peitersen E. Bell's palsy: the spontaneous course of 2,500 peripheral facial nerve palsies of different etiologies. Acta Otolaryngol Suppl. 2002;(549):4-30. (Pubitemid 35397519)
3. Adour KK. Current concepts in neurology: diagnosis and management of facial paralysis. N Engl J Med. 1982;307(6):348-351. (Pubitemid 12082196)
4. Burgess LP, Yim DW, Lepore ML. Bell's palsy: the steroid controversy revisited. Laryngoscope. 1984;94(11, pt 1):1472-1476. (Pubitemid 15183630)
5. Lorber B. Are all diseases infectious? Ann Intern Med. 1996;125(10):844-851. (Pubitemid 126449724)
6. McCormick DP. Herpes-simplex virus as a cause of Bell's palsy. Lancet. 1972;1(7757):937-939.
7. Takasu T, Furuta Y, Sato KC, Fukuda S, Inuyama Y, Nagashima K. Detection of latent herpes simplex virus DNA and RNA in human geniculate ganglia by the polymerase chain reaction. Acta Otolaryngol. 1992;112(6):1004-1011.
8. Murakami S, Mizobuchi M, Nakashiro Y, Doi T, Hato N, Yanagihara N. Bell palsy and herpes simplex virus: identification of viral DNA in endoneurial fluid and muscle. Ann Intern Med. 1996;124(1, pt 1):27-30. (Pubitemid 26019621)
9. Cawthorne T. The pathology and surgical treatment of Bell's palsy. J Laryngol Otol. 1951;65(11):792-804.
10. Fowler EP Jr. Medical and surgical treatment of Bell's palsy. Laryngoscope. 1958;68(9):1655-1662.
11. Ramsey MJ, DerSimonian R, Holtel MR, Burgess LP. Corticosteroid treatment for idiopathic facial nerve paralysis: a meta-analysis. Laryngoscope. 2000;110(3, pt 1):335-341. (Pubitemid 30143671)
12. Salinas RA, Alvarez G, Ferreira J. Corticosteroids for Bell's palsy (idiopathic facial paralysis). Cochrane Database Syst Rev. 2004;(4):CD001942.
13. Allen D, Dunn L. Aciclovir or valaciclovir for Bell's palsy (idiopathic facial paralysis). Cochrane Database Syst Rev. 2004;(3):CD001869.
14. Hato N, Yamada H, Kohno H, et al. Valacyclovir and prednisolone treatment for Bell's palsy: a multicenter, randomized, placebo-controlled study. Otol Neurotol. 2007;28(3):408-413. (Pubitemid 46607918)
15. Sullivan FM, Swan IR, Donnan PT, et al. Early treatment with prednisolone or acyclovir in Bell's palsy. N Engl J Med. 2007;357(16):1598-1607. (Pubitemid 47598402)
16. Cochrane Library. Issue 1, 2008. www3.interscience.wiley.com/cgi-bin/ mrwhome/106568753/HOME. Accessed February 1, 2008.
17. Adour KK, Ruboyianes JM, Von Doersten PG, et al. Bell's palsy treatment with acyclovir and prednisone compared with prednisone alone: a double-blind, randomized, controlled trial. Ann Otol Rhinol Laryngol. 1996;105(5):371-378. (Pubitemid 26160650)
18. Melo E, Antunes M, Ferreira PL. Quality of life in patients undergoing coronary revascularization. Rev Port Cardiol. 2000;19(9):889-906.
19. Inanli S, Tutkun A, Ozturk O, et al. Idiopathic facial nerve paralysis treatment with acyclovir and prednisolone alone. Turkish Arch Otol. 2001;39:19-24.
20. House JW, Brackmann DE. Facial nerve grading system. Otolaryngol Head Neck Surg. 1985;93(2):146-147.
21. Mantel N, Haenszel WH. Statistical aspects of the analysis of data from retrospective studies of diseases. J Natl Cancer Inst. 1959;22(4):719-748.
22. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7(3):177-188. (Pubitemid 17189972)
23. Kawaguchi K, Inamura H, Abe Y, et al. Reactivation of herpes simplex virus type 1 and varicella-zoster virus and therapeutic effects of combination therapy with prednisolone and valacyclovir in patients with Bell's palsy. Laryngoscope. 2007;117(1):147-156. (Pubitemid 46066078)
24. Lagalla G, Logullo F, Di Bella P, Provinciali L, Ceravolo MG. Influence of early high-dose steroid treatment on Bell's palsy evolution. Neurol Sci. 2002;23(3):107-112. (Pubitemid 35345481)
25. De Diego JI, Prim MP, De Sarria MJ, Madero R, Gavilán J. Idiopathic facial paralysis: a randomized, prospective, and controlled study using single-dose prednisone versus acyclovir three times daily. Laryngoscope. 1998;108(4, pt 1):573-575. (Pubitemid 28166873)
26. Grosheva M, Guntinas-Lichius O. Significance of electromyography to predict and evaluate facial function outcome after acute peripheral facial palsy. Eur Arch Otorhinolaryngol. 2007;264(12):1491-1495. (Pubitemid 350112395)
27. Furuta Y, Ohtani F, Kawabata H, Fukuda S, Bergström T. High prevalence of varicellazoster virus reactivation in herpes simplex virus-seronegative patients with acute peripheral facial palsy. Clin Infect Dis. 2000;30(3):529-533. (Pubitemid 30205300)
28. Hollis S, Campbell F. What is meant by intention to treat analysis? survey of published randomised controlled trials. BMJ. 1999;319(7211):670-674. (Pubitemid 29423954)
29. Gravel J, Opatrny L, Shapiro S. The intention-to-treat approach in randomized controlled trials: are authors saying what they do and doing what they say? Clin Trials. 2007;4(4):350-356. (Pubitemid 47572267)