Topical and intravenous tranexamic acid reduce blood loss compared to routine hemostasis in total knee arthroplasty: a multicenter, randomized, controlled trial

Archives of Orthopaedic and Trauma Surgery

Volumn 135, Issue 7, 2015, Pages 1017-1025

  Aguilera, X ^a   Martinez Zapata M J ^b   Hinarejos, P ^c   Jordan M ^a   Leal, J ^c   Gonzalez J C ^a   Monllau, J C ^c   Celaya, F ^a   Rodriguez Arias A ^a   Fernandez J A ^a   Pelfort, X ^c   Puig Verdie, L ^c  

^a HOSPITAL DE LA SANTA CREU I SANT PAU   (Spain)

^b BIOMEDICAL RESEARCH INSTITUTE SANT PAU IIB SANT PAU   (Spain)

^c Parc de Salut Mar   (Spain)

Author keywords

Blood loss; Topical and intravenous tranexamic acid; Total knee arthroplasty; Transfusion

Indexed keywords

TRANEXAMIC ACID; ANTIFIBRINOLYTIC AGENT;

ADULT; ADVERSE OUTCOME; AGED; ARTICLE; BLOOD TRANSFUSION; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; ELECTROCOAGULATION; EVIDENCE BASED MEDICINE; FEMALE; HEMOSTASIS; HUMAN; JOINT DEGENERATION; KNEE DISEASE; KNEE OSTEOARTHRITIS; KNEE PROSTHESIS; MAJOR CLINICAL STUDY; MALE; MORTALITY; MULTICENTER STUDY; OPEN STUDY; OPERATIVE BLOOD LOSS; OUTCOME ASSESSMENT; PARALLEL DESIGN; PHYSIOTHERAPY; PRIORITY JOURNAL; PROSTHESIS DISLOCATION; PROSTHESIS INFECTION; RANDOMIZED CONTROLLED TRIAL; REHABILITATION CARE; RHEUMATOID ARTHRITIS; TOTAL KNEE REPLACEMENT; BLOOD LOSS, SURGICAL; CLINICAL TRIAL; INTRADERMAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; KNEE ARTHROPLASTY; MIDDLE AGED; POSTOPERATIVE HEMORRHAGE; PROCEDURES; SPAIN; TREATMENT OUTCOME; VERY ELDERLY;

ADMINISTRATION, CUTANEOUS; AGED; AGED, 80 AND OVER; ANTIFIBRINOLYTIC AGENTS; ARTHROPLASTY, REPLACEMENT, KNEE; BLOOD LOSS, SURGICAL; FEMALE; HEMOSTASIS; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; POSTOPERATIVE HEMORRHAGE; SPAIN; TRANEXAMIC ACID; TREATMENT OUTCOME;

EID: 84931010660     PISSN: 09368051     EISSN: 14343916     Source Type: Journal    
DOI: 10.1007/s00402-015-2232-8     Document Type: Article

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