Comparative studies on proliferation, molecular markers and differentiation potential of mesenchymal stem cells from various tissues (adipose, bone marrow, ear skin, abdominal skin, and lung) and maintenance of multipotency during serial passages in miniature pig

Research in Veterinary Science

Volumn 100, Issue , 2015, Pages 115-124

  Lee, Ah Young ^a   Lee, Jienny ^a   Kim, Chan Lan ^a   Lee, Keum Sil ^a   Lee, So Hyun ^a   Gu, Na Yeon ^a   Kim, Jeong Min ^a   Lee, Byeong Chun ^b   Koo, Ok Jae ^b   Song, Jae Young ^a   Cha, Sang Ho ^a  

^a Animal Plant and Fisheries Quarantine and Inspection Agency   (South Korea)

^b Seoul National University   (South Korea)

Author keywords

Differentiation; Mesenchymal stem cells; Miniature pig; Multipotency; Proliferation

Indexed keywords

BETA1 INTEGRIN; CD34 ANTIGEN; CD45 ANTIGEN; ENDOGLIN; HERMES ANTIGEN; OCTAMER TRANSCRIPTION FACTOR 4; THY 1 ANTIGEN; TRANSCRIPTION FACTOR NANOG; TRANSCRIPTION FACTOR SOX2; BIOLOGICAL MARKER;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; BONE MARROW; CARTILAGE CELL; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; COMPARATIVE STUDY; CONTROLLED STUDY; GENE EXPRESSION; LUNG PARENCHYMA; MESENCHYMAL STEM CELL; NONHUMAN; OSTEOBLAST; PHENOTYPIC VARIATION; SKIN; STEM CELL CULTURE; YUCATAN MICROPIG; ANIMAL; ANTIBODY SPECIFICITY; CYTOLOGY; MESENCHYMAL STROMA CELL; METABOLISM; MINIPIG; PIG; VETERINARY; VIRUS CULTURE;

SUIDAE;

ANIMALS; BIOMARKERS; CELL DIFFERENTIATION; CELL PROLIFERATION; MESENCHYMAL STROMAL CELLS; ORGAN SPECIFICITY; SERIAL PASSAGE; SWINE; SWINE, MINIATURE;

EID: 84930927276     PISSN: 00345288     EISSN: 15322661     Source Type: Journal    
DOI: 10.1016/j.rvsc.2015.03.010     Document Type: Article

References (34)

1. Al-Nbaheen M., Vishnubalaji R., Ali D., Bouslimi A., Al-Jassir F., Megges M., et al. Human stromal (mesenchymal) stem cells from bone marrow, adipose tissue and skin exhibit differences in molecular phenotype and differentiation potential. Stem Cell Reviews 2013, 9:32-43.
2. Arufe M.C., De la Fuente A., Fuentes-Boquete I., De Toro F.J., Blanco F.J. Differentiation of synovial CD-105(+) human mesenchymal stem cells into chondrocyte-like cells through spheroid formation. Journal of Cellular Biochemistry 2009, 108:145-155.
3. Banfi A., Muraglia A., Dozin B., Mastrogiacomo M., Cancedda R., Quarto R. Proliferation kinetics and differentiation potential of ex vivo expanded human bone marrow stromal cells: implications for their use in cell therapy. Experimental Hematology 2000, 28:707-715.
4. Bonab M.M., Alimoghaddam K., Talebian F., Ghaffari S.H., Ghavamzadeh A., Nikbin B. Aging of mesenchymal stem cell in vitro. BMC Cell Biology 2006, 10:7-14.
5. Bosch P., Pratt S.L., Stice S.L. Isolation, characterization, gene modification, and nuclear reprogramming of porcine mesenchymal stem cells. Biology of Reproduction 2006, 74:46-57.
6. Branco É., Cabral R., Gomes B.D., Kfoury J.R., Miglino M.A. Bone marrow cells of swine: collection and separation. Microscopy Research and Technique 2012, 75:917-920.
7. Carlin R., Davis D., Weiss M., Schultz B., Troyer D. Expression of early transcription factors Oct-4, Sox-2 and Nanog by porcine umbilical cord (PUC) matrix cells. Reproductive Biology and Endocrinology 2006, 4:8-20.
8. Chen J., Lu Z., Cheng D., Peng S., Wang H. Isolation and characterization of porcine amniotic fluid-derived multipotent stem cells. PLoS ONE 2011, 6:e19964.
9. Digirolamo C.M., Stokes D., Colter D., Phinney D.G., Class R., Prockop D.J. Propagation and senescence of human marrow stromal cells in culture: a simple colony-forming assay identifies samples with the greatest potential to propagate and differentiate. British Journal of Haematology 1999, 107:275-281.
10. Dyce P.W., Zhu H., Craig J., Li J. Stem cells with multilineage potential derived from porcine skin. Biochemical and Biophysical Research Communications 2004, 316:651-658.
11. Esteban M.A., Xu J., Yang J., Peng M., Qin D., Li W., et al. Generation of induced pluripotent stem cell lines from Tibetan miniature pig. The Journal of Biological Chemistry 2009, 284:17634-17640.
12. Galderisi U., Helmbold H., Squillaro T., Alessio N., Komm N., Khadang B., et al. In vitro senescence of rat mesenchymal stem cells is accompanied by downregulation of stemness-related and DNA damage repair genes. Stem Cells and Development 2009, 18:1033-1042.
13. Gu P., Harwood L.J., Zhang X., Wylie M., Curry W.J., Cogliati T. Isolation of retinal progenitor and stem cells from the porcine eye. Molecular Vision 2007, 13:1045-1057.
14. Ishimura D., Yamamoto N., Tajima K., Ohno A., Yamamoto Y., Washimi O., et al. Differentiation of adipose-derived stromal vascular fraction culture cells into chondrocytes using the method of cell sorting with a mesenchymal stem cell marker. The Tohoku Journal of Experimental Medicine 2008, 216:149-156.
15. Juhásová J., Juhás S., Klíma J., Strnádel J., Holubová M., Motlík J. Osteogenic differentiation of miniature pig mesenchymal stem cells in 2D and 3D environment. Physiological Research 2011, 60:559-571.
16. Kumar G., Hara H., Long C., Shaikh H., Ayares D., Cooper D.K., et al. Adipose-derived mesenchymal stromal cells from genetically modified pigs: immunogenicity and immune modulatory properties. Cytotherapy 2012, 14:494-504.
17. Lee K.S., Nah J.J., Lee B.C., Lee H.T., Lee H.S., So B.J., et al. Maintenance and characterization of multipotent mesenchymal stem cells isolated from canine umbilical cord matrix by collagenase digestion. Research in Veterinary Science 2013, 94:144-151.
18. Lermen D., Gorjup E., Dyce P.W., von Briesen H., Müller P. Neuro-muscular differentiation of adult porcine skin derived stem cell-like cells. PLoS ONE 2010, 5:e8968.
19. Livak K.J., Schmittgen T.D. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods (San Diego, Calif.) 2001, 25:402-408.
20. Majumdar M.K., Banks V., Peluso D.P., Morris E.A. Isolation, characterization, and chondrogenic potential of human bone marrow-derived multipotential stromal cells. Journal of Cellular Physiology 2000, 185:98-106.
21. Matsumoto S., Okumura K., Ogata A., Hisatomi Y., Sato A., Hattori K., et al. Isolation of tissue progenitor cells from duct-ligated salivary glands of swine. Cloning and Stem Cells 2007, 9:176-190.
22. Muraglia A., Cancedda R., Quarto R. Clonal mesenchymal progenitors from human bone marrow differentiate in vitro according to a hierarchical model. Journal of Cell Science 2000, 113:1161-1166.
23. Ock S.A., Jeon B.G., Rho G.J. Comparative characterization of porcine mesenchymal stem cells derived from bone marrow extract and skin tissues. Tissue Engineering. Part C, Methods 2010, 16:1481-1491.
24. Qu C.Q., Zhang G.H., Zhang L.J., Yang G.S. Osteogenic and adipogenic potential of porcine adipose mesenchymal stem cells. In Vitro Cellular and Developmental Biology. Animal 2007, 43:95-100.
25. Racanicchi L., Basta G., Montanucci P., Guido L., Pensato A., Conti V., et al. Neonatal pig liver-derived progenitors for insulin-producing cells: an in vitro study. Tissue Engineering 2007, 13:2923-2931.
26. Ringe J., Kaps C., Schmitt B., Büscher K., Bartel J., Smolian H., et al. Porcine mesenchymal stem cells. Induction of distinct mesenchymal cell lineages. Cell and Tissue Research 2002, 307:321-327.
27. Sachs D.H., Galli C. Genetic manipulation in pigs. Current Opinion in Organ Transplantation 2009, 14:148-153.
28. Safwani W.K., Makpol S., Sathapan S., Chua K.H. Alteration of gene expression levels during osteogenic induction of human adipose derived stem cells in long-term culture. Cell and Tissue Banking 2013, 14:289-301.
29. Song S.H., Kumar B.M., Kang E.J., Lee Y.M., Kim T.H., Ock S.A., et al. Characterization of porcine multipotent stem/stromal cells derived from skin, adipose, and ovarian tissues and their differentiation in vitro into putative oocyte-like cells. Stem Cells 2011, 20:1359-1370.
30. Sotiropoulou P.A., Perez S.A., Salagianni M., Baxevanis C.N., Papamichail M. Characterization of the optimal culture conditions for clinical scale production of human mesenchymal stem cells. Stem Cells 2006, 24:462-471.
31. Wagner W., Wein F., Seckinger A., Frankhauser M., Wirkner U., Krause U., et al. Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood. Experimental Hematology 2005, 33:1402-1416.
32. Williams K.J., Picou A.A., Kish S.L., Giraldo A.M., Godke R.A., Bondioli K.R. Isolation and characterization of porcine adipose tissue-derived adult stem cells. Cells, Tissues, Organs 2008, 188:251-258.
33. Yang S.R., Cho S.D., Ahn N.S., Jung J.W., Park J.S., Jo E.H., et al. The role of p38 MAP kinase and c-Jun N-terminal protein kinase signaling in the differentiation and apoptosis of immortalized neural stem cells. Mutation Research 2005, 579:47-57.
34. Zeng L., Rahrmann E., Hu Q., Lund T., Sandquist L., Felten M., et al. Multipotent adult progenitor cells from swine bone marrow. Stem Cells 2006, 24:2355-2366.