New anti-trypanosomal active tetracyclic iridoid isolated from Morinda lucida Benth.

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 15, 2015, Pages 3030-3033

  Suzuki, Mitsuko ^a,b   Tung, Nguyen Huu ^c,e   Kwofie, Kofi D ^a   Adegle, Richard ^d   Amoa Bosompem, Michael ^a   Sakyiamah, Maxwell ^d   Ayertey, Frederick ^d   Owusu, Kofi Baffour Awuah ^a   Tuffour, Isaac ^a   Atchoglo, Philip ^a   Frempong, Kwadwo Kyereme ^a   Anyan, William K ^a   Uto, Takuhiro ^c   Morinaga, Osamu ^c   Yamashita, Taizo ^c   Aboagye, Frederic ^d   Appiah, Alfred Ampomah ^d   Appiah Opong, Regina ^a   Nyarko, Alexander K ^a   Yamaoka, Shoji ^b   Yamaguchi, Yasuchika ^c   Edoh, Dominic ^d   Koram, Kwadwo ^a   Ohta, Nobuo ^b   Boakye, Daniel A ^a   Ayi, Irene ^a   Shoyama, Yukihiro ^c   more..

^a University of Ghana   (Ghana)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^c NAGASAKI INTERNATIONAL UNIVERSITY   (Japan)

^d Centre for Scientific Research into Plant Medicine   (Ghana)

^e VIETNAM NATIONAL UNIVERSITY   (Viet Nam)

Author keywords

Anti trypanosomal activity; Medicinal plants; Molucidin; Morinda lucida; Tetracyclic iridoid

Indexed keywords

ANTITRYPANOSOMAL AGENT; IRIDOID; MOLUCIDIN; MORINDA LUCIDA EXTRACT; OREGONIN; PLANT EXTRACT; UNCLASSIFIED DRUG;

AFRICA; AFRICAN TRYPANOSOMIASIS; ANTIPROTOZOAL ACTIVITY; ARTICLE; BIOASSAY; CARBON NUCLEAR MAGNETIC RESONANCE; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG POTENCY; DRUG PURIFICATION; FRACTIONATION; HETERONUCLEAR MULTIPLE BOND CORRELATION; HETERONUCLEAR MULTIPLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; IC50; MORINDA LUCIDA; NONHUMAN; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION; ANIMAL; CELL LINE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; ISOLATION AND PURIFICATION; MORINDA; TRYPANOSOMA; TRYPANOSOMIASIS, AFRICAN; TUMOR CELL LINE;

ALNUS JAPONICA; MORINDA LUCIDA; PROTOZOA;

ANIMALS; CELL LINE; CELL LINE, TUMOR; HUMANS; IRIDOIDS; MODELS, MOLECULAR; MORINDA; PLANT EXTRACTS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA; TRYPANOSOMIASIS, AFRICAN;

EID: 84930924861     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.05.003     Document Type: Article

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