Neuropeptide Y regulates the hematopoietic stem cell microenvironment and prevents nerve injury in the bone marrow

EMBO Journal

Volumn 34, Issue 12, 2015, Pages 1648-1660

  Park, Min Hee ^a,b   Jin, Hee Kyung ^a   Min, Woo Kie ^c   Lee, Won Woo ^d   Lee, Jeong Eun ^c   Akiyama, Haruhiko ^e   Herzog, Herbert ^f   Enikolopov, Grigori N ^g   Schuchman, Edward H ^h   Bae, Jae Sung ^a,b  

^a Kyungpook National University   (South Korea)

^b Kyungpook National University School of Medicine   (South Korea)

^c Kyungpook National University Hospital   (South Korea)

^d Seoul National University College of Medicine   (South Korea)

^e KYOTO UNIVERSITY   (Japan)

^f GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^g Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^h MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Bone marrow microenvironment; Hematopoietic stem cell; Neuropeptide Y; Regeneration; Sympathetic nervous system

Indexed keywords

CISPLATIN; NESTIN; NEUROPEPTIDE Y; NEUROPEPTIDE Y RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BONE MARROW CELL; BONE MARROW DEPRESSION; CELL COUNT; CELL REGENERATION; CELL SURVIVAL; CONTROLLED STUDY; ENDOTHELIUM CELL; EXPERIMENTAL CHEMOTHERAPY-INDUCED NEUROPATHY; FEMALE; HEMATOPOIETIC STEM CELL; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT MOUSE; MACROPHAGE; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; OSTEOBLAST; PC12 CELL LINE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSORY NEUROPATHY; ADRENERGIC SYSTEM; ANALYSIS OF VARIANCE; ANIMAL; BONE MARROW; CYTOLOGY; DEFICIENCY; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; METABOLISM; MYELINATED NERVE; PHYSIOLOGY; TUMOR MICROENVIRONMENT;

MUS;

ANALYSIS OF VARIANCE; ANIMALS; APOPTOSIS; BONE MARROW; BONE MARROW CELLS; CELLULAR MICROENVIRONMENT; ENDOTHELIAL CELLS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HEMATOPOIETIC STEM CELLS; MICE; MICE, KNOCKOUT; NERVE FIBERS, MYELINATED; NEUROPEPTIDE Y; SYMPATHETIC NERVOUS SYSTEM;

EID: 84930872362     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.15252/embj.201490174     Document Type: Article

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