Albumin impairs renal tubular tight junctions via targeting the NLRP3 inflammasome

American Journal of Physiology - Renal Physiology

Volumn 308, Issue 9, 2015, Pages F1012-F1019

  Zhuang, Yibo ^a,b,c   Hu, Caiyu ^a,b   Ding, Guixia ^a,b   Zhang, Yue ^a,b   Huang, Songming ^a,b   Jia, Zhanjun ^a,b   Zhang, Aihua ^a,b  

^a NANJING MEDICAL UNIVERSITY   (China)

^b Jiangsu Key Laboratory of Pediatric Respiratory Disease   (China)

^c THE THIRD AFFILIATED HOSPITAL OF SOOCHOW UNIVERSITY   (China)

Author keywords

Albumin; Claudin 1; Tight junction; Zonula occludens 1

Indexed keywords

ALBUMIN; CLAUDIN 1; CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA CONVERTING ENZYME; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; NEURONAL APOPTOSIS INHIBITORY PROTEIN; NLRP3 INFLAMMASOME; PROTEIN ZO1; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; BOVINE SERUM ALBUMIN; CARRIER PROTEIN; CIAS1 PROTEIN, MOUSE; CLDN1 PROTEIN, MOUSE; MESSENGER RNA; TJP1 PROTEIN, MOUSE;

ALBUMINURIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM CELL; GENE SILENCING; IMMUNOHISTOCHEMISTRY; KIDNEY TUBULE CELL; KIDNEY TUBULE DAMAGE; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; MORPHOLOGY; MOUSE; NONHUMAN; PERIODIC ACID SCHIFF STAIN; PODOSPORA ANSERINA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; REAL TIME POLYMERASE CHAIN REACTION; TIGHT JUNCTION; TRANSMISSION ELECTRON MICROSCOPY; URINARY EXCRETION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL LINE; CHEMICALLY INDUCED; DISEASE MODEL; GENETIC TRANSFECTION; GENETICS; IMMUNOLOGY; KIDNEY PROXIMAL TUBULE; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; PERMEABILITY; RNA INTERFERENCE; TIME; ULTRASTRUCTURE;

ALBUMINURIA; ANIMALS; CARRIER PROTEINS; CASPASE 1; CELL LINE; CLAUDIN-1; DISEASE MODELS, ANIMAL; INFLAMMASOMES; KIDNEY TUBULES, PROXIMAL; MALE; MICE, INBRED C57BL; MICE, KNOCKOUT; PERMEABILITY; RNA INTERFERENCE; RNA, MESSENGER; SERUM ALBUMIN, BOVINE; TIGHT JUNCTIONS; TIME FACTORS; TRANSFECTION; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84930838987     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00509.2014     Document Type: Article

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