Complete destruction of deep-tissue buried tumors via combination of gene silencing and gold nanoechinus-mediated photodynamic therapy

Biomaterials

Volumn 62, Issue , 2015, Pages 13-23

  Vijayaraghavan, Priya ^a   Vankayala, Raviraj ^a   Chiang, Chi Shiun ^a   Sung, Hsing Wen ^a   Hwang, Kuo Chu ^a  

^a NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

Biological window; Deep tissue buried tumors; Gene silencing; Gold nanoechinus; Nanomaterial mediated photodynamic therapy; Singlet oxygen

Indexed keywords

DISEASES; GENES; GENETIC ENGINEERING; GOLD; MAMMALS; NONINVASIVE MEDICAL PROCEDURES; TUMORS;

COMBINED THERAPY; GENE SILENCING; INVASIVE THERAPY; LIGHT IRRADIATIONS; PHOTODYNAMIC THERAPY (PDT); SINGLET OXYGEN; THERAPEUTIC MODALITY; TUMOR SUPPRESSION;

PHOTODYNAMIC THERAPY;

DOXORUBICIN; GOLD NANOPARTICLE; SMALL INTERFERING RNA; GOLD; METAL NANOPARTICLE; NANOCAPSULE; PHOTOSENSITIZING AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER CELL DESTRUCTION; CANCER GROWTH; CANCER INHIBITION; CANCER LOCALIZATION; CANCER SIZE; CANCER SURVIVAL; CELL COUNT; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CHEMICAL STRUCTURE; COMPLEX FORMATION; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DNA SYNTHESIS; DOWN REGULATION; ENZYME ACTIVITY; GENE SILENCING; HUMAN; HUMAN CELL; HYPERPOLARIZATION; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; LIFESPAN; MALE; MELANOMA CELL LINE; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; MULTIMODALITY CANCER THERAPY; NONHUMAN; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STATIC ELECTRICITY; ZETA POTENTIAL; ANIMAL; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; GENE THERAPY; GENETICS; HELA CELL LINE; NEOPLASMS, EXPERIMENTAL; PATHOLOGY; PHOTOCHEMOTHERAPY; PROCEDURES; RADIATION RESPONSE; TREATMENT OUTCOME; ULTRASTRUCTURE;

MUS; NES;

ANIMALS; CELL SURVIVAL; COMBINED MODALITY THERAPY; GENE SILENCING; GENETIC THERAPY; GOLD; HELA CELLS; HUMANS; METAL NANOPARTICLES; MICE; NANOCAPSULES; NEOPLASMS, EXPERIMENTAL; PHOTOCHEMOTHERAPY; PHOTOSENSITIZING AGENTS; RNA, SMALL INTERFERING; TREATMENT OUTCOME;

EID: 84930810634     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.05.039     Document Type: Article

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