메뉴 건너뛰기




Volumn 100, Issue 6, 2015, Pages 2329-2338

A pooled analysis of the effects of conjugated estrogens/bazedoxifene on lipid parameters in postmenopausal women from the Selective estrogens, Menopause, And Response to Therapy (SMART) Trials

Author keywords

[No Author keywords available]

Indexed keywords

BAZEDOXIFENE PLUS CONJUGATED ESTROGEN; CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; TRIACYLGLYCEROL; BAZEDOXIFENE; CONJUGATED ESTROGEN; INDOLE DERIVATIVE; LIPID; SELECTIVE ESTROGEN RECEPTOR MODULATOR;

EID: 84930808067     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2014-2649     Document Type: Article
Times cited : (38)

References (44)
  • 2
    • 84881520419 scopus 로고    scopus 로고
    • A comparative study of lipid profile and oestradiol in pre- and post-menopausal women
    • Reddy Kilim S, Chandala SR. A comparative study of lipid profile and oestradiol in pre- and post-menopausal women. J Clin Diagn Res. 2013;7:1596-1598.
    • (2013) J Clin Diagn Res , vol.7 , pp. 1596-1598
    • Reddy Kilim, S.1    Chandala, S.R.2
  • 3
    • 0031759142 scopus 로고    scopus 로고
    • Associations between low levels of serum estradiol, bone density, and fractures among elderly women: The study of osteoporotic fractures
    • Ettinger B, Pressman A, Sklarin P, Bauer DC, Cauley JA, Cummings SR. Associations between low levels of serum estradiol, bone density, and fractures among elderly women: the study of osteoporotic fractures. J Clin Endocrinol Metab. 1998;83:2239-2243.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 2239-2243
    • Ettinger, B.1    Pressman, A.2    Sklarin, P.3    Bauer, D.C.4    Cauley, J.A.5    Cummings, S.R.6
  • 5
    • 0027459108 scopus 로고
    • Influence of age and menopause on serum lipids and lipoproteins in healthy women
    • Stevenson JC, Crook D, Godsland IF. Influence of age and menopause on serum lipids and lipoproteins in healthy women. Atherosclerosis. 1993;98:83-90.
    • (1993) Atherosclerosis , vol.98 , pp. 83-90
    • Stevenson, J.C.1    Crook, D.2    Godsland, I.F.3
  • 6
    • 84857508749 scopus 로고    scopus 로고
    • The 2012 hormone therapy position statement of: The North American Menopause Society
    • North American Menopause Society. The 2012 hormone therapy position statement of: The North American Menopause Society. Menopause. 2012;19:257-271.
    • (2012) Menopause , vol.19 , pp. 257-271
    • North American Menopause Society1
  • 7
    • 0034950083 scopus 로고    scopus 로고
    • Effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate on plasma lipids and lipoproteins, coagulation factors, and carbohydrate metabolism
    • Lobo RA, Bush T, Carr BR, Pickar JH. Effects of lower doses of conjugated equine estrogens and medroxyprogesterone acetate on plasma lipids and lipoproteins, coagulation factors, and carbohydrate metabolism. Fertil Steril. 2001;76:13-24.
    • (2001) Fertil Steril , vol.76 , pp. 13-24
    • Lobo, R.A.1    Bush, T.2    Carr, B.R.3    Pickar, J.H.4
  • 8
    • 0037125379 scopus 로고    scopus 로고
    • Risks and benefits of estrogen plus progestin in healthy postmenopausal women: Principal results from the Women's Health Initiative randomized controlled trial
    • Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results From the Women's Health Initiative randomized controlled trial. JAMA. 2002;288:321-333.
    • (2002) JAMA , vol.288 , pp. 321-333
    • Rossouw, J.E.1    Anderson, G.L.2    Prentice, R.L.3
  • 9
    • 1842867053 scopus 로고    scopus 로고
    • Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: The Women's Health Initiative randomized controlled trial
    • Anderson GL, Limacher M, Assaf AR, et al. Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial. JAMA. 2004;291:1701-1712.
    • (2004) JAMA , vol.291 , pp. 1701-1712
    • Anderson, G.L.1    Limacher, M.2    Assaf, A.R.3
  • 10
    • 33646271366 scopus 로고    scopus 로고
    • Brief report: Coronary heart disease events associated with hormone therapy in younger and older women. A meta-analysis
    • Salpeter SR, Walsh JM, Greyber E, Salpeter EE. Brief report: Coronary heart disease events associated with hormone therapy in younger and older women. A meta-analysis. J Gen Intern Med. 2006;21:363-366.
    • (2006) J Gen Intern Med , vol.21 , pp. 363-366
    • Salpeter, S.R.1    Walsh, J.M.2    Greyber, E.3    Salpeter, E.E.4
  • 11
    • 71149117152 scopus 로고    scopus 로고
    • Bayesian meta-analysis of hormone therapy and mortality in younger postmenopausal women
    • Salpeter SR, Cheng J, Thabane L, Buckley NS, Salpeter EE. Bayesian meta-analysis of hormone therapy and mortality in younger postmenopausal women. Am J Med. 2009;122:1016-1022.e1.
    • (2009) Am J Med , vol.122 , pp. 1016.e1-1022.e1
    • Salpeter, S.R.1    Cheng, J.2    Thabane, L.3    Buckley, N.S.4    Salpeter, E.E.5
  • 12
    • 84868307415 scopus 로고    scopus 로고
    • Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: Randomised trial
    • Schierbeck LL, Rejnmark L, Tofteng CL, et al. Effect of hormone replacement therapy on cardiovascular events in recently postmenopausal women: randomised trial. BMJ. 2012;345:e6409.
    • (2012) BMJ , vol.345
    • Schierbeck, L.L.1    Rejnmark, L.2    Tofteng, C.L.3
  • 13
    • 34047237367 scopus 로고    scopus 로고
    • Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause
    • Rossouw JE, Prentice RL, Manson JE, et al. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA. 2007;297:1465-1477.
    • (2007) JAMA , vol.297 , pp. 1465-1477
    • Rossouw, J.E.1    Prentice, R.L.2    Manson, J.E.3
  • 14
    • 84884917272 scopus 로고    scopus 로고
    • Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the women's health initiative randomized trials
    • Manson JE, Chlebowski RT, Stefanick ML, et al. Menopausal hormone therapy and health outcomes during the intervention and extended poststopping phases of the women's health initiative randomized trials. JAMA. 2013;310:1353-1368.
    • (2013) JAMA , vol.310 , pp. 1353-1368
    • Manson, J.E.1    Chlebowski, R.T.2    Stefanick, M.L.3
  • 16
    • 84902487684 scopus 로고    scopus 로고
    • Philadelphia, PA: Wyeth Pharmaceuticals Inc, a subsidiary of Pfizer Inc.
    • Duavee [package insert]. Philadelphia, PA: Wyeth Pharmaceuticals Inc, a subsidiary of Pfizer Inc.; 2013.
    • (2013) Duavee [Package Insert]
  • 18
    • 69049112720 scopus 로고    scopus 로고
    • Bazedoxifene/conjugated estrogens (BZA/CE): Incidence of uterine bleeding in postmenopausal women
    • Archer DF, Lewis V, Carr BR, Olivier S, Pickar JH. Bazedoxifene/conjugated estrogens (BZA/CE): incidence of uterine bleeding in postmenopausal women. Fertil Steril. 2009;92:1039-1044.
    • (2009) Fertil Steril , vol.92 , pp. 1039-1044
    • Archer, D.F.1    Lewis, V.2    Carr, B.R.3    Olivier, S.4    Pickar, J.H.5
  • 19
    • 77249172217 scopus 로고    scopus 로고
    • Effects of bazedoxifene/conjugated estrogens on quality of life in postmenopausal women with symptoms of vulvar/vaginal atrophy
    • Bachmann G, Bobula J, Mirkin S. Effects of bazedoxifene/conjugated estrogens on quality of life in postmenopausal women with symptoms of vulvar/vaginal atrophy. Climacteric. 2010;13:132-140.
    • (2010) Climacteric , vol.13 , pp. 132-140
    • Bachmann, G.1    Bobula, J.2    Mirkin, S.3
  • 20
    • 77949370016 scopus 로고    scopus 로고
    • A randomized, placebo- and active-controlled trial of bazedoxifene/conjugated estrogens for treatment of moderate to severe vulvar/vaginal atrophy in postmenopausal women
    • Kagan R, Williams RS, Pan K, Mirkin S, Pickar JH. A randomized, placebo- and active-controlled trial of bazedoxifene/conjugated estrogens for treatment of moderate to severe vulvar/vaginal atrophy in postmenopausal women. Menopause. 2010;17:281-289.
    • (2010) Menopause , vol.17 , pp. 281-289
    • Kagan, R.1    Williams, R.S.2    Pan, K.3    Mirkin, S.4    Pickar, J.H.5
  • 21
    • 69049083661 scopus 로고    scopus 로고
    • Efficacy of tissue-selective estrogen complex of bazedoxifene/conjugated estrogens for osteoporosis prevention in at-risk postmenopausal women
    • Lindsay R, Gallagher JC, Kagan R, Pickar JH, Constantine G. Efficacy of tissue-selective estrogen complex of bazedoxifene/conjugated estrogens for osteoporosis prevention in at-risk postmenopausal women. Fertil Steril. 2009;92:1045-1052.
    • (2009) Fertil Steril , vol.92 , pp. 1045-1052
    • Lindsay, R.1    Gallagher, J.C.2    Kagan, R.3    Pickar, J.H.4    Constantine, G.5
  • 22
    • 69049120132 scopus 로고    scopus 로고
    • Evaluation of bazedoxifene/conjugated estrogens for the treatment of menopausal symptoms and effects on metabolic parameters and overall safety profile
    • Lobo RA, Pinkerton JV, Gass ML, et al. Evaluation of bazedoxifene/conjugated estrogens for the treatment of menopausal symptoms and effects on metabolic parameters and overall safety profile. Fertil Steril. 2009;92:1025-1038.
    • (2009) Fertil Steril , vol.92 , pp. 1025-1038
    • Lobo, R.A.1    Pinkerton, J.V.2    Gass, M.L.3
  • 23
    • 69049085452 scopus 로고    scopus 로고
    • Endometrial effects of a tissue selective estrogen complex containing bazedoxifene/conjugated estrogens as a menopausal therapy
    • Pickar JH, Yeh IT, Bachmann G, Speroff L. Endometrial effects of a tissue selective estrogen complex containing bazedoxifene/conjugated estrogens as a menopausal therapy. Fertil Steril. 2009;92:1018-1024.
    • (2009) Fertil Steril , vol.92 , pp. 1018-1024
    • Pickar, J.H.1    Yeh, I.T.2    Bachmann, G.3    Speroff, L.4
  • 24
    • 68349129906 scopus 로고    scopus 로고
    • Relief of vasomotor symptoms with the tissue-selective estrogen complex containing bazedoxifene/conjugated estrogens: A randomized, controlled trial
    • Pinkerton JV, Utian WH, Constantine GD, Olivier S, Pickar JH. Relief of vasomotor symptoms with the tissue-selective estrogen complex containing bazedoxifene/conjugated estrogens: a randomized, controlled trial. Menopause. 2009;16:1116-1124.
    • (2009) Menopause , vol.16 , pp. 1116-1124
    • Pinkerton, J.V.1    Utian, W.H.2    Constantine, G.D.3    Olivier, S.4    Pickar, J.H.5
  • 25
    • 68149132588 scopus 로고    scopus 로고
    • Bazedoxifene/conjugated estrogens and quality of life in postmenopausal women
    • Utian W, Yu H, Bobula J, Mirkin S, Olivier S, Pickar JH. Bazedoxifene/conjugated estrogens and quality of life in postmenopausal women. Maturitas. 2009;63:329-335.
    • (2009) Maturitas , vol.63 , pp. 329-335
    • Utian, W.1    Yu, H.2    Bobula, J.3    Mirkin, S.4    Olivier, S.5    Pickar, J.H.6
  • 26
    • 84875503848 scopus 로고    scopus 로고
    • Effects of bazedoxifene/conjugated estrogens on endometrial safety and bone in postmenopausal women
    • Mirkin S, Komm BS, Pan K, Chines AA. Effects of bazedoxifene/conjugated estrogens on endometrial safety and bone in postmenopausal women. Climacteric. 2013;16:338-346.
    • (2013) Climacteric , vol.16 , pp. 338-346
    • Mirkin, S.1    Komm, B.S.2    Pan, K.3    Chines, A.A.4
  • 27
    • 84879078406 scopus 로고    scopus 로고
    • Breast effects of bazedoxifeneconjugated estrogens: A randomized controlled trial
    • Pinkerton JV, Harvey JA, Pan K, et al. Breast effects of bazedoxifeneconjugated estrogens: a randomized controlled trial. Obstet Gynecol. 2013;121:959-968.
    • (2013) Obstet Gynecol , vol.121 , pp. 959-968
    • Pinkerton, J.V.1    Harvey, J.A.2    Pan, K.3
  • 28
    • 84873407467 scopus 로고    scopus 로고
    • Breast density changes in a randomized controlled trial evaluating bazedoxifene/conjugated estrogens
    • Harvey JA, Pinkerton JV, Baracat EC, Shi H, Chines AA, Mirkin S. Breast density changes in a randomized controlled trial evaluating bazedoxifene/conjugated estrogens. Menopause. 2013;20:138-145.
    • (2013) Menopause , vol.20 , pp. 138-145
    • Harvey, J.A.1    Pinkerton, J.V.2    Baracat, E.C.3    Shi, H.4    Chines, A.A.5    Mirkin, S.6
  • 29
    • 84896703766 scopus 로고    scopus 로고
    • Sleep parameters and healthrelated quality of life with bazedoxifene/conjugated estrogens: A randomized trial
    • Pinkerton JV, Pan K, Abraham L, et al. Sleep parameters and healthrelated quality of life with bazedoxifene/conjugated estrogens: a randomized trial. Menopause. 2014;21:252-259.
    • (2014) Menopause , vol.21 , pp. 252-259
    • Pinkerton, J.V.1    Pan, K.2    Abraham, L.3
  • 31
    • 0037126526 scopus 로고    scopus 로고
    • Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report
    • National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation 2002;106:3143-3421.
    • (2002) Circulation , vol.106 , pp. 3143-3421
    • National Cholesterol Education Program (NCEP)1
  • 32
    • 0029823229 scopus 로고    scopus 로고
    • Metabolic effects of the menopause and oestrogen replacement
    • Stevenson JC. Metabolic effects of the menopause and oestrogen replacement. Baillieres Clin Obstet Gynaecol. 1996;10:449-467.
    • (1996) Baillieres Clin Obstet Gynaecol , vol.10 , pp. 449-467
    • Stevenson, J.C.1
  • 33
    • 0032567990 scopus 로고    scopus 로고
    • Hypertriglyceridemia as a cardiovascular risk factor
    • Austin MA, Hokanson JE, Edwards KL. Hypertriglyceridemia as a cardiovascular risk factor. Am J Cardiol 1998;81:7B-12B.
    • (1998) Am J Cardiol , vol.81 , pp. 7B-12B
    • Austin, M.A.1    Hokanson, J.E.2    Edwards, K.L.3
  • 34
    • 56549102911 scopus 로고    scopus 로고
    • The pairing of a selective estrogen receptor modulator, bazedoxifene, with conjugated estrogens as a new paradigm for the treatment of menopausal symptoms and osteoporosis prevention
    • Kharode Y, Bodine PV, Miller CP, Lyttle CR, Komm BS. The pairing of a selective estrogen receptor modulator, bazedoxifene, with conjugated estrogens as a new paradigm for the treatment of menopausal symptoms and osteoporosis prevention. Endocrinology. 2008;149:6084-6091.
    • (2008) Endocrinology , vol.149 , pp. 6084-6091
    • Kharode, Y.1    Bodine, P.V.2    Miller, C.P.3    Lyttle, C.R.4    Komm, B.S.5
  • 36
  • 37
    • 0020463159 scopus 로고
    • High density lipoprotein-2 and hepatic lipase: Reciprocal changes produced by estrogen and norgestrel
    • Tikkanen MJ, Nikkilä EA, Kuusi T, Sipinen SU. High density lipoprotein-2 and hepatic lipase: reciprocal changes produced by estrogen and norgestrel. J Clin Endocrinol Metab. 1982;54:1113-1117.
    • (1982) J Clin Endocrinol Metab , vol.54 , pp. 1113-1117
    • Tikkanen, M.J.1    Nikkilä, E.A.2    Kuusi, T.3    Sipinen, S.U.4
  • 38
    • 0028048487 scopus 로고
    • Impact of hormone replacement therapy on postprandial lipoproteins and lipoprotein(a) in normolipidemic postmenopausal women
    • Julius U, Fritsch H, Fritsch W, et al. Impact of hormone replacement therapy on postprandial lipoproteins and lipoprotein(a) in normolipidemic postmenopausal women. Clin Investig. 1994;72:502-507.
    • (1994) Clin Investig , vol.72 , pp. 502-507
    • Julius, U.1    Fritsch, H.2    Fritsch, W.3
  • 39
    • 0032547326 scopus 로고    scopus 로고
    • Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group
    • Hulley S, Grady D, Bush T, et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA. 1998;280:605-613.
    • (1998) JAMA , vol.280 , pp. 605-613
    • Hulley, S.1    Grady, D.2    Bush, T.3
  • 41
    • 13544275663 scopus 로고    scopus 로고
    • Rationale for using apolipoprotein B and apolipoprotein A-I as indicators of cardiac risk and as targets for lipid-lowering therapy
    • Walldius G, Jungner I. Rationale for using apolipoprotein B and apolipoprotein A-I as indicators of cardiac risk and as targets for lipid-lowering therapy. Eur Heart J. 2005;26:210-212.
    • (2005) Eur Heart J , vol.26 , pp. 210-212
    • Walldius, G.1    Jungner, I.2
  • 42
    • 0035894648 scopus 로고    scopus 로고
    • High apolipoprotein B, low apolipoprotein A-I, and improvement in the prediction of fatal myocardial infarction (AMORIS study): A prospective study
    • Walldius G, Jungner I, Holme I, Aastveit AH, Kolar W, Steiner E. High apolipoprotein B, low apolipoprotein A-I, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study. Lancet. 2001;358:2026-2033.
    • (2001) Lancet , vol.358 , pp. 2026-2033
    • Walldius, G.1    Jungner, I.2    Holme, I.3    Aastveit, A.H.4    Kolar, W.5    Steiner, E.6
  • 43
    • 84865120887 scopus 로고    scopus 로고
    • Lipoprotein(a) as a potential causal genetic risk factor of cardiovascular disease: A rationale for increased efforts to understand its pathophysiology and develop targeted therapies
    • Tsimikas S, Hall JL. Lipoprotein(a) as a potential causal genetic risk factor of cardiovascular disease: a rationale for increased efforts to understand its pathophysiology and develop targeted therapies. J Am Coll Cardiol 2012;60:716-721.
    • (2012) J Am Coll Cardiol , vol.60 , pp. 716-721
    • Tsimikas, S.1    Hall, J.L.2
  • 44
    • 84924225664 scopus 로고    scopus 로고
    • Cardiovascular safety of conjugated estrogens plus bazedoxifene: Meta-analysis of the SMART trials
    • published online ahead of print November 12, 2014
    • Komm BS, Thompson JR, Mirkin S. Cardiovascular safety of conjugated estrogens plus bazedoxifene: meta-analysis of the SMART trials [published online ahead of print November 12, 2014]. Climacteric. doi: 10.3109/13697137.2014.992011.
    • Climacteric
    • Komm, B.S.1    Thompson, J.R.2    Mirkin, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.