-
1
-
-
77951653074
-
Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis
-
Nair H, Nokes DJ, Gessner BD et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet 2010; 375:1545-1555.
-
(2010)
Lancet
, vol.375
, pp. 1545-1555
-
-
Nair, H.1
Nokes, D.J.2
Gessner, B.D.3
-
3
-
-
84863740703
-
Respiratory syncytial virus assembles into structured filamentous virion particles independently of host cytoskeleton and related proteins
-
Shaikh FY, Utley TJ, Craven RE et al. Respiratory syncytial virus assembles into structured filamentous virion particles independently of host cytoskeleton and related proteins. PLoS One 2012; 7:e40826.
-
(2012)
PLoS One
, vol.7
-
-
Shaikh, F.Y.1
Utley, T.J.2
Craven, R.E.3
-
4
-
-
82755189828
-
Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis
-
Nair H, Brooks WA, Katz M et al. Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis. Lancet 2011; 378:1917-1930.
-
(2011)
Lancet
, vol.378
, pp. 1917-1930
-
-
Nair, H.1
Brooks, W.A.2
Katz, M.3
-
5
-
-
84870516570
-
Mechanisms of respiratory syncytial virus modulation of airway immune responses
-
Lotz MT, Peebles RS. Mechanisms of respiratory syncytial virus modulation of airway immune responses. Curr Allergy Asthma Rep 2012; 12:380-387.
-
(2012)
Curr Allergy Asthma Rep
, vol.12
, pp. 380-387
-
-
Lotz, M.T.1
Peebles, R.S.2
-
6
-
-
84871735103
-
Viral and bacterial causes of severe acute respiratory illness among children aged less than 5 years in a high malaria prevalence area of western Kenya, 2007-2010
-
Feikin DR, Njenga MK, Bigogo G et al. Viral and bacterial causes of severe acute respiratory illness among children aged less than 5 years in a high malaria prevalence area of western Kenya, 2007-2010. Pediatr Infect Dis J 2013; 32:e14-e19.
-
(2013)
Pediatr Infect Dis J
, vol.32
, pp. e14-e19
-
-
Feikin, D.R.1
Njenga, M.K.2
Bigogo, G.3
-
7
-
-
28344445571
-
Rates of hospitalisation for influenza, respiratory syncytial virus and human metapneumovirus among infants and young children
-
Nicholson KG, McNally T, Silverman M, Simons P, Stockton JD, Zambon MC. Rates of hospitalisation for influenza, respiratory syncytial virus and human metapneumovirus among infants and young children. Vaccine 2006; 24:102-108.
-
(2006)
Vaccine
, vol.24
, pp. 102-108
-
-
Nicholson, K.G.1
McNally, T.2
Silverman, M.3
Simons, P.4
Stockton, J.D.5
Zambon, M.C.6
-
8
-
-
84903516044
-
Modelling the seasonal epidemics of respiratory syncytial virus in young children
-
Moore HC, Jacoby P, Hogan AB, Blyth CC, Mercer GN. Modelling the seasonal epidemics of respiratory syncytial virus in young children. PLoS One 2014; 9:e100422.
-
(2014)
PLoS One
, vol.9
-
-
Moore, H.C.1
Jacoby, P.2
Hogan, A.B.3
Blyth, C.C.4
Mercer, G.N.5
-
9
-
-
84893724739
-
Recent advances in diagnosis, prevention, and treatment of human respiratory syncytial virus
-
Bawage SS, Tiwari PM, Pillai S, Dennis V, Singh SR. Recent advances in diagnosis, prevention, and treatment of human respiratory syncytial virus. Adv Virol 2013; 2013:595768.
-
(2013)
Adv Virol
, vol.2013
, pp. 595768
-
-
Bawage, S.S.1
Tiwari, P.M.2
Pillai, S.3
Dennis, V.4
Singh, S.R.5
-
10
-
-
0036254559
-
The pathogenesis of respiratory syncytial virus disease in childhood
-
McNamara PS, Smyth RL. The pathogenesis of respiratory syncytial virus disease in childhood. Br Med Bull 2002; 61:13-28.
-
(2002)
Br Med Bull
, vol.61
, pp. 13-28
-
-
McNamara, P.S.1
Smyth, R.L.2
-
11
-
-
0022589560
-
Respiratory syncytial viral infection in children with compromised immune function
-
Hall CB, Powell KR, MacDonald NE et al. Respiratory syncytial viral infection in children with compromised immune function. N Engl J Med 1986; 315:77-81.
-
(1986)
N Engl J Med
, vol.315
, pp. 77-81
-
-
Hall, C.B.1
Powell, K.R.2
MacDonald, N.E.3
-
12
-
-
79954567948
-
An evaluation of the emerging interventions against Respiratory Syncytial Virus (RSV)-associated acute lower respiratory infections in children
-
Nair H, Verma VR, Theodoratou E et al. An evaluation of the emerging interventions against Respiratory Syncytial Virus (RSV)-associated acute lower respiratory infections in children. BMC Public Health 2011; 11(Suppl 3):S30.
-
(2011)
BMC Public Health
, vol.11
, Issue.Suppl 3
-
-
Nair, H.1
Verma, V.R.2
Theodoratou, E.3
-
13
-
-
84925884845
-
Risks and prevention of severe RS virus infection among children with immunodeficiency and Down's syndrome
-
Mori M, Morio T, Ito S et al. Risks and prevention of severe RS virus infection among children with immunodeficiency and Down's syndrome. J Infect Chemother 2014; 20:455-459.
-
(2014)
J Infect Chemother
, vol.20
, pp. 455-459
-
-
Mori, M.1
Morio, T.2
Ito, S.3
-
16
-
-
84891921055
-
Glucocorticoids for acute viral bronchiolitis in infants and young children
-
Fernandes RM, Hartling L. Glucocorticoids for acute viral bronchiolitis in infants and young children. JAMA 2014; 311:87-88.
-
(2014)
JAMA
, vol.311
, pp. 87-88
-
-
Fernandes, R.M.1
Hartling, L.2
-
17
-
-
84930797051
-
-
(Cited 1 February 2015).
-
ICTRP Search Portal [Internet]. Available at http://apps.who.int/trialsearch/Default.aspx (Cited 1 February 2015).
-
-
-
-
18
-
-
84930817570
-
-
(Cited 1 February 2015).
-
Home - PubMed - NCBI [Internet]. Available at http://www.ncbi.nlm.nih.gov/pubmed/ (Cited 1 February 2015).
-
-
-
-
19
-
-
37349028337
-
Respiratory syncytial virus (RSV) vaccines-two steps back for one leap forward
-
Power UF. Respiratory syncytial virus (RSV) vaccines-two steps back for one leap forward. J Clin Virol 2008; 41:38-44.
-
(2008)
J Clin Virol
, vol.41
, pp. 38-44
-
-
Power, U.F.1
-
20
-
-
84893499613
-
Progress and challenges in RSV prophylaxis and vaccine development
-
Haynes LM. Progress and challenges in RSV prophylaxis and vaccine development. J Infect Dis 2013; 208(Suppl):S177-S183.
-
(2013)
J Infect Dis
, vol.208
, Issue.Suppl
, pp. S177-S183
-
-
Haynes, L.M.1
-
21
-
-
0017283602
-
Respiratory syncytial virus infections within families
-
Hall CB, Geiman JM, Biggar R, Kotok DI, Hogan PM, Douglas GR. Respiratory syncytial virus infections within families. N Engl J Med 1976; 294:414-419.
-
(1976)
N Engl J Med
, vol.294
, pp. 414-419
-
-
Hall, C.B.1
Geiman, J.M.2
Biggar, R.3
Kotok, D.I.4
Hogan, P.M.5
Douglas, G.R.6
-
22
-
-
0018760287
-
Respiratory-syncytial-virus infections, reinfections and immunity. A prospective, longitudinal study in young children
-
Henderson FW, Collier AM, Clyde WA, Denny FW. Respiratory-syncytial-virus infections, reinfections and immunity. A prospective, longitudinal study in young children. N Engl J Med 1979; 300:530-534.
-
(1979)
N Engl J Med
, vol.300
, pp. 530-534
-
-
Henderson, F.W.1
Collier, A.M.2
Clyde, W.A.3
Denny, F.W.4
-
23
-
-
44949236320
-
The role of neutralizing antibodies in protection of American Indian infants against respiratory syncytial virus disease
-
Eick A, Karron R, Shaw J et al. The role of neutralizing antibodies in protection of American Indian infants against respiratory syncytial virus disease. Pediatr Infect Dis J 2008; 27:207-212.
-
(2008)
Pediatr Infect Dis J
, vol.27
, pp. 207-212
-
-
Eick, A.1
Karron, R.2
Shaw, J.3
-
24
-
-
0038384092
-
Correlates of immunity to respiratory syncytial virus (RSV) associated-hospitalization: establishment of minimum protective threshold levels of serum neutralizing antibodies
-
Piedra PA, Jewell AM, Cron SG, Atmar RL, Glezen WP. Correlates of immunity to respiratory syncytial virus (RSV) associated-hospitalization: establishment of minimum protective threshold levels of serum neutralizing antibodies. Vaccine 2003; 21:3479-3482.
-
(2003)
Vaccine
, vol.21
, pp. 3479-3482
-
-
Piedra, P.A.1
Jewell, A.M.2
Cron, S.G.3
Atmar, R.L.4
Glezen, W.P.5
-
25
-
-
0033791293
-
Evaluation of a live, cold-passaged, temperature-sensitive, respiratory syncytial virus vaccine candidate in infancy
-
Wright PF, Karron Ra, Belshe RB et al. Evaluation of a live, cold-passaged, temperature-sensitive, respiratory syncytial virus vaccine candidate in infancy. J Infect Dis 2000; 182:1331-1342.
-
(2000)
J Infect Dis
, vol.182
, pp. 1331-1342
-
-
Wright, P.F.1
Karron, R.2
Belshe, R.B.3
-
26
-
-
34748850172
-
The absence of enhanced disease with wild type respiratory syncytial virus infection occurring after receipt of live, attenuated, respiratory syncytial virus vaccines
-
Wright PF, Karron Ra, Belshe RB et al. The absence of enhanced disease with wild type respiratory syncytial virus infection occurring after receipt of live, attenuated, respiratory syncytial virus vaccines. Vaccine 2007; 25:7372-7378.
-
(2007)
Vaccine
, vol.25
, pp. 7372-7378
-
-
Wright, P.F.1
Karron, R.2
Belshe, R.B.3
-
27
-
-
0030657620
-
Evaluation of two live, cold-passaged, temperature-sensitive respiratory syncytial virus vaccines in chimpanzees and in human adults, infants, and children
-
Karron Ra, Wright PF, Crowe JE et al. Evaluation of two live, cold-passaged, temperature-sensitive respiratory syncytial virus vaccines in chimpanzees and in human adults, infants, and children. J Infect Dis 1997; 176:1428-1436.
-
(1997)
J Infect Dis
, vol.176
, pp. 1428-1436
-
-
Karron, R.1
Wright, P.F.2
Crowe, J.E.3
-
28
-
-
0015146196
-
Clinical and immunological response of infants and children to administration of low-temperature adapted respiratory syncytial virus
-
Kim HW, Arrobio JO, Pyles G et al. Clinical and immunological response of infants and children to administration of low-temperature adapted respiratory syncytial virus. Pediatrics 1971; 48:745-755.
-
(1971)
Pediatrics
, vol.48
, pp. 745-755
-
-
Kim, H.W.1
Arrobio, J.O.2
Pyles, G.3
-
29
-
-
84877261585
-
Attenuation of live respiratory syncytial virus vaccines is associated with reductions in levels of nasal cytokines
-
Karron RA, Thumar B, Schappell E, Buchholz UJ, Collins PL. Attenuation of live respiratory syncytial virus vaccines is associated with reductions in levels of nasal cytokines. J Infect Dis 2013; 207:1773-1779.
-
(2013)
J Infect Dis
, vol.207
, pp. 1773-1779
-
-
Karron, R.A.1
Thumar, B.2
Schappell, E.3
Buchholz, U.J.4
Collins, P.L.5
-
30
-
-
32044433987
-
The interferon antagonist NS2 protein of respiratory syncytial virus is an important virulence determinant for humans
-
Wright PF, Karron Ra, Madhi Sa et al. The interferon antagonist NS2 protein of respiratory syncytial virus is an important virulence determinant for humans. J Infect Dis 2006; 193:573-581.
-
(2006)
J Infect Dis
, vol.193
, pp. 573-581
-
-
Wright, P.F.1
Karron, R.2
Madhi, S.3
-
31
-
-
20144370691
-
Identification of a recombinant live attenuated respiratory syncytial virus vaccine candidate that is highly attenuated in infants
-
Karron Ra, Wright PF, Belshe RB et al. Identification of a recombinant live attenuated respiratory syncytial virus vaccine candidate that is highly attenuated in infants. J Infect Dis 2005; 191:1093-1104.
-
(2005)
J Infect Dis
, vol.191
, pp. 1093-1104
-
-
Karron, R.1
Wright, P.F.2
Belshe, R.B.3
-
32
-
-
84908434444
-
Refining the balance of attenuation and immunogenicity of respiratory syncytial virus by targeted codon deoptimization of virulence genes
-
Meng J, Lee S, Hotard AL, Moore ML. Refining the balance of attenuation and immunogenicity of respiratory syncytial virus by targeted codon deoptimization of virulence genes. MBio 2014; 5:e01704-e01714.
-
(2014)
MBio
, vol.5
, pp. e01704-e01714
-
-
Meng, J.1
Lee, S.2
Hotard, A.L.3
Moore, M.L.4
-
33
-
-
84873744697
-
Respiratory syncytial virus modified by deletions of the NS2 gene and amino acid S1313 of the L polymerase protein is a temperature-sensitive, live-attenuated vaccine candidate that is phenotypically stable at physiological temperature
-
Luongo C, Winter CC, Collins PL, Buchholz UJ. Respiratory syncytial virus modified by deletions of the NS2 gene and amino acid S1313 of the L polymerase protein is a temperature-sensitive, live-attenuated vaccine candidate that is phenotypically stable at physiological temperature. J Virol 2013; 87:1985-1996.
-
(2013)
J Virol
, vol.87
, pp. 1985-1996
-
-
Luongo, C.1
Winter, C.C.2
Collins, P.L.3
Buchholz, U.J.4
-
34
-
-
84894048036
-
Safety and immunogenicity of a live attenuated RSV vaccine in healthy RSV-seronegative children 5 to 24 months of age
-
Malkin E, Yogev R, Abughali N et al. Safety and immunogenicity of a live attenuated RSV vaccine in healthy RSV-seronegative children 5 to 24 months of age. PLoS One 2013; 8:e77104.
-
(2013)
PLoS One
, vol.8
-
-
Malkin, E.1
Yogev, R.2
Abughali, N.3
-
35
-
-
84930814940
-
-
IMPAACT P1114 (DAIDS ID 11948) A Phase I Study of the Safety and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine RSV cps2, Lot RSV # 005A, Delivered as Nose Drops to RSV-Seronegative Infants and Children 6 to 24 Mon. Available at(accessed 01 February 2015)
-
IMPAACT P1114 (DAIDS ID 11948) A Phase I Study of the Safety and Immunogenicity of a Single Dose of the Recombinant Live-Attenuated Respiratory Syncytial Virus Vaccine RSV cps2, Lot RSV # 005A, Delivered as Nose Drops to RSV-Seronegative Infants and Children 6 to 24 Mon. 2014 Available at http://impaactnetwork.org/studies/P1114.asp (accessed 01 February 2015)
-
(2014)
-
-
-
36
-
-
0033613202
-
The M2-2 protein of human respiratory syncytial virus is a regulatory factor involved in the balance between RNA replication and transcription
-
Bermingham a, Collins PL. The M2-2 protein of human respiratory syncytial virus is a regulatory factor involved in the balance between RNA replication and transcription. Proc Natl Acad Sci U S A 1999; 96:11259-11264.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11259-11264
-
-
Bermingham, A.1
Collins, P.L.2
-
37
-
-
0141566351
-
Effects of human metapneumovirus and respiratory syncytial virus antigen insertion in two 3' proximal genome positions of bovine/human parainfluenza virus type 3 on virus replication and immunogenicity
-
Tang RS, Schickli JH, MacPhail M et al. Effects of human metapneumovirus and respiratory syncytial virus antigen insertion in two 3' proximal genome positions of bovine/human parainfluenza virus type 3 on virus replication and immunogenicity. J Virol 2003; 77:10819-10828.
-
(2003)
J Virol
, vol.77
, pp. 10819-10828
-
-
Tang, R.S.1
Schickli, J.H.2
MacPhail, M.3
-
38
-
-
0035859824
-
Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion
-
González-Reyes L, Ruiz-Argüello MB, García-Barreno B et al. Cleavage of the human respiratory syncytial virus fusion protein at two distinct sites is required for activation of membrane fusion. Proc Natl Acad Sci U S A 2001; 98:9859-9864.
-
(2001)
Proc Natl Acad Sci U S A
, vol.98
, pp. 9859-9864
-
-
González-Reyes, L.1
Ruiz-Argüello, M.B.2
García-Barreno, B.3
-
39
-
-
84858158220
-
Phase 1 study of the safety and immunogenicity of a live, attenuated respiratory syncytial virus and parainfluenza virus type 3 vaccine in seronegative children
-
Bernstein DI, Malkin E, Abughali N, Falloon J, Yi T, Dubovsky F. Phase 1 study of the safety and immunogenicity of a live, attenuated respiratory syncytial virus and parainfluenza virus type 3 vaccine in seronegative children. Pediatr Infect Dis J 2012; 31:109-114.
-
(2012)
Pediatr Infect Dis J
, vol.31
, pp. 109-114
-
-
Bernstein, D.I.1
Malkin, E.2
Abughali, N.3
Falloon, J.4
Yi, T.5
Dubovsky, F.6
-
40
-
-
84878393878
-
Implication of respiratory syncytial virus (RSV) F transgene sequence heterogeneity observed in Phase 1 evaluation of MEDI-534, a live attenuated parainfluenza type 3 vectored RSV vaccine
-
Yang C-F, Wang CK, Malkin E et al. Implication of respiratory syncytial virus (RSV) F transgene sequence heterogeneity observed in Phase 1 evaluation of MEDI-534, a live attenuated parainfluenza type 3 vectored RSV vaccine. Vaccine 2013; 31:2822-2827.
-
(2013)
Vaccine
, vol.31
, pp. 2822-2827
-
-
Yang, C.-F.1
Wang, C.K.2
Malkin, E.3
-
41
-
-
84871661160
-
Safety and immunogenicity of a Sf9 insect cell-derived respiratory syncytial virus fusion protein nanoparticle vaccine
-
Glenn GM, Smith G, Fries L et al. Safety and immunogenicity of a Sf9 insect cell-derived respiratory syncytial virus fusion protein nanoparticle vaccine. Vaccine 2013; 31:524-532.
-
(2013)
Vaccine
, vol.31
, pp. 524-532
-
-
Glenn, G.M.1
Smith, G.2
Fries, L.3
-
42
-
-
84870659737
-
Respiratory syncytial virus fusion glycoprotein expressed in insect cells form protein nanoparticles that induce protective immunity in cotton rats
-
Smith G, Raghunandan R, Wu Y et al. Respiratory syncytial virus fusion glycoprotein expressed in insect cells form protein nanoparticles that induce protective immunity in cotton rats. PLoS One 2012; 7:e50852.
-
(2012)
PLoS One
, vol.7
-
-
Smith, G.1
Raghunandan, R.2
Wu, Y.3
-
43
-
-
84930816480
-
Recombinant nanoparticle RSV F vaccine for respiratory syncytial virus: preclinical efficacy and clinical safety and immunogenicity
-
(accessed 01 February 2015).
-
Glenn G, Raghunandan R, Lu H, Zhou B, Ngai K. Recombinant nanoparticle RSV F vaccine for respiratory syncytial virus: preclinical efficacy and clinical safety and immunogenicity. 2011. Available at https://www.novavax.com/download/file/presentations/RSV-F-Phase-1-Poster-2011_gs.pdf (accessed 01 February 2015).
-
(2011)
-
-
Glenn, G.1
Raghunandan, R.2
Lu, H.3
Zhou, B.4
Ngai, K.5
-
44
-
-
78149457931
-
A synthetic adjuvant to enhance and expand immune responses to influenza vaccines
-
Coler RN, Baldwin SL, Shaverdian N et al. A synthetic adjuvant to enhance and expand immune responses to influenza vaccines. PLoS One 2010; 5:e13677.
-
(2010)
PLoS One
, vol.5
-
-
Coler, R.N.1
Baldwin, S.L.2
Shaverdian, N.3
-
45
-
-
79959338198
-
Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers
-
Swanson Ka, Settembre EC, Shaw Ca et al. Structural basis for immunization with postfusion respiratory syncytial virus fusion F glycoprotein (RSV F) to elicit high neutralizing antibody titers. Proc Natl Acad Sci U S A 2011; 108:9619-9624.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 9619-9624
-
-
Swanson, K.1
Settembre, E.C.2
Shaw, C.3
-
46
-
-
84887277978
-
Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus
-
McLellan JS, Chen M, Joyce MG et al. Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus. Science 2013; 342:592-598.
-
(2013)
Science
, vol.342
, pp. 592-598
-
-
McLellan, J.S.1
Chen, M.2
Joyce, M.G.3
-
47
-
-
84857410882
-
Neutralizing antibodies against the preactive form of respiratory syncytial virus fusion protein offer unique possibilities for clinical intervention
-
Magro M, Mas V, Chappell K et al. Neutralizing antibodies against the preactive form of respiratory syncytial virus fusion protein offer unique possibilities for clinical intervention. Proc Natl Acad Sci 2012; 109:3089-3094.
-
(2012)
Proc Natl Acad Sci
, vol.109
, pp. 3089-3094
-
-
Magro, M.1
Mas, V.2
Chappell, K.3
-
49
-
-
70349275249
-
Respiratory syncytial virus nonstructural proteins decrease levels of multiple members of the cellular interferon pathways
-
Swedan S, Musiyenko A, Barik S. Respiratory syncytial virus nonstructural proteins decrease levels of multiple members of the cellular interferon pathways. J Virol 2009; 83:9682-9693.
-
(2009)
J Virol
, vol.83
, pp. 9682-9693
-
-
Swedan, S.1
Musiyenko, A.2
Barik, S.3
-
50
-
-
67049119148
-
Respiratory syncytial virus proteins modulate suppressors of cytokine signaling 1 and 3 and the type I interferon response to infection by a toll-like receptor pathway
-
Oshansky CM, Krunkosky TM, Barber J, Jones LP, Tripp RA. Respiratory syncytial virus proteins modulate suppressors of cytokine signaling 1 and 3 and the type I interferon response to infection by a toll-like receptor pathway. Viral Immunol 2009; 22:147-161.
-
(2009)
Viral Immunol
, vol.22
, pp. 147-161
-
-
Oshansky, C.M.1
Krunkosky, T.M.2
Barber, J.3
Jones, L.P.4
Tripp, R.A.5
-
51
-
-
0030275487
-
RespiGam: an RSV immune globulin
-
Oertel MD. RespiGam: an RSV immune globulin. Pediatr Nurs 1996; 22:525-528.
-
(1996)
Pediatr Nurs
, vol.22
, pp. 525-528
-
-
Oertel, M.D.1
-
52
-
-
64949096235
-
Immunoprophylaxis against respiratory syncytial virus (RSV) with palivizumab in children: a systematic review and economic evaluation
-
ix-x, 1-86.
-
Wang D, Cummins C, Bayliss S, Sandercock J, Burls A. Immunoprophylaxis against respiratory syncytial virus (RSV) with palivizumab in children: a systematic review and economic evaluation. Health Technol Assess 2008; 12:iii, ix-x, 1-86.
-
(2008)
Health Technol Assess
, vol.12
, pp. 3
-
-
Wang, D.1
Cummins, C.2
Bayliss, S.3
Sandercock, J.4
Burls, A.5
-
53
-
-
0026504783
-
Severe respiratory syncytial virus pneumonia after autologous bone marrow transplantation: a report of three cases and review
-
Fouillard L, Mouthon L, Laporte JP et al. Severe respiratory syncytial virus pneumonia after autologous bone marrow transplantation: a report of three cases and review. Bone Marrow Transplant 1992; 9:97-100.
-
(1992)
Bone Marrow Transplant
, vol.9
, pp. 97-100
-
-
Fouillard, L.1
Mouthon, L.2
Laporte, J.P.3
-
54
-
-
63849263058
-
Motavizumab, a second-generation humanized mAb for the prevention of respiratory syncytial virus infection in high-risk populations
-
Weisman LE. Motavizumab, a second-generation humanized mAb for the prevention of respiratory syncytial virus infection in high-risk populations. Curr Opin Mol Ther 2009; 11:208-218.
-
(2009)
Curr Opin Mol Ther
, vol.11
, pp. 208-218
-
-
Weisman, L.E.1
-
55
-
-
84902544617
-
Motavizumab treatment of infants hospitalized with respiratory syncytial virus infection does not decrease viral load or severity of illness
-
Ramilo O, Lagos R, Sáez-Llorens X et al. Motavizumab treatment of infants hospitalized with respiratory syncytial virus infection does not decrease viral load or severity of illness. Pediatr Infect Dis J 2014; 33:703-709.
-
(2014)
Pediatr Infect Dis J
, vol.33
, pp. 703-709
-
-
Ramilo, O.1
Lagos, R.2
Sáez-Llorens, X.3
-
56
-
-
73849116425
-
Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming
-
Kwakkenbos MJ, Diehl SA, Yasuda E et al. Generation of stable monoclonal antibody-producing B cell receptor-positive human memory B cells by genetic programming. Nat Med 2010; 16:123-128.
-
(2010)
Nat Med
, vol.16
, pp. 123-128
-
-
Kwakkenbos, M.J.1
Diehl, S.A.2
Yasuda, E.3
-
57
-
-
84887418713
-
A novel investigational Fc-modified humanized monoclonal antibody, motavizumab-YTE, has an extended half-life in healthy adults
-
Robbie GJ, Criste R, Dall'acqua WF et al. A novel investigational Fc-modified humanized monoclonal antibody, motavizumab-YTE, has an extended half-life in healthy adults. Antimicrob Agents Chemother 2013; 57:6147-6153.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 6147-6153
-
-
Robbie, G.J.1
Criste, R.2
Dall'acqua, W.F.3
-
58
-
-
84930813979
-
-
Human antibodies to respiratory syncytial virus f protein and methods of use thereof
-
Human antibodies to respiratory syncytial virus f protein and methods of use thereof. 2014. Patent number: US20140271653 A1.
-
(2014)
-
-
-
59
-
-
84880806823
-
Successful systemic high-dose ribavirin treatment of respiratory syncytial virus-induced infections occurring pre-engraftment in allogeneic hematopoietic stem cell transplant recipients
-
Gueller S, Duenzinger U, Wolf T et al. Successful systemic high-dose ribavirin treatment of respiratory syncytial virus-induced infections occurring pre-engraftment in allogeneic hematopoietic stem cell transplant recipients. Transpl Infect Dis 2013; 15:435-440.
-
(2013)
Transpl Infect Dis
, vol.15
, pp. 435-440
-
-
Gueller, S.1
Duenzinger, U.2
Wolf, T.3
-
60
-
-
84899632970
-
Respiratory syncytial virus: current and emerging treatment options
-
Turner TL, Kopp BT, Paul G, Landgrave LC, Hayes D, Thompson R. Respiratory syncytial virus: current and emerging treatment options. Clinicoecon Outcomes Res 2014; 6:217-225.
-
(2014)
Clinicoecon Outcomes Res
, vol.6
, pp. 217-225
-
-
Turner, T.L.1
Kopp, B.T.2
Paul, G.3
Landgrave, L.C.4
Hayes, D.5
Thompson, R.6
-
61
-
-
77950972810
-
Pharmacologic advances in the treatment and prevention of respiratory syncytial virus
-
Empey KM, Peebles RS, Kolls JK. Pharmacologic advances in the treatment and prevention of respiratory syncytial virus. Clin Infect Dis 2010; 50:1258-1267.
-
(2010)
Clin Infect Dis
, vol.50
, pp. 1258-1267
-
-
Empey, K.M.1
Peebles, R.S.2
Kolls, J.K.3
-
62
-
-
84923882231
-
Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study
-
Mackman RL, Sangi M, Sperandio D et al. Discovery of an oral respiratory syncytial virus (RSV) fusion inhibitor (GS-5806) and clinical proof of concept in a human RSV challenge study. J Med Chem 2015; 58:1630-1643.
-
(2015)
J Med Chem
, vol.58
, pp. 1630-1643
-
-
Mackman, R.L.1
Sangi, M.2
Sperandio, D.3
-
63
-
-
84907363348
-
Oral GS-5806 activity in a respiratory syncytial virus challenge study
-
DeVincenzo JP, Whitley RJ, Mackman RL et al. Oral GS-5806 activity in a respiratory syncytial virus challenge study. N Engl J Med 2014; 371:711-722.
-
(2014)
N Engl J Med
, vol.371
, pp. 711-722
-
-
DeVincenzo, J.P.1
Whitley, R.J.2
Mackman, R.L.3
-
64
-
-
84954215381
-
Emerging roles of interferon-stimulated genes in the innate immune response to hepatitis C virus infection
-
Wong M-T, Chen SS-L. Emerging roles of interferon-stimulated genes in the innate immune response to hepatitis C virus infection. Cell Mol Immunol 2014. doi: 10.1038/cmi.2014.127.
-
(2014)
Cell Mol Immunol
-
-
Wong, M.-T.1
Chen, S.-L.2
-
65
-
-
84921030166
-
Therapeutic potential of siRNA and DNAzymes in cancer
-
Karnati HK, Yalagala RS, Undi R, Pasupuleti SR, Gutti RK. Therapeutic potential of siRNA and DNAzymes in cancer. Tumour Biol 2014; 35:9505-9521.
-
(2014)
Tumour Biol
, vol.35
, pp. 9505-9521
-
-
Karnati, H.K.1
Yalagala, R.S.2
Undi, R.3
Pasupuleti, S.R.4
Gutti, R.K.5
-
66
-
-
84902482584
-
Nanoparticle-mediated systemic delivery of siRNA for treatment of cancers and viral infections
-
Draz MS, Fang BA, Zhang P et al. Nanoparticle-mediated systemic delivery of siRNA for treatment of cancers and viral infections. Theranostics 2014; 4:872-892.
-
(2014)
Theranostics
, vol.4
, pp. 872-892
-
-
Draz, M.S.1
Fang, B.A.2
Zhang, P.3
-
68
-
-
38749136602
-
Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV)
-
DeVincenzo J, Cehelsky JE, Alvarez R et al. Evaluation of the safety, tolerability and pharmacokinetics of ALN-RSV01, a novel RNAi antiviral therapeutic directed against respiratory syncytial virus (RSV). Antiviral Res 2008; 77:225-231.
-
(2008)
Antiviral Res
, vol.77
, pp. 225-231
-
-
DeVincenzo, J.1
Cehelsky, J.E.2
Alvarez, R.3
-
69
-
-
77952688315
-
A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus
-
DeVincenzo J, Lambkin-Williams R, Wilkinson T et al. A randomized, double-blind, placebo-controlled study of an RNAi-based therapy directed against respiratory syncytial virus. Proc Natl Acad Sci U S A 2010; 107:8800-8805.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 8800-8805
-
-
DeVincenzo, J.1
Lambkin-Williams, R.2
Wilkinson, T.3
-
70
-
-
79951849229
-
RNA interference therapy in lung transplant patients infected with respiratory syncytial virus
-
Zamora MR, Budev M, Rolfe M et al. RNA interference therapy in lung transplant patients infected with respiratory syncytial virus. Am J Respir Crit Care Med 2011; 183:531-538.
-
(2011)
Am J Respir Crit Care Med
, vol.183
, pp. 531-538
-
-
Zamora, M.R.1
Budev, M.2
Rolfe, M.3
-
71
-
-
84923892193
-
Treatment with Oral ALS-008176, a Nucleoside Analog, Rapidly Reduces RSV Viral Load and Clinical Disease Severity in a Healthy Volunteer Challenge Study.
-
IDWeek 2014. Idsa
-
Devincenzo J. Treatment with Oral ALS-008176, a Nucleoside Analog, Rapidly Reduces RSV Viral Load and Clinical Disease Severity in a Healthy Volunteer Challenge Study. IDWeek 2014. Idsa; 2014.
-
(2014)
-
-
Devincenzo, J.1
-
72
-
-
80053438410
-
RSV 2010: recent advances in research on respiratory syncytial virus and other pneumoviruses
-
Van Bleek GM, Osterhaus ADME, de Swart RL. RSV 2010: recent advances in research on respiratory syncytial virus and other pneumoviruses. Vaccine 2011; 29:7285-7291.
-
(2011)
Vaccine
, vol.29
, pp. 7285-7291
-
-
Van Bleek, G.M.1
Osterhaus, A.D.M.E.2
de Swart, R.L.3
-
73
-
-
79953654632
-
Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules
-
Hultberg A, Temperton NJ, Rosseels V et al. Llama-derived single domain antibodies to build multivalent, superpotent and broadened neutralizing anti-viral molecules. PLoS One 2011; 6:e17665.
-
(2011)
PLoS One
, vol.6
-
-
Hultberg, A.1
Temperton, N.J.2
Rosseels, V.3
-
75
-
-
84930786983
-
Delivery of ALX-0171 by inhalation greatly reduces disease burden in a neonatal lamb RSV infection model
-
9th RSV Symp, Stellenbosch
-
Detalle L. Delivery of ALX-0171 by inhalation greatly reduces disease burden in a neonatal lamb RSV infection model. 9th RSV Symp, Stellenbosch, 2014.
-
(2014)
-
-
Detalle, L.1
-
76
-
-
84902460865
-
Lamb model of respiratory syncytial virus-associated lung disease: insights to pathogenesis and novel treatments
-
Ackermann MR. Lamb model of respiratory syncytial virus-associated lung disease: insights to pathogenesis and novel treatments. ILAR J 2014; 55:4-15.
-
(2014)
ILAR J
, vol.55
, pp. 4-15
-
-
Ackermann, M.R.1
-
78
-
-
20444501870
-
Respiratory syncytial virus and neutrophil activation
-
Bataki EL, Evans GS, Everard ML. Respiratory syncytial virus and neutrophil activation. Clin Exp Immunol 2005; 140:470-477.
-
(2005)
Clin Exp Immunol
, vol.140
, pp. 470-477
-
-
Bataki, E.L.1
Evans, G.S.2
Everard, M.L.3
-
79
-
-
84893186080
-
The pharmacokinetics of conventional and bioenhanced tablet formulations of danirixin (GSK1325756) following oral administration in healthy, elderly, human volunteers
-
Miller BE, Smart K, Mistry S et al. The pharmacokinetics of conventional and bioenhanced tablet formulations of danirixin (GSK1325756) following oral administration in healthy, elderly, human volunteers. Eur J Drug Metab Pharmacokinet 2014; 39:173-181.
-
(2014)
Eur J Drug Metab Pharmacokinet
, vol.39
, pp. 173-181
-
-
Miller, B.E.1
Smart, K.2
Mistry, S.3
-
80
-
-
84930797706
-
RV568, a narrow spectrum kinase inhibitor (NSKI), inhibits virus induced nasal interleukin-8 (IL8) in the human viral challenge model where healthy adult male volunteers were experimentally inoculated with live respiratory syncytial virus [Internet]
-
(Cited 1 February 2015).
-
RV568, a narrow spectrum kinase inhibitor (NSKI), inhibits virus induced nasal interleukin-8 (IL8) in the human viral challenge model where healthy adult male volunteers were experimentally inoculated with live respiratory syncytial virus [Internet]. Available at http://erj.ersjournals.com/content/42/Suppl_57/1970.full.pdf (Cited 1 February 2015).
-
-
-
-
81
-
-
84930795164
-
Tolerability And Pharmacokinetic Profile Of RV568, A Narrow Spectrum Kinase Inhibitor, Following Single And Repeat Inhaled Dosing In Healthy Volunteers (ATS Journals)
-
American Thoracic Society International Conference Meetings Abstracts.
-
Cass L, Woodward K, Brindley C, Warrington S. Tolerability And Pharmacokinetic Profile Of RV568, A Narrow Spectrum Kinase Inhibitor, Following Single And Repeat Inhaled Dosing In Healthy Volunteers (ATS Journals). American Thoracic Society International Conference Meetings Abstracts.
-
-
-
Cass, L.1
Woodward, K.2
Brindley, C.3
Warrington, S.4
-
82
-
-
0036113489
-
Respiratory syncytial virus bronchiolitis: disease severity, interleukin-8, and virus genotype
-
Smyth RL, Mobbs KJ, O'Hea U, Ashby D, Hart CA. Respiratory syncytial virus bronchiolitis: disease severity, interleukin-8, and virus genotype. Pediatr Pulmonol 2002; 33:339-346.
-
(2002)
Pediatr Pulmonol
, vol.33
, pp. 339-346
-
-
Smyth, R.L.1
Mobbs, K.J.2
O'Hea, U.3
Ashby, D.4
Hart, C.A.5
-
83
-
-
18944399906
-
Respiratory syncytial virus load predicts disease severity in previously healthy infants
-
DeVincenzo JP, El Saleeby CM, Bush AJ. Respiratory syncytial virus load predicts disease severity in previously healthy infants. J Infect Dis 2005; 191:1861-1868.
-
(2005)
J Infect Dis
, vol.191
, pp. 1861-1868
-
-
DeVincenzo, J.P.1
El Saleeby, C.M.2
Bush, A.J.3
-
84
-
-
80052422367
-
Respiratory syncytial virus load, viral dynamics, and disease severity in previously healthy naturally infected children
-
El Saleeby CM, Bush AJ, Harrison LM, Aitken JA, Devincenzo JP. Respiratory syncytial virus load, viral dynamics, and disease severity in previously healthy naturally infected children. J Infect Dis 2011; 204:996-1002.
-
(2011)
J Infect Dis
, vol.204
, pp. 996-1002
-
-
El Saleeby, C.M.1
Bush, A.J.2
Harrison, L.M.3
Aitken, J.A.4
Devincenzo, J.P.5
-
85
-
-
0037090045
-
Illness severity, viral shedding, and antibody responses in infants hospitalized with bronchiolitis caused by respiratory syncytial virus
-
Wright PF, Gruber WC, Peters M et al. Illness severity, viral shedding, and antibody responses in infants hospitalized with bronchiolitis caused by respiratory syncytial virus. J Infect Dis 2002; 185:1011-1018.
-
(2002)
J Infect Dis
, vol.185
, pp. 1011-1018
-
-
Wright, P.F.1
Gruber, W.C.2
Peters, M.3
-
86
-
-
35548960815
-
Respiratory syncytial virus infections in hospitalized infants: association between viral load, virus subgroup, and disease severity
-
Fodha I, Vabret A, Ghedira L et al. Respiratory syncytial virus infections in hospitalized infants: association between viral load, virus subgroup, and disease severity. J Med Virol 2007; 79:1951-1958.
-
(2007)
J Med Virol
, vol.79
, pp. 1951-1958
-
-
Fodha, I.1
Vabret, A.2
Ghedira, L.3
|