Infected prostheses after lower-extremity bone tumor resection: Clinical outcomes of 100 patients

Surgical Infections

Volumn 16, Issue 3, 2015, Pages 267-275

  Mavrogenis, Andreas F ^a   Pala, Elisa ^a   Angelini, Andrea ^a   Calabro, Teresa ^a   Romagnoli, Carlo ^a   Romantini, Matteo ^a   Drago, Gabriele ^a   Ruggieri, Pietro ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; CEFTRIAXONE; CEFUROXIME; TEICOPLANIN;

ADOLESCENT; ADULT; AGED; ANTIBIOTIC PROPHYLAXIS; ARTICLE; BONE METASTASIS; CEMENTED PROSTHESIS; CEMENTLESS PROSTHESIS; CHILD; CHONDROSARCOMA; EWING SARCOMA; FEMALE; FEMUR PROSTHESIS; GIANT CELL TUMOR; HEMANGIOENDOTHELIOMA; HUMAN; KNEE SURGERY; LEG AMPUTATION; LEG MEGAPROSTHESIS; LEG PROSTHESIS; LIMB SALVAGE; MAJOR CLINICAL STUDY; MALE; MALIGNANT PERIPHERAL NERVE SHEATH TUMOR; MEGAPROSTHESIS INFECTION; OSTEOSARCOMA; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PRIORITY JOURNAL; PROSTHESIS INFECTION; RETROSPECTIVE STUDY; SARCOMA; STAPHYLOCOCCUS EPIDERMIDIS; SURVIVAL RATE; SYNOVIAL SARCOMA; BONE NEOPLASMS; BONES OF THE LEG AND FOOT; INCIDENCE; MIDDLE AGED; PROSTHESIS-RELATED INFECTIONS; SURGICAL WOUND INFECTION; SURVIVAL; TREATMENT OUTCOME; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BONE NEOPLASMS; BONES OF LOWER EXTREMITY; CHILD; FEMALE; HUMANS; INCIDENCE; MALE; MIDDLE AGED; OSTEOSARCOMA; PROSTHESIS-RELATED INFECTIONS; RETROSPECTIVE STUDIES; SURGICAL WOUND INFECTION; SURVIVAL ANALYSIS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84930803836     PISSN: 10962964     EISSN: 15578674     Source Type: Journal    
DOI: 10.1089/sur.2014.085     Document Type: Article

References (37)

1. Jeys LM, Kulkarni A, Grimer RJ, et al. Endoprosthetic reconstruction for the treatment of musculoskeletal tumors of the appendicular skeleton and pelvis. J Bone Joint Surg [Am] 2008;90:1265-1267.
2. Ilyas I, Kurar A, Moreau PG, Younge DA. Modular megaprosthesis for distal femoral tumors. Int Orthop 2001;25: 375-377.
3. Malawer MM, Chou LB. Prosthetic survival and clinical results with use of large-segment replacements in the treatment of high grade bone sarcomas. J Bone Joint Surg [Am] 1995;77:1154-1165.
4. Plotz W, Rechl H, Burgkart R, et al. Limb salvage with tumor endoprostheses for malignant tumors of the knee. Clin Orthop Relat Res 2002;405:207-215.
5. Wirganowicz PC, Eckardt JJ, Dorey FJ, et al. Etiology and results of tumor endoprosthesis revision surgery in 64 patients. Clin Orthop Relat Res 1999;(358):64-74.
6. Shehadeh A, Noveau J, Malawer M, Henshaw R. Late complications and survival of endoprosthetic reconstruction after resection of bone tumors. Clin Orthop Relat Res 2010;(468):2885-2895.
7. Capanna R, Morris HG, Campanacci D, et al. Modular uncemented prosthetic reconstruction after resection of tumours of the distal femur. J Bone Joint Surg [Br] 1994; 76:178-186.
8. Krajbich JI. Modified Van Nes rotationplasty in the treatment of malignant neoplasms in the lower extremities of children. Clin Orthop Relat Res 1991;(262):74-77.
9. Duffy GP, Wood MB, Rock MG, Sim FH. Vascularized free fibular transfer combined with autografting for the management of fracture nonunions associated with radiation therapy. J Bone Joint Surg [Am] 2000;82:544-554.
10. Dick HM, Strauch RJ. Infection of massive bone allografts. Clin Orthop Relat Res 1994;(306):46-53.
11. Gaur AH, Liu T, Knapp KM, et al. Infections in children and young adults with bone malignancies undergoing limbsparing surgery. Cancer 2005;104:602-610.
12. Gitelis S, Yergler J, Sawlani N, et al. Short and long term failure of the modular oncology knee prosthesis. Orthopedics 2008;1:362.
13. Jeys LM, Grimer RJ, Carter SR, et al. Post-operative infection and increased survival in osteosarcoma patients: Are they associated Ann Surg Oncol 2007;14:2887-2895.
14. Jeys LM, Grimer RJ, Carter SR, Tillman RM. Periprosthetic infection in patients treated for an orthopaedic oncological condition. J Bone Joint Surg [Am] 2005;87:842-849.
15. Brigman B, Hornicek FJ, Gebhardt MC, Mankin HJ. Allografts about the knee in young patients with high-grade sarcoma. Clin Orthop Relat Res 2004;(421):232-239.
16. Jeys L, Grimer R, Carter S, Tillman RM. Risk of amputation following limb salvage surgery with endoprosthetic replacement, in a consecutive series of 1261 patients. Int Orthop 2003;27:160-163.
17. Grimer RJ, Belthur M, Chandrasekar C, et al. Two-stage revision for infected endoprostheses used in tumor surgery. Clin Orthop Relat Res 2002;(395):193-203.
18. Coventry MB. Treatment of infections occurring in total hip surgery. Orthop Clin North Am 1975;6:991-1003.
19. Fitzgerald RH Jr, Nolan DR, Ilstrup DM, et al. Deep wound sepsis following total hip arthroplasty. J Bone Joint Surg [Am] 1977;59:847-855.
20. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457-481.
21. Tunney MM, Ramage G, Patrick S, et al. Antimicrobial susceptibility of bacteria isolated from orthopedic implants following revision hip surgery. Antimicrob Agents Chemother 1998;42:3002-3005.
22. Trampuz A, Steckelberg JM, Osmon DR, et al. Advances in the laboratory diagnosis of prosthetic joint infection. Rev Med Microbiol 2003;14:1-14.
23. Steckelberg JM, Osmon DR. Prosthetic joint infections. In: Infections Associated with Indwelling Medical Devices. Bisno AL, Waldvogel FA (eds): Washington, DC: American Society for Microbiology 1994: 259-290.
24. Moran E, Byren I, Atkins BL. The diagnosis and management of prosthetic joint infections. J Antimicrob Chemother 2010;65(Suppl 3):iii45-iii54.
25. Isiklar ZU, Darouiche RO, Landon GC, Beck T. Efficacy of antibiotics alone for orthopaedic device related infections. Clin Orthop Relat Res 1996;(332):184-189.
26. Hanssen AD, Rand JA. Evaluation and treatment of infection at the site of a total hip or knee arthroplasty. J Bone Joint Surg [Am] 1998;80:910-922.
27. Berbari EF, Hanssen AD, Duffy MC, et al. Risk factors for prosthetic joint infection: Case-control study. Clin Infect Dis 1998;27:1247-1254.
28. Hardes J, Gebert C, Schwappach A, et al. Characteristics and outcome of infections associated with tumor endoprostheses. Arch Orthop Trauma Surg 2006;126:289-296.
29. Funovics PT, Hipfl C, Hofstaetter JG, et al. Management of septic complications following modular endoprosthetic reconstruction of the proximal femur. Int Orthop 2011;35: 1437-1444.
30. Jeys LM, Luscombe JS, Grimer RJ, et al. The risks and benefits of radiotherapy with massive endoprosthetic replacement. J Bone Joint Surg [Br] 2007;89:1352-1355.
31. Lee SH, Oh JH, Lee KS, et al. Infection after prosthetic reconstruction in limb salvage surgery. Int Orthop 2002; 26:179-184.
32. Mayilvahanan N, Paraskumar M, Sivaseelam A, Natarajan S. Custom megaprosthetic replacement for proximal humeral tumours. Int Orthop 2006;30:158-162.
33. Sharma S, Turcotte RE, Isler MH, Wong C. Experience with cemented large segment endoprostheses for tumors. Clin Orthop Relat Res 2007;(459):54-59.
34. Grimer RJ, Carter SR, Tillman RM, et al. Endoprosthetic replacement of the proximal tibia. J Bone Joint Surg [Br] 1999;81:488-494.
35. Pala E, Mavrogenis AF, Angelini A, et al. Cemented versus cementless endoprostheses for lower limb salvage surgery. J BUON 2013;18:496-503.
36. Marculescu C, Berbari E, Hanssen A, et al. Outcome of prosthetic joint infections treated with debridement and retention of components. Clin Infect Dis 2006;42:471-478.
37. Flint MN, Griffin AM, Bell RS, et al. Two-stage revision of infected uncemented lower extremity tumor endoprostheses. J Arthroplast 2007;22:859-865.