The risks and benefits of radiotherapy with massive endoprosthetic replacement

Journal of Bone and Joint Surgery - Series B

Volumn 89, Issue 10, 2007, Pages 1352-1355

  Jeys, L M ^a   Luscombe, J S ^a   Grimer, R J ^a   Abudu, A ^a   Tillman, R M ^a   Carter, S R ^a  

^a ROYAL ORTHOPAEDIC HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT;

ARTICLE; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURGERY; CANCER SURVIVAL; CONTROLLED STUDY; ENDOPROSTHESIS; HUMAN; LIMB SALVAGE; MAJOR CLINICAL STUDY; ORTHOPEDIC SURGERY; OSTEOSARCOMA; POSTOPERATIVE CARE; POSTOPERATIVE INFECTION; PREOPERATIVE CARE; PRIORITY JOURNAL; RISK ASSESSMENT; TREATMENT OUTCOME;

AMPUTATION; BONE NEOPLASMS; FEMALE; HUMANS; MALE; NEOPLASMS, CONNECTIVE TISSUE; PROSTHESIS-RELATED INFECTIONS; RADIATION INJURIES; RADIOTHERAPY, ADJUVANT; RISK FACTORS; SARCOMA; TREATMENT OUTCOME;

EID: 36348958421     PISSN: 0301620X     EISSN: None     Source Type: Journal    
DOI: 10.1302/0301-620X.89B10.19233     Document Type: Article

References (21)

1. Jeys LM, Grimer RJ, Carter SR, Tillman RM, Abuda A. A post-operative infection and increased survival in osteosarcoma patients: are they associated? Ann Surg Oncol 2007;14:2887-95.
2. Campanacci M, Bacci G, Pagani P, Guinti A. Multidrug chemotherapy for the treatment of osteosarcoma of extremities. J Bone Joint Surg [Br] 1980;62-B:93-101.
3. Jeys LM, Grimer RJ, Carter SR, Tillman RM. Periprosthetic infection in patients treated for an orthopaedic oncological condition. J Bone Joint Surg [Am] 2005;87-A:842-9.
4. Grimer RJ, Belthur M, Chandrasekar C, Carter SR. Tillman RM. Two-stage revision for infected endoprostheses used in tumor surgery. Clin Orthop 2002;395:193-203.
5. Enneking WF, Durham W, Gebhardt MC, Malawar M, Pritchard DJ. A system for the functional evaluation of the reconstructive procedures after the surgical treatment of tumors of the musculoskeletal system. Clin Orthop 1993;286:241-6.
6. Stone HB. Effects of radiation on normal tissue: consequences and mechanisms. Lancet Oncol 2003;4:529-36.
7. Thompson LH, Suit HD. Proliferation kinetics of X-irradiated mouse L cells studied with time-lapse photography. Int J Radiat Biol 1969;15:347-62.
8. Dent P, Yacoub A, Confessa J, et al. Stress and radiation-induced activation of multiple intracellular signalling pathways. Radiat Res 2003;159:283-300.
9. Chen Y, Williams J, Ding I, et al. Radiation pneumonitis and early circulatory cytokine markers. Semin Radiat Oncol 2002;12(Suppl 1):26-33.
10. Rubin P, Johnston CJ, Williams JP, et al. A perpetual cascade of cytokines postirradiation leads to pulmonary fibrosis. Int J Radiat Oncol Biol Phys 1995;33:99-109.
11. Fu XL, Huang H, Bentel G, et al. Predicting the risk of symptomatic radiation-induced lung injury using both the physical and biologic parameters V(30) and transforming growth factor beta. Int J Radiat Oncol Biol Phys 2001;50:899-908.
12. Paris F, Fuks, Kang A, et al. Endothelial apoptosis as the primary lesion initiating intestinal radiation damage in mice. Science 2001;293:293-7.
13. Hauer-Jensen M, Kong FM, Fink LM, Anscher MS. Circulating thrombomodulin during radiation therapy of lung cancer. Radiat Oncol Investig 1999;7:238-42.
14. Hopewell JW. The importance of vascular damage in the development of late radiation effects in normal tissues. In: Meyn RE, Withers HR, eds. Radiation biology in cancer research. New York: Raven Press, 1980:449-59.
15. Fajardo LF. Morphology of radiation effects on normal tissues. In: Perez CA, Brady LW, eds. Principles and practice of radiation oncology. Second ed. Philadelphia: JB Lippincott Company, 1992:114-23.
16. Hopewell JW, Young CM. Changes in the microcirculation of normal tissues after irradiation. Int J Radiat Oncol Biol Phys 1978;4:53-8.
17. Withers HR, Peters LJ, Kogelnik HD. The pathobiology of late effects of irradiation. In: Meyn RE, Withers HR, eds. Radiation biology in cancer research. New York: Raven Press, 1980:439-48.
18. Krasin MJ, Rodriguez-Galindo C, Davidoff AM, et al. Efficacy of combined surgery and irradiation for localized Ewings sarcoma family of tumors. Pediatr Blood Cancer 2004;43:229-36.
19. Donati D, Yin J, Di Bella C, et al. Local and distant control in non-metastatic pelvic Ewing's sarcoma patients. J Surg Oncol 2007;96:19-25.
20. Yock RI, Krailo M, Fryer CJ, et al. Local control in pelvic Ewing sarcoma: analysis from INT-0091. J Clin Oncol 2006;24:3838-43.
21. O'Sullivan B, Davis AM, Turcotte R, et al. Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial. Lancet 2002;359:2235-41.