Reduced human platelet uptake by pig livers deficient in the asialoglycoprotein receptor 1 protein

Xenotransplantation

Volumn 22, Issue 3, 2015, Pages 203-210

  Paris, Leela L ^a   Estrada, Jose L ^a   Li, Ping ^a   Blankenship, Ross L ^a   Sidner, Richard A ^a   Reyes, Luz M ^a   Montgomery, Jessica B ^a   Burlak, Christopher ^a   Butler, James R ^a   Downey, Susan M ^a   Wang, Zheng Yu ^a   Tector, Matthew ^b   Tector, A Joseph ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY HEALTH   (United States)

Author keywords

ASGR1; asialoglycoprotein; genetically modified; liver xenotransplantation; pigs; platelet; thrombocytopenia; transcription activator like effector nucleases

Indexed keywords

ASIALOGLYCOPROTEIN RECEPTOR; ASIALOGLYCOPROTEIN RECEPTOR 1; TRANSCRIPTION ACTIVATOR LIKE EFFECTOR NUCLEASE; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ARTICLE; ASIALOGLYCOPROTEIN RECEPTOR 1 GENE; BINDING AFFINITY; BINDING ASSAY; CELL TRANSFER; CONTROLLED STUDY; ENZYME ASSAY; EX VIVO STUDY; FETUS; FIBROBLAST; GENE; GENE DELETION; GENE FUNCTION; GENE IDENTIFICATION; HUMAN; HUMAN CELL; LIVER CELL; MOLECULAR DYNAMICS; NONHUMAN; PIG; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; XENOTRANSPLANTATION; ANIMAL; CELL NUCLEUS TRANSPLANTATION; CYTOLOGY; ENDOTHELIUM CELL; GENE INACTIVATION; GENETICS; IMMUNOLOGY; LIVER; METABOLISM; PROCEDURES; THROMBOCYTE; THROMBOCYTOPENIA; XENOGRAFT;

ANIMALS; ASIALOGLYCOPROTEIN RECEPTOR; BLOOD PLATELETS; ENDOTHELIAL CELLS; GENE KNOCKOUT TECHNIQUES; HEPATOCYTES; HUMANS; LIVER; NUCLEAR TRANSFER TECHNIQUES; SWINE; THROMBOCYTOPENIA; TRANSPLANTATION, HETEROLOGOUS;

EID: 84930763375     PISSN: 0908665X     EISSN: 13993089     Source Type: Journal    
DOI: 10.1111/xen.12164     Document Type: Article

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