Panniculitis of the thigh and lung emphysema in a 54-year-old patient;Pannikulitis des Oberschenkels und Lungenemphysem bei einem 54-jährigen Patienten

Internist

Volumn 56, Issue 6, 2015, Pages 696-701

  Eckhard, M ^a,b   Kroll K P ^b   Karrasch, T ^a   Roller, F ^a   Feek, U ^c   Lange, U ^d   Noethe, M ^a   Seeger, W ^a   Ghofrani, S ^a   Schaffler A ^a  

^a UNIVERSITY HOSPITAL GIESSEN   (Germany)

^b Gesundheitszentrum Wetterau Hochwaldkrankenhaus Bad Nauheim   (Germany)

^c Institut für Pathologie und Zytologie   (Germany)

^d KERCKHOFF HEART CENTER   (Germany)

Author keywords

Adipose tissue; Inflammation; Protease inhibitors; Soft tissue edema; 1 antitrypsin deficiency

Indexed keywords

ALPHA 1 ANTITRYPSIN; BIOLOGICAL MARKER;

ADULT; ARTICLE; CASE REPORT; EDEMA; GENE SEQUENCE; HUMAN; LUNG EMPHYSEMA; MALE; MIDDLE AGED; PANNICULITIS; REMISSION; SUBCUTANEOUS FAT; SUBSTITUTION THERAPY; ALPHA 1-ANTITRYPSIN DEFICIENCY; COMPLICATION; DIFFERENTIAL DIAGNOSIS; PULMONARY EMPHYSEMA; THIGH;

ALPHA 1-ANTITRYPSIN DEFICIENCY; DIAGNOSIS, DIFFERENTIAL; HUMANS; MIDDLE AGED; PANNICULITIS; PULMONARY EMPHYSEMA; THIGH;

EID: 84930756965     PISSN: 00209554     EISSN: 14321289     Source Type: Journal    
DOI: 10.1007/s00108-015-3710-3     Document Type: Article

References (10)

1. Schaffler A, Muller-Ladner U, Scholmerich J, Buchler C (2006) Role of adipose tissue as an inflammatory organ in human diseases. Endocr Rev 27:449–467
2. Schäffler A, Schölmerich J, Büchler C (2005) Mechanisms of disease: adipocytokines and visceral adipose tissue – emerging role in intestinal and mesenteric diseases. Nat Clin Pract Gastroenterol Hepatol 2:103–111
3. Hahnel A, Zitzler N, Schardt K et al (2013) 55-jähriger Patient mit abdominellen Schmerzen und Fieber. A 55-year-old man with abdominal pain and fever. Internist (Berl) 54:1256–1261
4. Serres F de, Blanco I (2014) Role of alpha-1 antitrypsin in human health and disease. J Intern Med 276:311–335
5. Fregonese L, Stolk J (2008) Hereditary alpha-1-antitrypsin deficiency and its clinical consequences. Orphanet J Rare Dis 3:16
6. Laureano A, Carvalho R, Chaveiro A, Cardoso J (2014) Alpha-1-antitrypsin deficiency-associated panniculitis: a case report. Dermatol Online J 20:21245
7. Gross B, Grebe M, Wencker M et al (2009) New Findings in PiZZ alpha1-antitrypsin deficiency-related panniculitis. Demonstration of skin polymers and high dosing requirements of intravenous augmentation therapy. Dermatology 218:370–375
8. Ortiz PG, Skov BG, Benfeldt E (2005) Alpha1-antitrypsin deficiency-associated panniculitis: case report and review of treatment options. J Eur Acad Dermatol Venereol 19:487–490
9. Olson JM, Moore EC, Valasek MA et al (2012) Panniculitis in alpha-1 antitrypsin deficiency treated with enzyme replacement. J Am Acad Dermatol 66:e139–e141
10. Al-Niaimi F, Lyon C (2011) Severe ulcerative panniculitis caused by alpha 1-antitrypsin deficiency: remission induced and maintained with intravenous alpha 1-antitrypsin. J Am Acad Dermatol 65:227–229