Severe ulcerative panniculitis caused by alpha 1-antitrypsin deficiency: Remission induced and maintained with intravenous alpha 1-antitrypsin

Journal of the American Academy of Dermatology

Volumn 65, Issue 1, 2011, Pages 227-229

  Al Niaimi, Firas ^a   Lyon, Calum ^b  

^a HOPE HOSPITAL   (United Kingdom)

^b YORK HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTITRYPSIN; DAPSONE; DICLOFENAC; DOXYCYCLINE;

ADOLESCENT; ALPHA 1 ANTITRYPSIN DEFICIENCY; ANAMNESIS; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; DISEASE SEVERITY; DRUG DOSE INCREASE; ERYTHEMA NODOSUM; HUMAN; HUMAN TISSUE; LABORATORY TEST; LEG ULCER; LETTER; LIVER DYSFUNCTION; LUNG FUNCTION TEST; MALE; PANNICULITIS; PRIORITY JOURNAL; REMISSION; SKIN BIOPSY; TREATMENT RESPONSE;

EID: 79958819241     PISSN: 01909622     EISSN: 10976787     Source Type: Journal    
DOI: 10.1016/j.jaad.2009.11.587     Document Type: Article

References (6)

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2. Edmonds BK, Hodge JA, Rietschel RL. Alpha 1-antitrypsin deficiency-associated panniculitis: case report and review of the literature. Pediatr Dermatol 1991;8:296-9.
3. Geller JD, Su WP. A subtle clue to the histopathologic diagnosis of early alpha 1-antitrypsin deficiency panniculitis. J Am Acad Dermatol 1994;31(2 pt 1):241-5. (Pubitemid 24242862)
4. Su WPD, Smith KC, Pittelkow MR, Winkelmann RK. Alpha 1-antitrypsin deficiency panniculitis: a histopathologic and immunopathologic study of four cases. Am J Dermatopathol 1987;9:483-90. (Pubitemid 18014635)
5. Smith KC, Pittelkow MR, Su WPD. Panniculitis associated with severe alpha 1-antitrypsin deficiency. Arch Dermatol 1987;123:1655-61.
6. Chowdhury MM, Williams EJ, Morris JS, Ferguson BJ, McGregor AD, Hedges AR, et al. Severe panniculitis caused by homozygous ZZ alpha1-antitrypsin deficiency treated successfully with human purified enzyme (Prolastin). Br J Dermatol 2002;147:1258-61. (Pubitemid 36963038)