Acute symptoms during the course of head and neck radiotherapy or chemoradiation are strong predictors of late dysphagia

Radiotherapy and Oncology

Volumn 115, Issue 1, 2015, Pages 56-62

  Van Der Laan, Bernard F A M ^a   Van Der Laan, Hans Paul ^a   Bijl, Hendrik P ^a   Steenbakkers, Roel J H M ^a   Van Der Schaaf, Arjen ^a   Chouvalova, Olga ^a   Vemer Van Den Hoek, Johanna G M ^a   Gawryszuk, Agata ^a   Oosting, Sjoukje F ^a   Roodenburg, Jan L N ^a   Wopken, Kim ^a   Langendijk, Johannes A ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

Author keywords

Acute symptoms; Head and neck cancer; IMRT; Prediction models; Swallowing dysfunction

Indexed keywords

CETUXIMAB;

ADULT; ARTICLE; CHEMORADIOTHERAPY; COMPUTER ASSISTED RADIOTHERAPY; DIAGNOSTIC TEST ACCURACY STUDY; DYSPHAGIA; FEMALE; HEAD AND NECK CANCER; HIGH RISK PATIENT; HUMAN; INTENSITY MODULATED RADIATION THERAPY; LOW RISK PATIENT; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; ORAL MUCOSITIS; ORGANS AT RISK; PREDICTIVE VALUE; PREDICTOR VARIABLE; PRIORITY JOURNAL; PROGNOSIS; SENSITIVITY AND SPECIFICITY; SYMPTOM; SYMPTOM ASSESSMENT; XEROSTOMIA; ACUTE DISEASE; ADOLESCENT; AGED; CHEMICALLY INDUCED; COHORT ANALYSIS; COMPLICATION; DEGLUTITION DISORDERS; HEAD AND NECK NEOPLASMS; PROSPECTIVE STUDY; STOMATITIS; SWALLOWING; YOUNG ADULT;

ACUTE DISEASE; ADOLESCENT; ADULT; AGED; CHEMORADIOTHERAPY; COHORT STUDIES; DEGLUTITION; DEGLUTITION DISORDERS; FEMALE; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; STOMATITIS; XEROSTOMIA; YOUNG ADULT;

EID: 84930753729     PISSN: 01678140     EISSN: 18790887     Source Type: Journal    
DOI: 10.1016/j.radonc.2015.01.019     Document Type: Article

References (25)

1. J.A. Langendijk, P. Doornaert, and Leeuw Verdonck-de Impact of late treatment-related toxicity on quality of life among patients with head and neck cancer treated with radiotherapy J Clin Oncol 26 2008 3770 3776
2. M.R. Vergeer, P.A. Doornaert, and D.H. Rietveld Intensity-modulated radiotherapy reduces radiation-induced morbidity and improves health-related quality of life: results of a nonrandomized prospective study using a standardized follow-up program Int J Radiat Oncol Biol Phys 74 2009 1 8
3. F.Y. Feng, H.M. Kim, and T.H. Lyden Intensity-modulated chemoradiotherapy aiming to reduce dysphagia in patients with oropharyngeal cancer: clinical and functional results J Clin Oncol 28 2010 2732 2738
4. B.L. Ramaekers, M.A. Joore, and J.P. Grutters The impact of late treatment-toxicity on generic health-related quality of life in head and neck cancer patients after radiotherapy Oral Oncol 47 2011 768 774
5. P. Dirix, S. Abbeel, and B. Vanstraelen Dysphagia after chemoradiotherapy for head-and-neck squamous cell carcinoma: dose-effect relationships for the swallowing structures Int J Radiat Oncol Biol Phys 75 2009 385 392
6. M.E. Christianen, C. Schilstra, and I. Beetz Predictive modelling for swallowing dysfunction after primary (chemo)radiation: results of a prospective observational study Radiother Oncol 105 2012 107 114
7. H.P. van der Laan, M.E.M.C. Christianen, and H.P. Bijl The potential benefit of swallowing sparing intensity-modulated radiotherapy to reduce swallowing dysfunction: an in silico planning comparative study Radiother Oncol 103 2012 76 81
8. H.P. van der Laan, A. Gawryszuk, and M.E. Christianen Swallowing-sparing intensity-modulated radiotherapy for head and neck cancer patients: treatment planning optimization and clinical introduction Radiother Oncol 107 2013 282 287
9. J.D. Cox, J. Stetz, and T.F. Pajak Toxicity criteria of the radiation therapy oncology group (RTOG) and the european organization for research and treatment of cancer (EORTC) Int J Radiat Oncol Biol Phys 31 1995 1341 1346
10. M.E. Christianen, J.A. Langendijk, and H.E. Westerlaan Delineation of organs at risk involved in swallowing for radiotherapy treatment planning Radiother Oncol 101 2011 394 402
11. T.A. van de Water, H.P. Bijl, and H.E. Westerlaan Delineation guidelines for organs at risk involved in radiation-induced salivary dysfunction and xerostomia Radiother Oncol 93 2009 545 552
12. E.W. Steyerberg, F.E. Harrell Jr, and G.J. Borsboom Internal validation of predictive models: efficiency of some procedures for logistic regression analysis J Clin Epidemiol 54 2001 774 781
13. S. Nuyts, M. Lambrecht, and F. Duprez Reduction of the dose to the elective neck in head and neck squamous cell carcinoma, a randomized clinical trial using intensity modulated radiotherapy (IMRT). Dosimetrical analysis and effect on acute toxicity Radiother Oncol 109 2013 323 329
14. H.P. van der Laan, T.A. van de Water, and H.E. van Herpt The potential of intensity-modulated proton radiotherapy to reduce swallowing dysfunction in the treatment of head and neck cancer: a planning comparative study Acta Oncol 52 2013 561 569
15. N. Ghazali, R.J. Shaw, and S.N. Rogers Genomic determinants of normal tissue toxicity after radiotherapy for head and neck malignancy: a systematic review Oral Oncol 48 2012 1090 1100
16. G.C. Barnett, C.M. West, and A.M. Dunning Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype Nat Rev Cancer 9 2009 134 142
17. W.D. Heemsbergen, S.T. Peeters, and P.C. Koper Acute and late gastrointestinal toxicity after radiotherapy in prostate cancer patients: consequential late damage Int J Radiat Oncol Biol Phys 66 2006 3 10
18. M. Pinkawa, R. Holy, and M.D. Piroth Consequential late effects after radiotherapy for prostate cancer - a prospective longitudinal quality of life study Radiat Oncol 5 2010 27
19. S.M. Bentzen Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology Nat Rev Cancer 6 2006 702 713
20. W. Dorr, and J.H. Hendry Consequential late effects in normal tissues Radiother Oncol 61 2001 223 231
21. J.L. Krull, and D.P. MacKinnon Multilevel mediation modeling in group-based intervention studies Eval Rev 23 1999 418 444
22. D.P. MacKinnon, J.L. Krull, and C.M. Lockwood Equivalence of the mediation, confounding and suppression effect Prev Sci 1 2000 173 181
23. H.R. Mortensen, J. Overgaard, and K. Jensen Factors associated with acute and late dysphagia in the DAHANCA 6 & 7 randomized trial with accelerated radiotherapy for head and neck cancer Acta Oncol 52 2013 1535 1542
24. L.J. Wedlake, K. Thomas, and A. Lalji Predicting late effects of pelvic radiotherapy: is there a better approach? Int J Radiat Oncol Biol Phys 78 2010 1163 1170
25. G.C. Barnett, C.M. West, and C.E. Coles Standardized total average toxicity score: a scale- and grade-independent measure of late radiotherapy toxicity to facilitate pooling of data from different studies Int J Radiat Oncol Biol Phys 82 2012 1065 1074