-
1
-
-
58249113980
-
Mammalian nicotinic acetylcholine receptors: From structure to function
-
Albuquerque EX, Pereira EF, Alkondon M, et al. Mammalian nicotinic acetylcholine receptors: From structure to function. Physiol Rev. 2009 ; 89: 73-120
-
(2009)
Physiol Rev
, vol.89
, pp. 73-120
-
-
Albuquerque, E.X.1
Pereira, E.F.2
Alkondon, M.3
-
2
-
-
0032845951
-
Treatment of acute opioid withdrawal with ibogaine
-
Alper KR, Lotsof HS, Frenken GM, et al. Treatment of acute opioid withdrawal with ibogaine. Am J Addict. 1999 ; 8: 234-242
-
(1999)
Am J Addict
, vol.8
, pp. 234-242
-
-
Alper, K.R.1
Lotsof, H.S.2
Frenken, G.M.3
-
3
-
-
67651089681
-
Modafinil for the treatment of cocaine dependence
-
Anderson AL, Reid MS, Li SH, et al. Modafinil for the treatment of cocaine dependence. Drug Alcohol Depend. 2009 ; 104: 133-139
-
(2009)
Drug Alcohol Depend
, vol.104
, pp. 133-139
-
-
Anderson, A.L.1
Reid, M.S.2
Li, S.H.3
-
4
-
-
0031024617
-
Ibogaine: A potent noncompetitive blocker of ganglionic/neuronal nicotinic receptors
-
Badio B, Padgett WL, Daly JW. Ibogaine: A potent noncompetitive blocker of ganglionic/neuronal nicotinic receptors. Mol Pharmacol. 1997 ; 51: 1-5
-
(1997)
Mol Pharmacol
, vol.51
, pp. 1-5
-
-
Badio, B.1
Padgett, W.L.2
Daly, J.W.3
-
6
-
-
84871386207
-
Preclinical determinants of drug choice under concurrent schedules of drug self-administration
-
2012
-
Banks ML, Negus SS. Preclinical determinants of drug choice under concurrent schedules of drug self-administration. Adv Pharmacol Sc. 2012 2012 ;: 1-17
-
(2012)
Adv Pharmacol Sc
, pp. 1-17
-
-
Banks, M.L.1
Negus, S.S.2
-
7
-
-
0035232406
-
Comparative neuropharmacology of ibogaine and its O-desmethyl metabolite, noribogaine
-
Baumann MH, Pablo J, Ali SF, et al. Comparative neuropharmacology of ibogaine and its O-desmethyl metabolite, noribogaine. Alkaloids Chem Biol. 2001a ; 56: 79-113
-
(2001)
Alkaloids Chem Biol
, vol.56
, pp. 79-113
-
-
Baumann, M.H.1
Pablo, J.2
Ali, S.F.3
-
8
-
-
0035032863
-
In vivo neurobiological effects of ibogaine and its O-desmethyl metabolite, 12-hydroxyibogamine (noribogaine), in rats
-
Baumann MH, Rothman RB, Pablo JP, et al. In vivo neurobiological effects of ibogaine and its O-desmethyl metabolite, 12-hydroxyibogamine (noribogaine), in rats. J Pharmacol Exp Ther. 2001b ; 297: 531-539
-
(2001)
J Pharmacol Exp Ther
, vol.297
, pp. 531-539
-
-
Baumann, M.H.1
Rothman, R.B.2
Pablo, J.P.3
-
9
-
-
65249154248
-
Pharmacology of nicotine: Addiction, smoking-induced disease, and therapeutics
-
Benowitz NL. Pharmacology of nicotine: Addiction, smoking-induced disease, and therapeutics. Annu Rev Pharmacol Toxicol. 2009 ; 49: 57-71
-
(2009)
Annu Rev Pharmacol Toxicol
, vol.49
, pp. 57-71
-
-
Benowitz, N.L.1
-
10
-
-
33745756525
-
Genetic dissociation of two behaviors associated with nicotine addiction: Beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome
-
Besson M, David V, Suarez S, et al. Genetic dissociation of two behaviors associated with nicotine addiction: Beta-2 containing nicotinic receptors are involved in nicotine reinforcement but not in withdrawal syndrome. Psychopharmacology (Berl). 2006 ; 187: 189-199
-
(2006)
Psychopharmacology (Berl)
, vol.187
, pp. 189-199
-
-
Besson, M.1
David, V.2
Suarez, S.3
-
12
-
-
77952692954
-
Nicotine addiction and nicotinic receptors: Lessons from genetically modified mice
-
Changeux JP. Nicotine addiction and nicotinic receptors: Lessons from genetically modified mice. Nat Rev Neurosci. 2010 ; 11: 389-401
-
(2010)
Nat Rev Neurosci
, vol.11
, pp. 389-401
-
-
Changeux, J.P.1
-
13
-
-
78651407161
-
Partial agonists of the alpha3beta4∗ neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats
-
Chatterjee S, Steensland P, Simms JA, et al. Partial agonists of the alpha3beta4∗ neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats. Neuropsychopharmacology. 2011 ; 36: 603-615
-
(2011)
Neuropsychopharmacology
, vol.36
, pp. 603-615
-
-
Chatterjee, S.1
Steensland, P.2
Simms, J.A.3
-
14
-
-
20844441945
-
Varenicline: An alpha4beta2 nicotinic receptor partial agonist for smoking cessation
-
Coe JW, Brooks PR, Vetelino MG, et al. Varenicline: An alpha4beta2 nicotinic receptor partial agonist for smoking cessation. J Med Chem. 2005 ; 48: 3474-3477
-
(2005)
J Med Chem
, vol.48
, pp. 3474-3477
-
-
Coe, J.W.1
Brooks, P.R.2
Vetelino, M.G.3
-
15
-
-
84866416702
-
A double-blind, placebo-controlled trial of modafinil for cocaine dependence
-
Dackis CA, Kampman KM, Lynch KG, et al. A double-blind, placebo-controlled trial of modafinil for cocaine dependence. J Subst Abuse Treat. 2012 ; 43: 303-312
-
(2012)
J Subst Abuse Treat
, vol.43
, pp. 303-312
-
-
Dackis, C.A.1
Kampman, K.M.2
Lynch, K.G.3
-
16
-
-
84930625831
-
Ibogaine: A novel anti-addictive compound
-
Freedlander J. Ibogaine: A novel anti-addictive compound. J Drug Addict Educ Erad. 2003 ; 1: 79-98
-
(2003)
J Drug Addict Educ Erad
, vol.1
, pp. 79-98
-
-
Freedlander, J.1
-
17
-
-
0032934644
-
Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine
-
Fryer JD, Lukas RJ. Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine. J Pharmacol Exp Ther. 1999 ; 288: 88-92
-
(1999)
J Pharmacol Exp Ther
, vol.288
, pp. 88-92
-
-
Fryer, J.D.1
Lukas, R.J.2
-
18
-
-
0029932986
-
18-Methoxycoronaridine, a non-toxic iboga alkaloid congener: Effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats
-
Glick SD, Kuehne ME, Maisonneuve IM, et al. 18-Methoxycoronaridine, a non-toxic iboga alkaloid congener: Effects on morphine and cocaine self-administration and on mesolimbic dopamine release in rats. Brain Res. 1996 ; 719: 29-35
-
(1996)
Brain Res
, vol.719
, pp. 29-35
-
-
Glick, S.D.1
Kuehne, M.E.2
Maisonneuve, I.M.3
-
19
-
-
0033710757
-
18-Methoxycoronaridine (18-MC) and ibogaine: Comparison of antiaddictive efficacy, toxicity, and mechanisms of action
-
Glick SD, Maisonneuve IM, Szumlinski KK. 18-Methoxycoronaridine (18-MC) and ibogaine: Comparison of antiaddictive efficacy, toxicity, and mechanisms of action. Ann N Y Acad Sci. 2000 ; 914: 369-386
-
(2000)
Ann N y Acad Sci
, vol.914
, pp. 369-386
-
-
Glick, S.D.1
Maisonneuve, I.M.2
Szumlinski, K.K.3
-
20
-
-
84921032883
-
Ascending-dose study of Noribogaine in healthy volunteers: Pharmacokinetics, pharmacodynamics, safety, and tolerability
-
Glue P, Lockhart M, Lam F, et al. Ascending-dose study of Noribogaine in healthy volunteers: Pharmacokinetics, pharmacodynamics, safety, and tolerability. J Clin Pharmacol. 2015 ; 55: 189-194
-
(2015)
J Clin Pharmacol
, vol.55
, pp. 189-194
-
-
Glue, P.1
Lockhart, M.2
Lam, F.3
-
21
-
-
0002723938
-
Pharmacodynamics and therapeutic applications of Iboga and Ibogaine (Translated from French by Gladstone WJ)
-
Goutarel R, Golnhoffer N, Siddens R. Pharmacodynamics and therapeutic applications of Iboga and Ibogaine (Translated from French by Gladstone WJ). Psychedelic Monogr Essays. 1993 ; 6: 70-111
-
(1993)
Psychedelic Monogr Essays
, vol.6
, pp. 70-111
-
-
Goutarel, R.1
Golnhoffer, N.2
Siddens, R.3
-
22
-
-
84877699097
-
Neuronal nicotinic acetylcholine receptors: Common molecular substrates of nicotine and alcohol dependence
-
Hendrickson LM, Guildford MJ, Tapper AR. Neuronal nicotinic acetylcholine receptors: Common molecular substrates of nicotine and alcohol dependence. Front Psychiatry. 2013 ; 4: 29
-
(2013)
Front Psychiatry
, vol.4
, pp. 29
-
-
Hendrickson, L.M.1
Guildford, M.J.2
Tapper, A.R.3
-
23
-
-
84858332463
-
The 5-HT2C receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: Relationship to feeding behavior and impulse control
-
Higgins GA, Silenieks LB, Rossmann A, et al. The 5-HT2C receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: Relationship to feeding behavior and impulse control. Neuropsychopharmacology. 2012 ; 37: 1177-1191
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 1177-1191
-
-
Higgins, G.A.1
Silenieks, L.B.2
Rossmann, A.3
-
24
-
-
77955351121
-
The nicotinic acetylcholine receptor CHRNA5/A3/B4 gene cluster: Dual role in nicotine addiction and lung cancer
-
Improgo MR, Scofield MD, Tapper AR, et al. The nicotinic acetylcholine receptor CHRNA5/A3/B4 gene cluster: Dual role in nicotine addiction and lung cancer. Prog Neurobiol. 2010 ; 92: 212-226
-
(2010)
Prog Neurobiol
, vol.92
, pp. 212-226
-
-
Improgo, M.R.1
Scofield, M.D.2
Tapper, A.R.3
-
25
-
-
33947283637
-
Pharmacotherapy of dual substance abuse and dependence
-
Kenna GA, Nielsen DM, Mello P, et al. Pharmacotherapy of dual substance abuse and dependence. CNS Drugs. 2007 ; 21: 213-237
-
(2007)
CNS Drugs
, vol.21
, pp. 213-237
-
-
Kenna, G.A.1
Nielsen, D.M.2
Mello, P.3
-
26
-
-
0035199891
-
Drug addiction, dysregulation of reward, and allostasis
-
Koob GF, Le Moal M. Drug addiction, dysregulation of reward, and allostasis. Neuropsychopharmacology. 2001 ; 24: 97-129
-
(2001)
Neuropsychopharmacology
, vol.24
, pp. 97-129
-
-
Koob, G.F.1
Le Moal, M.2
-
27
-
-
57549091865
-
Nicotinic alpha7- or beta2-containing receptor knockout: Effects on radial-arm maze learning and long-term nicotine consumption in mice
-
Levin ED, Petro A, Rezvani AH, et al. Nicotinic alpha7- or beta2-containing receptor knockout: Effects on radial-arm maze learning and long-term nicotine consumption in mice. Behav Brain Res. 2009 ; 196: 207-213
-
(2009)
Behav Brain Res
, vol.196
, pp. 207-213
-
-
Levin, E.D.1
Petro, A.2
Rezvani, A.H.3
-
28
-
-
0004123929
-
-
1997) Substance Abuse: A Comprehensive Textbook. 3rd ed. Philadelphia, PA: Williams & Wilkens. Philadelphia, PA: Williams & Wilkens;
-
Lowinson JH, Ruiz P, Millman P, et al Substance Abuse: A Comprehensive Textbook. 1997 ) Substance Abuse: A Comprehensive Textbook. 3rd ed. Philadelphia, PA: Williams & Wilkens. Philadelphia, PA: Williams & Wilkens ; 1997 :
-
(1997)
Substance Abuse: A Comprehensive Textbook
-
-
Lowinson, J.H.1
Ruiz, P.2
Millman, P.3
-
29
-
-
51649088921
-
Ibogaine, an anti-addictive drug: Pharmacology and time to go further in development. A narrative review
-
Maciulaitis R, Kontrimaviciute V, Bressolle FM, et al. Ibogaine, an anti-addictive drug: Pharmacology and time to go further in development. A narrative review. Hum Exp Toxicol. 2008 ; 27: 181-194
-
(2008)
Hum Exp Toxicol
, vol.27
, pp. 181-194
-
-
Maciulaitis, R.1
Kontrimaviciute, V.2
Bressolle, F.M.3
-
32
-
-
0029042958
-
Identification of a primary metabolite of ibogaine that targets serotonin transporters and elevates serotonin
-
Mash DC, Staley JK, Baumann MH. Identification of a primary metabolite of ibogaine that targets serotonin transporters and elevates serotonin. Life Sci. 1995a ; 57: PL45-50
-
(1995)
Life Sci
, vol.57
, pp. 45-50
-
-
Mash, D.C.1
Staley, J.K.2
Baumann, M.H.3
-
33
-
-
0029001030
-
Properties of ibogaine and its principal metabolite (12-hydroxyibogamine) at the MK-801 binding site of the NMDA receptor complex
-
Mash DC, Staley JK, Pablo JP, et al. Properties of ibogaine and its principal metabolite (12-hydroxyibogamine) at the MK-801 binding site of the NMDA receptor complex. Neurosci Lett. 1995b ; 192: 53-56
-
(1995)
Neurosci Lett
, vol.192
, pp. 53-56
-
-
Mash, D.C.1
Staley, J.K.2
Pablo, J.P.3
-
34
-
-
0007055379
-
Preclinical screening of an ibogaine metabolite (noribogaine) on cocaine-induced hyperlocomotion and cocaine self-administration
-
1929
-
Mash DC, Schenck S. Preclinical screening of an ibogaine metabolite (noribogaine) on cocaine-induced hyperlocomotion and cocaine self-administration. Soc Neurosci Abstr. 1996 1929 ; 22 :
-
(1996)
Soc Neurosci Abstr
, vol.22
-
-
Mash, D.C.1
Schenck, S.2
-
35
-
-
0031845374
-
Medication development of ibogaine as a pharmacotherapy for drug dependence
-
Mash DC, Kovera CA, Buck BE, et al. Medication development of ibogaine as a pharmacotherapy for drug dependence. Ann N Y Acad Sci. 1998 ; 844: 274-292
-
(1998)
Ann N y Acad Sci
, vol.844
, pp. 274-292
-
-
Mash, D.C.1
Kovera, C.A.2
Buck, B.E.3
-
36
-
-
0033711410
-
Ibogaine: Complex pharmacokinetics, concerns for safety, and preliminary efficacy measures
-
Mash DC, Kovera CA, Pablo J, et al. Ibogaine: Complex pharmacokinetics, concerns for safety, and preliminary efficacy measures. Ann N Y Acad Sci. 2000 ; 914: 394-401
-
(2000)
Ann N y Acad Sci
, vol.914
, pp. 394-401
-
-
Mash, D.C.1
Kovera, C.A.2
Pablo, J.3
-
37
-
-
33747598710
-
Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors
-
Mihalak KB, Carroll FI, Luetje CW. Varenicline is a partial agonist at alpha4beta2 and a full agonist at alpha7 neuronal nicotinic receptors. Mol Pharmacol. 2006 ; 70: 801-805
-
(2006)
Mol Pharmacol
, vol.70
, pp. 801-805
-
-
Mihalak, K.B.1
Carroll, F.I.2
Luetje, C.W.3
-
38
-
-
84871910924
-
-
2011) Committee for the Update of the Guide for the Care and Use of Laboratory Animals. Guide for the Care and Use of Laboratory Animals. 8th ed. Washington, DC: National Academies Press. Washington, DC: National Academies Press;
-
Committee for the Update of the Guide for the Care and Use of Laboratory Animals. Guide for the Care and Use of Laboratory Animals. 2011 ) Committee for the Update of the Guide for the Care and Use of Laboratory Animals. Guide for the Care and Use of Laboratory Animals. 8th ed. Washington, DC: National Academies Press. Washington, DC: National Academies Press ; 2011 :
-
(2011)
Committee for the Update of the Guide for the Care and Use of Laboratory Animals. Guide for the Care and Use of Laboratory Animals
-
-
-
39
-
-
0031846628
-
Cytochrome P4502D6 catalyzes the O-demethylation of the psychoactive alkaloid ibogaine to 12-hydroxyibogamine
-
Obach RS, Pablo J, Mash DC. Cytochrome P4502D6 catalyzes the O-demethylation of the psychoactive alkaloid ibogaine to 12-hydroxyibogamine. Drug Metab Dispos. 1998 ; 26: 764-768
-
(1998)
Drug Metab Dispos
, vol.26
, pp. 764-768
-
-
Obach, R.S.1
Pablo, J.2
Mash, D.C.3
-
40
-
-
80052971027
-
Natural rewards, neuroplasticity, and non-drug addictions
-
Olsen CM. Natural rewards, neuroplasticity, and non-drug addictions. Neuropharmacology. 2011 ; 61: 1109-1122
-
(2011)
Neuropharmacology
, vol.61
, pp. 1109-1122
-
-
Olsen, C.M.1
-
41
-
-
0032495515
-
Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine
-
Picciotto MR, Zoli M, Rimondini R, et al. Acetylcholine receptors containing the beta2 subunit are involved in the reinforcing properties of nicotine. Nature. 1998 ; 391: 173-177
-
(1998)
Nature
, vol.391
, pp. 173-177
-
-
Picciotto, M.R.1
Zoli, M.2
Rimondini, R.3
-
42
-
-
84862673941
-
Effect of fenfluramine on reinstatement of food seeking in female and male rats: Implications for the predictive validity of the reinstatement model
-
Pickens CL, Cifani C, Navarre BM, et al. Effect of fenfluramine on reinstatement of food seeking in female and male rats: Implications for the predictive validity of the reinstatement model. Psychopharmacology (Berl). 2012 ; 221: 341-353
-
(2012)
Psychopharmacology (Berl)
, vol.221
, pp. 341-353
-
-
Pickens, C.L.1
Cifani, C.2
Navarre, B.M.3
-
43
-
-
0010628682
-
Noribogaine, a primary Ibogaine metabolite, reduces alcohol intake in P and fawn-hooded rats
-
Rezvani AH, Mash DC, Hearn WL, et al. Noribogaine, a primary Ibogaine metabolite, reduces alcohol intake in P and fawn-hooded rats. Alcohol Clin Exp Res. 1995a ; 19: 15A
-
(1995)
Alcohol Clin Exp Res
, vol.19
, pp. 15A
-
-
Rezvani, A.H.1
Mash, D.C.2
Hearn, W.L.3
-
44
-
-
0029142626
-
Attenuation of alcohol intake by ibogaine in three strains of alcohol-preferring rats
-
Rezvani AH, Overstreet DH, Lee YW. Attenuation of alcohol intake by ibogaine in three strains of alcohol-preferring rats. Pharmacol Biochem Behav. 1995b ; 52: 615-620
-
(1995)
Pharmacol Biochem Behav
, vol.52
, pp. 615-620
-
-
Rezvani, A.H.1
Overstreet, D.H.2
Lee, Y.W.3
-
45
-
-
0030830104
-
Attenuation of alcohol consumption by a novel nontoxic ibogaine analogue (18-methoxycoronaridine) in alcohol-preferring rats
-
Rezvani AH, Overstreet DH, Yang Y, et al. Attenuation of alcohol consumption by a novel nontoxic ibogaine analogue (18-methoxycoronaridine) in alcohol-preferring rats. Pharmacol Biochem Behav. 1997 ; 58: 615-619
-
(1997)
Pharmacol Biochem Behav
, vol.58
, pp. 615-619
-
-
Rezvani, A.H.1
Overstreet, D.H.2
Yang, Y.3
-
46
-
-
0027305458
-
The neural basis of drug craving: An incentive-sensitization theory of addiction
-
Robinson TE, Berridge KC. The neural basis of drug craving: An incentive-sensitization theory of addiction. Brain Res Brain Res Rev. 1993 ; 18: 247-291
-
(1993)
Brain Res Brain Res Rev
, vol.18
, pp. 247-291
-
-
Robinson, T.E.1
Berridge, K.C.2
-
47
-
-
35548997100
-
Decreased withdrawal symptoms but normal tolerance to nicotine in mice null for the alpha7 nicotinic acetylcholine receptor subunit
-
Salas R, Main A, Gangitano D, et al. Decreased withdrawal symptoms but normal tolerance to nicotine in mice null for the alpha7 nicotinic acetylcholine receptor subunit. Neuropharmacology. 2007 ; 53: 863-869
-
(2007)
Neuropharmacology
, vol.53
, pp. 863-869
-
-
Salas, R.1
Main, A.2
Gangitano, D.3
-
48
-
-
0007892952
-
The Bwiti religion and the psychoactive plant Tabernanthe iboga (Equatorial Africa)
-
Samorini G. The Bwiti religion and the psychoactive plant Tabernanthe iboga (Equatorial Africa). Integration. 1995 ; 5: 105-114
-
(1995)
Integration
, vol.5
, pp. 105-114
-
-
Samorini, G.1
-
49
-
-
0030593916
-
Ibogaine selectively inhibits nicotinic receptor-mediated catecholamine release
-
Schneider AS, Nagel JE, Mah SJ. Ibogaine selectively inhibits nicotinic receptor-mediated catecholamine release. Eur J Pharmacol. 1996 ; 317: R1 - R2
-
(1996)
Eur J Pharmacol
, vol.317
, pp. 1-R2
-
-
Schneider, A.S.1
Nagel, J.E.2
Mah, S.J.3
-
50
-
-
0029844299
-
Pharmacological screen for activities of 12-hydroxyibogamine: A primary metabolite of the indole alkaloid ibogaine
-
Staley JK, Ouyang Q, Pablo J, et al. Pharmacological screen for activities of 12-hydroxyibogamine: A primary metabolite of the indole alkaloid ibogaine. Psychopharmacology (Berl). 1996 ; 127: 10-18
-
(1996)
Psychopharmacology (Berl)
, vol.127
, pp. 10-18
-
-
Staley, J.K.1
Ouyang, Q.2
Pablo, J.3
-
51
-
-
84859742106
-
AT-1001: A high affinity and selective alpha3beta4 nicotinic acetylcholine receptor antagonist blocks nicotine self-administration in rats
-
Toll L, Zaveri NT, Polgar WE, et al. AT-1001: A high affinity and selective alpha3beta4 nicotinic acetylcholine receptor antagonist blocks nicotine self-administration in rats. Neuropsychopharmacology. 2012 ; 37: 1367-1376
-
(2012)
Neuropsychopharmacology
, vol.37
, pp. 1367-1376
-
-
Toll, L.1
Zaveri, N.T.2
Polgar, W.E.3
-
52
-
-
0011100512
-
Action inhibitrice de Tabernanthe iboga sur la cholinestérase du sérum
-
Vincent D, Séro I. Action inhibitrice de Tabernanthe iboga sur la cholinestérase du sérum. CR Soc Biol. 1942 ; 136: 612-614
-
(1942)
CR Soc Biol
, vol.136
, pp. 612-614
-
-
Vincent, D.1
Séro, I.2
|