Partial agonists of the α3Β4* neuronal nicotinic acetylcholine receptor reduce ethanol consumption and seeking in rats

Neuropsychopharmacology

Volumn 36, Issue 3, 2011, Pages 603-615

  Chatterjee, Susmita ^a   Steensland, Pia ^b   Simms, Jeffrey A ^a   Holgate, Joan ^a   Coe, Jotham W ^c   Hurst, Raymond S ^c   Shaffer, Christopher L ^c   Lowe, John ^c   Rollema, Hans ^c   Bartlett, Selena E ^a  

^a UNIVERSITY OF CALIFORNIA SAN FRANCISCO   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c PFIZER INC   (United States)

Author keywords

3 4* nicotinic acetylcholine receptor; addiction; drug abuse; ethanol; rat

Indexed keywords

2,3,4,5 TETRAHYDRO 7 (TRIFLUOROMETHYL) 1,5 METHANO 1H 3 BENZAZEPINE; ALCOHOL; CP 601932; DIHYDRO BETA ERYTHROIDINE; NICOTINIC AGENT; NICOTINIC RECEPTOR; NICOTINIC RECEPTOR ALPHA3BETA4; NICOTINIC RECEPTOR ALPHA4BETA2; RAC EXO [6 (2 (PYRIDIN 3 YL) 5 FLUOROPHENOXY)] 3 AZABICYCLO[3.2.1]OCTANE DIHYDROCHLORIDE SALT; SUCROSE; UNCLASSIFIED DRUG; VARENICLINE;

ALCOHOL CONSUMPTION; ALCOHOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; DRUG BRAIN LEVEL; DRUG RECEPTOR BINDING; DRUG SELF ADMINISTRATION; LONG TERM EXPOSURE; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ACETYLCHOLINE; ALCOHOL DRINKING; ANIMALS; AZABICYCLO COMPOUNDS; BEHAVIOR, ANIMAL; BENZAZEPINES; BRAIN; CELL LINE, TRANSFORMED; CHOICE BEHAVIOR; CONDITIONING, OPERANT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; ETHANOL; HUMANS; MALE; NICOTINIC AGONISTS; PROTEIN BINDING; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, NICOTINIC; SELF ADMINISTRATION; TASTE; TIME FACTORS; TRANSFECTION;

EID: 78651407161     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2010.191     Document Type: Article

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