Epidemiology of pediatric functional abdominal pain disorders: A meta-analysis

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Korterink, Judith J ^a   Diederen, Kay ^a   Benninga, Marc A ^a   Tabbers, Merit M ^a  

^a ACADEMIC MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ABDOMINAL PAIN; ABSENTEEISM; AGE DISTRIBUTION; ANXIETY; ARTICLE; ASIA; ATTENTION DEFICIT DISORDER; CONDUCT DISORDER; DEPRESSION; DISEASE ASSOCIATION; EDUCATIONAL STATUS; EMOTIONAL DISORDER; EUROPE; FUNCTIONAL ABDOMINAL PAIN DISORDER; GENDER; HUMAN; INCIDENCE; INCOME; IRRITABLE COLON; PEER PRESSURE; POSTTRAUMATIC STRESS DISORDER; PREVALENCE; QUALITY OF LIFE; RISK FACTOR; SEX DIFFERENCE; SOCIOECONOMICS; SOUTH AMERICA; SYSTEMATIC REVIEW; CHILD; GEOGRAPHY; META ANALYSIS; PATHOPHYSIOLOGY; QUESTIONNAIRE; REPRODUCIBILITY;

ABDOMINAL PAIN; CHILD; GEOGRAPHY; HUMANS; PREVALENCE; REPRODUCIBILITY OF RESULTS; SURVEYS AND QUESTIONNAIRES;

EID: 84930645334     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0126982     Document Type: Article

References (98)

1. Chitkara DK, Rawat DJ, Talley NJ. The epidemiology of childhood recurrent abdominal pain in Western countries: a systematic review. Am J Gastroenterol. 2005 Aug; 100(8):1868-75. PMID: 16086724
2. Spee LA, Lisman-Van Leeuwen Y, Benninga MA, Bierma-Zeinstra SMA, Berger MY. Prevalence, characteristics, and management of childhood functional abdominal pain in general practice. Scand J Prim Health Care. 2013 Dec; 31(4):197-202. doi: 10.3109/02813432.2013.844405 PMID: 24106821
3. Apley J, Naish N. Recurrent abdominal pains: a field survey of 1,000 school children. Arch Dis Child. 1958 Apr; 33(168):165-70. PMID: 13534750
4. Rasquin-Weber A, Hyman PE, Cucchiara S, Fleisher DR, Hyams JS, Milla PJ, et al. Childhood functional gastrointestinal disorders. Gut. 1999 Sep; 45 Suppl 2(Suppl II):II60-8. PMID: 10457047
5. Rasquin A, Di Lorenzo C, Forbes D, Guiraldes E, Hyams JS, Staiano A, et al. Childhood functional gastrointestinal disorders: child/adolescent. Gastroenterology. 2006 Apr; 130(5):1527-37. PMID: 16678566
6. Youssef NN, Atienza K, Langseder AL, Strauss RS. Chronic abdominal pain and depressive symptoms: analysis of the national longitudinal study of adolescent health. Clin Gastroenterol Hepatol. 2008 Mar; 6(3):329-32. doi: 10.1016/j.cgh.2007.12.019 PMID: 18258491
7. Drossman DA, Li Z, Andruzzi E, Temple RD, Talley NJ, Thompson WG, et al. U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact. Dig Dis Sci. 1993 Sep; 38(9):1569-80. PMID: 8359066
8. Gieteling MJ, Bierma-Zeinstra SM, Passchier J, Berger MY. Prognosis of chronic or recurrent abdominal pain in children. Journal of Pediatric Gastroenterology & Nutrition. 2008; 47(3):316-26.
9. Dhroove G, Chogle A, Saps M. A million-dollar work-up for abdominal pain: is it worth it? Journal of Pediatric Gastroenterology & Nutrition. 2010; 51(5):579-83.
10. Di Lorenzo C, Colletti RB, Lehmann HP, Boyle JT, Gerson WT, Hyams JS, et al. Chronic Abdominal Pain In Children: a Technical Report of the American Academy of Pediatrics and the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition. [Review]. Journal of Pediatric Gastroenterology & Nutrition. 2005; 40(3):249-61.
11. Simrén M, Barbara G, Flint HJ, Spiegel BMR, Spiller RC, Vanner S, et al. Intestinal microbiota in functional bowel disorders: a Rome foundation report. Gut. 2013 Jan; 62(1):159-76. doi: 10.1136/gutjnl-2012-302167 PMID: 22730468
12. Koloski NA, Jones M, Kalantar J, Weltman M, Zaguirre J, Talley NJ. The brain-gut pathway in functional gastrointestinal disorders is bidirectional: a 12-year prospective population-based study. Gut. 2012 Sep; 61(9):1284-90. doi: 10.1136/gutjnl-2011-300474 PMID: 22234979
13. Hotopf M, Carr S, Mayou R, Wadsworth M, Wessely S. Why do children have chronic abdominal pain, and what happens to them when they grow up? Population based cohort study. BMJ. 1998 Apr 18; 316(7139):1196-200. PMID: 9552994
14. Hyams JS, Burke G, Davis PM, Rzepski B, Andrulonis PA. Abdominal pain and irritable bowel syndrome in adolescents: A community-based study. J Pediatr. 1996 Aug; 129(2):220-6. PMID: 8765619
15. Sanderson S, Tatt ID, Higgins JPT. Tools for assessing quality and susceptibility to bias in observational studies in epidemiology: a systematic review and annotated bibliography. Int J Epidemiol. 2007 Jun; 36(3):666-76. PMID: 17470488
16. Kmet LM, Lee RC, Cook LS. Standard quality assesment criteria for evaluating primary research papers from a variety of fields. 2004 p. 1-22.
17. Boyle MH. Guidelines for evaluating prevalence studies. Evid Based Ment Heal. 1998;37-9.
18. Higgins JPT, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002 Jun 15; 21(11):1539-58. PMID: 12111919
19. DerSimonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986 Sep; 7(3):177-88. PMID: 3802833
20. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997 Sep 13; 315(7109):629-34. PMID: 9310563
21. Saps M, Nichols-Vinueza DX, Rosen JM, Velasco-Benítez CA. Prevalence of functional gastrointestinal disorders in colombian school children. J Pediatr. 2014 Mar; 164(3):542-5.e1. doi: 10.1016/j.jpeds.2013.10.088 PMID: 24332822
22. Gulewitsch MD, Enck P, Schwille-Kiuntke J, Weimer K, Schlarb AA. Rome III criteria in parents' hands: pain-related functional gastrointestinal disorders in community children and associations with somatic complaints and mental health. Eur J Gastroenterol Hepatol. 2013 Oct; 25(10):1223-9. doi: 10.1097/MEG.0b013e328364b55d PMID: 24002016
23. Romero-Acosta K, Canals J, Hernández-Martínez C, Penelo E, Zolog TC, Domènech-Llaberia E. Age and gender differences of somatic symptoms in children and adolescents. J Ment Health. 2013 Feb; 22(1):33-41. doi: 10.3109/09638237.2012.734655 PMID: 23343045
24. Sagawa T, Okamura S, Kakizaki S, Zhang Y, Morita K, Mori M. Functional gastrointestinal disorders in adolescents and quality of school life. J Gastroenterol Hepatol. 2013 Feb; 28(2):285-90. doi: 10.1111/j.1440-1746.2012.07257.x PMID: 22988951
25. Luntamo T, Sourander A, Rihko M, Aromaa M, Helenius H, Koskelainen M, et al. Psychosocial determinants of headache, abdominal pain, and sleep problems in a community sample of Finnish adolescents. Eur Child Adolesc Psychiatry. 2012 Jun; 21(6):301-13. doi: 10.1007/s00787-012-0261-1 PMID: 22350133
26. Phavichitr N, Koosiriwichian K, Tantibhaedhyangkul R. Prevalence and risk factors of dyspepsia in Thai schoolchildren. J Med Assoc Thai. 2012 May; 95 Suppl 5:S42-7. PMID: 22934444
27. Song S-W, Park S-J, Kim S-H, Kang S-G. Relationship between irritable bowel syndrome, worry and stress in adolescent girls. J Korean Med Sci. 2012 Nov; 27(11):1398-404. doi: 10.3346/jkms.2012.27.11.1398 PMID: 23166424
28. Zheng S, Fu W, Zhou J, Dong X, Liu Z, Wang Y, et al. Prevalence and related factors of irritable bowel syndrome among middle-school students in areas affected by Wenchuan Earthquake: an epidemiological study. J Clin Gastroenterol. 2012 Apr; 46(4):345-6. doi: 10.1097/MCG.0b013e31824712d0 PMID: 22395064
29. Zhou H-Q, Yao M, Chen G-Y, Ding X-D, Chen Y-P, Li D-G. Functional gastrointestinal disorders among adolescents with poor sleep: a school-based study in Shanghai, China. Sleep Breath. 2012 Dec; 16(4):1211-8. doi: 10.1007/s11325-011-0635-5 PMID: 22203339
30. Devanarayana N, Rajindrajith S, Karunanayake A, Nishanthini S, Perera MS, Benninga MA. Abdominal pain predominant functional gastrointestinal diseases: Association with child abuse, traumatic life events and quality of life. Journal of Gastroenterology and Hepatology. 2012. p.383.
31. Devanarayana NM, Mettananda S, Liyanarachchi C, Nanayakkara N, Mendis N, Perera N, et al. Abdominal pain-predominant functional gastrointestinal diseases in children and adolescents: prevalence, symptomatology, and association with emotional stress. J Pediatr Gastroenterol Nutr. 2011 Dec; 53(6):659-65. doi: 10.1097/MPG.0b013e3182296033 PMID: 21697745
32. Devanarayana NM, Adhikari C, Pannala W, Rajindrajith S. Prevalence of functional gastrointestinal diseases in a cohort of Sri Lankan adolescents: comparison between Rome II and Rome III criteria. J Trop Pediatr. 2011 Feb; 57(1):34-9. doi: 10.1093/tropej/fmq039 PMID: 20525779
33. Endo Y, Shoji T, Fukudo S, Machida T, Machida T, Noda S, et al. The features of adolescent irritable bowel syndrome in Japan. J Gastroenterol Hepatol. 2011 Apr; 26 Suppl 3:106-9. doi: 10.1111/j.1440-1746.2011.06637.x PMID: 21443721
34. Liu J, Hou X. A review of the irritable bowel syndrome investigation on epidemiology, pathogenesis and pathophysiology in China. J Gastroenterol Hepatol. 2011 Apr; 26 Suppl 3:88-93. doi: 10.1111/j.1440-1746.2011.06641.x PMID: 21443718
35. Silva AA, Barbieri MA, Cardoso VC, Batista RF, Simões VM, Vianna EO, et al. Prevalence of non-communicable diseases in Brazilian children: follow-up at school age of two Brazilian birth cohorts of the 1990's. BMC Public Health. 2011 Jan; 11:486. doi: 10.1186/1471-2458-11-486 PMID: 21693042
36. Zhou H, Yao M, Cheng G-Y, Chen Y-P, Li D-G. Prevalence and associated factors of functional gastrointestinal disorders and bowel habits in Chinese adolescents: a school-based study. J Pediatr Gastroenterol Nutr. 2011 Aug; 53(2):168-73. doi: 10.1097/MPG.0b013e3182125388 PMID: 21788758
37. Helgeland H, Sandvik L, Mathiesen KS, Kristensen H. Childhood predictors of recurrent abdominal pain in adolescence: A 13-year population-based prospective study. J Psychosom Res. 2010 Apr; 68(4):359-67. doi: 10.1016/j.jpsychores.2009.10.010 PMID: 20307703
38. Zhou H, Li D, Cheng G, Fan J, Lu H. An epidemiologic study of irritable bowel syndrome in adolescents and children in South China: a school-based study. Child Care Health Dev. 2010 Nov; 36(6):781-6. doi: 10.1111/j.1365-2214.2010.01120.x PMID: 20645991
39. Demirceken FG, Kurt G, Dulkadir R, Alpcan A, Bulbul S. Functional dyspepsia in children: A Turkish prospective survey in kirikkale province. Journal of Pediatric Gastroenterology and Nutrition. 2010. p. E122-3.
40. Rask CU, Olsen EM, Elberling H, Christensen MF, Ornbøl E, Fink P, et al. Functional somatic symptoms and associated impairment in 5-7-year-old children: the Copenhagen Child Cohort 2000. Eur J Epidemiol. 2009 Jan; 24(10):625-34. doi: 10.1007/s10654-009-9366-3 PMID: 19633995
41. Telmesani AMA. Helicobacter pylori: prevalence and relationship with abdominal pain in school children in Makkah City, western Saudi Arabia. Saudi J Gastroenterol. Medknow Publications; 2009 Apr 1; 15(2):100-3. doi: 10.4103/1319-3767.45359 PMID: 19568573
42. Alfven G, Ostberg V, Hjern A. Stressor, perceived stress and recurrent pain in Swedish schoolchildren. J Psychosom Res. 2008 Oct; 65(4):381-7. doi: 10.1016/j.jpsychores.2008.07.004 PMID: 18805248
43. Devanarayana NM, de Silva DGH, de Silva HJ. Recurrent abdominal pain syndrome in a cohort of Sri Lankan children and adolescents. J Trop Pediatr. 2008 Jun; 54(3):178-83. doi: 10.1093/tropej/fmm114 PMID: 18204085
44. Son Y-J, Jun E-Y, Park JH. Prevalence and risk factors of irritable bowel syndrome in Korean adolescent girls: a school-based study. Int J Nurs Stud. 2009 Jan; 46(1):76-84. doi: 10.1016/j.ijnurstu.2008.07.006 PMID: 18722617
45. Stanford EA, Chambers CT, Biesanz JC, Chen E. The frequency, trajectories and predictors of adolescent recurrent pain: A population-based approach. Pain. 2008; 138:11-21. PMID: 18093737
46. Brun Sundblad GM, Saartok T, Engström LMT. Prevalence and co-occurrence of self-rated pain and perceived health in school-children: Age and gender differences. Eur J Pain. 2007; 11:171-80. PMID: 16542860
47. Ostberg V, Alfven G, Hjern A. Living conditions and psychosomatic complaints in Swedish schoolchildren. Acta Paediatr. 2006 Aug; 95(8):929-34. PMID: 16882564
48. Dong L, Dingguo L, Xiaoxing X, Hanming L. An epidemiologic study of irritable bowel syndrome in adolescents and children in China: a school-based study. Pediatrics. 2005 Sep; 116(3):e393-6. PMID: 16140684
49. Tindberg Y, Nyren O, Blennow M, Granstrom M. Helicobacter pylori infection and abdominal symptoms among Swedish school children. Journal of Pediatric Gastroenterology & Nutrition. 2005; 41(1):33-8.
50. Oh MC, Aw MM, Chan YH, Tan LZ, Quak SH. Epidemiology of recurrent abdominal pain among Singaporean adolescents. Ann Acad Med Singapore. 2004 Sep; 33(5 Suppl):S10-1. PMID: 15651184
51. Bode G, Brenner H, Adler G, Rothenbacher D. Recurrent abdominal pain in children: evidence from a population-based study that social and familial factors play a major role but not Helicobacter pylori infection. Journal of Psychosomatic Research. 2003; 54(5):417-21. PMID: 12726896
52. Boey CCM, Omar A, Arul Phillips J. Correlation among academic performance, recurrent abdominal pain and other factors in Year-6 urban primary-school children in Malaysia. J Paediatr Child Health. 2003; 39:352-7. PMID: 12887665
53. Petersen S, Bergström E, Brulin C. High prevalence of tiredness and pain in young schoolchildren. Scand J Public Health. 2003 Jan; 31(5):367-74. PMID: 14555373
54. Härmä A-M, Kaltiala-Heino R, Rimpelä M, Rantanen P. Are adolescents with frequent pain symptoms more depressed? Scand J Prim Health Care. 2002 Jun; 20(2):92-6. PMID: 12184720
55. De Giacomo C, Valdambrini V, Lizzoli F, Gissi A, Palestra M, Tinelli C, et al. A population-based survey on gastrointestinal tract symptoms and Helicobacter pylori infection in children and adolescents. Helicobacter. 2002 Dec; 7(6):356-63. PMID: 12485122
56. Boey CCM, Goh KL. Recurrent abdominal pain and consulting behaviour among children in a rural community in Malaysia. Dig Liver Dis. 2001; 33:140-4. PMID: 11346142
57. Boey CCM, Goh KL. Predictors of health-care consultation for recurrent abdominal pain among urban schoolchildren in malaysia. J Gastroenterol Hepatol. 2001; 16:154-9. PMID: 11207895
58. Reshetnikov OV, Kurilovich SA, Denisova DV, Zavyalova LG, Tereshonok IN. Prevalence of dyspepsia and irritable bowel syndrome among adolescents of Novosibirsk, western Siberia. International Journal of Circumpolar Health. 2001; 60(2):253-7. PMID: 11507978
59. Perquin CW, Hazebroek-Kampschreur AA, Hunfeld JA, Bohnen AM, van Suijlekom-Smit LW, Passchier J, et al. Pain in children and adolescents: a common experience. Pain. 2000 Jul; 87(1):51-8. PMID: 10863045
60. Boey CC, Yap SB. An epidemiological survey of recurrent abdominal pain in a rural Malay school. J Paediatr Child Health. 1999 Jun; 35(3):303-5. PMID: 10404456
61. O'Donohoe JM, Sullivan PB, Scott R, Rogers T, Brueton MJ, Barltrop D. Recurrent abdominal pain and Helicobacter pylori in a community-based sample of London children. Acta Paediatr. 1996; 85:961-4. PMID: 8863879
62. Abu-Arafeh I, Russell G. Prevalence and clinical features of abdominal migraine compared with those of migraine headache. Arch Dis Child. 1995 May; 72(5):413-7. PMID: 7618907
63. Christensen MF, Holm E, Sahlholdt I. [Recurrent abdominal pain in Danish school children. A crosssectional study]. Ugeskr Laeger. 1984 Sep 3; 146(36):2690-5. PMID: 6334919
64. Sharrer VW, Ryan-Wenger NM. Measurements of stress and coping among school-aged children with and without recurrent abdominal pain. J Sch Health. 1991 Feb; 61(2):86-91. PMID: 2016865
65. Park H, Lim S. Frequency of irritable bowel syndrome, entrance examination-related stress, mental health, and quality of life in high school students. Gastroenterol Nurs. 2011; 34(6):450-8. doi: 10.1097/ SGA.0b013e318237eb43 PMID: 22129798
66. Sohrabi S, Nouraie M, Khademi H, Baghizadeh S, Nasseri-Moghaddam S, Malekzadeh R. Epidemiology of uninvestigated gastrointestinal symptoms in adolescents: a population-based study applying the Rome II questionnaire. J Pediatr Gastroenterol Nutr. 2010 Jul; 51(1):41-5. doi: 10.1097/MPG.0b013e3181d1b23e PMID: 20543723
67. Malaty HM, Abudayyeh S, Fraley K, Graham DY, Gilger MA, Hollier DR. Recurrent abdominal pain in school children: effect of obesity and diet. Acta Paediatr. 2007 Apr; 96(4):572-6. PMID: 17391473
68. Uc A, Hyman PE, Walker LS. Functional gastrointestinal disorders in African American children in primary care. J Pediatr Gastroenterol Nutr. 2006 Mar; 42(3):270-4. PMID: 16540795
69. Kokkonen J, Haapalahti M, Tikkanen S, Karttunen R, Savilahti E. Gastrointestinal complaints and diagnosis in children: a population-based study. Acta Paediatr. 2004 Jul; 93(7):880-6. PMID: 15303801
70. Mortimer MJ, Kay J, Jaron A. Clinical epidemiology of childhood abdominal migraine in an urban general practice. Dev Med Child Neurol. 1993 Mar; 35(3):243-8. PMID: 8462757
71. Faull C, Nicol AR. Abdominal pain in six-year-olds: an epidemiological study in a new town. J Child Psychol Psychiatry. 1986 Mar; 27(2):251-60. PMID: 3958079
72. Lundby L, Sandbaek A, Juul S. [Recurrent abdominal pain in schoolchildren 9-12 years of age]. Ugeskr Laeger. 1990 Sep 24; 152(39):2851-4. PMID: 2219517
73. Dahl-Larsen R, Buhl SB, Husby S, Qvist N. [Recurrent abdominal pain, dyspepsia and constipation in children aged 9-13. A questionnaire investigation]. Ugeskr Laeger. 2005 Apr 25; 167(17):1848-51. PMID: 15929331
74. Bakoula C, Kapi A, Veltsista A, Kavadias G, Kolaitis G. Prevalence of recurrent complaints of pain among Greek schoolchildren and associated factors: a population-based study. Acta Paediatr. 2006 Aug; 95(8):947-51. PMID: 16882567
75. Grøholt E-K, Stigum H, Nordhagen R, Köhler L. Recurrent pain in children, socio-economic factors and accumulation in families. Eur J Epidemiol. 2003 Jan; 18(10):965-75. PMID: 14598927
76. Li D, Zhou H, Song Y, Zong C, Hu Y, Xu X, et al. [An epidemiologic study of irritable bowel syndrome among adolescents in China]. Zhonghua nei ke za zhi. 2007 Feb; 46(2):99-102. PMID: 17445430
77. Wang Y, Zhang D. The prevalence investigation of IBS in Qinhuandao area. Shandong Med. 2008; 48:107-9.
78. Zhou H-Q, Li D-G, Song Y-Y, Zong C-H, Hu Y, Lu H-M. Epidemiologic study of irritable bowel syndrome among adolescents in Western China. Journal of Shanghai Jiaotong University (Medical Science). China; 2009; 29:581-3.
79. Park JW, Cho Y-S, Lee SY, Kim E-S, Cho H, Shin HE, et al. Concomitant functional gastrointestinal symptoms influence psychological status in Korean migraine patients. Gut and Liver. South Korea; 2013; 7:668-74. doi: 10.5009/gnl.2013.7.6.668 PMID: 24312707
80. Devanarayana NM, de Silva DG, de Silva HJ. Aetiology of recurrent abdominal pain in a cohort of Sri Lankan children. Journal of Paediatrics & Child Health. 2008; 44(4):195-200.
81. Kröner-Herwig B, Morris L, Heinrich M, Gassmann J, Vath N. Agreement of parents and children on characteristics of pediatric headache, other pains, somatic symptoms, and depressive symptoms in an epidemiologic study. Clin J Pain. 2009; 25:58-64. doi: 10.1097/AJP.0b013e31817fc62d PMID: 19158547
82. Sundblad GMB, Saartok T, Engström L-MT. Child-parent agreement on reports of disease, injury and pain. BMC Public Health. 2006; 6:276. PMID: 17092332
83. Sinniah B, Hassan A KR, Sabaridah I, Soe MM, Ibrahim Z, Ali O. Prevalence of intestinal parasitic infections among communities living in different habitats and its comparison with one hundred and one studies conducted over the past 42 years (1970 to 2013) in Malaysia. Trop Biomed. 2014 Jun; 31(2):190-206. PMID: 25134888
84. De Jong MJ, Korterink JJ, Benninga MA, Hilbink M, Widdershoven J, Deckers-Kocken JM. Dientamoeba fragilis and chronic abdominal pain in children: a case-control study. Arch Dis Child. 2014;1-5. doi: 10.1136/archdischild-2014-307251 PMID: 25341553
85. Krogsgaard LR, Engsbro AL, Stensvold CR, Nielsen HV, Bytzer P. The Prevalence of Intestinal Parasites Is Not Greater Among Individuals With Irritable Bowel Syndrome: a Population-Based Case-Control Study. Clin Gastroenterol Hepatol. 2014 Sep 16;
86. Whitehead WE, Cheskin LJ, Heller BR, Robinson JC, Crowell MD, Benjamin C, et al. Evidence for exacerbation of irritable bowel syndrome during menses. Gastroenterology. 1990 Jun; 98(6):1485-9. PMID: 2338190
87. Meleine M, Matricon J. Gender-related differences in irritable bowel syndrome: Potential mechanisms of sex hormones. World J Gastroenterol. 2014 Jun 14; 20(22):6725-43. doi: 10.3748/wjg.v20.i22.6725 PMID: 24944465
88. Wise EA, Price DD, Myers CD, Heft MW, Robinson ME. Gender role expectations of pain: relationship to experimental pain perception. Pain. 2002 Apr; 96(3):335-42. PMID: 11973007
89. Walker LS, Sherman AL, Bruehl S, Garber J, Smith CA. Functional abdominal pain patient subtypes in childhood predict functional gastrointestinal disorders with chronic pain and psychiatric comorbidities in adolescence and adulthood. Pain. 2012 Sep; 153(9):1798-806. doi: 10.1016/j.pain.2012.03.026 PMID: 22721910
90. Mugie SM, Benninga MA, Di Lorenzo C. Epidemiology of constipation in children and adults: a systematic review. Best Pract Res Clin Gastroenterol. Elsevier Ltd; 2011 Feb; 25(1):3-18. doi: 10.1016/j.bpg.2010.12.010 PMID: 21382575
91. Roth-Isigkeit A, Thyen U, Raspe HH, Stöven H, Schmucker P. Reports of pain among German children and adolescents: an epidemiological study. Acta Paediatr. 2004 Feb; 93(2):258-63. PMID: 15046285
92. Cuvellier J-C. [Management of chronic daily headache in children and adolescents]. Rev Neurol (Paris). 2009; 165(6-7):521-31.
93. Walker LS, Smith CA, Garber J, Claar RL. Appraisal and coping with daily stressors by pediatric patients with chronic abdominal pain. J Pediatr Psychol. 2007 Mar; 32(2):206-16. PMID: 16717138
94. Mayer EA, Bradesi S, Chang L, Spiegel BMR, Bueller JA, Naliboff BD. Functional GI disorders: from animal models to drug development. Gut. 2008 Mar; 57(3):384-404. PMID: 17965064
95. Iovino P, Tremolaterra F, Boccia G, Miele E, Ruju FM, Staiano A. Irritable bowel syndrome in childhood: visceral hypersensitivity and psychosocial aspects. Neurogastroenterol Motil. 2009 Sep; 21(9):940-e74. doi: 10.1111/j.1365-2982.2009.01303.x PMID: 19368655
96. Di Lorenzo C, Youssef NN, Sigurdsson L, Scharff L, Griffiths J, Wald A. Visceral hyperalgesia in children with functional abdominal pain. Journal of Pediatrics. United States; 2001. p. 838-43.
97. Mayer EA, Tillisch K. The brain-gut axis in abdominal pain syndromes. Annu Rev Med. 2011 Jan; 62:381-96. doi: 10.1146/annurev-med-012309-103958 PMID: 21090962
98. Zhu J-Z, Yan T-L, Yu C-H, Wan X-Y, Wang Y-M, Li Y-M. Is national socioeconomic status related to prevalence of irritable bowel syndrome? J Gastroenterol Hepatol. 2014 May 29; 29(8):1595-602. doi: 10.1111/jgh.12609 PMID: 24888296