In vivo 7T MRI of the non-human primate brainstem

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Zitella, Laura M ^a   Xiao, YiZi ^a   Teplitzky, Benjamin A ^a   Kastl, Daniel J ^a   Duchin, Yuval ^b   Baker, Kenneth B ^c   Vitek, Jerrold L ^c   Adriany, Gregor ^b   Yacoub, Essa ^b   Harel, Noam ^b   Johnson, Matthew D ^a,b  

^a University of Minnesota   (United States)

^b UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN STEM; DIFFUSION WEIGHTED IMAGING; FEMALE; IMAGE RECONSTRUCTION; IN VIVO STUDY; INFERIOR COLLICULUS; LATERAL LEMNISCUS; MALE; MEDIAL LEMNISCUS; NERVE TRACT; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PEDUNCULOPONTINE TEGMENTAL NUCLEUS; PERIAQUEDUCTAL GRAY MATTER; RHESUS MONKEY; SUPERIOR CEREBELLAR PEDUNCLE; SUSCEPTIBILITY WEIGHTED IMAGING; THREE DIMENSIONAL IMAGING; TRACTOGRAPHY; WHITE MATTER; ALGORITHM; ANATOMIC MODEL; ANATOMY AND HISTOLOGY; ANIMAL; BRAIN; COMPUTER ASSISTED DIAGNOSIS; PROCEDURES;

MACACA MULATTA; PRIMATES;

ALGORITHMS; ANIMALS; BRAIN; DIFFUSION MAGNETIC RESONANCE IMAGING; FEMALE; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMAGING, THREE-DIMENSIONAL; MACACA MULATTA; MALE; MODELS, ANATOMIC;

EID: 84930629489     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0127049     Document Type: Article

References (87)

1. Foltynie T, Zrinzo L, Martinez-Torres I, Tripoliti E, Petersen E, Holl E, et al. MRI-guided STN DBS in Parkinson's disease without microelectrode recording: efficacy and safety. Journal of Neurology, Neurosurgery & Psychiatry. 2011; 82(4):358-63.
2. Giller CA, Dewey RB, Ginsburg MI, Mendelsohn DB, Berk AM. Stereotactic pallidotomy and thalamotomy using individual variations of anatomic landmarks for localization. Neurosurgery. 1998; 42(1):56-62; discussion -5. PMID: 9442504
3. Ashkan K, Blomstedt P, Zrinzo L, Tisch S, Yousry T, Limousin-Dowsey P, et al. Variability of the subthalamic nucleus: The case for direct MRI guided targeting. British Journal of Neurosurgery. 2007; 21 (2):197-200. PMID: 17453788
4. Zrinzo L, Zrinzo LV, Tisch S, Limousin PD, Yousry TA, Afshar F, et al. Stereotactic localization of the human pedunculopontine nucleus: atlas-based coordinates and validation of a magnetic resonance imaging protocol for direct localization. Brain. 2008; 131(Pt 6):1588-98. doi: 10.1093/brain/awn075 PMID: 18467343
5. Mazzone P, Lozano A, Stanzione P, Galati S, Scarnati E, Peppe A, et al. Implantation of human pedunculopontine nucleus: a safe and clinically relevant target in Parkinson's disease. Neuroreport. 2005; 16 (17):1877-81. PMID: 16272871
6. Wilcox RA, Cole MH, Wong D, Coyne T, Silburn P, Kerr G. Pedunculopontine nucleus deep brain stimulation produces sustained improvement in primary progressive freezing of gait. J Neurol Neurosurg Psychiatry. 2010; 82(11):1256-9. doi: 10.1136/jnnp.2010.213462 PMID: 20971757
7. Hamani C, Schwalb JM, Rezai AR, Dostrovsky JO, Davis KD, Lozano AM. Deep brain stimulation for chronic neuropathic pain: Long-term outcome and the incidence of insertional effect. Pain. 2006; 125 (1-2):188-96. PMID: 17069972
8. Lenarz T, Lim HH, Reuter G, Patrick JF, Lenarz M. The Auditory Midbrain Implant: A New Auditory Prosthesis for Neural Deafness-Concept and Device Description. Otology & Neurotology. 2006; 27 (6):838-43.
9. Zitella LM, Mohsenian K, Pahwa M, Gloeckner C, Johnson MD. Computational modeling of pedunculopontine nucleus deep brain stimulation. Journal of neural engineering. 2013; 10(4):045005. doi: 10.1088/1741-2560/10/4/045005 PMID: 23723145
10. Moro E, Hamani C, Poon Y-Y, Al-Khairallah T, Dostrovsky JO, Hutchison WD, et al. Unilateral pedunculopontine stimulation improves falls in Parkinson's disease. Brain. 2010; 133(1):215-24.
11. Plaha P, Gill SS. Bilateral deep brain stimulation of the pedunculopontine nucleus for Parkinson's disease. Neuroreport. 2005; 16(17):1883-7. PMID: 16272872
12. Stefani A, Lozano AM, Peppe A, Stanzione P, Galati S, Tropepi D, et al. Bilateral deep brain stimulation of the pedunculopontine and subthalamic nuclei in severe Parkinson's disease. Brain. 2007; 130(Pt 6):1596-607. PMID: 17251240
13. Alvarez-Linera J. Magnetic Resonance Techniques for the Brainstem. Seminars in Ultrasound, CT and MRI. 2010; 31(3):230-45. doi: 10.1053/j.sult.2010.03.003 PMID: 20483391
14. Nagae-Poetscher LM, Jiang H, Wakana S, Golay X, van Zijl PCM, Mori S. High-Resolution Diffusion Tensor Imaging of the Brain Stem at 3 T. American Journal of Neuroradiology. 2004; 25(8):1325-30. PMID: 15466326
15. Gizewski ER, Maderwald S, Linn J, Dassinger B, Bochmann K, Forsting M, et al. High-resolution anatomy of the human brain stem using 7-T MRI: improved detection of inner structures and nerves? Neuroradiology. 2014; 56(3):177-86. doi: 10.1007/s00234-013-1312-0 PMID: 24357075
16. Weiss M, Alkemade A, Keuken MC, Muller-Axt C, Geyer S, Turner R, et al. Spatial normalization of ultrahigh resolution 7 T magnetic resonance imaging data of the postmortem human subthalamic nucleus: a multistage approach. Brain Struct Funct. 2014.
17. Novak P, Novak V, Kangarlu A, Abduljalil AM, Chakeres DW, Robitaille P. High Resolution MRI of the Brainstem at 8T. Journal of Computer Assisted Tomography. 2001; 25(2):242-6. PMID: 11242222
18. Diedrichsen J, Maderwald S, M. K. Imaging the deep cerebellar nuclei: a probabilistic atlas and normalization procedure. Neuroimaging. 2011; 54:1786-94.
19. Nolte I, Gerigk L, Al-Zghloul M. Visualization of the internal globus pallidus: sequence and orientation for deep brain stimulation using a standard installation procol at 3.0 Tesla. Acta Nuerochir (Wien). 2012; 154(481-494). doi: 10.1007/s00701-011-1242-8 PMID: 22167532
20. Eapen M, Zald DH, Gatenby JC, Ding Z, Gore JC. Using High-Resolution MR Imaging at 7T to Evaluate the Anatomy of the Midbrain Dopaminergic System. American Journal of Neuroradiology. 2011; 32 (4):688-94. doi: 10.3174/ajnr.A2355 PMID: 21183619
21. Sakaie K, Takahashi M, Sagiyama K, Dimitrov I, Frohman T, Remington G, et al. Injury to a specific neural pathway detected by ultra-high-field MRI. Neurology. 2014; 82(2):182-3. doi: 10.1212/WNL.0000000000000016 PMID: 24285615
22. Tani N, Joly O, Iwamuro H, Uhrig L, Wiggins CJ, Poupon C, et al. Direct visualization of non-human primate subcortical nuclei with contrast-enhanced high field MRI. NeuroImage. 2011; 58(1):60-8. doi: 10.1016/j.neuroimage.2011.06.019 PMID: 21704174
23. Marques JP, Gruetter R. New Developments and Applications of the MP2RAGE Sequence-Focusing the Contrast and High Spatial Resolution R Mapping. PLoS One. 2013; 8(7):e69294. doi: 10.1371/journal.pone.0069294 PMID: 23874936
24. Keuken MC, Bazin PL, Crown L, Hootsmans J, Laufer A, Müller-Axt C, et al. Quantifying inter-individual anatomical variability in the subcortex using 7T structural MRI. NeuroImage. 2014; 94(0):40-6.
25. Keuken MC, Bazin PL, Schafer A, Neumann J, Turner R, Forstmann BU. Ultra-High 7T MRI of Structural Age-Related Changes of the Subthalamic Nucleus. J Neurosci. 2013; 33(11):4896-900. doi: 10.1523/JNEUROSCI.3241-12.2013 PMID: 23486960
26. Deistung A, Schafer A, Schweser F, Biederman I, Gullmar D, Trampel R, et al. High-resolution MR imaging of the human brainstem in vivo at 7 Tesla. Frontiers in Human Neuroscience. 2013; 7(710):1-12.
27. Habas C, Cabanis E. Anatomical parcellation of the brainstem and cerebellar white matter: a preliminary probabilistic tractography study at 3 T. Neuroradiology. 2007; 49(10):849-63. PMID: 17701168
28. Janssens T, Keil B, Serano P, Mareyam A, McNab JA, Wald LL, et al. A 22-channel receive array with Helmholtz transmit coil for anesthetized macaque MRI at 3 T. NMR in Biomedicine. 2013; 26(11):1431-40. doi: 10.1002/nbm.2970 PMID: 23703859
29. Ziegler E, Rouillard M, Andre E, Coolen TS, J., Balteau E, Phillips C, et al. Mapping track density changes in nigrostriatal and extranigral pathways in Parkinson's disease. NeuroImage. 2014; 99:498-508. doi: 10.1016/j.neuroimage.2014.06.033 PMID: 24956065
30. Soria G, De Notaris M, Tudela R, Blasco G, Puig J, Planas AM, et al. Improved Assessment of Ex Vivo Brainstem Neuroanatomy With High-Resolution MRI and DTI at 7 Tesla. The Anatomical Record: Advances in Integrative Anatomy and Evolutionary Biology. 2011; 294(6):1035-44.
31. Deistung A, Schafer A, Schweser F, Biedermann U, Gullmar D, Trampel R, et al. High-resolution MR imaging of the human brainstem in vivo at 7 Tesla. Frontiers in Human Neuroscience. 2013; 7 (710):1:12.
32. Lenglet C, Abosch A, Yacoub E, De Martino F, Sapiro G, Harel N. Comprehensive in vivo Mapping of the Human Basal Ganglia and Thalamic Connectome in Individuals Using 7T MRI. PLoS One. 2012; 7 (1):e29153. doi: 10.1371/journal.pone.0029153 PMID: 22235267
33. Stieltjes B, Kaufmann WE, van Zijl PCM, Fredericksen K, Pearlson GD, Solaiyappan M, et al. Diffusion Tensor Imaging and Axonal Tracking in the Human Brainstem. NeuroImage. 2001; 14(3):723-35. PMID: 11506544
34. Yang DS, Hong JH, Byun WM, Kwak SY, Ahn SH, Lee H, et al. Identification of the medial lemniscus in the human brain: Combined study of functional MRI and diffusion tensor tractography. Neurosci Lett. 2009; 459(1):19-24. doi: 10.1016/j.neulet.2009.04.058 PMID: 19409962
35. Muthusamy KA, Aravamuthan BR, Kringelbach ML, Jenkinson N, Voets NL, Johansen-Berg H, et al. Connectivity of the human pedunculopontine nucleus region and diffusion tensor imaging in surgical targeting. Journal of neurosurgery. 2007; 107(4):814-20. PMID: 17937229
36. Sweet JA, Walter BL, Gunalan K, Chaturvedi A, McIntyre CC, Miller JP. Fiber tractography of the axonal pathways linking the basal ganglia and cerebellum in Parkinson disease: implications for targeting in deep brain stimulation. Journal of neurosurgery. 2014; 120(4):988-96. doi: 10.3171/2013.12.JNS131537 PMID: 24484226
37. Aggarwal M, Zhang J, Pletnikova O, Crain B, Troncoso J, Mori S. Feasibility of creating a high-resolution 3D diffusion tensor imaging based atlas of the human brainstem: A case study at 11.7T. Neuro-Image. 2013; 74(0):117-27.
38. Seehaus AK, Roebroeck A, Chiry O, Kim D-S, Ronen I, Bratzke H, et al. Histological Validation of DW-MRI Tractography in Human Postmortem Tissue. Cerebral Cortex. 2013; 23(2):442-50. doi: 10.1093/cercor/bhs036 PMID: 22345356
39. Duchin Y, Abosch A, Yacoub E, Sapiro G, Harel N. Feasibility of Using Ultra-High Field (7 T) MRI for Clinical Surgical Targeting. PLoS One. 2012; 7(5):e37328. doi: 10.1371/journal.pone.0037328 PMID: 22615980
40. Abosch A, Yacoub E, Ugurbil K, Harel N. An Assessment of current brain targets for deep brain stimulation surgery with susceptibility-weighted imaging at 7 tesla. Neurosurg. 2010; 67(6):1745-56. doi: 10.1227/NEU.0b013e3181f74105 PMID: 21107206
41. Duarte-Carvajalino JM, Sapiro G, Harel N, Lenglet C. A Framework for Linear and Non-linear Registration of Diffusion-Weighted MRIs using Angular Interpolation. Front Neurosci. 2013; 7(41). doi: 10.3389/fnins.2013.00041 PMID: 23596381
42. Zhan L, Mueller BA, Jahanshad N, Jin Y, Lenglet C, Yacoub E, et al. Magnetic Resonance Field Strength Effects on Diffusion Measures and Brain Connectivity Networks. Brain Connectivity. 2013; 3 (1):72-86. doi: 10.1089/brain.2012.0114 PMID: 23205551
43. Polders DL, Leemans A, Hendrikse J, Donahue MJ, Luijten PR, Hoogduin JM. Signal to noise ratio and uncertainty in diffusion tensor imaging at 1.5, 3.0, and 7.0 Tesla. JMRI. 2011; 33(6):1456-63. doi: 10.1002/jmri.22554 PMID: 21591016
44. Aravamuthan BR, McNab JA, Miller KL, Rushworth M, Jenkinson N, Stein JF, et al. Cortical and subcortical connections within the pedunculopontine nucleus of the primate Macaca mulatta determined using probabilistic diffusion tractography. Journal of Clinical Neuroscience. 2009; 16(3):413-20. doi: 10.1016/j.jocn.2008.03.018 PMID: 19167229
45. th Annual Meeting of ISMRM. Stockholm, Sweden2010.
46. Stejskal EO, Tanner JE. Spin Diffusion Measurements: Spin Echoes in the Presence of a Time-Dependent Field Gradient. J Chem Phys. 1965; 42:288-92.
47. Andersson JLR, Skare S, Ashburner J. How to correct susceptibility distortions in spin-echo echo-planar images: application to diffusion tensor imaging. NeuroImage. 2003; 20(2):870-88. PMID: 14568458
48. Paxinos G, Huang XF, Toga AW. The rhesus monkey brain in stereotaxic coordinates. San Diego, CA: Academic Press; 2000. 163 p. p.
49. Schaefer S, McPhail T, Warren J. Image deformation using moving least squares. ACM Trans Graph. 2006; 25(3):533-40.
50. Tiddeman B. A general method for overlap control in image warping. Computers & Graphics. 2001; 25 (1):59-66.
51. Markovitz CD, Tang TT, Edge DP, Lim HH. Three-dimensional brain reconstruction of in vivo electrode tracks for neuroscience and neural prosthetic applications. Frontiers in Neural Circuits. 2012; 6(00039).
52. Keane M, Deyo S, Abosch A, Bajwa JA, Johnson MD. Improved spatial targeting with directionally segmented deep brain stimulation leads for treating essential tremor. Journal of neural engineering. 2012; 9(4):046005. doi: 10.1088/1741-2560/9/4/046005 PMID: 22732947
53. Jenkinson CF, Beckmann TE, Behrens MW, Woolrich MW, Smith SM. FSL. NeuroImage. 2012; 62:782-90. doi: 10.1016/j.neuroimage.2011.09.015 PMID: 21979382
54. Woolrich MW, Jbabdi S, Patenaude B, Chappell M, Makni S, Behrens T, et al. Bayesian analysis of neuroimaging data in FSL. NeuroImage. 2009; 45(1, Supplement 1):S173-S86. doi: 10.1016/j.neuroimage.2008.10.055 PMID: 19059349
55. Smith SM, Jenkinson M, Woolrich MW, Beckmann CF, Behrens TEJ, Johansen-Berg H, et al. Advances in functional and structural MR image analysis and implementation as FSL. NeuroImage. 2004; 23(S1):208-19.
56. Smith SM. Fast robust automated brain extraction. Hum Brain Mapp. 2002; 17(3):143-55. PMID: 12391568
57. Jenkinson M, Bannister P, Brady JM, Smith SM. Improved Optimisation for the Robust adn Accurate Linear Registration and Motion Correction of Brain Images. NeuroImage. 2002; 17(2):825-41. PMID: 12377157
58. Jenkinson M, Smith SM. A Global Optimisation Method for Robust Affine Registration of Brain Images. Medical Image Analysis. 2001; 5(2):143-56. PMID: 11516708
59. Greve DN, Fischl B. Accurate and robust brain image alignment using boundary-based registration. NeuroImage. 2009; 48(1):63-72 doi: 10.1016/j.neuroimage.2009.06.060 PMID: 19573611
60. Perrini P, Tiezzi G, Castagna M, Vannozzi R. Three-dimensional microsurgical anatomy of cerebellar peduncles. Neurosurgical Review. 2012:1-11.
61. Duvernoy HM, Vannson JL. Human brainstem vessels: Springer-Verlag Berlin; 1978.
62. Johnson MD, McIntyre CC. Quantifying the neural elements activated and inhibited by globus pallidus deep brain stimulation. J Neurophysiol. 2008; 100(5):2549-63. doi: 10.1152/jn.90372.2008 PMID: 18768645
63. Johnson MD, Zhang J, Ghosh D, McIntyre CC, Vitek JL. Neural targets for relieving parkinsonian rigidity and bradykinesia with pallidal deep brain stimulation. J Neurophysiol. 2012; 108(2):567-77. doi: 10.1152/jn.00039.2012 PMID: 22514292
64. Miocinovic S, Parent M, Butson CR, Hahn PJ, Russo GS, Vitek JL, et al. Computational analysis of subthalamic nucleus and lenticular fasciculus activation during therapeutic deep brain stimulation. J Neurophysiol. 2006; 96(3):1569-80. PMID: 16738214
65. Xu W, Miocinovic S, Zhang J, Baker KB, McIntyre CC, Vitek JL. Dissociation of motor symptoms during deep brain stimulation of the subthalamic nucleus in the region of the internal capsule. Experimental neurology. 2011; 228(2):294-7. Epub 2010/08/18. doi: 10.1016/j.expneurol.2010.08.007 PMID: 20713049
66. Ferraye MU, DebÛ B, Fraix V, Goetz L, Ardouin C, Yelnik J, et al. Effects of pedunculopontine nucleus area stimulation on gait disorders in Parkinson's disease. Brain. 2010; 133(1):205-14.
67. Kojima J, Yamaji Y, Matsumura M, Nambu A, Inase M, Tokuno H, et al. Excitotoxic lesions of the pedunculopontine tegmental nucleus produce contralateral hemiparkinsonism in the monkey. Neurosci Lett. 1997; 226(2):111-4. PMID: 9159502
68. Matsumura M, Kojima J. The role of the pedunculopontine tegmental nucleus in experimental parkinsonism in primates. Stereotactic and functional neurosurgery. 2001; 77:108-15. PMID: 12378066
69. Weinberger M, Hamani C, Hutchison W, Moro E, Lozano A, Dostrovsky J. Pedunculopontine nucleus microelectrode recordings in movement disorder patients. Experimental Brain Research. 2008; 188 (2):165-74. doi: 10.1007/s00221-008-1349-1 PMID: 18347783
70. Hosobuchi Y. Dorsal Periaqueductal Grey-Matter Stimulation in Humans. Pacing Clin Electrophysiol. 1987; 10(1):213-6. PMID: 2436181
71. Lim HH, Lenarz T, Anderson DJ, Lenarz M. The auditory midbrain implant: Effects of electrode location. Hearing Research. 2008; 242(1-2):74-85. doi: 10.1016/j.heares.2008.06.006 PMID: 18616993
72. Jenkinson N, Nandi D, Miall RC, Stein JF, Aziz TZ. Pedunculopontine nucleus stimulation improves akinesia in a Parkinsonian monkey. Neuroreport. 2004; 15(17):2621-4. PMID: 15570164
73. Mayer DJ, Wolfle TL, Akil H, Carder B, Liebeskind JC. Analgesia from Electrical Stimulation in the Brainstem of the Rat. Science. 1971; 174(4016):1351-254. PMID: 5167502
74. Mayer DJ, Liebeskind JC. Pain reduction by focal electrical stimulation of the brain: an anatomical and behavioral analysis. Brain research. 1974; 68:73-93. PMID: 4549764
75. Ganser KA, Dickhaus H, Metzner R, Wirtz CR. A deformable digital brain atlas system according to Talairach and Tournoux. Medical Image Analysis. 2004; 8(1):3-22. PMID: 14644143
76. Sadikot AF, Chakravarty MM, Bertrand G, Rymar VV, Al-Subaie F, Collins LD. Creation of computerized 3D MRI-integrated atlases of the human basal ganglia and thalamus. Frontiers in Systems Neuroscience. 2011; 5(00071).
77. St-Jean P, Sadikot AF, Collins L, Clonda D, Kasrai R, Evans AC, et al. Automated atlas integration and interactive three-dimensional visualization tools for planning and guidance in functional neurosurgery. IEEE Transactions on Medical Imaging. 1998; 17(5):672-80. PMID: 9874291
78. Bohm C, Greitz T, Kingsley D, Berggren BM, Olsson L. Adjustable computerized stereotaxic brain atlas for transmission and emission tomography. American Journal of Neuroradiology. 1983; 4(3):731-3. PMID: 6410844
79. Evans AC, Beil S, Marrett S, Thompson CJ, Hakim A. Anatomical-Functional Correlation Using an Adjustable MRI-Based Region of Interest Atlas with Positron Emission Tomography. J Cereb Blood Flow Metab. 1988; 8(4):513-30. PMID: 3260594
80. Dann R, Hoford J, Kovacic S, Reivich M, Bajcsy R. Three-Dimensional Computerized Brain Atlas for Elastic Matching: Creation and Initial Evaluation. Proc SPIE 1988;0914:600-8.
81. Sandor S, Leahy R, editors. Matching deformable atlas models to preprocessed magnetic resonance brain images. IEEE International Conference; 1994 13-16 Nov 1994; Austin, TX: IEEE.
82. Gee J, Reivich M, Bilaniuk L, Hackney DZ, R, Kovacic S, Bajcsy R. Evaluation of multiresolution elastic matching using MRI data. SPIE. 1991; 1445:226-34.
83. Chaturvedi A, Foutz TJ, McIntyre CC. Current steering to activate targeted neural pathways during deep brain stimulation of the subthalamic region. Brain stimulation. 2012; 5(3):369-77. doi: 10.1016/j.brs.2011.05.002 PMID: 22277548
84. Butson CR, McIntyre CC. Current Steering to Control the Volume of Tissue Activated During Deep Brain Stimulation. Brain stimulation. 2008; 1(1):7-15. doi: 10.1016/j.brs.2007.08.004 PMID: 19142235
85. Paxinos G. The Rhesus Monkey Brain: In Stereotaxic Coordinates: Elsevier/Academic Press; 2009. doi: 10.1007/s12021-008-9039-5 PMID: 19145492
86. Wang H, Zhu J, Reuter M, Vinke LN, Yendiki A, Boas DA, et al. Cross-validation of serial optical coherence scanning and diffusion tensor imaging: A study on neural fiber maps in human medulla oblongata. NeuroImage. 2014; 100:395-404. doi: 10.1016/j.neuroimage.2014.06.032 PMID: 24954840
87. Miocinovic S, Zhang J, Xu W, Russo GS, Vitek JL, McIntyre CC. Stereotactic neurosurgical planning, recording, and visualization for deep brain stimulation in non-human primates. Journal of neuroscience methods. 2007; 162(1-2):32-41. PMID: 17368560