Microvascular obstruction and endothelial activation are independently associated with the clinical manifestations of severe falciparum malaria in adults: An observational study

BMC Medicine

Volumn 13, Issue 1, 2015, Pages

  Hanson, Josh ^a,b   Lee, Sue J ^a,c   Hossain, Amir M ^d   Anstey, Nicholas M ^b   Charunwatthana, Prakaykaew ^a   Maude, Richard J ^a,c   Kingston, Hugh W ^a,b   Mishra, Saroj K ^e   Mohanty, Sanjib ^e   Plewes, Katherine ^a   Piera, Kim ^b   Hassan, Mahtab U ^d   Ghose, Aniruddha ^d   Faiz, M Aniruddha ^a,f,g   White, Nicholas J ^a,c   Day, Nicholas P ^a,c   Dondorp, Arjen M ^a,c  

^a MAHIDOL UNIVERSITY   (Thailand)

^b MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d CHITTAGONG MEDICAL COLLEGE HOSPITAL   (Bangladesh)

^e Ispat Hospital   (India)

^f Centre for Specialized Care and Research   (Bangladesh)

^g Dev Care Foundation   (Bangladesh)

Author keywords

Endothelial dysfunction; Falciparum malaria; Microcirculation; Pathophysiology

Indexed keywords

ANGIOPOIETIN 2; CREATININE; HEMOGLOBIN; LACTIC ACID; VASCULOTROPIN;

ARTERIAL OXYGEN SATURATION; ARTERIAL PRESSURE; ARTICLE; BLOOD FLOW; CELL ACTIVATION; CREATININE BLOOD LEVEL; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDOTHELIAL DYSFUNCTION; ENDOTHELIUM CELL; HUMAN; LACTATE BLOOD LEVEL; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MICROCIRCULATION; MICROVASCULAR OBSTRUCTION; NONHUMAN; OBSERVATIONAL STUDY; PROTEIN BLOOD LEVEL; VASCULAR DISEASE; ADULT; BLOOD; CAPILLARY; COMPLICATION; FEMALE; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY;

ADULT; CAPILLARIES; ENDOTHELIAL CELLS; FEMALE; HUMANS; MALARIA, FALCIPARUM; MALE; MICROCIRCULATION; MIDDLE AGED;

EID: 84930627191     PISSN: None     EISSN: 17417015     Source Type: Journal    
DOI: 10.1186/s12916-015-0365-9     Document Type: Article

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