-
1
-
-
70849099495
-
The extracellular matrix: Not just pretty fibrils
-
Hynes RO. The extracellular matrix: not just pretty fibrils. Science. 2009; 26:1216-1219.
-
(2009)
Science
, vol.26
, pp. 1216-1219
-
-
Hynes, R.O.1
-
2
-
-
84863975330
-
Overview of the matrisome-an inventory of extracellular matrix constituents and functions
-
Hynes RO, Naba A. Overview of the matrisome-an inventory of extracellular matrix constituents and functions. Cold Spring Harb Perspect Biol. 2012;4:a004903.
-
(2012)
Cold Spring Harb Perspect Biol
, vol.4
, pp. a004903
-
-
Hynes, R.O.1
Naba, A.2
-
3
-
-
84884709908
-
Extracellular matrix components in breast cancer progression and metastasis
-
Oskarsson T. Extracellular matrix components in breast cancer progression and metastasis. Breast. 2013;22(suppl 2): S66-S72.
-
(2013)
Breast
, vol.22
, pp. S66-S72
-
-
Oskarsson, T.1
-
4
-
-
34848863979
-
Impact of the non-cellular tumor microenvironment on metastasis: Potential therapeutic and imaging opportunities
-
Cretu A, Brooks PC. Impact of the non-cellular tumor microenvironment on metastasis: potential therapeutic and imaging opportunities. J Cell Physiol. 2007;213:391-402.
-
(2007)
J Cell Physiol
, vol.213
, pp. 391-402
-
-
Cretu, A.1
Brooks, P.C.2
-
5
-
-
0034647922
-
Distinct antitumor properties of a type IV collagen domain derived from basement membrane
-
Maeshima Y, Colorado PC, Torre A, et al. Distinct antitumor properties of a type IV collagen domain derived from basement membrane. J Biol Chem. 2000;275:21340-21348.
-
(2000)
J Biol Chem
, vol.275
, pp. 21340-21348
-
-
Maeshima, Y.1
Colorado, P.C.2
Torre, A.3
-
6
-
-
0033979905
-
Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth
-
Kamphaus GD, et al. Canstatin, a novel matrix-derived inhibitor of angiogenesis and tumor growth. J Biol Chem. 2000;275:1209-1215.
-
(2000)
J Biol Chem
, vol.275
, pp. 1209-1215
-
-
Kamphaus, G.D.1
-
7
-
-
77950931419
-
Matrix metalloproteinases: Regulators of the tumor microenvironment
-
Kessenbrock K, Plaks V, Werb Z. Matrix metalloproteinases: regulators of the tumor microenvironment. Cell. 2010;141:52-67.
-
(2010)
Cell
, vol.141
, pp. 52-67
-
-
Kessenbrock, K.1
Plaks, V.2
Werb, Z.3
-
8
-
-
79953163995
-
Proteolytic networks in cancer
-
Mason SD, Joyce JA. Proteolytic networks in cancer. Trends Cell Biol. 2011;21:228-237.
-
(2011)
Trends Cell Biol
, vol.21
, pp. 228-237
-
-
Mason, S.D.1
Joyce, J.A.2
-
9
-
-
79955828776
-
Stromal biology and therapy in pancreatic cancer
-
Neesse A, Michl P, Frese KK, et al. Stromal biology and therapy in pancreatic cancer. Gut. 2011;60:861-868.
-
(2011)
Gut
, vol.60
, pp. 861-868
-
-
Neesse, A.1
Michl, P.2
Frese, K.K.3
-
10
-
-
78349256721
-
The role of the microenvironment in mammary gland development and cancer
-
Polyak K, Kalluri R. The role of the microenvironment in mammary gland development and cancer. Cold Spring Harb Perspect Biol. 2010;2:a003244.
-
(2010)
Cold Spring Harb Perspect Biol
, vol.2
, pp. a003244
-
-
Polyak, K.1
Kalluri, R.2
-
11
-
-
84864943044
-
Why the stroma matters in breast cancer: Insights into breast cancer patient outcomes through the examination of stromal biomarkers
-
Conklin MW, Keely PJ. Why the stroma matters in breast cancer: insights into breast cancer patient outcomes through the examination of stromal biomarkers. Cell Adh Migr. 2012;6:249-260.
-
(2012)
Cell Adh Migr
, vol.6
, pp. 249-260
-
-
Conklin, M.W.1
Keely, P.J.2
-
12
-
-
84923217987
-
The impact of tumor stroma on drug response in breast cancer
-
Dittmer J, Leyh B. The impact of tumor stroma on drug response in breast cancer. Semin Cancer Biol. 2015;31C:3-15.
-
(2015)
Semin Cancer Biol
, vol.31 C
, pp. 3-15
-
-
Dittmer, J.1
Leyh, B.2
-
13
-
-
84934441514
-
Radiotherapy and the tumor microenvironment: Mutual influence and clinical implications
-
Thompson RF, Maity A. Radiotherapy and the tumor microenvironment: mutual influence and clinical implications. Adv Exp Med Biol. 2014;772:147-165.
-
(2014)
Adv Exp Med Biol
, vol.772
, pp. 147-165
-
-
Thompson, R.F.1
Maity, A.2
-
14
-
-
0024708518
-
The distribution of secondary growths in cancer of the breast 1889
-
Paget S. The distribution of secondary growths in cancer of the breast. 1889. Cancer Metastasis Rev. 1989;8:98-101.
-
(1989)
Cancer Metastasis Rev
, vol.8
, pp. 98-101
-
-
Paget, S.1
-
15
-
-
79953300698
-
The seed and soil hypothesis revisited-The role of tumor-stroma interactions in metastasis to different organs
-
Langley RR, Fidler IJ. The seed and soil hypothesis revisited-the role of tumor-stroma interactions in metastasis to different organs. Int J Cancer. 2011;128:2527-2535.
-
(2011)
Int J Cancer
, vol.128
, pp. 2527-2535
-
-
Langley, R.R.1
Fidler, I.J.2
-
16
-
-
84928774156
-
The future of immune checkpoint therapy
-
Sharma P, Allison JP. The future of immune checkpoint therapy. Science. 2015;348:56-61.
-
(2015)
Science
, vol.348
, pp. 56-61
-
-
Sharma, P.1
Allison, J.P.2
-
17
-
-
84883184920
-
Real time dynamic imaging and current targeted therapies in the war on cancer: A new paradigm
-
Paulmurugan R, Oronsky B, Brouse CF, et al. Real time dynamic imaging and current targeted therapies in the war on cancer: a new paradigm. Theranostics. 2013;3:437-447.
-
(2013)
Theranostics
, vol.3
, pp. 437-447
-
-
Paulmurugan, R.1
Oronsky, B.2
Brouse, C.F.3
-
18
-
-
84934438418
-
Imaging angiogenesis, inflammation, and metastasis in the tumor microenvironment with magnetic resonance imaging
-
Serres S, O'Brien ER, Sibson NR. Imaging angiogenesis, inflammation, and metastasis in the tumor microenvironment with magnetic resonance imaging. Adv Exp Med Biol. 2014;772:263-283.
-
(2014)
Adv Exp Med Biol
, vol.772
, pp. 263-283
-
-
Serres, S.1
O'Brien, E.R.2
Sibson, N.R.3
-
20
-
-
79960835510
-
Hypoxic stress and cancer: Imaging the axis of evil in tumor metastasis
-
Avni R, Cohen B, Neeman M. Hypoxic stress and cancer: imaging the axis of evil in tumor metastasis. NMR Biomed. 2011;24:569-581.
-
(2011)
NMR Biomed
, vol.24
, pp. 569-581
-
-
Avni, R.1
Cohen, B.2
Neeman, M.3
-
22
-
-
84902163612
-
Magnetic resonance imaging of the tumor microenvironment in radiotherapy: Perfusion, hypoxia, and metabolism
-
Matsuo M, Matsumoto S, Mitchell JB, et al. Magnetic resonance imaging of the tumor microenvironment in radiotherapy: perfusion, hypoxia, and metabolism. Semin Radiat Oncol. 2014;24:210-217.
-
(2014)
Semin Radiat Oncol
, vol.24
, pp. 210-217
-
-
Matsuo, M.1
Matsumoto, S.2
Mitchell, J.B.3
-
23
-
-
84924072284
-
F-18 Fluoromisonidazole for imaging tumor hypoxia: Imaging the microenvironment for personalized cancer therapy
-
Rajendran JG, Krohn KA. F-18 Fluoromisonidazole for imaging tumor hypoxia: imaging the microenvironment for personalized cancer therapy. Semin Nucl Med. 2015;45:151-162.
-
(2015)
Semin Nucl Med
, vol.45
, pp. 151-162
-
-
Rajendran, J.G.1
Krohn, K.A.2
-
25
-
-
80455126007
-
Bhujwalla ZM.MRI of metastasis-permissive microenvironments
-
Penet MF, Chen Z, Bhujwalla ZM.MRI of metastasis-permissive microenvironments. Future Oncol. 2011;7:1269-1284.
-
(2011)
Future Oncol
, vol.7
, pp. 1269-1284
-
-
Penet, M.F.1
Chen, Z.2
-
26
-
-
79952154676
-
Metabolic tumor imaging using magnetic resonance spectroscopy
-
Glunde K, Bhujwalla ZM. Metabolic tumor imaging using magnetic resonance spectroscopy. Semin Oncol. 2011;38:26-41.
-
(2011)
Semin Oncol
, vol.38
, pp. 26-41
-
-
Glunde, K.1
Bhujwalla, Z.M.2
-
27
-
-
44149084706
-
Molecular and functional MRI of the tumor microenvironment
-
Penet MF, Glunde K, Jacobs MA, et al. Molecular and functional MRI of the tumor microenvironment. J NuclMed. 2008;49:687-690.
-
(2008)
J Nucl Med
, vol.49
, pp. 687-690
-
-
Penet, M.F.1
Glunde, K.2
Jacobs, M.A.3
-
28
-
-
84859992000
-
Multi-color palette of fluorescent proteins for imaging the tumor microenvironment of orthotopic tumorgraft mouse models of clinical pancreatic cancer specimens
-
SuetsuguA, KatzM, Fleming J, et al.Multi-color palette of fluorescent proteins for imaging the tumor microenvironment of orthotopic tumorgraft mouse models of clinical pancreatic cancer specimens. J Cell Biochem. 2012;113:2290-2295.
-
(2012)
J Cell Biochem
, vol.113
, pp. 2290-2295
-
-
Suetsugu, A.1
Katz, M.2
Fleming, J.3
-
29
-
-
33846293595
-
Probing the microenvironment of mammary tumors using multiphoton microscopy
-
Sidani M, Wyckoff J, Xue C, et al. Probing the microenvironment of mammary tumors using multiphoton microscopy. J Mammary Gland Biol Neoplasia. 2013;11:151-163.
-
(2013)
J Mammary Gland Biol Neoplasia
, vol.11
, pp. 151-163
-
-
Sidani, M.1
Wyckoff, J.2
Xue, C.3
-
30
-
-
77958105047
-
Intravital imaging of anti-tumor immune response and the tumor microenvironment
-
Zal T, Chodaczek G. Intravital imaging of anti-tumor immune response and the tumor microenvironment. Semin Immunopathol. 2010;32:305-317.
-
(2010)
Semin Immunopathol
, vol.32
, pp. 305-317
-
-
Zal, T.1
Chodaczek, G.2
-
31
-
-
84887217383
-
Live imaging of drug responses in the tumor microenvironment in mouse models of breast cancer
-
Nakasone ES, Askautrud HA, Egeblad M. Live imaging of drug responses in the tumor microenvironment in mouse models of breast cancer. J Vis Exp. 2013: e50088.
-
(2013)
J Vis Exp
, pp. e50088
-
-
Nakasone, E.S.1
Askautrud, H.A.2
Egeblad, M.3
-
32
-
-
84912569285
-
Multiparametric classification links tumor microenvironments with tumor cell phenotype
-
Gligorijevic B, Bergman A, Condeelis J. Multiparametric classification links tumor microenvironments with tumor cell phenotype. PLoS Biol. 2014;12:e1001995.
-
(2014)
PLoS Biol
, vol.12
, pp. e1001995
-
-
Gligorijevic, B.1
Bergman, A.2
Condeelis, J.3
-
33
-
-
84859820567
-
Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance
-
Nakasone ES, Askautrud HA, Kees T, et al. Imaging tumor-stroma interactions during chemotherapy reveals contributions of the microenvironment to resistance. Cancer Cell. 2012;21:488-503.
-
(2012)
Cancer Cell
, vol.21
, pp. 488-503
-
-
Nakasone, E.S.1
Askautrud, H.A.2
Kees, T.3
-
34
-
-
84858298134
-
Reviewof functional/anatomical imaging in oncology
-
Histed SN, LindenbergML, Mena E, et al. Reviewof functional/anatomical imaging in oncology. Nucl Med Commun. 2012;33:349-361.
-
(2012)
Nucl Med Commun
, vol.33
, pp. 349-361
-
-
Histed, S.N.1
Lindenbergml Mena, E.2
-
35
-
-
79960833882
-
Exploiting the tumor microenvironment for theranostic imaging
-
Stasinopoulos I, Penet MF, Chen Z, et al. Exploiting the tumor microenvironment for theranostic imaging. NMR Biomed. 2011;24:636-647.
-
(2011)
NMR Biomed
, vol.24
, pp. 636-647
-
-
Stasinopoulos, I.1
Penet, M.F.2
Chen, Z.3
-
36
-
-
0022891340
-
Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
-
Dvorak HF. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl JMed. 1986;315:1650-1659.
-
(1986)
N Engl JMed
, vol.315
, pp. 1650-1659
-
-
Dvorak, H.F.1
-
37
-
-
84902469661
-
Depletion of carcinomaassociated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival
-
Ozdemir BC, Pentcheva-Hoang T, Carstens JL, et al. Depletion of carcinomaassociated fibroblasts and fibrosis induces immunosuppression and accelerates pancreas cancer with reduced survival. Cancer Cell. 2014;25:719-734.
-
(2014)
Cancer Cell
, vol.25
, pp. 719-734
-
-
Ozdemir, B.C.1
Pentcheva-Hoang, T.2
Carstens, J.L.3
-
38
-
-
84902435628
-
Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma
-
Rhim AD, Oberstein PE, Thomas DH, et al. Stromal elements act to restrain, rather than support, pancreatic ductal adenocarcinoma. Cancer Cell. 2014;25:735-747.
-
(2014)
Cancer Cell
, vol.25
, pp. 735-747
-
-
Rhim, A.D.1
Oberstein, P.E.2
Thomas, D.H.3
-
39
-
-
84855912001
-
Pericyte depletion results in hypoxiaassociated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway
-
CookeVG, LeBleuVS, KeskinD, et al. Pericyte depletion results in hypoxiaassociated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway. Cancer Cell. 2012;21:66-81.
-
(2012)
Cancer Cell
, vol.21
, pp. 66-81
-
-
Cooke, V.G.1
Le Bleu, V.S.2
Keskin, D.3
-
40
-
-
84929142111
-
Targeting vascular pericytes in hypoxic tumors increases lungmetastasis via angiopoietin-2
-
KeskinD, Kim J, CookeVG, et al. Targeting vascular pericytes in hypoxic tumors increases lungmetastasis via angiopoietin-2. Cell Rep. 2015;10:1066-1081.
-
(2015)
Cell Rep
, vol.10
, pp. 1066-1081
-
-
Keskin, D.1
Kim, J.2
Cooke, V.G.3
-
41
-
-
84891111855
-
Strategies to increase drug penetration in solid tumors
-
Choi IK, Strauss R, Richter M, et al. Strategies to increase drug penetration in solid tumors. Front Oncol. 2013;3:193.
-
(2013)
Front Oncol
, vol.3
, pp. 193
-
-
Choi, I.K.1
Strauss, R.2
Richter, M.3
|