-
1
-
-
84930594235
-
-
World Health Organization. Hepatitis C. September 10
-
World Health Organization. Hepatitis C. http://www.who.int/mediacentre/factsheets/fs164/en/Accessed September 10, 2014.
-
(2014)
-
-
-
2
-
-
84857144025
-
The increasing burden of mortality from viral hepatitis in the United States between 1999 and 2007
-
,,, et al.. ;:-
-
Ly KN,Xing J,Klevens RM, et al.The increasing burden of mortality from viral hepatitis in the United States between 1999 and 2007.Ann Intern Med. 2012;156:271-278
-
(2012)
Ann Intern Med
, vol.156
, pp. 271-278
-
-
Ly, K.N.1
Xing, J.2
Klevens, R.M.3
-
3
-
-
0035934568
-
Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial
-
Manns MP,Mchutchison JG,Gordon SC,Rustgi VK,Shiffman M,Reindollar R.Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial.Lancet. 2001;358:958-965
-
(2001)
Lancet
, vol.358
, pp. 958-965
-
-
Manns, M.P.1
Mchutchison, J.G.2
Gordon, S.C.3
Rustgi, V.K.4
Shiffman, M.5
Reindollar, R.6
-
4
-
-
0037179698
-
Pedinterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection
-
,,, et al.. ;:-
-
Fried M,Shiffman M,Reddy R, et al.Pedinterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection.N Engl J Med. 2002;347:975-982
-
(2002)
N Engl J Med
, vol.347
, pp. 975-982
-
-
Fried, M.1
Shiffman, M.2
Reddy, R.3
-
5
-
-
79959438789
-
Telaprevir for previously untreated chronic hepatitis C virus infection
-
,,, et al.. ;:-
-
Jacobson I,Mchutchison J,Dusheiko G, et al.Telaprevir for previously untreated chronic hepatitis C virus infection.N Engl J Med. 2011;364:2405-2416
-
(2011)
N Engl J Med
, vol.364
, pp. 2405-2416
-
-
Jacobson, I.1
Mchutchison, J.2
Dusheiko, G.3
-
6
-
-
79953173221
-
Boceprevir for untreated chronic HCV genotype 1 infections
-
Poordad F,McCone J,Bacon B,Bruno S,Manns M,Sulkowski M.Boceprevir for untreated chronic HCV genotype 1 infections.N Engl J Med. 2011;364:1195-1206
-
(2011)
N Engl J Med
, vol.364
, pp. 1195-1206
-
-
Poordad, F.1
McCone, J.2
Bacon, B.3
Bruno, S.4
Manns, M.5
Sulkowski, M.6
-
7
-
-
79953176289
-
Boceprevir for previously treated chronic HCV genotype 1 infection
-
Bacon B,Gordon S,Lawitz E,Marcellin P,Vierling J,Zeuzem S.Boceprevir for previously treated chronic HCV genotype 1 infection.N Engl J Med. 2011;364:1207-1217
-
(2011)
N Engl J Med
, vol.364
, pp. 1207-1217
-
-
Bacon, B.1
Gordon, S.2
Lawitz, E.3
Marcellin, P.4
Vierling, J.5
Zeuzem, S.6
-
8
-
-
79959381354
-
Telaprevir for retreatment of HCV infection
-
Zeuzem S,Andreone P,Pol S,Lawitz E,Diago M,Roberts S.Telaprevir for retreatment of HCV infection.N Engl J Med. 2011;364:2417-2428
-
(2011)
N Engl J Med
, vol.364
, pp. 2417-2428
-
-
Zeuzem, S.1
Andreone, P.2
Pol, S.3
Lawitz, E.4
Diago, M.5
Roberts, S.6
-
9
-
-
84882908504
-
Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French Early Access Programme (ANRS CO20-CUPIC): NCT01514890
-
,,, et al.. ;:-
-
Hézode C,Fontaine H,Dorival C, et al.Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French Early Access Programme (ANRS CO20-CUPIC): NCT01514890.J Hepatol. 2013;59:434-441
-
(2013)
J Hepatol
, vol.59
, pp. 434-441
-
-
Hézode, C.1
Fontaine, H.2
Dorival, C.3
-
10
-
-
84930594236
-
-
AASLD/IDSA/IAS–USA. Recommendations for testing, managing, and treating hepatitis C. Accessed December 20, 2014
-
AASLD/IDSA/IAS–USA. Recommendations for testing, managing, and treating hepatitis C. http://www.hcvguidelines.org. Accessed December 20, 2014.
-
-
-
-
11
-
-
84930594237
-
-
European Association for the Study of the Liver. Recommendations on treatment of hepatitis C. Accessed December 20, 2014
-
European Association for the Study of the Liver. Recommendations on treatment of hepatitis C. http://www.easl.eu/assets/application/files/easl_recommendations_hcv_2014_full.pdf. Accessed December 20, 2014.
-
-
-
-
12
-
-
84930594238
-
-
Janssen Inc.Galexos (simeprevir) product monograph. Accessed February 21, 2015
-
Janssen Inc.Galexos (simeprevir) product monograph. http://www.janssen.ca. Accessed February 21, 2015.
-
-
-
-
13
-
-
84930594239
-
-
Janssen Inc.Olysio (simeprevir) prescribing information. Accessed February 21, 2015
-
Janssen Inc.Olysio (simeprevir) prescribing information. https://www.olysio.com/shared/product/olysio/prescribing-information.pdf. Accessed February 21, 2015.
-
-
-
-
14
-
-
84892565026
-
Pharmacokinetics of simeprevir (TMC435) in volunteers with moderate or severe hepatic impairment
-
Ouwerkerk-Mahadevan S,Simion A,Spittaels K,Beumont-Mauviel M.Pharmacokinetics of simeprevir (TMC435) in volunteers with moderate or severe hepatic impairment.J Hepatol. 2013;58:S365
-
(2013)
J Hepatol
, vol.58
, pp. 365
-
-
Ouwerkerk-Mahadevan, S.1
Simion, A.2
Spittaels, K.3
Beumont-Mauviel, M.4
-
15
-
-
84930594240
-
Summary of pharmacokinetic drug-drug interactions for simeprevir (TMC435), a hepatitis C virus NS3/4A inhibitor
-
,,,.; Brussels, Belgium;.
-
Ouwerkerk-Mahadevan S,Simion A,Peeters M,Beaumont-Mauvier M.Summary of pharmacokinetic drug-drug interactions for simeprevir (TMC435), a hepatitis C virus NS3/4A inhibitor.Abstract presented at: 14th European AIDs Conference (EACS); Brussels, Belgium;.
-
Abstract presented at: 14th European AIDs Conference (EACS)
-
-
Ouwerkerk-Mahadevan, S.1
Simion, A.2
Peeters, M.3
Beaumont-Mauvier, M.4
-
16
-
-
45249121177
-
Drugs behave as substrates, inhibitors and inducers of human cytochrome P450
-
Zhou S.Drugs behave as substrates, inhibitors and inducers of human cytochrome P450.Curr Drug Metab. 2008;9:310-322
-
(2008)
Curr Drug Metab
, vol.9
, pp. 310-322
-
-
Zhou, S.1
-
17
-
-
84872218656
-
Evaluation of metabolic interactions for TMC435 via cytochrome P450 enzymes in healthy volunteers
-
Sekar V,Verloes R,Meyvisch P,Spittaels K,Akuma SH,De Smedt G.Evaluation of metabolic interactions for TMC435 via cytochrome P450 enzymes in healthy volunteers.J Hepatol. 2010;52:S416
-
(2010)
J Hepatol
, vol.52
, pp. 416
-
-
Sekar, V.1
Verloes, R.2
Meyvisch, P.3
Spittaels, K.4
Akuma, S.H.5
De Smedt, G.6
-
18
-
-
84930594241
-
-
Gilead Sciences. Sovaldi (sofosbuvir) product monograph. Accessed February 21, 2015
-
Gilead Sciences. Sovaldi (sofosbuvir) product monograph. http://www.gilead.ca/pdf/ca/sovaldi_pm_english.pdf. Accessed February 21, 2015.
-
-
-
-
19
-
-
84904507580
-
Sofosbuvir: a nucleotide NS5B inhibitor for the treatment of chronic hepatitis C infection
-
Rose L,Bias TE,Mathias CB,Trooskin SB,Fong JJ.Sofosbuvir: a nucleotide NS5B inhibitor for the treatment of chronic hepatitis C infection.Ann Pharmacother. 2014;48:1019-1029
-
(2014)
Ann Pharmacother
, vol.48
, pp. 1019-1029
-
-
Rose, L.1
Bias, T.E.2
Mathias, C.B.3
Trooskin, S.B.4
Fong, J.J.5
-
20
-
-
84918826854
-
The effect of renal impairment and end stage renal disease on the single-dose pharmacokinetics of PSI-7977
-
,,, et al.; Barcelona, Spain;.
-
Cornpropst M,Denning J,Clemons D, et al.The effect of renal impairment and end stage renal disease on the single-dose pharmacokinetics of PSI-7977.Abstract presented at: 47th Annual Meeting of the European Association for the Study of the Liver (EASL); Barcelona, Spain;.
-
Abstract presented at: 47th Annual Meeting of the European Association for the Study of the Liver (EASL)
-
-
Cornpropst, M.1
Denning, J.2
Clemons, D.3
-
21
-
-
84872045267
-
The effect of hepatic impairment on the safety, pharmacokinetics, and antiviral activity of GS-7977 in hepatitis C infected subjects treated for seven days
-
,,, et al.. ;:-
-
Lawitz E,Rodriguez-Torres M,Cornpropst M, et al.The effect of hepatic impairment on the safety, pharmacokinetics, and antiviral activity of GS-7977 in hepatitis C infected subjects treated for seven days.J Hepatol. 2012;56:S445-S446
-
(2012)
J Hepatol
, vol.56
, pp. 445-446
-
-
Lawitz, E.1
Rodriguez-Torres, M.2
Cornpropst, M.3
-
22
-
-
84902481487
-
Sofosbuvir and ribavirin for the treatment of chronic HCV with cirrhosis and portal hypertension with and without decompensation: early virologic response and safety
-
,,, et al.. ;:
-
Afdhal N,Everson G,Calleja J, et al.Sofosbuvir and ribavirin for the treatment of chronic HCV with cirrhosis and portal hypertension with and without decompensation: early virologic response and safety.J Hepatol. 2014;60:S28
-
(2014)
J Hepatol
, vol.60
, pp. 28
-
-
Afdhal, N.1
Everson, G.2
Calleja, J.3
-
23
-
-
84930594243
-
-
Foster City, CA: ; :, Gilead Sciences Inc
-
Foster City, CA: Gilead Sciences Inc; 2014:
-
(2014)
-
-
-
24
-
-
84938310727
-
Effect of food and acid reducing agents on the relative bioavailability and pharmacokinetics of ledipasvir/sofosbuvir fixed dose combination tablet
-
,,,,,.; Washington, DC;.
-
German P,Yang J,West S,Han L,Sajwani K,Mathias A.Effect of food and acid reducing agents on the relative bioavailability and pharmacokinetics of ledipasvir/sofosbuvir fixed dose combination tablet.Abstract presented at: 15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy; Washington, DC;.
-
Abstract presented at: 15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy
-
-
German, P.1
Yang, J.2
West, S.3
Han, L.4
Sajwani, K.5
Mathias, A.6
-
25
-
-
84896125632
-
The pharmacokinetics of ledipasvir, an HCV specific NS5A inhibitor in HCV-uninfected subjects with moderate and severe hepatic impairment
-
,,, et al.. ;:
-
German P,Mathias A,Yang J, et al.The pharmacokinetics of ledipasvir, an HCV specific NS5A inhibitor in HCV-uninfected subjects with moderate and severe hepatic impairment.Hepatology. 2013;58:432A
-
(2013)
Hepatology
, vol.58
, pp. 432
-
-
German, P.1
Mathias, A.2
Yang, J.3
-
26
-
-
84930594245
-
-
Middlesex, UK: ; -., Bristol-Myers Squibb
-
Middlesex, UK: Bristol-Myers Squibb; 1-76.
-
-
-
-
28
-
-
84930594247
-
-
European Medicines Agency. Summary on compassionate use for daclatasvir. Accessed February 21, 2015
-
European Medicines Agency. Summary on compassionate use for daclatasvir. http://www.ema.europa.eu/docs/en_GB/document_library/Other/2014/02/WC500160499.pdf. Accessed February 21, 2015.
-
-
-
-
29
-
-
84872230064
-
Single-dose pharmacokinetics of daclatasvir (DCV; BMS-790052) in subjects with hepatic impairment compared with healthy subjects
-
,,, et al.; San Francisco, CA;.
-
Bifano M,Sevinsky H,Persson A, et al.Single-dose pharmacokinetics of daclatasvir (DCV; BMS-790052) in subjects with hepatic impairment compared with healthy subjects.Abstract presented at: 62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); San Francisco, CA;.
-
Abstract presented at: 62nd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
-
-
Bifano, M.1
Sevinsky, H.2
Persson, A.3
-
30
-
-
84930594249
-
Daclatasvir, an HCV NS5A replication complex inhibitor, has minimal effect on pharmacokinetics of midazolam, a sensitive probe for cytochrome P450 3A4
-
,,,,.; Cambridge, MA;.
-
Bifano M,Sevinsky H,Stonier M,Jiang H,Bertz R.Daclatasvir, an HCV NS5A replication complex inhibitor, has minimal effect on pharmacokinetics of midazolam, a sensitive probe for cytochrome P450 3A4.Abstract presented at: 8th International Workshop in Clinical Pharmacology of Hepatitis Therapy; Cambridge, MA;.
-
Abstract presented at: 8th International Workshop in Clinical Pharmacology of Hepatitis Therapy
-
-
Bifano, M.1
Sevinsky, H.2
Stonier, M.3
Jiang, H.4
Bertz, R.5
-
31
-
-
84930594250
-
-
North Chicago, IL: ; :, Abbvie Corporation
-
North Chicago, IL: Abbvie Corporation; 2014:
-
(2014)
-
-
-
32
-
-
84928247694
-
Pharmacokinetics and safety of co-administered ABT-450 plus ritonavir (ABT 450/r), ABT-267 and ABT-333 as a single dose in subjects with normal hepatic function and in subjects with mild, moderate and severe hepatic impairment
-
,,, et al.; Boston, MA;.
-
Khatri A,Gaultier I,Menon R, et al.Pharmacokinetics and safety of co-administered ABT-450 plus ritonavir (ABT 450/r), ABT-267 and ABT-333 as a single dose in subjects with normal hepatic function and in subjects with mild, moderate and severe hepatic impairment.Abstract presented at: 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); Boston, MA;.
-
Abstract presented at: 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
-
-
Khatri, A.1
Gaultier, I.2
Menon, R.3
-
33
-
-
84942905653
-
ABT-450/ritonavir+ ombitasvir + dasabuvir: drug interactions mediated by transporters
-
,,, et al.; Washington, DC;.
-
Menon R,Badri P,Khatri A, et al.ABT-450/ritonavir+ ombitasvir + dasabuvir: drug interactions mediated by transporters.Abstract presented at: 15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy; Washington, DC;.
-
Abstract presented at: 15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy
-
-
Menon, R.1
Badri, P.2
Khatri, A.3
-
34
-
-
48249104628
-
Induction effects of ritonavir: implications for drug interactions
-
Foisy MM,Yakiwchuk EM,Hughes CA.Induction effects of ritonavir: implications for drug interactions.Ann Pharmacother. 2008;42:1048-1059
-
(2008)
Ann Pharmacother
, vol.42
, pp. 1048-1059
-
-
Foisy, M.M.1
Yakiwchuk, E.M.2
Hughes, C.A.3
-
35
-
-
0031751330
-
Ritonavir: clinical pharmacokinetics and interactions with other anti-HIV agents
-
Hsu A,Granneman GR,Bertz RJ,Laboratories A,Park A.Ritonavir: clinical pharmacokinetics and interactions with other anti-HIV agents.Clin Pharmacokinet. 1998;35:275-291
-
(1998)
Clin Pharmacokinet
, vol.35
, pp. 275-291
-
-
Hsu, A.1
Granneman, G.R.2
Bertz, R.J.3
Laboratories, A.4
Park, A.5
-
36
-
-
33644799276
-
Management of hepatitis C-infected liver transplant recipients at large North American centres: changes in recent years
-
,,, et al.. ;:-
-
Khalili M,Vardanian AJ,Hamerski CM, et al.Management of hepatitis C-infected liver transplant recipients at large North American centres: changes in recent years.Clin Transplant. 2005;20:1-9
-
(2005)
Clin Transplant
, vol.20
, pp. 1-9
-
-
Khalili, M.1
Vardanian, A.J.2
Hamerski, C.M.3
-
37
-
-
84909609695
-
Post-liver transplant hepatitis C virus recurrence: an unresolved thorny problem
-
Grassi A,Ballardini G.Post-liver transplant hepatitis C virus recurrence: an unresolved thorny problem.World J Gastroenterol. 2014;20:11095-11115
-
(2014)
World J Gastroenterol
, vol.20
, pp. 11095-11115
-
-
Grassi, A.1
Ballardini, G.2
-
38
-
-
0041831261
-
Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus
-
,,, et al.. ;:-
-
Hesselink DA,van Schaik RHN,van der Heiden IP, et al.Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus.Clin Pharmacol Ther. 2003;74:245-254
-
(2003)
Clin Pharmacol Ther
, vol.74
, pp. 245-254
-
-
Hesselink, D.A.1
van Schaik, R.H.N.2
van der Heiden, I.P.3
-
39
-
-
0034065402
-
Clinical pharmacokinetics monitoring of sirolimus and therapeutic drug monitoring of sirolimus
-
Macdonald A,Scarola J,Burke JT,Zimmerman JJ.Clinical pharmacokinetics monitoring of sirolimus and therapeutic drug monitoring of sirolimus.Clin Ther. 2000;22:B101-B121
-
(2000)
Clin Ther
, vol.22
, pp. 101-121
-
-
Macdonald, A.1
Scarola, J.2
Burke, J.T.3
Zimmerman, J.J.4
-
41
-
-
84901297850
-
No clinically significant pharmacokinetic drug-drug interactions between sofosbuvir (GS-7977) and the immunosuppressants, cyclosporine A or tacrolimus in healthy volunteers
-
,,, et al.; Boston, MA;.
-
Mathias A,Cornpropst M,Clemons D, et al.No clinically significant pharmacokinetic drug-drug interactions between sofosbuvir (GS-7977) and the immunosuppressants, cyclosporine A or tacrolimus in healthy volunteers.Abstract presented at: 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); Boston, MA;.
-
Abstract presented at: 63rd Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
-
-
Mathias, A.1
Cornpropst, M.2
Clemons, D.3
-
42
-
-
84923835679
-
Drug-drug interaction profile of the fixed-dose combination tablet ledipasvir/sofosbuvir
-
German P,Pang P,Fang L,Chung D,Mathias A.Drug-drug interaction profile of the fixed-dose combination tablet ledipasvir/sofosbuvir.Hepatology. 2014;60:1162A
-
(2014)
Hepatology
, vol.60
, pp. 1162
-
-
German, P.1
Pang, P.2
Fang, L.3
Chung, D.4
Mathias, A.5
-
43
-
-
84944551020
-
Ledipasvir/sofosbuvir with ribavirin for the treatment of HCV in patients with post transplant recurrence: preliminary results of a prospective, multicenter study
-
,,, et al.; Boston, MA;.
-
Reddy R,Everson G,Flamm S, et al.Ledipasvir/sofosbuvir with ribavirin for the treatment of HCV in patients with post transplant recurrence: preliminary results of a prospective, multicenter study.Abstract presented at: 65th Annual Meeting of the American Association for the Study of Liver Diseases; Boston, MA;.
-
Abstract presented at: 65th Annual Meeting of the American Association for the Study of Liver Diseases
-
-
Reddy, R.1
Everson, G.2
Flamm, S.3
-
44
-
-
84930594256
-
Daclatasvir pharmacokinetics in healthy subjects: no clinically-relevant drug-drug interactions with either cyclosporine or tacrolimus
-
,,,,,.; Washington, DC;.
-
Bifano M,Adamczyk R,Hwang C,Hamza K,Marion A,Bertz R.Daclatasvir pharmacokinetics in healthy subjects: no clinically-relevant drug-drug interactions with either cyclosporine or tacrolimus.Abstract presented at: 64th Annual Meeting of the American Association for the Stufy of Liver Diseases; Washington, DC;.
-
Abstract presented at: 64th Annual Meeting of the American Association for the Stufy of Liver Diseases
-
-
Bifano, M.1
Adamczyk, R.2
Hwang, C.3
Hamza, K.4
Marion, A.5
Bertz, R.6
-
45
-
-
84930594257
-
Pharmacokinetics, safety and tolerability of cyclosporine or tacrolimus following coadministration of ABT-450/r, ABT-267 and ABT-333 in healthy subjects [Abstract]
-
,,, et al.; 2014San Francisco, CA; 2014.
-
Badri P,Cohen D,Ding B, et al.Pharmacokinetics, safety and tolerability of cyclosporine or tacrolimus following coadministration of ABT-450/r, ABT-267 and ABT-333 in healthy subjects [Abstract].World Transplantation Congress; 2014San Francisco, CA; 2014.
-
World Transplantation Congress
-
-
Badri, P.1
Cohen, D.2
Ding, B.3
-
46
-
-
84930594258
-
Pharmacokinetics of cyclosporine and tacrolimus, following co-administration with the direct acting antiviral combination, ABT-450/r, ombitasvir and dasabuvir, in liver transplant patients with genotype-1 HCV infection
-
,,, et al.; Boston, MA;.
-
Badri P,Parikh A,Coakley E, et al.Pharmacokinetics of cyclosporine and tacrolimus, following co-administration with the direct acting antiviral combination, ABT-450/r, ombitasvir and dasabuvir, in liver transplant patients with genotype-1 HCV infection.Abstract presented at: 65th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD); Boston, MA;.
-
Abstract presented at: 65th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD)
-
-
Badri, P.1
Parikh, A.2
Coakley, E.3
-
47
-
-
84919360641
-
An interferon-free antiviral regimen for HCV after liver transplantation
-
,,, et al.. ;:-
-
Kwo PY,Mantry PS,Coakley E, et al.An interferon-free antiviral regimen for HCV after liver transplantation.N Engl J Med. 2014;37:2375-2382
-
(2014)
N Engl J Med
, vol.37
, pp. 2375-2382
-
-
Kwo, P.Y.1
Mantry, P.S.2
Coakley, E.3
-
48
-
-
27944433384
-
Prednisolone pharmacokinetics in the presence and absence of ritonavir after oral prednisone administration to healthy volunteers
-
Penzak SR,Formentini E,Alfaro RM,Long M,Natarajan V,Kovacs J.Prednisolone pharmacokinetics in the presence and absence of ritonavir after oral prednisone administration to healthy volunteers.J Acquir Immune Defic Syndr. 2005;40:573-580
-
(2005)
J Acquir Immune Defic Syndr
, vol.40
, pp. 573-580
-
-
Penzak, S.R.1
Formentini, E.2
Alfaro, R.M.3
Long, M.4
Natarajan, V.5
Kovacs, J.6
-
49
-
-
68749121062
-
Effect of coadministered HIV-protease inhibitors on tacrolimus and sirolimus blood concentrations in a kidney transplant recipient
-
Barau C,Blouin P,Creput C,Taburet AM,Durrbach A,Furlan V.Effect of coadministered HIV-protease inhibitors on tacrolimus and sirolimus blood concentrations in a kidney transplant recipient.Fundam Clin Pharmacol. 2009;23:423-425
-
(2009)
Fundam Clin Pharmacol
, vol.23
, pp. 423-425
-
-
Barau, C.1
Blouin, P.2
Creput, C.3
Taburet, A.M.4
Durrbach, A.5
Furlan, V.6
-
50
-
-
35748951286
-
Immunosuppressant pharmacokinetics and dosing modifications in HIV-1 infected liver and kidney transplant recipients
-
,,, et al.. ;:-
-
Frassetto LA,Browne M,Cheng A, et al.Immunosuppressant pharmacokinetics and dosing modifications in HIV-1 infected liver and kidney transplant recipients.Am J Transplant. 2007;7:2816-2820
-
(2007)
Am J Transplant
, vol.7
, pp. 2816-2820
-
-
Frassetto, L.A.1
Browne, M.2
Cheng, A.3
-
51
-
-
30144437514
-
Epidemiology of viral hepatitis and HIV co-infection
-
Alter MJ.Epidemiology of viral hepatitis and HIV co-infection.J Hepatol. 2006;44:6-9
-
(2006)
J Hepatol
, vol.44
, pp. 6-9
-
-
Alter, M.J.1
-
52
-
-
39649113866
-
The challenge of hepatitis C in the HIV-infected person
-
Thomas DL.The challenge of hepatitis C in the HIV-infected person.Annu Rev Med. 2008;59:473-485
-
(2008)
Annu Rev Med
, vol.59
, pp. 473-485
-
-
Thomas, D.L.1
-
54
-
-
84856869185
-
A review of drug interactions with boceprevir and telaprevir: implications for HIV and transplant patients
-
Wilby K,Greanya E,Ford J,Yoshida E,Partovi N.A review of drug interactions with boceprevir and telaprevir: implications for HIV and transplant patients.Ann Hepatol. 2012;11:179-185
-
(2012)
Ann Hepatol
, vol.11
, pp. 179-185
-
-
Wilby, K.1
Greanya, E.2
Ford, J.3
Yoshida, E.4
Partovi, N.5
-
55
-
-
84930594259
-
-
Department of Health and Human Services; Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents
-
Department of Health and Human Services; Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. http://aidsinfo.nih.gov/guidelines/html/1/adult-and-adolescent-treatment-guidelines/0.
-
-
-
-
56
-
-
84930594260
-
The pharmacokinetic interactions of HCV protease inhibitor TMC435 with RPV, TDF, EFV, or RAL in health volunteers
-
,,,.; Seattle, WA;.
-
Ouwerkerk-Mahadevan S,Sekar V,Peeters M,Beumont-Mauviel M.The pharmacokinetic interactions of HCV protease inhibitor TMC435 with RPV, TDF, EFV, or RAL in health volunteers.Abstract presented at: 19th Conference on Retroviruses and Opportunistic Infections (CROI); Seattle, WA;.
-
Abstract presented at: 19th Conference on Retroviruses and Opportunistic Infections (CROI)
-
-
Ouwerkerk-Mahadevan, S.1
Sekar, V.2
Peeters, M.3
Beumont-Mauviel, M.4
-
57
-
-
84878990586
-
The pharmacokinetic interactions of the HCV protease inhibitor simeprevir (TMC435) with HIV antiretroviral agents in healthy volunteers
-
,,,,.; Boston, MA;.
-
Ouwerkerk-Mahadevan S,Sekar V,Simion A,Peeters M,Beumont-Mauviel M.The pharmacokinetic interactions of the HCV protease inhibitor simeprevir (TMC435) with HIV antiretroviral agents in healthy volunteers.Abstract presented at: Infectious Diseases Society of America; Boston, MA;.
-
Abstract presented at: Infectious Diseases Society of America
-
-
Ouwerkerk-Mahadevan, S.1
Sekar, V.2
Simion, A.3
Peeters, M.4
Beumont-Mauviel, M.5
-
58
-
-
84891143311
-
Simeprevir (TMC435) plus peginterferon/ribavirin in patients co-infected with HCV genotype-1 and HIV-1: primary analysis of the C212 study
-
,,, et al.; Brussels, Belgium;.
-
Dieterich D,Rockstroh J,Orkin O, et al.Simeprevir (TMC435) plus peginterferon/ribavirin in patients co-infected with HCV genotype-1 and HIV-1: primary analysis of the C212 study.Abstract presented at: 14th European AIDs Conference (EACS); Brussels, Belgium;.
-
Abstract presented at: 14th European AIDs Conference (EACS)
-
-
Dieterich, D.1
Rockstroh, J.2
Orkin, O.3
-
59
-
-
84891143799
-
No clinically significant pharmacokinetic drug interactions between sofosbuvir (GS-7977) and HIV antiretrovirals Atripla (R), rilpivirine, darunavir/ritonavir, or raltegravir in healthy volunteers
-
,,, et al.; Boston, MA;.
-
Kirby B,Mathias A,Rossi S, et al.No clinically significant pharmacokinetic drug interactions between sofosbuvir (GS-7977) and HIV antiretrovirals Atripla (R), rilpivirine, darunavir/ritonavir, or raltegravir in healthy volunteers.Abstract presented at: 63rd Annual Meeting of the American Association for the Study of Liver Diseases; Boston, MA;.
-
Abstract presented at: 63rd Annual Meeting of the American Association for the Study of Liver Diseases
-
-
Kirby, B.1
Mathias, A.2
Rossi, S.3
-
60
-
-
77952584975
-
A phenotype-genotype approach to predicting CYP450 and P-glycoprotein drug interactions with the mixed inhibitor/inducer tipranavir/ritonavir
-
,,, et al.. ;:-
-
Dumond JB,Vourvahis M,Rezk NL, et al.A phenotype-genotype approach to predicting CYP450 and P-glycoprotein drug interactions with the mixed inhibitor/inducer tipranavir/ritonavir.Clin Pharmacol Ther. 2010;87:735-742
-
(2010)
Clin Pharmacol Ther
, vol.87
, pp. 735-742
-
-
Dumond, J.B.1
Vourvahis, M.2
Rezk, N.L.3
-
61
-
-
84913540202
-
Drug interactions between direct acting anti-HCV antivirals sofosbuvir and ledipasvir and HIV antiretrovirals
-
,,,,,.; Washington, DC;.
-
German P,Pang P,West S,Han L,Sajwani K,Mathias A.Drug interactions between direct acting anti-HCV antivirals sofosbuvir and ledipasvir and HIV antiretrovirals.Abstract presented at: 15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy; Washington, DC;.
-
Abstract presented at: 15th International Workshop on Clinical Pharmacology of HIV and Hepatitis Therapy
-
-
German, P.1
Pang, P.2
West, S.3
Han, L.4
Sajwani, K.5
Mathias, A.6
-
62
-
-
84891829801
-
Assessment of pharmacokinetic interactions of the HCV NS5A replication complex inhibitor daclatasvir with antiretroviral agents: ritonavir-boosted atazanavir, efavirenz and tenofovir
-
,,, et al.. ;:-
-
Bifano M,Hwang C,Oosterhuis B, et al.Assessment of pharmacokinetic interactions of the HCV NS5A replication complex inhibitor daclatasvir with antiretroviral agents: ritonavir-boosted atazanavir, efavirenz and tenofovir.Antivir Ther. 2013;18:931-940
-
(2013)
Antivir Ther
, vol.18
, pp. 931-940
-
-
Bifano, M.1
Hwang, C.2
Oosterhuis, B.3
-
63
-
-
84930594265
-
-
,,, et al. Miami, FL: ; :
-
Eley T,You X,Wang R, et alHIV DART. Miami, FL: ; 2014:
-
(2014)
HIV DART
-
-
Eley, T.1
You, X.2
Wang, R.3
-
64
-
-
84928334037
-
Drug-drug interactions of the direct acting antiviral regimen of ABT-450/r, ombitasvir and dasabuvir with HIV protease inhibitors
-
,,, et al.; Washington, DC;.
-
Khatri A,Wang T,Wang H, et al.Drug-drug interactions of the direct acting antiviral regimen of ABT-450/r, ombitasvir and dasabuvir with HIV protease inhibitors.Abstract presented at: 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC); Washington, DC;.
-
Abstract presented at: 54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
-
-
Khatri, A.1
Wang, T.2
Wang, H.3
-
65
-
-
84928334037
-
Drug-drug interactions of the direct acting antiviral regimen of ABT-450/r, ombitasvir and dasabuvir with emtricitabine + tenofovir, raltegravir, rilpivirine and efavirenz
-
,,, et al.; Washington, DC;.
-
Khatri A,Wang T,Wang H, et al.Drug-drug interactions of the direct acting antiviral regimen of ABT-450/r, ombitasvir and dasabuvir with emtricitabine + tenofovir, raltegravir, rilpivirine and efavirenz.54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC); Washington, DC;.
-
54th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC)
-
-
Khatri, A.1
Wang, T.2
Wang, H.3
-
66
-
-
40549127134
-
Effects of CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers
-
Abel S,Russell D,Taylor-Worth RJ,Ridgway CE,Muirhead GJ.Effects of CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers.Br J Clin Pharmacol. 2008;65:27-37
-
(2008)
Br J Clin Pharmacol
, vol.65
, pp. 27-37
-
-
Abel, S.1
Russell, D.2
Taylor-Worth, R.J.3
Ridgway, C.E.4
Muirhead, G.J.5
-
67
-
-
0034919632
-
Quantitative testing of liver function in relation to fibrosis in patients with chronic hepatitis B and C
-
Herold C,Heinz R,Niedobitek G,Schneider T,Eg H,Schuppan D.Quantitative testing of liver function in relation to fibrosis in patients with chronic hepatitis B and C.Liver. 2001;21:260-265
-
(2001)
Liver
, vol.21
, pp. 260-265
-
-
Herold, C.1
Heinz, R.2
Niedobitek, G.3
Schneider, T.4
Eg, H.5
Schuppan, D.6
|