Activation of tumour cell ECM degradation by thrombin-activated platelet membranes: potentially a P-selectin and GPIIb/IIIa-dependent process

Clinical and Experimental Metastasis

Volumn 32, Issue 5, 2015, Pages 495-505

  Pang, J H ^a,b   Coupland, L A ^a,c   Freeman, C ^a   Chong, B H ^d   Parish, Christopher R ^a  

^a Australian National University   (Australia)

^b Sirtex Medical Ltd   (Australia)

^c CANBERRA HOSPITAL   (Australia)

^d UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

GPIIb IIIa; Metastasis; P selectin; Platelets

Indexed keywords

FIBRINOGEN RECEPTOR; MATRIGEL; PADGEM PROTEIN; THROMBIN; HEMOSTATIC AGENT;

ANGIOGENESIS; ANIMAL CELL; ARTICLE; BREAST CARCINOMA; CELL FUNCTION; CONTROLLED STUDY; DEGRADATION; EXTRACELLULAR MATRIX; FEMALE; IN VITRO STUDY; LUNG METASTASIS; MOUSE; NONHUMAN; THROMBOCYTE MEMBRANE; THROMBOCYTE RICH PLASMA; TUMOR CELL; WOUND HEALING; ANIMAL; APOPTOSIS; CELL ADHESION; CELL MEMBRANE; CELL PROLIFERATION; DRUG EFFECTS; DRUG SCREENING; FLOW CYTOMETRY; HUMAN; LUNG TUMOR; METABOLISM; NEOPLASM; NUDE MOUSE; PATHOLOGY; SECONDARY; THROMBOCYTE; THROMBOCYTE ACTIVATION; TUMOR CELL CULTURE; TUMOR INVASION;

ANIMALS; APOPTOSIS; BLOOD PLATELETS; CELL ADHESION; CELL MEMBRANE; CELL PROLIFERATION; EXTRACELLULAR MATRIX; FEMALE; FLOW CYTOMETRY; HEMOSTATICS; HUMANS; LUNG NEOPLASMS; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; NEOPLASMS; P-SELECTIN; PLATELET ACTIVATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; THROMBIN; TUMOR CELLS, CULTURED; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84930572427     PISSN: 02620898     EISSN: 15737276     Source Type: Journal    
DOI: 10.1007/s10585-015-9722-5     Document Type: Article

References (24)

1. Gasic GJ, Gasic TB, Stewart CC (1968) Antimetastatic effects associated with platelet reduction. Proc Natl Acad Sci USA 61(1):46–52
2. Bendas G, Borsig L (2012) Cancer cell adhesion and metastasis: selectins, integrins, and the inhibitory potential of heparins. Int J Cell Biol 2012:676731. doi:10.1155/2012/676731
3. Gay LJ, Felding-Habermann B (2011) Contribution of platelets to tumour metastasis. Nat Rev Cancer 11(2):123–134
4. Janowska-Wieczorek A, Wysoczynski M, Kijowski J, Marquez-Curtis L, Machalinski B, Ratajczak J, Ratajczak MZ (2005) Microvesicles derived from activated platelets induce metastasis and angiogenesis in lung cancer. Int J Cancer 113(5):752–760
5. Janowska-Wieczorek A, Marquez-Curtis LA, Wysoczynski M, Ratajczak MZ (2006) Enhancing effect of platelet-derived microvesicles on the invasive potential of breast cancer cells. Transfusion 46(7):1199–1209
6. Labelle M, Begum S, Hynes RO (2011) Direct signaling between platelets and cancer cells induces an epithelial-mesenchymal-like transition and promotes metastasis. Cancer Cell 20(5):576–590
7. Cho MS, Bottsford-Miller J, Vasquez HG, Stone R, Zand B, Kroll MH, Sood AK, Afshar-Kharghan V (2012) Platelets increase the proliferation of ovarian cancer cells. Blood 120(24):4869–4872. doi:10.1182/blood-2012-06-438598
8. Chang YS, di Tomaso E, McDonald DM, Jones R, Jain RK, Munn LL (2000) Mosaic blood vessels in tumors: frequency of cancer cells in contact with flowing blood. Proc Natl Acad Sci USA 97(26):14608–14613
9. Gasic GJ (1984) Role of plasma, platelets, and endothelial cells in tumor metastasis. Cancer Metastasis Rev 3(2):99–114
10. Tanaka NG, Tohgo A, Ogawa H (1986) Platelet-aggregating activities of metastasizing tumor cells. V. In situ roles of platelets in hematogenous metastases. Invasion Metastasis 6(4):209–224
11. Honn KV, Tang DG, Crissman JD (1992) Platelets and cancer metastasis: a causal relationship? Cancer Metastasis Rev 11(3–4):325–351
12. Menter DG, Hatfield JS, Harkins C, Sloane BF, Taylor JD, Crissman JD, Honn KV (1987) Tumor cell-platelet interactions in vitro and their relationship to in vivo arrest of hematogenously circulating tumor cells. Clin Exp Metastasis 5(1):65–78
13. Nierodzik ML, Klepfish A, Karpatkin S (1995) Role of platelets, thrombin, integrin IIb-IIIa, fibronectin and von Willebrand factor on tumor adhesion in vitro and metastasis in vivo. Thromb Haemost 74(1):282–290
14. Coupland LA, Chong BH, Parish CR (2012) Platelets and P-selectin control tumor cell metastasis in an organ-specific manner and independently of NK cells. Cancer Res 72(18):4662–4671
15. Schumacher D, Strilic B, Sivaraj KK, Wettschureck N, Offermanns S (2013) Platelet-derived nucleotides promote tumor-cell transendothelial migration and metastasis via P2Y2 receptor. Cancer Cell 24(1):130–137. doi:10.1016/j.ccr.2013.05.008
16. Blair P, Flaumenhaft R (2009) Platelet alpha-granules: basic biology and clinical correlates. Blood Rev 23(4):177–189
17. Belloc C, Lu H, Soria C, Fridman R, Legrand Y, Menashi S (1995) The effect of platelets on invasiveness and protease production of human mammary tumor cells. Int J Cancer 60(3):413–417
18. Lindenmeyer F, Legrand Y, Menashi S (1997) Upregulation of MMP-9 expression in MDA-MB231 tumor cells by platelet granular membrane. FEBS Lett 418(1–2):19–22
19. Hawiger J (1989) Platelet secretory pathways: an overview. Methods Enzymol 169:191–195
20. Kim YJ, Borsig L, Varki NM, Varki A (1998) P-selectin deficiency attenuates tumor growth and metastasis. Proc Natl Acad Sci USA 95(16):9325–9330
21. Bretz N, Noske A, Keller S, Erbe-Hofmann N, Schlange T, Salnikov AV, Moldenhauer G, Kristiansen G, Altevogt P (2012) CD24 promotes tumor cell invasion by suppressing tissue factor pathway inhibitor-2 (TFPI-2) in a c-Src-dependent fashion. Clin Exp Metastasis 29(1):27–38. doi:10.1007/s10585-011-9426-4
22. Bastida E, Almirall L, Ordinas A (1987) Tumor-cell-induced platelet aggregation is a glycoprotein-dependent and lipoxygenase-associated process. Int J Cancer 39(6):760–763
23. Zhao F, Li L, Guan L, Yang H, Wu C, Liu Y (2014) Roles for GP IIb/IIIa and alphavbeta3 integrins in MDA-MB-231 cell invasion and shear flow-induced cancer cell mechanotransduction. Cancer Lett 344(1):62–73. doi:10.1016/j.canlet.2013.10.019
24. Borsig L, Wong R, Feramisco J, Nadeau DR, Varki NM, Varki A (2001) Heparin and cancer revisited: mechanistic connections involving platelets, P-selectin, carcinoma mucins, and tumor metastasis. Proc Natl Acad Sci USA 98(6):3352–3357