A Single Injection of Recombinant Adeno-Associated Virus into the Lumbar Cistern Delivers Transgene Expression Throughout the Whole Spinal Cord

Molecular Neurobiology

Volumn 53, Issue 5, 2016, Pages 3235-3248

  Guo, Yansu ^a,b   Wang, Dan ^b   Qiao, Tao ^b   Yang, Chunxing ^b   Su, Qin ^b   Gao, Guangping ^b   Xu, Zuoshang ^b  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

Author keywords

AAV; Amyotrophic lateral sclerosis; Gene therapy; Pain; rAAV; SMA

Indexed keywords

ADENOVIRUS VECTOR; MESSENGER RNA; MICRORNA; LIDOCAINE;

ADENO ASSOCIATED VIRUS; ANIMAL TISSUE; ARTICLE; BRAIN REGION; CONTROLLED STUDY; DRUG DISTRIBUTION; FRONTAL CORTEX; GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OLFACTORY BULB; SIGNAL TRANSDUCTION; SPINAL CORD; TRANSGENE; VIRAL GENE DELIVERY SYSTEM; ANIMAL; ANTIBODY SPECIFICITY; DEPENDOPARVOVIRUS; DRUG EFFECTS; GENETIC RECOMBINATION; GENETIC TRANSDUCTION; GENETICS; INFLAMMATION; INJECTION; LUMBAR VERTEBRA; METABOLISM; PATHOLOGY; PUNCTURE;

ANIMALS; DEPENDOVIRUS; INFLAMMATION; INJECTIONS; LIDOCAINE; LUMBAR VERTEBRAE; MICE; ORGAN SPECIFICITY; PUNCTURES; RECOMBINATION, GENETIC; TRANSDUCTION, GENETIC; TRANSGENES;

EID: 84930532618     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9223-1     Document Type: Article

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