The mosaic genome structure and phylogeny of Shiga toxin-producing Escherichia coli O104:H4 is driven by short-term adaptation

Clinical Microbiology and Infection

Volumn 21, Issue 5, 2015, Pages 468.e7-468.e18

  Zhou, K ^a   Ferdous, M ^a   de Boer, R F ^b   Kooistra Smid, A M D ^a,b   Grundmann, H ^a   Friedrich, A W ^a   Rossen, J W A ^a  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b Department of Medical Microbiology   (Netherlands)

Author keywords

Antibiotic resistance; Comparative genomics; Escherichia coli O104:H4; Genomic islands; Genomic structural variation; Next generation sequencing; Prophages; Shiga toxin producing Escherichia coli; Single nucleotide polymorphism; Stx2 encoding prophage

Indexed keywords

ARTICLE; GENE ISOLATION; GENE STRUCTURE; GENOME; GENOME ANALYSIS; MONOPHYLY; MOSAICISM; NONHUMAN; PHYLOGENY; POPULATION STRUCTURE; PRIORITY JOURNAL; SHIGA TOXIN PRODUCING ESCHERICHIA COLI; SINGLE NUCLEOTIDE POLYMORPHISM; ADAPTATION; ADOLESCENT; BACTERIAL GENOME; CHILD; CLASSIFICATION; EPIDEMIC; ESCHERICHIA COLI INFECTIONS; FEMALE; GENETIC SELECTION; GENETIC VARIATION; GENETICS; GENOTYPE; GERMANY; HUMAN; MALE; MICROBIOLOGY; MIDDLE AGED; MOLECULAR EVOLUTION; PRESCHOOL CHILD; YOUNG ADULT;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

ADAPTATION, BIOLOGICAL; ADOLESCENT; CHILD; CHILD, PRESCHOOL; DISEASE OUTBREAKS; ESCHERICHIA COLI INFECTIONS; EVOLUTION, MOLECULAR; FEMALE; GENETIC VARIATION; GENOME, BACTERIAL; GENOTYPE; GERMANY; HUMANS; MALE; MIDDLE AGED; SELECTION, GENETIC; SHIGA-TOXIGENIC ESCHERICHIA COLI; YOUNG ADULT;

EID: 84930531580     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1016/j.cmi.2014.12.009     Document Type: Article

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