The RAISE early treatment program for first-episode psychosis: Background, rationale, and study design

Journal of Clinical Psychiatry

Volumn 76, Issue 3, 2015, Pages 240-246

  Kane, John M ^a   Schooler, Nina R ^a   Marcy, Patrici ^a   Correll, Christoph U ^b   Brunette, Mary F ^c   Mueser, Kim T ^d   Rosenheck, Robert A ^e   Addington, Jea ^f   Estroff, Sue E ^g   Robinson, Jame ^h   Penn, David L ^i,k   Robinson, Delbert G ^a,j  

^a ZUCKER HILLSIDE HOSPITAL   (United States)

^b DONALD AND BARBARA ZUCKER SCHOOL OF MEDICINE AT HOFSTRA NORTHWELL   (United States)

^c FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH   (United States)

^d ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^e SUNY DOWNSTATE MEDICAL CENTER   (United States)

^f DARTMOUTH MEDICAL SCHOOL   (United States)

^g BOSTON UNIVERSITY   (United States)

^h YALE UNIVERSITY   (United States)

ⁱ UNIVERSITY OF CALGARY   (Canada)

^j UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^k NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; BRIEF PSYCHOTIC DISORDER; CONVALESCENCE; COST EFFECTIVENESS ANALYSIS; DSM-IV; EARLY INTERVENTION; EXPERIMENTAL THERAPY; FOLLOW UP; FUNCTIONAL STATUS; HUMAN; MAJOR CLINICAL STUDY; MULTIMODAL CHEMOTHERAPY; OUTCOME ASSESSMENT; PATIENT CARE; PATIENT SELECTION; PRIORITY JOURNAL; PSYCHOSIS; PSYCHOSOCIAL CARE; QUALITY OF LIFE; RANDOMIZATION; REIMBURSEMENT; REMISSION; SCHIZOAFFECTIVE PSYCHOSIS; SCHIZOPHRENIA; SCHIZOPHRENIFORM DISORDER; STUDY DESIGN; TREATMENT DURATION; METHODOLOGY; MULTICENTER STUDY (TOPIC); MULTIMODALITY CANCER THERAPY; PSYCHOTIC DISORDERS; RANDOMIZED CONTROLLED TRIAL; STANDARDS; YOUNG ADULT;

ADOLESCENT; ADULT; COMBINED MODALITY THERAPY; EARLY MEDICAL INTERVENTION; HUMANS; MULTICENTER STUDIES AS TOPIC; OUTCOME ASSESSMENT (HEALTH CARE); PRAGMATIC CLINICAL TRIALS AS TOPIC; PSYCHOTIC DISORDERS; RESEARCH DESIGN; SCHIZOPHRENIA; YOUNG ADULT;

EID: 84930517311     PISSN: 01606689     EISSN: 15552101     Source Type: Journal    
DOI: 10.4088/JCP.14m09289     Document Type: Article

References (34)

1. Robinson DG, Woerner MG, McMeniman M, et al. Symptomatic and functional recovery from a first episode of schizophrenia or schizoaffective disorder. Am J Psychiatry. 2004;161(3):473-479. doi:10.176/api.ajp.161.3.473
2. Jskelnen E, Juola P, Hirvonen N, et al. A systematic review and metaanalysis of recovery in schizophrenia. Schizophr Bull. 2013;39(6):1296-1306. doi:10.1093/schbul/sbs130
3. Robinson DG, Woerner MG, Napolitano B, et al. Randomized comparison of olanzapine versus risperidone for the treatment of first-episode schizophrenia: 4-month outcomes. Am J Psychiatry. 2006;163(12):2096-2102. doi:10.176/ajp.206.163.12.2096
4. Penn DL, Uzenoff SR, Perkins D, et al. A pilot investigation of the Graduated Recovery Intervention Program (GRIP) for first episode psychosis. Schizophr Res. 2011;125(2-3):247-256. doi:10.1016/j.schres.2010.08.06
5. Lenior ME, Dingemans PM, Schene AH, et al. The course of parental expressed emotion and psychotic episodes after family intervention in recentonset schizophrenia: a longitudinal study. Schizophr Res. 2002;57(2-3):183-190. doi:10.1016/S0920-964(01)0305-X
6. Killackey E, Jackson HJ, McGorry PD. Vocational intervention in first-episode psychosis: individual placement and support v treatment as usual. Br J Psychiatry. 2008;193(2):114-120. doi:10.192/bjp.bp.107.043109
7. McGorry PD, Edwards J, Mihalopoulos C, et al. EPPIC: an evolving system of early detection and optimal management. Schizophr Bull. 1996;22(2):305-326. doi:10.1093/schbul/2.2.305
8. Cullberg J, Levander S, Holmqvist R, et al. One-year outcome in first episode psychosis patients in the Swedish Parachute project. Acta Psychiatr Scand. 2002;106(4):276-285. doi:10.1034/j.160-047.202.02376.x
9. Malla AK, Norman RM, Manchanda R, et al. One year outcome in first episode psychosis: influence of DUP and other predictors. Schizophr Res. 2002;54(3):231-242. doi:10.1016/S0920-964(01)0254-7
10. Addington J, Leriger E, Addington D. Symptom outcome 1 year after admission to an early psychosis program. Can J Psychiatry. 2003;48(3):204-207.
11. Penn DL, Waldheter EJ, Perkins DO, et al. Psychosocial treatment for firstepisode psychosis: a research update. Am J Psychiatry. 2005;162(12):2220-2232. doi:10.176/api.ajp.162.12.20
12. Petersen L, Jeppesen P, Thorup A, et al. A randomised multicentre trial of integrated versus standard treatment for patients with a first episode of psychotic illness. BMJ. 2005a;331(7517):602-609. doi:10.136/bmj.38565.4150.E01
13. Petersen L, Nordentoft M, Jeppesen P, et al. Improving 1-year outcome in first-episode psychosis: OPUS trial. Br J Psychiatry suppl. 2005b;187(suppl):s98-s103. doi:10.192/bjp.187.48.s98
14. Bertelsen M, Jeppesen P, Petersen L, et al. Five-year follow-up of a randomized multicenter trial of intensive early intervention vs standard treatment for patients with a first episode of psychotic illness: the OPUS trial. Arch Gen Psychiatry. 2008;65(7):762-771. doi:10.101/archpsyc.65.7.762
15. Craig TK, Garety P, Power P, et al. The Lambeth Early Onset (LEO) Team: randomised controlled trial of the effectiveness of specialised care for early psychosis. BMJ. 2004;329(7474):1067. doi:10.136/bmj.38246.594873.7C
16. Sigrarson V, Gre RW, Morken G. Integrated treatment vs treatment-Asusual for recent onset schizophrenia; 12 year follow-up on a randomized controlled trial. BMC Psychiatry. 2013;13(1):200. doi:10.186/1471-24X-13-20
17. Birchwood M, Todd P, Jackson C. Early intervention in psychosis: the critical period hypothesis. Br J Psychiatry Suppl. 1998;172(33):53-59.
18. Bertolote J, McGorry P. Early intervention and recovery for young people with early psychosis: consensus statement. Br J Psychiatry suppl. 2005;187(suppl 48):s116-s119. doi:10.192/bjp.187.48.s16
19. First MB, Spitzer RL, Gibbon M, et al. Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), Clinician Version, Administration Booklet. Washington, DC: American Psychiatric Publishing; 2012.
20. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull. 1987;13(2):261-276. doi:10.1093/schbul/13.2.261
21. Guy W. Clinical Global Impressions. In: ECDEU Assessment Manual for Psychopharmacology, Revised (DHEW Publ No ADM 76-338). Rockville, MD: National Institute of Mental Health; 1976;218-222.
22. Addington D, Addington J, Maticka-Tyndale E. Assessing depression in schizophrenia: the Calgary Depression Scale. Br J Psychiatry suppl. 1993;163(22):39-44.
23. Heinrichs DW, Hanlon TE, Carpenter WT Jr. The Quality of Life Scale: an instrument for rating the schizophrenic deficit syndrome. Schizophr Bull. 1984;10(3):388-398. doi:10.1093/schbul/10.3.38
24. Rosenheck RA, Kasprow W, Frisman LK, et al. Cost-effectiveness of supported housing for homeless persons with mental illness. Arch Gen Psychiatry. 2003;60(9):940-951. doi:10.101/archpsyc.60.9.940
25. Leon AC, Demirtas H, Hedeker D. Bias reduction with an adjustment for participants intent to dropout of a randomized controlled clinical trial. Clin Trials. 2007;4(5):540-547. doi:10.17/174074507083871
26. Keefe RSE, Harvey PD, Goldberg TE, et al. Norms and standardization of the Brief Assessment of Cognition in Schizophrenia (BACS). Schizophr Res. 2008;102(1-3):108-115. doi:10.1016/j.schres.208.03.024
27. Haddad L, Meyer-Lindenberg A. Social environmental risk factors and mental disorders: insights into underlying neural mechanisms drawing on the example of urbanicity [article in German]. Nervenarzt. 2012;83(11):1403-1409. doi:10.107/s015-012-364-9
28. Shen J, Kobak KA, Zhao Y, et al. Use of remote centralized raters via live 2-way video in a multicenter clinical trial for schizophrenia. J Clin Psychopharmacol. 2008;28(6):691-693. doi:10.1097/JCP.0b013e31818c9ba3
29. Zarate Jr. C.A., Weinstock L, Cukor P, et al. Applicability of telemedicine for assessing patients with schizophrenia: acceptance and reliability. J Clin Psychiatry. 1997;58(1):22-25. doi:10.408/JCP.v58n0104
30. Rowe M, Rosenheck R, Stern E, et al. Video conferencing technology in research on schizophrenia: a qualitative study of site research staff. Psychiatry. 2014;77(1):98-102.
31. Rosenheck RA, Leslie DL, Sindelar J, et al; CATIE Study Investigators. Costeffectiveness of second-generation antipsychotics and perphenazine in a randomized trial of treatment for chronic schizophrenia. Am J Psychiatry. 2006;163(12):2080-2089. doi:10.176/ajp.206.163.12.2080
32. Ten Have TR, Localio AR. Empirical Bayes estimation of random effects parameters in mixed effects logistic regression models. Biometrics. 1999;55(4):1022-1029. doi:10.1/j.06-341X.19.0102.x
33. Goldstein H. Multilevel Statistical Models. 4th ed. London, UK: Wiley; 2011.
34. Hedeker D, Gibbons RD. Longitudinal Data Analysis. Hoboken, New Jersey: Wiley; 2006.