Development of a tool for defining and identifying the dying patient in hospital: Criteria for Screening and Triaging to Appropriate aLternative care (CriSTAL)

BMJ Supportive and Palliative Care

Volumn 5, Issue 1, 2015, Pages 78-90

  Cardona Morrell, Magnolia ^a   Hillman, Ken ^a  

^a UNIVERSITY OF NEW SOUTH WALES   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

AGED; EMERGENCY HEALTH SERVICE; HEALTH STATUS INDICATOR; HOSPITAL PATIENT; HUMAN; PROCEDURES; PROGNOSIS; TERMINALLY ILL PATIENT; UNCERTAINTY;

AGED; HEALTH STATUS INDICATORS; HUMANS; INPATIENTS; PROGNOSIS; TERMINALLY ILL; TRIAGE; UNCERTAINTY;

EID: 84930512028     PISSN: 2045435X     EISSN: 20454368     Source Type: Journal    
DOI: 10.1136/bmjspcare-2014-000770     Document Type: Review

References (112)

1. Tsim S, Davidson S. End-of-life care in a general respiratory ward in the United Kingdom. Am J Hosp Palliat Med 2014;31:172-4.
2. The Scottish Government. Living and dying well: building on progress. Secondary living and dying well: building on progress 2011. http://www.scotland.gov.uk/Resource/Doc/340076/0112559.pdf.
3. Hillman K. Dying safely. Int J Qual Health Care 2010;22:339-40.
4. Higginson IJ, Sen-Gupta GJ. Place of care in advanced cancer: a qualitative systematic literature review of patient preferences. J Palliat Med 2000;3:287-300.
5. Beccaro M, Costantini M, Giorgi Rossi P, et al. Actual and preferred place of death of cancer patients. Results from the Italian survey of the dying of cancer (ISDOC). J Epidemiol Community Health 2006;60:412-16.
6. Brazil K, Howell D, Bedard M, et al. Preferences for place of care and place of death among informal caregivers of the terminally ill. Palliat Med 2005;19:492-9.
7. Cohen J, Bilsen J, Addington-Hall J, et al. Population-based study of dying in hospital in six European countries. Palliat Med 2008;22:702-10.
8. Wilson DM, Truman CD, Thomas R, et al. The rapidly changing location of death in Canada, 1994-2004. Soc Sci Med 2009;68:1752-8.
9. Lowthian JA, Jolley DJ, Curtis AJ, et al. The challenges of population ageing: accelerating demand for emergency ambulance services by older patients, 1995-2015. Med J Aust 2011;194:574-8.
10. Rosenwax LK, McNamara BA, Kevin Murray K, et al. Hospital and emergency department use in the last year of life: a baseline for future modifications to end-of-life care. Med J Aust 2011;194:570-73.
11. Hillman K. The changing role of acute-care hospitals. Med J Aust 1999;170:325-28.
12. Earle CC, Landrum MB, Souza JM, et al. Aggressiveness of cancer care near the end of life: is it a quality-of-care issue? J Clin Oncol 2008;26:3860-6.
13. Earle CC, Park ER, Lai B, et al. Identifying potential indicators of the quality of end-of-life cancer care from administrative data. J Clin Oncol 2003;21:1133-8.
14. Senthuran S, Bandeshe H, Ranganathan D, et al. Outcomes for dialysis patients with end-stage renal failure admitted to an intensive care unit or high dependency unit. Med J Aust 2008;188:292-5.
15. Stolman CJ, Gregory JJ, Dunn D, et al. Evaluation of the do not resuscitate orders at a community hospital. Arch Intern Med 1989;149:1851-6.
16. Weissman D. Policy Forum. Policy Proposal: Do Not Resuscitate Orders: A Call for Reform. Virtual Mentor [Internet]. 2003 [cited 2014 August]; 5(1). Available from: http://virtualmentor.ama-assn.org/2003/01/pfor2-0301.html.
17. Holloway RG, Benesch CG, Burgin WS, et al. Prognosis and decision making in severe stroke. JAMA 2005;294: 725-33.
18. van Walraven C, Austin PC, Jennings A, et al. A modification of the Elixhauser comorbidity measures into a point system for hospital death using administrative data. Med Care 2009;47:626-33.
19. Phillips G. Do not resuscitate orders: a reappraisal. HEC Forum 1990;2:101-4.
20. Wright AA, Zhang B, Ray A, et al. Associations between end-of-life discussions, patient mental health, medical care near death, and caregiver bereavement adjustment. JAMA 2008;300:1665-73.
21. National Health Service. End of Life Care Strategy. Promoting high quality care for all adults at the end of life. July. Secondary End of Life Care Strategy. Promoting high quality care for all adults at the end of life. July 2008. http://webarchive.nationalarchives.gov.uk/20130107105354/http://www.dh.gov.uk/prod_consum_dh/groups/dh_digitalassets/dh/en/documents/digitalasset/dh_086345.pdf.
22. van Weel C, Michels J. Dying, not old age, to blame for costs of health care. Lancet 1997;350:1159-60.
23. Curtis JR, Engelberg RA, Bensink ME, et al. End-of-life care in the intensive care unit. Can we simultaneously increase quality and reduce costs? Am J Respir Crit Care Med 2012;186:587-92.
24. Oshima Lee E, Emanuel EJ. Shared decision making to improve care and reduce costs. N Engl J Med 2013;368: 6-8.
25. Downar J, Rodin D, Barua R, et al. Rapid response teams, do not resuscitate orders, and potential opportunities to improve end-of-life care: a multicentre retrospective study. J Crit Care 2013;28:498-503.
26. Gleeson K. The do-not-resuscitate order: still too little too late. Arch Intern Med 1990;150:1057-60.
27. Mead GE, Turnbull CJ. Cardiopulmonary resuscitation in the elderly: patients' and relatives' views. J Med Ethics 1995;21:39-44.
28. Heyland DK, Dodek P, Rocker G, et al. What matters most in end-of-life care: perceptions of seriously ill patients and their family members. CMAJ 2006;174:627-33.
29. Kompanje EJ, Piers RD, Benoit DD. Causes and consequences of disproportionate care in intensive care medicine. Curr Opin Crit Care 2013;19:630-5.
30. Hillman K, Chen J, Cretikos M, et al. Introduction of the medical emergency team (MET) system: a cluster-randomised controlled trial. Lancet 2005;24:2091-7.
31. Mitchell IA, McKay H, Van Leuvan C, et al. A prospective controlled trial of the effect of a multi-faceted intervention on early recognition and intervention in deteriorating hospital patients. Resuscitation 2010;81:658-66.
32. Goldhill DR, McNarry AF. Physiological abnormalities in early warning scores are related to mortality in adult inpatients†. Br J Anaesth 2004;92:882-84.
33. Jones DA, Bagshaw SM, Barrett J, et al. The role of the medical emergency team in end-of-life care: a multicenter, prospective, observational study. Crit Care Med 2012;40:98-103.
34. Jones D, Moran J, Winters B, et al. The rapid response system and end-of-life care. Curr Opin Crit Care 2013;19:616-23.
35. Jones DA, McIntyre T, Baldwin I, et al. The medical emergency team and end-of-life care: a pilot study. Crit Care Resusc 2007;9:151-56.
36. Stacey D, Legare F, Col NF, et al. Decision aids for people facing health treatment or screening decisions. Cochrane Database Syst Rev 2014;1: CD001431.
37. van Walraven C, Forster AJ, Stiell IG. Derivation of a clinical decision rule for the discontinuation of in-hospital cardiac arrest resuscitations. Ann Intern Med 1999;159:129-34.
38. Kennedy C, Brooks-Young P, Brunton Gray C, et al. Diagnosing dying: an integrative literature review. BMJ Support Palliat Care 2014;4:263-70.
39. Curtis JR, Engelberg RA, Nielsen EL, et al. Patient-physician communication about end-of-life care for patients with severe COPD. Eur Respir J 2004;24:200-5.
40. Gomes B, Higginson IJ. Home or hospital? Choices at the end of life. J Royal Soc Med 2004;97:413-14.
41. Paterson BC, Duncan R, Conway R, et al. Introduction of the Liverpool Care Pathway for end of life care to emergency medicine. Emerg Med J 2009;26:777-9.
42. Viganò A, Dorgan M, Buckingham J, et al. Survival prediction in terminal cancer patients: a systematic review of the medical literature. Palliat Med 2000;14:363-74.
43. Escobar GJ, Greene JD, Scheirer P, et al. Risk-adjusting hospital inpatient mortality using automated inpatient, outpatient, and laboratory databases. Med Care 2008;46:232-9.
44. Rothman SI, Rothman MJ, Solinger AB. Placing clinical variables on a common linear scale of empirically based risk as a step towards construction of a general patient acuity score from the electronic health record: a modelling study. BMJ Open 2013;13:e002367.
45. Wang CY, Calfee CS, Paul DW, et al. One-year mortality and predictors of death among hospital survivors of acute respiratory distress syndrome. Intensive Care Med 2014;40:388-96.
46. Kellett J, Deane B. The Simple Clinical Score predicts mortality for 30 days after admission to an acute medical unit. QJM 2006;99:771-81.
47. Sharif N, Irfan M, Hussain J, et al. Factors Associated within 28 Days In-Hospital Mortality of Patients with Acute Respiratory Distress Syndrome BioMed Research International 2013; Article ID 564547:5 pages doi: http://dx.doi.org/10. 1155/2013/564547 [ published Online First: Epub Date].
48. President's Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research. Defining death. medical, legal and ethical issues in the determination of death. 1981 https://bioethicsarchive.georgetown.edu/pcbe/reports/past_commissions/defining_death.pdf (accessed Mar 2013).
49. Blackhall LJ. Must we always use CPR? New England J Med 1987;317:1281-5.
50. Tomlinson T, Brody H. Futility and the ethics of resuscitation. JAMA 1990;264:1276-80.
51. Australian Government Department of Health and Ageing. Guidelines for a Palliative Approach in Residential Aged Care. Secondary Guidelines for a Palliative Approach in Residential Aged Care 2006. http://www.nhmrc.gov.au/_files_nhmrc/publications/attachments/pc29.pdf.
52. Schmidt RJ, Moss AH. Dying on dialysis: the case for a dignified withdrawal. Clin J Am Soc Nephrol 2014;9:174-80.
53. Clark A, Fallowfield LJ. Quality of life measures in patients with malignant disease. J Royal Soc Med 1986;79:165-69.
54. Addington-Hall MacDonald, LD Anderson HR. Can the Spitzer quality of life index help to reduce prognostic uncertainty in terminal care? Br J Cancer 1990;62:695-99.
55. Péus D, Newcomb N, Hofer S. Appraisal of the Karnofsky performance status and proposal of a simple algorithmic system for its evaluation. BMC Med Inform Decis Mak 2013;13:72.
56. Rothman MJ, Solinger AB, Rothman SI, et al. Clinical implications and validity of nursing assessments: a longitudinal measure of patient condition from analysis of the Electronic Medical Record. BMJ Open 2012;2: pii: e000646.
57. Fromme EK, Smith MD, Bascom PB, et al. Incorporating routine survival prediction in a US hospital-based palliative care service. J Palliat Med 2010;13:1439-44.
58. Rockwood K, Song X, MacKnight C, et al. A global clinical measure of fitness and frailty in elderly people. CMAJ 2005;173:489-5.
59. Weiche RE, Mundy BJ, Skokan L, et al. Patient-centered research. Identifying patients nearing the end of life from congestive heart failure or chronic obstructive pulmonary disease. J Gen Intern Med 2000;15(Suppl 2):9-10.
60. Mossey JM, Shapiro E. Self-rated health: a predictor of mortality among the elderly. Am J Public Health 1982;72:800-8.
61. Jylhä M. What is self-rated health and why does it predict mortality? Towards a unified conceptual model. Soc Sci Med 2009;69:307-16.
62. Heistaro S, Jousilahti P, Lahelma E, et al. Self rated health and mortality: a long term prospective study in eastern Finland. J Epidemiol Community Health 2001;55:227-32.
63. Saliba D, Elliott M, Rubenstein LZ, et al. The vulnerable elders survey: a tool for identifying vulnerable older people in the community. J Am Geriatr Soc 2001;49:1691-9.
64. Knaus WA, Draper EA, Wagner DP, et al. APACHE II: a severity of disease classification system. Crit Care Med 1985;13:818-29.
65. McMahon LF Jr, Hayward RA, Bernard AM, et al. APACHE-L: a new severity of illness adjuster for inpatient medical care. Med Care 1992;30:445-2.
66. Del Bufalo C, Morelli A, Bassein L, et al. Severity scores in respiratory intensive care: APACHE II predicted mortality better than SAPS II. Respir Care 1995;40:1042-7.
67. Zimmerman JE, Kramer AA, McNair DS, et al. Acute Physiology and Chronic Health Evaluation (APACHE) IV: hospital mortality assessment for today's critically ill patients. Crit Care Med 2006;34:1297-310.
68. Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40:373-83.
69. Pompei P, Charlson ME, Gordon Douglas R Jr. Clinical assessments as predictors of one year survival after hospitalization: Implications for prognostic stratification. J Clin Epidemiol 1988;41:275-84.
70. Le Gall J, Lemeshow S, Saulnier F. A new simplified acute physiology score (saps ii) based on a European/north American multicenter study. JAMA 1993;270:2957-63.
71. Anderson F, Downing GM, Hill J, et al. Palliative performance scale (PPS): a new tool. J Palliat Care 1996;12:5-11.
72. Virik K, Glare P. Validation of the Palliative Performance Scale for Inpatients admitted to a palliative care unit in Sydney, Australia. J Pain Symptom Manage 2002;23:455-7.
73. Elixhauser A, Steiner C, Harris DR, et al. Comorbidity measures for use with administrative data. Med Care 1998;36:8-27.
74. Austin SR, Wong YN, Uzzo RG, et al. Why summary comorbidity measures such as the Charlson comorbidity index and Elixhauser score work. Med Care 2013. Published Online First (May 23) doi:10.1097/MLR.0b013e318297429c.
75. Subbe CP, Kruger M, Rutherford P, et al. Validation of a modified early warning score in medical admissions. QJM 2001;94:521-26.
76. Glare PA, Eychmueller S, McMahon P. Diagnostic accuracy of the palliative prognostic score in hospitalized patients with advanced cancer. J Clin Oncol 2004;22:4823-8.
77. Maltoni M, Scarpi E, Pittureri C, et al. Prospective comparison of prognostic scores in palliative care cancer populations. Oncologist 2012;17:446-54.
78. Paterson R, MacLeod DC, Thetford D, et al. Prediction of in-hospital mortality and length of stay using an early warning scoring system: clinical audit. Clin Med 2006;6:281-84.
79. Kuo S-H, Tsai C-F, Li C-R, et al. Rapid emergency medicine score as a main predictor of mortality in Vibrio vulnificus-related patients. Am J Emerg Med 2013;31:1037-41.
80. Kellett J, Rasool S, McLoughlin B. Prediction of mortality 1 year after hospital admission. QJM 2012;105:847-53.
81. Groarke JD, Gallagher J, Stack J, et al. Use of an admission early warning score to predict patient morbidity and mortality and treatment success. Emerg Med J 2008;25:803-6.
82. Stone CA, Tiernan E, Dooley BA. Prospective validation of the palliative prognostic index in patients with cancer. J Pain Symptom Manage 2008;35:617-22.
83. Glare P, Sinclair C, Downing M, et al. Predicting survival in patients with advanced disease. Eur J Cancer 2008;44:1146-56.
84. Prytherch DR, Smith GB, Schmidt PE, et al. ViEWS-Towards a national early warning score for detecting adult inpatient deterioration. Resuscitation 2010;81:932-7.
85. Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci 2001;56:M146-57.
86. Hucker TR, Mitchell GP, Blake LD, et al. Identifying the sick: can biochemical measurements be used to aid decision making on presentation to the accident and emergency department. Br J Anaesth 2005;94:735-41.
87. Alloway L, Minton O. The accuracy of the clinical prediction of survival: a comparison of doctors' and nurses' estimations and the failure to validate the Palliative Prognostic Score [abstract for the 5th palliative care congress, UK]. Palliat Med 2004;18:155.
88. Lübke T, Mönig SP, Schneider PM, et al. Does Charlson-comorbidity index correlate with short-term outcome in patients with hastric cancer? [Article in German]. Zentralbl Chir 2003;128:970-6.
89. Le Maguet P, Roquilly A, Lasocki S, et al. Prevalence and impact of frailty on mortality in elderly ICU patients: a prospective, multicenter, observational study. Intensive Care Med 2014:1-9.
90. Vincent JL, Moreno R. Clinical review: scoring systems in the critically ill. Crit Care 2010;14:207.
91. Hands C, Reid E, Meredith P, et al. Patterns in the recording of vital signs and early warning scores: compliance with a clinical escalation protocol. BMJ Qual Saf 2013;22:719-26.
92. Moon A, Cosgrove JF, Lea D, et al. An eight year audit before and after the introduction of modified early warning score (MEWS) charts, of patients admitted to a tertiary referral intensive care unit after CPR. Resuscitation 2011;82:150-54.
93. Parham G. Recognition and response to the clinically deteriorating patient. MJA 2012;3:18-22.
94. Morgan RJM, Wright MM. In defence of early warning scores. Br J Anaesth 2007;99:747-48.
95. Kramer AA, Higgins TL, Zimmerman JE. Intensive care unit readmissions in US hospitals: patient characteristics, risk factors, and outcomes. Crit Care Med 2012;40:3-10.
96. Levine SK, Sachs GA, Jin L, et al. A prognostic model for 1-year mortality in older adults after hospital discharge. Am J Med 2007;120:455-60.
97. Copeland GP, Jones D, Walters M. POSSUM: a scoring system for surgical audit. Br J Surg 1991;78:355-60.
98. DeVita MA, Smith GB, Adam SK, et al. "Identifying the hospitalised patient in crisis"-a consensus conference on the afferent limb of Rapid Response Systems. Resuscitation 2010;81:375-82. http://dx.doi.org/10.1016/j.resuscitation. 2009.12.008.
99. Cretikos M, Parr M, Hillman K, et al. Guidelines for the uniform reporting of data for Medical Emergency Teams. Resuscitation 2006;68:11-25.
100. Cerda J. Oliguria: an earlier and accurate biomarker of acute kidney injury [quest]. Kidney Int 2011;80:699-701.
101. Krumholz HM, Merrill AR, Schone EM, et al. Patterns of hospital performance in acute myocardial infarction and heart failure 30-day mortality and readmission. Circ Cardiovasc Qual Outcomes 2009;2:407-13.
102. Knaus WA, Harrell FE Jr, Lynn J, et al. The SUPPORT prognostic model. Objective estimates of survival for seriously ill hospitalized adults. Study to understand prognoses and preferences for outcomes and risks of treatments. Ann Intern Med 1995;122:191-203.
103. Peralta CA, Shlipak MG, Judd S, et al. Detection of chronic kidney disease with creatinine, cystatin c, and urine albumin-to-creatinine ratio and association with progression to end-stage renal disease and mortality. JAMA 2011;305:1545-52.
104. Kaukonen K, Bailey M, Suzuki S, et al. Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000-2012. JAMA 2014;311:1308-16.
105. Lynn J, Teno JM, Harrell FE Jr. Accurate prognostications of death. Opportunities and challenges for clinicians. West J Med 1995;163:250-7.
106. Fawcett T. An introduction to ROC analysis. Pattern Recognit Lett 2006;27:861-74.
107. Brabrand M, Folkestad L, Clausen NG, et al. Risk scoring systems for adults admitted to the emergency department: a systematic review. Scand J Trauma Resusc Emerg Med 2010;18:1-8.
108. Simon ST, Martens M, Sachse M, et al. Liverpool Care Pathway" (LCP) in Deutschland. Care of the dying in hospital: initial experience with the Liverpool Care Pathway (LCP) in Germany. Dtsch Med Wochenschr 2009;134:1399-404.
109. Waldrop DP, Kirkendall AM. Comfort measures: a qualitative study of nursing home-based end-of-life care. J Palliat Med 2009;12:719-24.
110. Ryder-Lewis M. Going home from ICU to die: a celebration of life*. Nurs Crit Care 2005;10:116-21.
111. Horey DE, Street AF, Sands AF. Acceptability and feasibility of end-of-life care pathways in Australian residential aged care facilities. Med J Aust 2012;197:106-9.
112. Cherniack E. Increasing use of DNR orders in the elderly worldwide: whose choice is it? J Med Ethics 2002;28:303-07.