Effect of standardized decoction of Nigella sativa seed, Hemidesmus indicus root and smilax glabra rhizome on the expression of p53 and p21 genes in human hepatoma cells (HepG2) and mouse liver with chemically-induced hepatocarcinogenesis

Tropical Journal of Pharmaceutical Research

Volumn 11, Issue 1, 2012, Pages 51-61

  Samarakoon, Sameera R ^a   Thabrew, Ira ^a   Galhena, Prasanna B ^b   Tennekoon, Kamani H ^a  

^a UNIVERSITY OF COLOMBO   (Sri Lanka)

^b UNIVERSITY OF KELANIYA   (Sri Lanka)

Author keywords

Diethylnitrosamine; Hemidesmus indicus; HepG2 cells; Nigella sativa; p21; p53; Smilax glabra

Indexed keywords

ANTINEOPLASTIC AGENT; DIETHYLNITROSAMINE; HEMIDESMUS INDICUS EXTRACT; MESSENGER RNA; NIGELLA SATIVA EXTRACT; PLANT EXTRACT; PROTEIN P21; PROTEIN P53; SMILAX GLABRA EXTRACT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CHEMICAL CARCINOGENESIS; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LIVER CELL CARCINOMA; MALE; MEDICINAL PLANT; MOUSE; NONHUMAN; P21 GENE; PLANT ROOT; PLANT SEED; PROTEIN EXPRESSION; RHIZOME; SMILAX GLABRA; TUMOR SUPPRESSOR GENE;

EID: 84930481800     PISSN: 15965996     EISSN: 15969827     Source Type: Journal    
DOI: 10.4314/tjpr.v11i1.7     Document Type: Article

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