Effects of the synthetic coprisin analog peptide, CopA3 in pathogenic microorganisms and mammalian cancer cells

Journal of Microbiology and Biotechnology

Volumn 22, Issue 1, 2012, Pages 156-158

  Kim, In Woo ^a   Kim, Soon Ja ^a   Kwon, Yong Nam ^a   Yun, Eun Young ^a   Ahn, Mi Young ^a   Kang, Dong Chul ^b   Hwang, Jae Sam ^a  

^a National Institute of Animal Science   (South Korea)

^b Hallym University   (South Korea)

Author keywords

Antimicrobial activity; Antimicrobial peptide; Coprisin analog peptide CopA3; Defensin

Indexed keywords

COPRISIN; MELITTIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; GROWTH INHIBITION; HUMAN; HUMAN CELL; IC 50; LIVER CELL CARCINOMA; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PANCREAS CANCER;

BACTERIA (MICROORGANISMS); COLEOPTERA; COPRIS; FUNGI; MAMMALIA;

EID: 84930480990     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.1109.09014     Document Type: Article

References (21)

1. Baker, M. A., W. L. Maloy, M. Zasloff, and L. S. Jacob. 1993. Anticancer efficacy of Magainin2 and analogue peptides. Cancer Res. 53: 3052-3057.
2. Barbault, F., C. Landon, M. Guenneugues, J. P. Meyer, V. Schott, J. L. Dimarcq, and F. Vovelle. 2003. Solution structure of Alo-3: A new knottin-type antifungal peptide from the insect Acrocinus longimanus. Biochemistry 42: 14434-14442.
3. Bulet, P., S. Cociancich, M. Reuland, F. Sauber, R. Bischoff, G. Hegy, et al. 1992. A novel insect defensin mediates the inducible antibacterial activity in larvae of the dragonfly Aeschna cyanea (Paleoptera, Odonata). Eur. J. Biochem. 209: 977-984.
4. Bulet, P., C. Hetru, J. L. Dimarcq, and D. Hoffmann. 1999. Antimicrobial peptides in insects; structure and function. Dev. Comp. Immunol. 23: 329-344.
5. Bulet, P. and R. Stocklin. 2005. Insect antimicrobial peptides: Structures, properties and gene regulation. Protein Pept. Lett. 12: 3-11.
6. Cociancich, S., A. Ghazi, C. Hetru, J. A. Hoffmann, and L. Letellier. 1993. Insect defensin, an inducible antibacterial peptide, forms voltage-dependent channels in Micrococcus luteus. J. Biol. Chem. 268: 19239-19245.
7. Dempsey, C. E. 1990. The actions of melittin on membranes. Biochim. Biophys. Acta 1031: 143-161.
8. Hancock, R. E. and D. S. Chapple. 1999. Peptide antibiotics. Antimicrob. Agents Chemother. 43: 1317-1323.
9. Hancock, R. E. and M. G. Scott. 2000. The role of antimicrobial peptides in animal defenses. Proc. Natl. Acad. Sci. USA 97: 8856-8861.
10. Hwang, J. S., J. Lee, Y. J. Kim, H. S. Bang, E. Y. Yun, S. R. Kim, et al. 2009. Isolation and characterization of a defensinlike peptide (coprisin) from the dung beetle, Copris tripartitus. Int. J. Pept. 2009.
11. Iwasaki, T., J. Ishibashi, H. Tanaka, M. Sato, A. Asaoka, D. Taylor, et al. 2009. Selective cancer cell cytotoxicity of enantiomeric 9-mer peptides derived from beetle defensins depends on negatively charged phosphatidylserine on the cell surface. Peptides 30: 660-668.
12. Lehmann, J., M. Retz, S. S. Sidhu, H. Suttmann, M. Sell, F. Paulsen, et al. 2006. Antitumor activity of the antimicrobial peptide magainin II against bladder cancer cell lines. Eur. Urol. 50: 141-147.
13. Moore, A. J., D. A. Devine, and M. C. Bibby. 1994. Preliminary experimental anticancer activity cecropins. Pept. Res. 7: 265-269.
14. Papo, N., A. Braunstein, Z. Eshhar, and Y. Shai. 2004. Suppression of human prostate tumor growth in mice by a cytolytic D-, L-amino acid peptide, membrane lysis, increased necrosis, and inhibition of prostate-specific antigen secretion. Cancer Res. 64: 5779-5786.
15. Papo, N. and Y. Shai. 2003. New lytic peptides based on the D, L-amphipathic helix motif preferentially kill tumor cells compared to normal cells. Biochemistry 42: 9346-9354.
16. Papo, N. and Y. Shai. 2005. Host defense peptides as new weapons in cancer treatment. Cell Mol. Life Sci. 62: 784-790.
17. Schuhmann, B., V. Seitz, A. Vilcinskas, and L. Podsiadlowski. 2003. Cloning and expression of gallerimycin, an antifungal peptide expressed in immune response of greater wax moth larvae, Galleria mellonella. Arch. Insect Biochem. Physiol. 53: 125-133.
18. Soballe, P. W., W. L. Maloy, M. L. Myrga, L. S. Jacob, and M. Herlyn. 1995. Experimental local therapy of human melanoma with lytic magainin peptides. Int. J. Cancer 60: 280-284.
19. Thevissen, K., K. K. Ferket, I. E. Francois, and B. P. Cammue. 2003. Interactions of antifungal plant defensins with fungal membrane components. Peptides 24: 1705-1712.
20. Tosteson, M. T., S. J. Holmes, M. Razin, and D. C. Tosteson. 1985. Melittin lysis of red cells. J. Membr. Biol. 87: 35-44.
21. Xiao, Y. C., Y. D. Huang, P. L. Xu, Z. Q. Zhou, and X. K. Li. 2006. Pro-apoptotic effect of cecropin AD on nasopharyngeal carcinoma cells. Chin. Med. J. (Engl.) 119: 1042-1046.