Adipose-Derived Stem Cells Ameliorate Allergic Airway Inflammation by Inducing Regulatory T Cells in a Mouse Model of Asthma

Mediators of Inflammation

Volumn 2014, Issue , 2015, Pages

  Cho, Kyu Sup ^a   Park, Mi Kyung ^b   Kang, Shin Ae ^b   Park, Hee Young ^a   Hong, Sung Lyong ^a   Park, Hye Kyung ^a   Yu, Hak Sun ^b   Roh, Hwan Jung ^c  

^a Pusan National University Hospital   (South Korea)

^b Pusan National University School of Medicine   (South Korea)

^c Pusan National University Yangsan Hospital   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; TRANSFORMING GROWTH FACTOR BETA; PROSTAGLANDIN E2;

ADIPOSE DERIVED STEM CELL; ALLERGIC AIRWAY INFLAMMATION; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; CYTOKINE RELEASE; EOSINOPHIL; FEMALE; HISTOLOGY; IMMUNOCOMPETENT CELL; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOMODULATION; LUNG LAVAGE; MOUSE; MUCUS SECRETION; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REGULATORY T LYMPHOCYTE; RESPIRATORY TRACT ALLERGY; STEM CELL TRANSPLANTATION; UPREGULATION; ADIPOSE TISSUE; ANIMAL; C57BL MOUSE; CELL CULTURE; CYTOLOGY; IMMUNOLOGY; METABOLISM; TH2 CELL;

ADIPOSE TISSUE; ANIMALS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; CELLS, CULTURED; DINOPROSTONE; FEMALE; INTERLEUKIN-10; INTERLEUKIN-13; INTERLEUKIN-4; INTERLEUKIN-5; MICE; MICE, INBRED C57BL; STEM CELL TRANSPLANTATION; T-LYMPHOCYTES, REGULATORY; TH2 CELLS;

EID: 84930411457     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2014/436476     Document Type: Article

References (36)

1. J. Bousquet, N. Khaltaev, A. A. Cruz et al., "Allergic Rhinitis and its Impact onAsthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA2LEN and AllerGen)", Allergy, vol. 63, no. 86, pp. 8-160, 2008.
2. L. Cohn, J. A. Elias, and G. L. Chupp, "Asthma: mechanisms of disease persistence and progression", Annual Review of Immunology, vol. 22, pp. 789-815, 2004.
3. M. S. Wilson, M. D. Taylor, A. Balic, C. A. M. Finney, J. R. Lamb, and R. M. Maizels, "Suppression of allergic airway inflammation by helminth-induced regulatory T cells", Journal of Experimental Medicine, vol. 202, no. 9, pp. 1199-1212, 2005.
4. K. S. Cho, H. Y. Park, H. J. Roh, D. T. Bravo, P. H. Hwang, and J. V. Nayak, "Human ethmoid sinus mucosa: a promising novel tissue source of mesenchymal progenitor cells", Stem Cell Research & Therapy, vol. 5, article 15, 2014.
5. R. S. Tuan, G. Boland, and R. Tuli, "Adult mesenchymal stem cells and cell-based tissue engineering", Arthritis Research and Therapy, vol. 5, no. 1, pp. 32-45, 2003.
6. H. Klingemann, D. Matzilevich, and J. Marchand, "Mesenchymal stem cells-sources and clinical applications", Transfusion Medicine and Hemotherapy, vol. 35, no. 4, pp. 272-277, 2008.
7. A. Uccelli, L. Moretta, and V. Pistoia, "Immunoregulatory function of mesenchymal stem cells", European Journal of Immunology, vol. 36, no. 10, pp. 2566-2573, 2006.
8. Z. Selmani, A. Naji, I. Zidi et al., "Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer functionand to induce CD4+ CD25highFOXP3+ regulatory T cells", StemCells, vol. 26, no. 1, pp. 212-222, 2008.
9. G. M. Spaggiari, A. Capobianco, H. Abdelrazik, F. Becchetti, M. C. Mingari, and L. Moretta, "Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: role of indoleamine 2, 3-dioxygenase and prostaglandin E2", Blood, vol. 111, no. 3, pp. 1327-1333, 2008.
10. K. English, F. P. Barry, and B. P. Mahon, "Murine mesenchymal stem cells suppress dendritic cell migration, maturation and antigen presentation", Immunology Letters, vol. 115, no. 1, pp. 50-58, 2008.
11. H. K. Park, K. S. Cho, D. H. Shin et al., "Adipose-derived stromal cells inhibit allergic airway inflammation in mice", Stem Cells and Development, vol. 19, no. 11, pp. 1811-1818, 2010.
12. M. Goodwin, V. Sueblinvong, P. Eisenhauer et al., "Bone marrowderived mesenchymal stromal cells inhibit Th2-mediated allergic airways inflammation in mice", Stem Cells, vol. 29, no. 7, pp. 1137-1148, 2011.
13. T. L. Bonfield, M. Koloze, D. P. Lennon, B. Zuchowski, S. E. Yang, and A. I. Caplan, "Human mesenchymal stem cells suppress chronic airway inflammation in themurine ovalbumin asthma model", The American Journal of Physiology-Lung Cellular and Molecular Physiology, vol. 299, no. 6, pp. L760-L770, 2010.
14. Q. L. Fu, Y. Y. Chow, S. J. Sun et al., "Mesenchymal stem cells derived from human induced pluripotent stem cells modulate T-cell phenotypes in allergic rhinitis", Allergy, vol. 67, no. 10, pp. 1215-1222, 2012.
15. K.-S. Cho, H.-K. Park, H.-Y. Park et al., "IFATS collection: immunomodulatory effects of adipose tissue-derived stemcells in an allergic rhinitismouse model", StemCells, vol. 27, no. 1, pp. 259-265, 2009.
16. Y. Q. Sun, M. X. Deng, J. He et al., "Human pluripotent stem cell-derived mesenchymal stem cells prevent allergic airway inflammation in mice", StemCells, vol. 30, no. 12, pp. 2692-2699, 2012.
17. K. Cho and H. Roh, "Immunomodulatory effects of adiposederived stemcells in airway allergic diseases", Current Stem Cell Research and Therapy, vol. 5, no. 2, pp. 111-115, 2010.
18. + T cells induced by nasal application of ovalbumin transfer tolerance in a therapeuticmodel of asthma", International Immunology, vol. 23, no. 1, pp. 17-27, 2011.
19. H2-mediated sensitization and inflammation in the lung", Nature Medicine, vol. 10, no. 10, pp. 1095-1103, 2004.
20. K. G. Tournoy, J. C. Kips, C. Schou, and R. A. Pauwels, "Airway eosinophilia is not a requirement for allergen-induced airway hyperresponsiveness", Clinical and Experimental Allergy, vol. 30, no. 1, pp. 79-85, 2000.
21. H. K. Jin, S. K. Byung, G. U. Tae et al., "γ-secretase inhibitor reduces allergic pulmonary inflammation by modulating Th1 and Th2 responses", The American Journal of Respiratory and Critical Care Medicine, vol. 179, no. 10, pp. 875-882, 2009.
22. R. H. Lee, B. Kim, I. Choi et al., "Characterization and expression analysis of mesenchymal stem cells from human bone marrow and adipose tissue", Cellular Physiology and Biochemistry, vol. 14, no. 4-6, pp. 311-324, 2004.
23. B. Puissant, C. Barreau, P. Bourin et al., "Immunomodulatory effect of human adipose tissue-derived adult stem cells: comparisonwith bone marrowmesenchymal stem cells", British Journal of Haematology, vol. 129, no. 1, pp. 118-129, 2005.
24. H. Jang, K. Cho, H. Park, and H. Roh, "Adipose tissue-derived stem cells for cell therapy of airway allergic diseases in mouse", Acta Histochemica, vol. 113, no. 5, pp. 501-507, 2011.
25. V. Sueblinvong and D. J. Weiss, "Stem cells and cell therapy approaches in lung biology and diseases", Translational Research, vol. 156, no. 3, pp. 188-205, 2010.
26. G. Wang, B. A. Bunnell, R. G. Painter et al., "Adult stem cells from bone marrow stroma differentiate into airway epithelial cells: potential therapy for cystic fibrosis", Proceedings of the National Academy of Sciences of the United States of America, vol. 102, no. 1, pp. 186-191, 2005.
27. M. Mao, S. N. Wang, X. J. Lv, Y. Wang, and J. C. Xu, "Intravenous delivery of bone marrow-derived endothelial progenitor cells improves survival and attenuates lipopolysaccharide-induced lung injury in rats", Shock, vol. 34, no. 2, pp. 196-204, 2010.
28. R. Maccario, M. Podestà, A. Moretta et al., "Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype", Haematologica, vol. 90, no. 4, pp. 516-525, 2005.
29. A. Augello, R. Tasso, S. M. Negrini, R. Cancedda, and G. Pennesi, "Cell therapy using allogeneic bonemarrowmesenchymal stem cells prevents tissue damage in collagen-induced arthritis", Arthritis & Rheumatism, vol. 56, no. 4, pp. 1175-1186, 2007.
30. hi regulatory T cells in pediatric asthma", Journal of Allergy and Clinical Immunology, vol. 119, no. 5, pp. 1258-1266, 2007.
31. K. English, J. M. Ryan, L. Tobin, M. J. Murphy, F. P. Barry, and B. P. Mahon, "Cell contact, prostaglandin E2 and transforming growth factor beta 1 play non-redundant roles in human mesenchymal stem cell induction of CD4+CD25Highforkhead box P3+ regulatory T cells", Clinical and Experimental Immunology, vol. 156, no. 1, pp. 149-160, 2009.
32. R. Meisel, A. Zibert, M. Laryea, U. Göbel, W. Däubener, and D. Dilloo, "Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2, 3-dioxygenasemediated tryptophan degradation", Blood, vol. 103, no. 12, pp. 4619-4621, 2004.
33. K. Nemeth, A. Keane-Myers, J. M. Brown et al., "Bone marrow stromal cells use TGF-β to suppress allergic responses in a mouse model of ragweed-induced asthma", Proceedings of the National Academy of Sciences of the United States of America, vol. 107, no. 12, pp. 5652-5657, 2010.
34. M. D. Nicola, C. Carlo-Stella, M. Magni et al., "Human bone marrow stromal cells suppress T-lymphocyte proliferation induced by cellular or nonspecific mitogenic stimuli", Blood, vol. 99, no. 10, pp. 3838-3843, 2002.
35. S. Aggarwal and M. F. Pittenger, "Human mesenchymal stem cells modulate allogeneic immune cell responses", Blood, vol. 105, no. 4, pp. 1815-1822, 2005.
36. L. Cui, Y. Shuo, W. Liu, N. Li, W. Zhang, and Y. Cao, "Expanded adipose-derived stemcells suppress mixed lymphocyte reaction by secretion of prostaglandin E2", Tissue Engineering, vol. 13, no. 6, pp. 1185-1195, 2007.