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Volumn 50, Issue 6, 2015, Pages 770-780

Beyond consolidation: Auto-SCT and immunotherapy for plasma cell myeloma

Author keywords

[No Author keywords available]

Indexed keywords

B CELL MATURATION ANTIGEN; CANCER VACCINE; CHIMERIC ANTIGEN RECEPTOR; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; DENDRITIC CELL MYELOMA CELL FUSION VACCINE; DENDRITIC CELL VACCINE; DEXAMETHASONE; DURVALUMAB; FLUDARABINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HUMAN TELOMERASE REVERSE TRANSCRIPTASE SURVIVIN MULTIPEPTIDE VACCINE; IDIOTYPE KEYHOLE LIMPET HEMOCYANIN CONJUGATE VACCINE; INTERLEUKIN 2; IPILIMUMAB; LENALIDOMIDE; MELANOMA ANTIGEN 3; MELPHALAN; MPDL 3280A; NIVOLUMAB; PEMBROLIZUMAB; PEPTIDE VACCINE; PIDILIZUMAB; PNEUMOCOCCUS VACCINE; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; T LYMPHOCYTE RECEPTOR; TADALAFIL; TICILIMUMAB; UNCLASSIFIED DRUG; UNINDEXED DRUG; WT1 PEPTIDE VACCINE;

EID: 84930383040     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/bmt.2015.5     Document Type: Review
Times cited : (7)

References (108)
  • 1
    • 8944220233 scopus 로고    scopus 로고
    • A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome
    • Attal M, Harousseau JL, Stoppa AM, Sotto JJ, Fuzibet JG, Rossi JF, et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome. N Engl J Med 1996; 335: 91-97
    • (1996) N Engl J Med , vol.335 , pp. 91-97
    • Attal, M.1    Harousseau, J.L.2    Stoppa, A.M.3    Sotto, J.J.4    Fuzibet, J.G.5    Rossi, J.F.6
  • 2
    • 0037739753 scopus 로고    scopus 로고
    • High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma
    • Child JA, Morgan GJ, Davies FE, Owen RG, Bell SE, Hawkins K, et al. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med 2003; 348: 1875-1883
    • (2003) N Engl J Med , vol.348 , pp. 1875-1883
    • Child, J.A.1    Morgan, G.J.2    Davies, F.E.3    Owen, R.G.4    Bell, S.E.5    Hawkins, K.6
  • 3
    • 33846274225 scopus 로고    scopus 로고
    • Highdose therapy with single autologous transplantation versus chemotherapy for newly diagnosed multiple myeloma: A systematic review and meta-analysis of randomized controlled trials
    • Koreth J, Cutler CS, Djulbegovic B, Behl R, Schlossman RL, Munshi NC, et al. Highdose therapy with single autologous transplantation versus chemotherapy for newly diagnosed multiple myeloma: A systematic review and meta-analysis of randomized controlled trials. Biol Blood Marrow Transplant 2007; 13: 183-196
    • (2007) Biol Blood Marrow Transplant , vol.13 , pp. 183-196
    • Koreth, J.1    Cutler, C.S.2    Djulbegovic, B.3    Behl, R.4    Schlossman, R.L.5    Munshi, N.C.6
  • 4
    • 0034894245 scopus 로고    scopus 로고
    • Allogeneic hematopoietic cell transplantation for multiple myeloma
    • Bensinger WI, Maloney D, Storb R. Allogeneic hematopoietic cell transplantation for multiple myeloma. Semin Hematol 2001; 38: 243-249
    • (2001) Semin Hematol , vol.38 , pp. 243-249
    • Bensinger, W.I.1    Maloney, D.2    Storb, R.3
  • 5
    • 0026070258 scopus 로고
    • Allogeneic bone marrow transplantation in multiple myeloma european group for bone marrow transplantation
    • Gahrton G, Tura S, Ljungman P, Belanger C, Brandt L, Cavo M, et al. Allogeneic bone marrow transplantation in multiple myeloma. European Group for Bone Marrow Transplantation. N Engl J Med 1991; 325: 1267-1273
    • (1991) N Engl J Med , vol.325 , pp. 1267-1273
    • Gahrton, G.1    Tura, S.2    Ljungman, P.3    Belanger, C.4    Brandt, L.5    Cavo, M.6
  • 6
    • 0029822773 scopus 로고    scopus 로고
    • Allogeneic marrow transplantation for multiple myeloma: An analysis of risk factors on outcome
    • Bensinger WI, Buckner CD, Anasetti C, Clift R, Storb R, Barnett T, et al. Allogeneic marrow transplantation for multiple myeloma: an analysis of risk factors on outcome. Blood 1996; 88: 2787-2793
    • (1996) Blood , vol.88 , pp. 2787-2793
    • Bensinger, W.I.1    Buckner, C.D.2    Anasetti, C.3    Clift, R.4    Storb, R.5    Barnett, T.6
  • 7
    • 21144446701 scopus 로고    scopus 로고
    • Outcomes for reduced-intensity allogeneic transplantation for multiple myeloma: An analysis of prognostic factors from the chronic leukaemia working party of the ebmt
    • Crawley C, Lalancette M, Szydlo R, Gilleece M, Peggs K, Mackinnon S, et al. Outcomes for reduced-intensity allogeneic transplantation for multiple myeloma: an analysis of prognostic factors from the Chronic Leukaemia Working Party of the EBMT. Blood 2005; 105: 4532-4539
    • (2005) Blood , vol.105 , pp. 4532-4539
    • Crawley, C.1    Lalancette, M.2    Szydlo, R.3    Gilleece, M.4    Peggs, K.5    MacKinnon, S.6
  • 8
    • 0346878828 scopus 로고    scopus 로고
    • Long-term follow-up of T cell-depleted allogeneic bone marrow transplantation in refractory multiple myeloma: Importance of allogeneic T cells
    • Huff CA, Fuchs EJ, Noga SJ, O'Donnell PV, Ambinder RF, Diehl L, et al. Long-term follow-up of T cell-depleted allogeneic bone marrow transplantation in refractory multiple myeloma: importance of allogeneic T cells. Biol Blood Marrow Transplant 2003; 9: 312-319
    • (2003) Biol Blood Marrow Transplant , vol.9 , pp. 312-319
    • Huff, C.A.1    Fuchs, E.J.2    Noga, S.J.3    O'Donnell, P.V.4    Ambinder, R.F.5    Diehl, L.6
  • 9
    • 8644231815 scopus 로고    scopus 로고
    • Low-dose thalidomide and donor lymphocyte infusion as adoptive immunotherapy after allogeneic stem cell transplantation in patients with multiple myeloma
    • Kroger N, Shimoni A, Zagrivnaja M, Ayuk F, Lioznov M, Schieder H, et al. Low-dose thalidomide and donor lymphocyte infusion as adoptive immunotherapy after allogeneic stem cell transplantation in patients with multiple myeloma. Blood 2004; 104: 3361-3363
    • (2004) Blood , vol.104 , pp. 3361-3363
    • Kroger, N.1    Shimoni, A.2    Zagrivnaja, M.3    Ayuk, F.4    Lioznov, M.5    Schieder, H.6
  • 10
    • 0038543513 scopus 로고    scopus 로고
    • A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma
    • Dhodapkar MV, Geller MD, Chang DH, Shimizu K, Fujii S, Dhodapkar KM, et al. A reversible defect in natural killer T cell function characterizes the progression of premalignant to malignant multiple myeloma. J Exp Med 2003; 197: 1667-1676
    • (2003) J Exp Med , vol.197 , pp. 1667-1676
    • Dhodapkar, M.V.1    Geller, M.D.2    Chang, D.H.3    Shimizu, K.4    Fujii, S.5    Dhodapkar, K.M.6
  • 11
    • 0345599884 scopus 로고    scopus 로고
    • Vigorous premalignancyspecific effector T cell response in the bone marrow of patients with monoclonal gammopathy
    • Dhodapkar MV, Krasovsky J, Osman K, Geller MD. Vigorous premalignancyspecific effector T cell response in the bone marrow of patients with monoclonal gammopathy. J Exp Med 2003; 198: 1753-1757
    • (2003) J Exp Med , vol.198 , pp. 1753-1757
    • Dhodapkar, M.V.1    Krasovsky, J.2    Osman, K.3    Geller, M.D.4
  • 12
    • 0036789934 scopus 로고    scopus 로고
    • T cells from the tumor microenvironment of patients with progressive myeloma can generate strong, tumor-specific cytolytic responses to autologous, tumor-loaded dendritic cells
    • Dhodapkar MV, Krasovsky J, Olson K. T cells from the tumor microenvironment of patients with progressive myeloma can generate strong, tumor-specific cytolytic responses to autologous, tumor-loaded dendritic cells. Proc Natl Acad Sci USA 2002; 99: 13009-13013
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 13009-13013
    • Dhodapkar, M.V.1    Krasovsky, J.2    Olson, K.3
  • 13
    • 20144389307 scopus 로고    scopus 로고
    • Activated marrowinfiltrating lymphocytes effectively target plasma cells and their clonogenic precursors
    • Noonan K, Matsui W, Serafini P, Carbley R, Tan G, Khalili J, et al. Activated marrowinfiltrating lymphocytes effectively target plasma cells and their clonogenic precursors. Cancer Res 2005; 65: 2026-2034
    • (2005) Cancer Res , vol.65 , pp. 2026-2034
    • Noonan, K.1    Matsui, W.2    Serafini, P.3    Carbley, R.4    Tan, G.5    Khalili, J.6
  • 14
    • 33846871255 scopus 로고    scopus 로고
    • Cancer-testis antigens are commonly expressed in multiple myeloma and induce systemic immunity following allogeneic stem cell transplantation
    • Atanackovic D, Arfsten J, Cao Y, Gnjatic S, Schnieders F, Bartels K, et al. Cancer-testis antigens are commonly expressed in multiple myeloma and induce systemic immunity following allogeneic stem cell transplantation. Blood 2007; 109: 1103-1112
    • (2007) Blood , vol.109 , pp. 1103-1112
    • Atanackovic, D.1    Arfsten, J.2    Cao, Y.3    Gnjatic, S.4    Schnieders, F.5    Bartels, K.6
  • 15
    • 28844462429 scopus 로고    scopus 로고
    • CD8+T cells specific for cancer germline gene antigens are found in many patients with multiple myeloma, and their frequency correlates with disease burden
    • Goodyear O, Piper K, Khan N, Starczynski J, Mahendra P, Pratt G, et al. CD8+T cells specific for cancer germline gene antigens are found in many patients with multiple myeloma, and their frequency correlates with disease burden. Blood 2005; 106: 4217-4224
    • (2005) Blood , vol.106 , pp. 4217-4224
    • Goodyear, O.1    Piper, K.2    Khan, N.3    Starczynski, J.4    Mahendra, P.5    Pratt, G.6
  • 16
    • 20844432364 scopus 로고    scopus 로고
    • Ny-eso-1 is highly expressed in poor-prognosis multiple myeloma and induces spontaneous humoral and cellular immune responses
    • van Rhee F, Szmania SM, Zhan F, Gupta SK, Pomtree M, Lin P, et al. NY-ESO-1 is highly expressed in poor-prognosis multiple myeloma and induces spontaneous humoral and cellular immune responses. Blood 2005; 105: 3939-3944
    • (2005) Blood , vol.105 , pp. 3939-3944
    • Van Rhee, F.1    Szmania, S.M.2    Zhan, F.3    Gupta, S.K.4    Pomtree, M.5    Lin, P.6
  • 17
    • 77957701558 scopus 로고    scopus 로고
    • The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: A therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody
    • Benson DM Jr, Bakan CE, Mishra A, Hofmeister CC, Efebera Y, Becknell B, et al. The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody. Blood 2010; 116: 2286-2294
    • (2010) Blood , vol.116 , pp. 2286-2294
    • Benson, D.M.1    Bakan, C.E.2    Mishra, A.3    Hofmeister, C.C.4    Efebera, Y.5    Becknell, B.6
  • 18
    • 58149232585 scopus 로고    scopus 로고
    • Therapeutic antitumor efficacy of anti-CD137 agonistic monoclonal antibody in mouse models of myeloma
    • Murillo O, Arina A, Hervas-Stubbs S, Gupta A, McCluskey B, Dubrot J, et al. Therapeutic antitumor efficacy of anti-CD137 agonistic monoclonal antibody in mouse models of myeloma. Clin Cancer Res 2008; 14: 6895-6906
    • (2008) Clin Cancer Res , vol.14 , pp. 6895-6906
    • Murillo, O.1    Arina, A.2    Hervas-Stubbs, S.3    Gupta, A.4    McCluskey, B.5    Dubrot, J.6
  • 19
    • 0025314873 scopus 로고
    • T-cell-depleted autologous bone marrow transplantation therapy: Analysis of immune deficiency and late complications
    • Anderson KC, Soiffer R, DeLage R, Takvorian T, Freedman AS, Rabinowe SL, et al. T-cell-depleted autologous bone marrow transplantation therapy: analysis of immune deficiency and late complications. Blood 1990; 76: 235-244
    • (1990) Blood , vol.76 , pp. 235-244
    • Anderson, K.C.1    Soiffer, R.2    Delage, R.3    Takvorian, T.4    Freedman, A.S.5    Rabinowe, S.L.6
  • 20
    • 0032170052 scopus 로고    scopus 로고
    • Immune reconstitution and immunotherapy after autologous hematopoietic stem cell transplantation
    • Guillaume T, Rubinstein DB, Symann M. Immune reconstitution and immunotherapy after autologous hematopoietic stem cell transplantation. Blood 1998; 92: 1471-1490
    • (1998) Blood , vol.92 , pp. 1471-1490
    • Guillaume, T.1    Rubinstein, D.B.2    Symann, M.3
  • 21
    • 78751699860 scopus 로고    scopus 로고
    • Combination immunotherapy using adoptive t-cell transfer and tumor antigen vaccination on the basis of htert and survivin after asct for myeloma
    • Rapoport AP, Aqui NA, Stadtmauer EA, Vogl DT, Fang HB, Cai L, et al. Combination immunotherapy using adoptive T-cell transfer and tumor antigen vaccination on the basis of hTERT and survivin after ASCT for myeloma. Blood 2011; 117: 788-797
    • (2011) Blood , vol.117 , pp. 788-797
    • Rapoport, A.P.1    Aqui, N.A.2    Stadtmauer, E.A.3    Vogl, D.T.4    Fang, H.B.5    Cai, L.6
  • 22
    • 30744454570 scopus 로고    scopus 로고
    • Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer
    • Rapoport AP, Stadtmauer EA, Aqui N, Badros A, Cotte J, Chrisley L, et al. Restoration of immunity in lymphopenic individuals with cancer by vaccination and adoptive T-cell transfer. Nat Med 2005; 11: 1230-1237
    • (2005) Nat Med , vol.11 , pp. 1230-1237
    • Rapoport, A.P.1    Stadtmauer, E.A.2    Aqui, N.3    Badros, A.4    Cotte, J.5    Chrisley, L.6
  • 23
    • 34547686398 scopus 로고    scopus 로고
    • Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling
    • Paulos CM, Wrzesinski C, Kaiser A, Hinrichs CS, Chieppa M, Cassard L, et al. Microbial translocation augments the function of adoptively transferred self/tumor-specific CD8+ T cells via TLR4 signaling. J Clin Invest 2007; 117: 2197-2204
    • (2007) J Clin Invest , vol.117 , pp. 2197-2204
    • Paulos, C.M.1    Wrzesinski, C.2    Kaiser, A.3    Hinrichs, C.S.4    Chieppa, M.5    Cassard, L.6
  • 24
    • 33846429184 scopus 로고    scopus 로고
    • Induced sensitization of tumor stroma leads to eradication of established cancer by T cells
    • Zhang B, Bowerman NA, Salama JK, Schmidt H, Spiotto MT, Schietinger A, et al. Induced sensitization of tumor stroma leads to eradication of established cancer by T cells. J Exp Med 2007; 204: 49-55
    • (2007) J Exp Med , vol.204 , pp. 49-55
    • Zhang, B.1    Bowerman, N.A.2    Salama, J.K.3    Schmidt, H.4    Spiotto, M.T.5    Schietinger, A.6
  • 25
    • 25844484607 scopus 로고    scopus 로고
    • Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells
    • Gattinoni L, Finkelstein SE, Klebanoff CA, Antony PA, Palmer DC, Spiess PJ, et al. Removal of homeostatic cytokine sinks by lymphodepletion enhances the efficacy of adoptively transferred tumor-specific CD8+ T cells. J Exp Med 2005; 202: 907-912
    • (2005) J Exp Med , vol.202 , pp. 907-912
    • Gattinoni, L.1    Finkelstein, S.E.2    Klebanoff, C.A.3    Antony, P.A.4    Palmer, D.C.5    Spiess, P.J.6
  • 26
    • 33846787125 scopus 로고    scopus 로고
    • Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8 T cells
    • Wrzesinski C, Paulos CM, Gattinoni L, Palmer DC, Kaiser A, Yu Z, et al. Hematopoietic stem cells promote the expansion and function of adoptively transferred antitumor CD8 T cells. J Clin Invest 2007; 117: 492-501
    • (2007) J Clin Invest , vol.117 , pp. 492-501
    • Wrzesinski, C.1    Paulos, C.M.2    Gattinoni, L.3    Palmer, D.C.4    Kaiser, A.5    Yu, Z.6
  • 27
    • 55949125601 scopus 로고    scopus 로고
    • Adoptive cell therapy for patients with metastatic melanoma: Evaluation of intensive myeloablative chemoradiation preparative regimens
    • Dudley ME, Yang JC, Sherry R, Hughes MS, Royal R, Kammula U, et al. Adoptive cell therapy for patients with metastatic melanoma: evaluation of intensive myeloablative chemoradiation preparative regimens. J Clin Oncol 2008; 26: 5233-5239
    • (2008) J Clin Oncol , vol.26 , pp. 5233-5239
    • Dudley, M.E.1    Yang, J.C.2    Sherry, R.3    Hughes, M.S.4    Royal, R.5    Kammula, U.6
  • 28
    • 0036301503 scopus 로고    scopus 로고
    • CTLA-4: New insights into its biological function and use in tumor immunotherapy
    • Egen JG, Kuhns MS, Allison JP. CTLA-4: new insights into its biological function and use in tumor immunotherapy. Nat Immunol 2002; 3: 611-618
    • (2002) Nat Immunol , vol.3 , pp. 611-618
    • Egen, J.G.1    Kuhns, M.S.2    Allison, J.P.3
  • 29
    • 84880511594 scopus 로고    scopus 로고
    • Development of ipilimumab: A novel immunotherapeutic approach for the treatment of advanced melanoma
    • Wolchok JD, Hodi FS, Weber JS, Allison JP, Urba WJ, Robert C, et al. Development of ipilimumab: a novel immunotherapeutic approach for the treatment of advanced melanoma. Ann NY Acad Sci 2013; 1291: 1-13
    • (2013) Ann NY Acad Sci , vol.1291 , pp. 1-13
    • Wolchok, J.D.1    Hodi, F.S.2    Weber, J.S.3    Allison, J.P.4    Urba, W.J.5    Robert, C.6
  • 31
    • 79959772576 scopus 로고    scopus 로고
    • Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
    • Robert C, Thomas L, Bondarenko I, O'Day S M DJ, Garbe C, et al. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 2011; 364: 2517-2526
    • (2011) N Engl J Med , vol.364 , pp. 2517-2526
    • Robert, C.1    Thomas, L.2    Bondarenko, I.3    O'Day, S.M.D.J.4    Garbe, C.5
  • 32
    • 84906939784 scopus 로고    scopus 로고
    • Enhancement of tumor-reactive cytotoxic CD4+ T cell responses after ipilimumab treatment in four advanced melanoma patients
    • Kitano S, Tsuji T, Liu C, Hirschhorn-Cymerman D, Kyi C, Mu Z, et al. Enhancement of tumor-reactive cytotoxic CD4+ T cell responses after ipilimumab treatment in four advanced melanoma patients. Cancer Immunol Res 2013; 1: 235-244
    • (2013) Cancer Immunol Res , vol.1 , pp. 235-244
    • Kitano, S.1    Tsuji, T.2    Liu, C.3    Hirschhorn-Cymerman, D.4    Kyi, C.5    Mu, Z.6
  • 34
    • 84155163015 scopus 로고    scopus 로고
    • Ipilimumab increases activated T cells and enhances humoral immunity in patients with advanced melanoma
    • Weber JS, Hamid O, Chasalow SD, Wu DY, Parker SM, Galbraith S, et al. Ipilimumab increases activated T cells and enhances humoral immunity in patients with advanced melanoma. J Immunother 2012; 35: 89-97
    • (2012) J Immunother , vol.35 , pp. 89-97
    • Weber, J.S.1    Hamid, O.2    Chasalow, S.D.3    Wu, D.Y.4    Parker, S.M.5    Galbraith, S.6
  • 36
    • 84859158384 scopus 로고    scopus 로고
    • Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity
    • Topalian SL, Drake CG, Pardoll DM. Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity. Curr Opin Immunol 2012; 24: 207-212
    • (2012) Curr Opin Immunol , vol.24 , pp. 207-212
    • Topalian, S.L.1    Drake, C.G.2    Pardoll, D.M.3
  • 37
    • 84879759020 scopus 로고    scopus 로고
    • Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma
    • Hamid O, Robert C, Daud A, Hodi FS, Hwu WJ, Kefford R, et al. Safety and tumor responses with lambrolizumab (anti-PD-1) in melanoma. N Engl J Med 2013; 369: 134-144
    • (2013) N Engl J Med , vol.369 , pp. 134-144
    • Hamid, O.1    Robert, C.2    Daud, A.3    Hodi, F.S.4    Hwu, W.J.5    Kefford, R.6
  • 38
    • 84908354848 scopus 로고    scopus 로고
    • Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: A randomised dose-comparison cohort of a phase 1 trial
    • Robert C, Ribas A, Wolchok JD, Hodi FS, Hamid O, Kefford R, et al. Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: a randomised dose-comparison cohort of a phase 1 trial. Lancet 2014; 384: 1109-1117
    • (2014) Lancet , vol.384 , pp. 1109-1117
    • Robert, C.1    Ribas, A.2    Wolchok, J.D.3    Hodi, F.S.4    Hamid, O.5    Kefford, R.6
  • 41
    • 84890096527 scopus 로고    scopus 로고
    • Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: Results of an international phase II trial
    • Armand P, Nagler A, Weller EA, Devine SM, Avigan DE, Chen YB, et al. Disabling immune tolerance by programmed death-1 blockade with pidilizumab after autologous hematopoietic stem-cell transplantation for diffuse large B-cell lymphoma: results of an international phase II trial. J Clin Oncol 2013; 31: 4199-4206
    • (2013) J Clin Oncol , vol.31 , pp. 4199-4206
    • Armand, P.1    Nagler, A.2    Weller, E.A.3    Devine, S.M.4    Avigan, D.E.5    Chen, Y.B.6
  • 42
    • 0037126021 scopus 로고    scopus 로고
    • Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
    • Iwai Y, Ishida M, Tanaka Y, Okazaki T, Honjo T, Minato N. Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade. Proc Natl Acad Sci USA 2002; 99: 12293-12297
    • (2002) Proc Natl Acad Sci USA , vol.99 , pp. 12293-12297
    • Iwai, Y.1    Ishida, M.2    Tanaka, Y.3    Okazaki, T.4    Honjo, T.5    Minato, N.6
  • 43
    • 34347400169 scopus 로고    scopus 로고
    • Plasma cells from multiple myeloma patients express b7-h1 (pd-l1) and increase expression after stimulation with ifn-{gamma} and tlr ligands via a myd88-, traf6-, and mek-dependent pathway
    • Liu J, Hamrouni A, Wolowiec D, Coiteux V, Kuliczkowski K, Hetuin D, et al. Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway. Blood 2007; 110: 296-304
    • (2007) Blood , vol.110 , pp. 296-304
    • Liu, J.1    Hamrouni, A.2    Wolowiec, D.3    Coiteux, V.4    Kuliczkowski, K.5    Hetuin, D.6
  • 44
    • 79957891364 scopus 로고    scopus 로고
    • PD-1 blockade by CT-011, anti-PD-1 antibody, enhances ex vivo T-cell responses to autologous dendritic cell/myeloma fusion vaccine
    • Rosenblatt J, Glotzbecker B, Mills H, Vasir B, Tzachanis D, Levine JD, et al. PD-1 blockade by CT-011, anti-PD-1 antibody, enhances ex vivo T-cell responses to autologous dendritic cell/myeloma fusion vaccine. J Immunother 2011; 34: 409-418
    • (2011) J Immunother , vol.34 , pp. 409-418
    • Rosenblatt, J.1    Glotzbecker, B.2    Mills, H.3    Vasir, B.4    Tzachanis, D.5    Levine, J.D.6
  • 45
    • 84873569613 scopus 로고    scopus 로고
    • Marrow stromal cells induce B7-H1 expression on myeloma cells, generating aggressive characteristics in multiple myeloma
    • Tamura H, Ishibashi M, Yamashita T, Tanosaki S, Okuyama N, Kondo A, et al. Marrow stromal cells induce B7-H1 expression on myeloma cells, generating aggressive characteristics in multiple myeloma. Leukemia 2013; 27: 464-472
    • (2013) Leukemia , vol.27 , pp. 464-472
    • Tamura, H.1    Ishibashi, M.2    Yamashita, T.3    Tanosaki, S.4    Okuyama, N.5    Kondo, A.6
  • 47
    • 84878099006 scopus 로고    scopus 로고
    • Programmed death receptor-1/programmed death receptor ligand-1 blockade after transient lymphodepletion to treat myeloma
    • Kearl TJ, Jing W, Gershan JA, Johnson BD. Programmed death receptor-1/programmed death receptor ligand-1 blockade after transient lymphodepletion to treat myeloma. J Immunol 2013; 190: 5620-5628
    • (2013) J Immunol , vol.190 , pp. 5620-5628
    • Kearl, T.J.1    Jing, W.2    Gershan, J.A.3    Johnson, B.D.4
  • 49
    • 44849109375 scopus 로고    scopus 로고
    • Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation
    • Bijker MS, van den Eeden SJ, Franken KL, Melief CJ, Van Der Burg SH, Offringa R. Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation. Eur J Immunol 2008; 38: 1033-1042
    • (2008) Eur J Immunol , vol.38 , pp. 1033-1042
    • Bijker, M.S.1    Van Den Eeden, S.J.2    Franken, K.L.3    Melief, C.J.4    Van Der Burg, S.H.5    Offringa, R.6
  • 51
    • 0035879093 scopus 로고    scopus 로고
    • Identification of new epitopes from four different tumor-associated antigens: Recognition of naturally processed epitopes correlates with hla-A∗0201-binding affinity
    • Keogh E, Fikes J, Southwood S, Celis E, Chesnut R, Sette A. Identification of new epitopes from four different tumor-associated antigens: recognition of naturally processed epitopes correlates with HLA-A∗0201-binding affinity. J Immunol 2001; 167: 787-796
    • (2001) J Immunol , vol.167 , pp. 787-796
    • Keogh, E.1    Fikes, J.2    Southwood, S.3    Celis, E.4    Chesnut, R.5    Sette, A.6
  • 52
    • 0030587077 scopus 로고    scopus 로고
    • Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A∗0201-binding residues
    • Parkhurst MR, Salgaller ML, Southwood S, Robbins PF, Sette A, Rosenberg SA, et al. Improved induction of melanoma-reactive CTL with peptides from the melanoma antigen gp100 modified at HLA-A∗0201-binding residues. J Immunol 1996; 157: 2539-2548
    • (1996) J Immunol , vol.157 , pp. 2539-2548
    • Parkhurst, M.R.1    Salgaller, M.L.2    Southwood, S.3    Robbins, P.F.4    Sette, A.5    Rosenberg, S.A.6
  • 53
    • 27144520232 scopus 로고    scopus 로고
    • Synthetic peptide analogs derived from bcr/abl fusion proteins and the induction of heteroclitic human T-cell responses
    • Pinilla-Ibarz J, Korontsvit T, Zakhaleva V, Roberts W, Scheinberg DA. Synthetic peptide analogs derived from bcr/abl fusion proteins and the induction of heteroclitic human T-cell responses. Haematologica 2005; 90: 1324-1332
    • (2005) Haematologica , vol.90 , pp. 1324-1332
    • Pinilla-Ibarz, J.1    Korontsvit, T.2    Zakhaleva, V.3    Roberts, W.4    Scheinberg, D.A.5
  • 54
    • 0035903287 scopus 로고    scopus 로고
    • Structural features of peptide analogs of human histocompatibility leukocyte antigen class i epitopes that are more potent and immunogenic than wild-type peptide
    • Tangri S, Ishioka GY, Huang X, Sidney J, Southwood S, Fikes J, et al. Structural features of peptide analogs of human histocompatibility leukocyte antigen class I epitopes that are more potent and immunogenic than wild-type peptide. J Exp Med 2001; 194: 833-846
    • (2001) J Exp Med , vol.194 , pp. 833-846
    • Tangri, S.1    Ishioka, G.Y.2    Huang, X.3    Sidney, J.4    Southwood, S.5    Fikes, J.6
  • 55
    • 0034661697 scopus 로고    scopus 로고
    • Identification of NY-ESO-1 peptide analogues capable of improved stimulation of tumorreactive CTL
    • Chen JL, Dunbar PR, Gileadi U, Jager E, Gnjatic S, Nagata Y, et al. Identification of NY-ESO-1 peptide analogues capable of improved stimulation of tumorreactive CTL. J Immunol 2000; 165: 948-955
    • (2000) J Immunol , vol.165 , pp. 948-955
    • Chen, J.L.1    Dunbar, P.R.2    Gileadi, U.3    Jager, E.4    Gnjatic, S.5    Nagata, Y.6
  • 56
    • 84872299047 scopus 로고    scopus 로고
    • Wt1-specific t-cell responses in high-risk multiple myeloma patients undergoing allogeneic t cell-depleted hematopoietic stem cell transplantation and donor lymphocyte infusions
    • Tyler EM, Jungbluth AA, O'Reilly RJ, Koehne G. WT1-specific T-cell responses in high-risk multiple myeloma patients undergoing allogeneic T cell-depleted hematopoietic stem cell transplantation and donor lymphocyte infusions. Blood 2013; 121: 308-317
    • (2013) Blood , vol.121 , pp. 308-317
    • Tyler, E.M.1    Jungbluth, A.A.2    O'Reilly, R.J.3    Koehne, G.4
  • 57
    • 84925132076 scopus 로고    scopus 로고
    • Phase I/II study exploring immucin, a pan-major histocompatibility complex, anti-muc1 signal peptide vaccine, in multiple myeloma patients
    • epub ahead of print 11 December
    • Carmon L, Avivi I, Kovjazin R, Zuckerman T, Dary L, Gatt ME, et al. Phase I/II study exploring ImMucin, a pan-major histocompatibility complex, anti-MUC1 signal peptide vaccine, in multiple myeloma patients. Br J Haematol (epub ahead of print 11 December 2014; doi:10.1111/bjh.13245
    • (2014) Br J Haematol
    • Carmon, L.1    Avivi, I.2    Kovjazin, R.3    Zuckerman, T.4    Dary, L.5    Gatt, M.E.6
  • 58
    • 0033120389 scopus 로고    scopus 로고
    • Idiotype vaccination using dendritic cells after autologous peripheral blood stem cell transplantation for multiple myeloma-A feasibility study
    • Reichardt VL, Okada CY, Liso A, Benike CJ, Stockerl-Goldstein KE, Engleman EG, et al. Idiotype vaccination using dendritic cells after autologous peripheral blood stem cell transplantation for multiple myeloma-a feasibility study. Blood 1999; 93: 2411-2419
    • (1999) Blood , vol.93 , pp. 2411-2419
    • Reichardt, V.L.1    Okada, C.Y.2    Liso, A.3    Benike, C.J.4    Stockerl-Goldstein, K.E.5    Engleman, E.G.6
  • 60
    • 73349121252 scopus 로고    scopus 로고
    • Idiotypepulsed antigen-presenting cells following autologous transplantation for multiple myeloma may be associated with prolonged survival
    • Lacy MQ, Mandrekar S, Dispenzieri A, Hayman S, Kumar S, Buadi F, et al. Idiotypepulsed antigen-presenting cells following autologous transplantation for multiple myeloma may be associated with prolonged survival. Am J Hematol 2009; 84: 799-802
    • (2009) Am J Hematol , vol.84 , pp. 799-802
    • Lacy, M.Q.1    Mandrekar, S.2    Dispenzieri, A.3    Hayman, S.4    Kumar, S.5    Buadi, F.6
  • 61
    • 84879863520 scopus 로고    scopus 로고
    • Vaccination with dendritic cell/tumor fusions following autologous stem cell transplant induces immunologic and clinical responses in multiple myeloma patients
    • Rosenblatt J, Avivi I, Vasir B, Uhl L, Munshi NC, Katz T, et al. Vaccination with dendritic cell/tumor fusions following autologous stem cell transplant induces immunologic and clinical responses in multiple myeloma patients. Clin Cancer Res 2013; 19: 3640-3648
    • (2013) Clin Cancer Res , vol.19 , pp. 3640-3648
    • Rosenblatt, J.1    Avivi, I.2    Vasir, B.3    Uhl, L.4    Munshi, N.C.5    Katz, T.6
  • 62
    • 79957891364 scopus 로고    scopus 로고
    • PD-1 blockade by CT-011, anti-PD-1 antibody, enhances ex vivo T-cell responses to autologous dendritic cell/myeloma fusion vaccine
    • Rosenblatt J, Glotzbecker B, Mills H, Vasir B, Tzachanis D, Levine JD, et al. PD-1 blockade by CT-011, anti-PD-1 antibody, enhances ex vivo T-cell responses to autologous dendritic cell/myeloma fusion vaccine. J Immunother 2011; 34: 409-418
    • (2011) J Immunother , vol.34 , pp. 409-418
    • Rosenblatt, J.1    Glotzbecker, B.2    Mills, H.3    Vasir, B.4    Tzachanis, D.5    Levine, J.D.6
  • 63
    • 84879559198 scopus 로고    scopus 로고
    • Blockade of PD-1 in combination with dendritic cell/myeloma fusion cell vaccination following autologous stem cell transplantation
    • Rosenblatt J, Avivi I, Vasir D, Uhl L, Katz T, Somaiya P, et al. Blockade of PD-1 in combination with dendritic cell/myeloma fusion cell vaccination following autologous stem cell transplantation. Biol Blood Marrow Transplant 2013; 19: S109-S109
    • (2013) Biol Blood Marrow Transplant , vol.19 , pp. S109-S109
    • Rosenblatt, J.1    Avivi, I.2    Vasir, D.3    Uhl, L.4    Katz, T.5    Somaiya, P.6
  • 64
    • 84895813363 scopus 로고    scopus 로고
    • Combination immunotherapy after asct for multiple myeloma using mage-a3/poly-iclc immunizations followed by adoptive transfer of vaccine-primed and costimulated autologous t cells
    • Rapoport AP, Aqui NA, Stadtmauer EA, Vogl DT, Xu YY, Kalos M, et al. Combination immunotherapy after ASCT for multiple myeloma using MAGE-A3/Poly-ICLC immunizations followed by adoptive transfer of vaccine-primed and costimulated autologous T cells. Clin Cancer Res 2014; 20: 1355-1365
    • (2014) Clin Cancer Res , vol.20 , pp. 1355-1365
    • Rapoport, A.P.1    Aqui, N.A.2    Stadtmauer, E.A.3    Vogl, D.T.4    Xu, Y.Y.5    Kalos, M.6
  • 65
    • 84922539901 scopus 로고    scopus 로고
    • Mage-a3 recombinant protein (recmage-a3) immunotherapy and autologous peripheral blood lymphocyte (pbl) infusion is safe and induces robust humoral immune responses in multiple myeloma (mm) patients undergoing autologous stem cell transplantation (autosct
    • Cohen AD, Lendvai N, Gnjatic S, Jungbluth AA, Bertolini S, Pan L, et al. MAGE-A3 recombinant protein (recMAGE-A3) immunotherapy and autologous peripheral blood lymphocyte (PBL) infusion is safe and induces robust humoral immune responses in multiple myeloma (MM) patients undergoing autologous stem cell transplantation (autoSCT). J Clin Oncol 2013; 122: 154-154
    • (2013) J Clin Oncol , vol.122 , pp. 154-154
    • Cohen, A.D.1    Lendvai, N.2    Gnjatic, S.3    Jungbluth, A.A.4    Bertolini, S.5    Pan, L.6
  • 67
    • 33751531874 scopus 로고    scopus 로고
    • Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function
    • Serafini P, Meckel K, Kelso M, Noonan K, Califano J, Koch W, et al. Phosphodiesterase-5 inhibition augments endogenous antitumor immunity by reducing myeloid-derived suppressor cell function. J Exp Med 2006; 203: 2691-2702
    • (2006) J Exp Med , vol.203 , pp. 2691-2702
    • Serafini, P.1    Meckel, K.2    Kelso, M.3    Noonan, K.4    Califano, J.5    Koch, W.6
  • 68
    • 84875442375 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cells regulate growth of multiple myeloma by inhibiting T cells in bone marrow
    • Ramachandran IR, Martner A, Pisklakova A, Condamine T, Chase T, Vogl T, et al. Myeloid-derived suppressor cells regulate growth of multiple myeloma by inhibiting T cells in bone marrow. J Immunol 2013; 190: 3815-3823
    • (2013) J Immunol , vol.190 , pp. 3815-3823
    • Ramachandran, I.R.1    Martner, A.2    Pisklakova, A.3    Condamine, T.4    Chase, T.5    Vogl, T.6
  • 69
    • 80054016181 scopus 로고    scopus 로고
    • Donor KIR haplotype B improves progression-free and overall survival after allogeneic hematopoietic stem cell transplantation for multiple myeloma
    • Kroger N, Zabelina T, Berger J, Duske H, Klyuchnikov E, Binder T, et al. Donor KIR haplotype B improves progression-free and overall survival after allogeneic hematopoietic stem cell transplantation for multiple myeloma. Leukemia 2011; 25: 1657-1661
    • (2011) Leukemia , vol.25 , pp. 1657-1661
    • Kroger, N.1    Zabelina, T.2    Berger, J.3    Duske, H.4    Klyuchnikov, E.5    Binder, T.6
  • 70
    • 84901290331 scopus 로고    scopus 로고
    • Donor killer cell Ig-like receptor B haplotypes, recipient HLA-C1, and HLA-C mismatch enhance the clinical benefit of unrelated transplantation for acute myelogenous leukemia
    • Cooley S, Weisdorf DJ, Guethlein LA, Klein JP, Wang T, Marsh SG, et al. Donor killer cell Ig-like receptor B haplotypes, recipient HLA-C1, and HLA-C mismatch enhance the clinical benefit of unrelated transplantation for acute myelogenous leukemia. J Immunol 2014; 192: 4592-4600
    • (2014) J Immunol , vol.192 , pp. 4592-4600
    • Cooley, S.1    Weisdorf, D.J.2    Guethlein, L.A.3    Klein, J.P.4    Wang, T.5    Marsh, S.G.6
  • 71
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
    • Ruggeri L, Capanni M, Urbani E, Perruccio K, Shlomchik WD, Tosti A, et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 2002; 295: 2097-2100
    • (2002) Science , vol.295 , pp. 2097-2100
    • Ruggeri, L.1    Capanni, M.2    Urbani, E.3    Perruccio, K.4    Shlomchik, W.D.5    Tosti, A.6
  • 72
    • 55949134663 scopus 로고    scopus 로고
    • Infusion of haplo-identical killer immunoglobulin-like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation
    • Shi J, Tricot G, Szmania S, Rosen N, Garg TK, Malaviarachchi PA, et al. Infusion of haplo-identical killer immunoglobulin-like receptor ligand mismatched NK cells for relapsed myeloma in the setting of autologous stem cell transplantation. Br J Haematol 2008; 143: 641-653
    • (2008) Br J Haematol , vol.143 , pp. 641-653
    • Shi, J.1    Tricot, G.2    Szmania, S.3    Rosen, N.4    Garg, T.K.5    Malaviarachchi, P.A.6
  • 74
    • 77957300466 scopus 로고    scopus 로고
    • Good manufacturing practice-compliant cell sorting and large-scale expansion of single KIR-positive alloreactive human natural killer cells for multiple infusions to leukemia patients
    • Siegler U, Meyer-Monard S, Jorger S, Stern M, Tichelli A, Gratwohl A, et al. Good manufacturing practice-compliant cell sorting and large-scale expansion of single KIR-positive alloreactive human natural killer cells for multiple infusions to leukemia patients. Cytotherapy 2010; 12: 750-763
    • (2010) Cytotherapy , vol.12 , pp. 750-763
    • Siegler, U.1    Meyer-Monard, S.2    Jorger, S.3    Stern, M.4    Tichelli, A.5    Gratwohl, A.6
  • 75
    • 84885723035 scopus 로고    scopus 로고
    • Antigen presenting cell-mediated expansion of human umbilical cord blood yields logscale expansion of natural killer cells with anti-myeloma activity
    • Shah N, Martin-Antonio B, Yang H, Ku S, Lee DA, Cooper LJ, et al. Antigen presenting cell-mediated expansion of human umbilical cord blood yields logscale expansion of natural killer cells with anti-myeloma activity. PLoS One 2013; 8: e76781
    • (2013) Plos One , vol.8 , pp. e76781
    • Shah, N.1    Martin-Antonio, B.2    Yang, H.3    Ku, S.4    Lee, D.A.5    Cooper, L.J.6
  • 77
    • 79952304769 scopus 로고    scopus 로고
    • Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with ny-eso-1
    • Robbins PF, Morgan RA, Feldman SA, Yang JC, Sherry RM, Dudley ME, et al. Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1. J Clin Oncol 2011; 29: 917-924
    • (2011) J Clin Oncol , vol.29 , pp. 917-924
    • Robbins, P.F.1    Morgan, R.A.2    Feldman, S.A.3    Yang, J.C.4    Sherry, R.M.5    Dudley, M.E.6
  • 78
    • 84880857272 scopus 로고    scopus 로고
    • Prolonged t cell persistence, homing to marrow and selective targeting of antigen positive tumor in multiple myeloma patients following adoptive transfer of t cells genetically engineered to express an affinity-enhanced t cell receptor against the cancer testis antigens ny-eso-1 and lage-1
    • ASH Annual Meeting Abstracts
    • Kalos M, Rapoport AP, Stadtmauer EA, Vogl DT, Weiss BM, Binder-Scholl GK, et al. Prolonged T cell persistence, homing to marrow and selective targeting of antigen positive tumor in multiple myeloma patients following adoptive transfer of T cells genetically engineered to express an affinity-enhanced T cell receptor against the cancer testis antigens NY-ESO-1 and Lage-1. Blood 2012; 120: 755 (ASH Annual Meeting Abstracts
    • (2012) Blood , vol.120 , pp. 755
    • Kalos, M.1    Rapoport, A.P.2    Stadtmauer, E.A.3    Vogl, D.T.4    Weiss, B.M.5    Binder-Scholl, G.K.6
  • 79
    • 84881186036 scopus 로고    scopus 로고
    • Adoptive transfer of gene-modified t-cells engineered to express highaffinity tcrs for cancer-testis antigens (ctas) ny-eso-1 or lage-1, in mm patients post auto-sct
    • ASH Annual Meeting Abstracts
    • Rapoport AP, Stadtmauer EA, Vogl DT, Weiss BM, Binder-Scholl GK, Brewer JE, et al. Adoptive transfer of gene-modified T-cells engineered to express highaffinity TCRs for cancer-testis antigens (CTAs) NY-ESO-1 or Lage-1, in MM patients post auto-SCT. Blood 2012; 120: 472 (ASH Annual Meeting Abstracts
    • (2012) Blood , vol.120 , pp. 472
    • Rapoport, A.P.1    Stadtmauer, E.A.2    Vogl, D.T.3    Weiss, B.M.4    Binder-Scholl, G.K.5    Brewer, J.E.6
  • 80
    • 84880730689 scopus 로고    scopus 로고
    • Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma
    • Linette GP, Stadtmauer EA, Maus MV, Rapoport AP, Levine BL, Emery L, et al. Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma. Blood 2013; 122: 863-871
    • (2013) Blood , vol.122 , pp. 863-871
    • Linette, G.P.1    Stadtmauer, E.A.2    Maus, M.V.3    Rapoport, A.P.4    Levine, B.L.5    Emery, L.6
  • 82
    • 84896335556 scopus 로고    scopus 로고
    • Efficacy and toxicity management of 19-28z car t cell therapy in b cell acute lymphoblastic leukemia
    • 224ra25
    • Davila ML, Riviere I, Wang X, Bartido S, Park J, Curran K, et al. Efficacy and toxicity management of 19-28z CAR T cell therapy in B cell acute lymphoblastic leukemia. Sci Transl Med 2014; 6: 224ra25
    • (2014) Sci Transl Med , vol.6
    • Davila, M.L.1    Riviere, I.2    Wang, X.3    Bartido, S.4    Park, J.5    Curran, K.6
  • 83
    • 80051720194 scopus 로고    scopus 로고
    • Chimeric antigen receptormodified T cells in chronic lymphoid leukemia
    • Porter DL, Levine BL, Kalos M, Bagg A, June CH. Chimeric antigen receptormodified T cells in chronic lymphoid leukemia. N Engl J Med 2011; 365: 725-733
    • (2011) N Engl J Med , vol.365 , pp. 725-733
    • Porter, D.L.1    Levine, B.L.2    Kalos, M.3    Bagg, A.4    June, C.H.5
  • 84
    • 84907293786 scopus 로고    scopus 로고
    • Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor
    • e-pub ahead of print 25 August JCO.2014.56.2025 JCO.2014.56.2025
    • Kochenderfer JN, Dudley ME, Kassim SH, Somerville RP, Carpenter RO, Stetler-Stevenson M, et al. Chemotherapy-refractory diffuse large B-cell lymphoma and indolent B-cell malignancies can be effectively treated with autologous T cells expressing an anti-CD19 chimeric antigen receptor. J Clin Oncol. (e-pub ahead of print 25 August 2014; doi: JCO.2014.56.2025
    • (2014) J Clin Oncol
    • Kochenderfer, J.N.1    Dudley, M.E.2    Kassim, S.H.3    Somerville, R.P.4    Carpenter, R.O.5    Stetler-Stevenson, M.6
  • 86
    • 84894325649 scopus 로고    scopus 로고
    • Transfection of chimeric anti-CD138 gene enhances natural killer cell activation and killing of multiple myeloma cells
    • Jiang H, Zhang W, Shang P, Zhang H, Fu W, Ye F, et al. Transfection of chimeric anti-CD138 gene enhances natural killer cell activation and killing of multiple myeloma cells. Mol Oncol 2014; 8: 297-310
    • (2014) Mol Oncol , vol.8 , pp. 297-310
    • Jiang, H.1    Zhang, W.2    Shang, P.3    Zhang, H.4    Fu, W.5    Ye, F.6
  • 87
    • 84856760798 scopus 로고    scopus 로고
    • T-cell immunotherapy with a chimeric receptor against CD38 is effective in eliminating myeloma cells
    • Mihara K, Bhattacharyya J, Kitanaka A, Yanagihara K, Kubo T, Takei Y, et al. T-cell immunotherapy with a chimeric receptor against CD38 is effective in eliminating myeloma cells. Leukemia 2012; 26: 365-367
    • (2012) Leukemia , vol.26 , pp. 365-367
    • Mihara, K.1    Bhattacharyya, J.2    Kitanaka, A.3    Yanagihara, K.4    Kubo, T.5    Takei, Y.6
  • 88
    • 33845256434 scopus 로고    scopus 로고
    • T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells
    • Vera J, Savoldo B, Vigouroux S, Biagi E, Pule M, Rossig C, et al. T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells. Blood 2006; 108: 3890-3897
    • (2006) Blood , vol.108 , pp. 3890-3897
    • Vera, J.1    Savoldo, B.2    Vigouroux, S.3    Biagi, E.4    Pule, M.5    Rossig, C.6
  • 89
    • 84888270638 scopus 로고    scopus 로고
    • CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma
    • Casucci M, Nicolis di Robilant B, Falcone L, Camisa B, Norelli M, Genovese P, et al. CD44v6-targeted T cells mediate potent antitumor effects against acute myeloid leukemia and multiple myeloma. Blood 2013; 122: 3461-3472
    • (2013) Blood , vol.122 , pp. 3461-3472
    • Casucci, M.1    Nicolis Di Robilant, B.2    Falcone, L.3    Camisa, B.4    Norelli, M.5    Genovese, P.6
  • 90
    • 77952420345 scopus 로고    scopus 로고
    • Gene-modified T cells as immunotherapy for multiple myeloma and acute myeloid leukemia expressing the Lewis y antigen
    • Peinert S, Prince HM, Guru PM, Kershaw MH, Smyth MJ, Trapani JA, et al. Gene-modified T cells as immunotherapy for multiple myeloma and acute myeloid leukemia expressing the Lewis Y antigen. Gene Ther 2010; 17: 678-686
    • (2010) Gene Ther , vol.17 , pp. 678-686
    • Peinert, S.1    Prince, H.M.2    Guru, P.M.3    Kershaw, M.H.4    Smyth, M.J.5    Trapani, J.A.6
  • 91
    • 84898461706 scopus 로고    scopus 로고
    • CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma
    • Chu J, Deng Y, Benson DM, He S, Hughes T, Zhang J, et al. CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma. Leukemia 2014; 28: 917-927
    • (2014) Leukemia , vol.28 , pp. 917-927
    • Chu, J.1    Deng, Y.2    Benson, D.M.3    He, S.4    Hughes, T.5    Zhang, J.6
  • 93
    • 0942298590 scopus 로고    scopus 로고
    • Expression of bcma, taci, and baff-r in multiple myeloma: A mechanism for growth and survival
    • Novak AJ, Darce JR, Arendt BK, Harder B, Henderson K, Kindsvogel W, et al. Expression of BCMA, TACI, and BAFF-R in multiple myeloma: a mechanism for growth and survival. Blood 2004; 103: 689-694
    • (2004) Blood , vol.103 , pp. 689-694
    • Novak, A.J.1    Darce, J.R.2    Arendt, B.K.3    Harder, B.4    Henderson, K.5    Kindsvogel, W.6
  • 94
    • 11144355586 scopus 로고    scopus 로고
    • Baff and april protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone
    • Moreaux J, Legouffe E, Jourdan E, Quittet P, Reme T, Lugagne C, et al. BAFF and APRIL protect myeloma cells from apoptosis induced by interleukin 6 deprivation and dexamethasone. Blood 2004; 103: 3148-3157
    • (2004) Blood , vol.103 , pp. 3148-3157
    • Moreaux, J.1    Legouffe, E.2    Jourdan, E.3    Quittet, P.4    Reme, T.5    Lugagne, C.6
  • 95
    • 20844450993 scopus 로고    scopus 로고
    • Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to bcma, a plasma-cell membrane receptor
    • Bellucci R, Alyea EP, Chiaretti S, Wu CJ, Zorn E, Weller E, et al. Graft-versus-tumor response in patients with multiple myeloma is associated with antibody response to BCMA, a plasma-cell membrane receptor. Blood 2005; 105: 3945-3950
    • (2005) Blood , vol.105 , pp. 3945-3950
    • Bellucci, R.1    Alyea, E.P.2    Chiaretti, S.3    Wu, C.J.4    Zorn, E.5    Weller, E.6
  • 96
    • 35348915408 scopus 로고    scopus 로고
    • Neutralizing B-cell activating factor antibody improves survival and inhibits osteoclastogenesis in a severe combined immunodeficient human multiple myeloma model
    • Neri P, Kumar S, Fulciniti MT, Vallet S, Chhetri S, Mukherjee S, et al. Neutralizing B-cell activating factor antibody improves survival and inhibits osteoclastogenesis in a severe combined immunodeficient human multiple myeloma model. Clin Cancer Res 2007; 13: 5903-5909
    • (2007) Clin Cancer Res , vol.13 , pp. 5903-5909
    • Neri, P.1    Kumar, S.2    Fulciniti, M.T.3    Vallet, S.4    Chhetri, S.5    Mukherjee, S.6
  • 97
    • 84877087137 scopus 로고    scopus 로고
    • B-cell maturation antigen is a promising target for adoptive T-cell therapy of multiple myeloma
    • Carpenter RO, Evbuomwan MO, Pittaluga S, Rose JJ, Raffeld M, Yang S, et al. B-cell maturation antigen is a promising target for adoptive T-cell therapy of multiple myeloma. Clin Cancer Res 2013; 19: 2048-2060
    • (2013) Clin Cancer Res , vol.19 , pp. 2048-2060
    • Carpenter, R.O.1    Evbuomwan, M.O.2    Pittaluga, S.3    Rose, J.J.4    Raffeld, M.5    Yang, S.6
  • 98
    • 84901433313 scopus 로고    scopus 로고
    • Novel anti-b-cell maturation antigen antibody-drug conjugate (gsk2857916) selectively induces killing of multiple myeloma
    • Tai YT, Mayes PA, Acharya C, Zhong MY, Cea M, Cagnetta A, et al. Novel anti-B-cell maturation antigen antibody-drug conjugate (GSK2857916) selectively induces killing of multiple myeloma. Blood 2014; 123: 3128-3138
    • (2014) Blood , vol.123 , pp. 3128-3138
    • Tai, Y.T.1    Mayes, P.A.2    Acharya, C.3    Zhong, M.Y.4    Cea, M.5    Cagnetta, A.6
  • 100
    • 0028908877 scopus 로고
    • In multiple myeloma, clonotypic b lymphocytes are detectable among cd19+ peripheral blood cells expressing cd38, cd56, and monotypic ig light chain
    • Bergsagel PL, Smith AM, Szczepek A, Mant MJ, Belch AR, Pilarski LM. In multiple myeloma, clonotypic B lymphocytes are detectable among CD19+ peripheral blood cells expressing CD38, CD56, and monotypic Ig light chain. Blood 1995; 85: 436-447
    • (1995) Blood , vol.85 , pp. 436-447
    • Bergsagel, P.L.1    Smith, A.M.2    Szczepek, A.3    Mant, M.J.4    Belch, A.R.5    Pilarski, L.M.6
  • 102
    • 38549132452 scopus 로고    scopus 로고
    • Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance
    • Matsui W, Wang Q, Barber JP, Brennan S, Smith BD, Borrello I, et al. Clonogenic multiple myeloma progenitors, stem cell properties, and drug resistance. Cancer Res 2008; 68: 190-197
    • (2008) Cancer Res , vol.68 , pp. 190-197
    • Matsui, W.1    Wang, Q.2    Barber, J.P.3    Brennan, S.4    Smith, B.D.5    Borrello, I.6
  • 103
    • 84883625365 scopus 로고    scopus 로고
    • Xbp1s-negative tumor B cells and pre-plasmablasts mediate therapeutic proteasome inhibitor resistance in multiple myeloma
    • Leung-Hagesteijn C, Erdmann N, Cheung G, Keats JJ, Stewart AK, Reece DE, et al. Xbp1s-negative tumor B cells and pre-plasmablasts mediate therapeutic proteasome inhibitor resistance in multiple myeloma. Cancer Cell 2013; 24: 289-304
    • (2013) Cancer Cell , vol.24 , pp. 289-304
    • Leung-Hagesteijn, C.1    Erdmann, N.2    Cheung, G.3    Keats, J.J.4    Stewart, A.K.5    Reece, D.E.6
  • 107
    • 31344466491 scopus 로고    scopus 로고
    • Autologous tumor combined with a gm-csf-secreting cell line vaccine (gvax(r)) following autologous stem cell transplant (asct) in multiple myeloma
    • Borrello I, Biedrzycki B, Sheets N, George B, Racke F, Loper K, et al. Autologous tumor combined with a GM-CSF-secreting cell line vaccine (GVAX(R)) following autologous stem cell transplant (ASCT) in multiple myeloma. ASH Annual Meeting Abstracts 2004; 104: 440
    • (2004) ASH Annual Meeting Abstracts , vol.104 , pp. 440
    • Borrello, I.1    Biedrzycki, B.2    Sheets, N.3    George, B.4    Racke, F.5    Loper, K.6
  • 108
    • 0033566327 scopus 로고    scopus 로고
    • Idiotype vaccination in human myeloma: Generation of tumor-specific immune responses after high-dose chemotherapy
    • Massaia M, Borrione P, Battaglio S, Mariani S, Beggiato E, Napoli P, et al. Idiotype vaccination in human myeloma: generation of tumor-specific immune responses after high-dose chemotherapy. Blood 1999; 94: 673-683
    • (1999) Blood , vol.94 , pp. 673-683
    • Massaia, M.1    Borrione, P.2    Battaglio, S.3    Mariani, S.4    Beggiato, E.5    Napoli, P.6


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