Determinants of serum 25(OH)D concentration in young and middle-aged adults. The Cardiovascular Risk in Young Finns Study

Annals of Medicine

Volumn 47, Issue 3, 2015, Pages 253-262

  Voipio, Atte J W ^a   Pahkala, Katja A ^a,b   Viikari, Jorma S A ^c   Mikkilä, Vera ^a,d   Magnussen, Costan G ^a,e   Hutri Kähönen, Nina ^f   Kähönen, Mika ^f,g   Lehtimäki, Terho ^f,h   Männistö, Satu ⁱ   Loo, Britt Marie ⁱ   Jula, Antti ⁱ   Marniemi, Jukka ⁱ   Juonala, Markus ^a,c   Raitakari, Olli T ^a,c  

^a UNIVERSITY OF TURKU   (Finland)

^b Paavo Nurmi Centre   (Finland)

^c TURKU UNIVERSITY HOSPITAL   (Finland)

^d UNIVERSITY OF HELSINKI   (Finland)

^e UNIVERSITY OF TASMANIA   (Australia)

^f TAMPERE UNIVERSITY OF TECHNOLOGY   (Finland)

^g TAMPERE UNIVERSITY HOSPITAL   (Finland)

^h FIMLAB LABORATORIES   (Finland)

ⁱ NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

25(OH)D; Fortification; Hypovitaminosis D; Single nucleotide polymorphism; Vitamin D; Young Finns Study

Indexed keywords

25 HYDROXYVITAMIN D; 25-HYDROXYVITAMIN D; ORAL CONTRACEPTIVE AGENT; VITAMIN D;

ADULT; ALCOHOL CONSUMPTION; ALLELE; ARTICLE; BLOOD SAMPLING; BODY MASS; CARDIOVASCULAR RISK; DIETARY INTAKE; FEMALE; GENETIC RISK; GENOTYPE; HUMAN; MALE; MIDDLE AGED; ORAL CONTRACEPTIVE USE; PREVALENCE; PRIORITY JOURNAL; RISK ASSESSMENT; SINGLE NUCLEOTIDE POLYMORPHISM; SMOKING; SUN EXPOSURE; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY; VITAMIN INTAKE; YOUNG ADULT; ANALOGS AND DERIVATIVES; BLOOD; CARDIOVASCULAR DISEASES; CROSS-SECTIONAL STUDY; DIET; DIETARY SUPPLEMENT; FINLAND; GENETICS; PATHOLOGY; RISK FACTOR; SEASON;

ADULT; ALLELES; CARDIOVASCULAR DISEASES; CONTRACEPTIVES, ORAL; CROSS-SECTIONAL STUDIES; DIET; DIETARY SUPPLEMENTS; FEMALE; FINLAND; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PREVALENCE; RISK FACTORS; SEASONS; VITAMIN D; VITAMIN D DEFICIENCY;

EID: 84930329797     PISSN: 07853890     EISSN: 13652060     Source Type: Journal    
DOI: 10.3109/07853890.2015.1020860     Document Type: Article

References (64)

1. McCollum EV, Simmonds N, Becker JE, Shipley PG. Studies on experimental rickets. Journal of Biological Chemistry. 1922; 53: 293-312.
2. Huldschinsky K. Heilung von Rachitis durch Kün stliche Höh ensonne (German: Healing from rickets with the aid of artificial sunlight). Dtsch Med Wochenschr. 1919; 45: 90-1.
3. Mozolowski W. Jedrezj Sniadecki (1768-1838) on the Cure of Rickets. Nature. 1939; 143: 121.
4. Scragg R, Sowers M, Bell C; Third National Health and Nutrition Examination Survey. Serum 25-hydroxyvitamin D, diabetes, and ethnicity in the Third National Health and Nutrition Examination Survey. Diabetes Care. 2004; 27: 2813-18.
5. Hyppönen E, Laara E, Reunanen A, Järvelin MR, Virtanen SM. Intake of vitamin D and risk of type 1 diabetes: a birth-cohort study. Lancet. 2001; 358: 1500-3.
6. Zittermann A, Schleithoff SS, Tenderich G, Berthold HK, Korfer R, Stehle P. Low vitamin D status: a contributing factor in the pathogenesis of congestive heart failure? J Am Coll Cardiol. 2003; 41: 105-12.
7. Kendrick J, Targher G, Smits G, Chonchol M. 25-Hydroxyvitamin D deficiency is independently associated with cardiovascular disease in the Th ird National Health and Nutrition Examination Survey. Atherosclerosis. 2009; 205: 255-60.
8. Marniemi J, Alanen E, Impivaara O, Seppänen R, Hakala P, Rajala T, et al. Dietary and serum vitamins and minerals as predictors of myocardial infarction and stroke in elderly subjects. Nutr Metab Cardiovasc Dis. 2005; 15: 188-97.
9. Kilkkinen A, Knekt P, Aro A, Rissanen H, Marniemi J, Heliövaara M, et al. Vitamin D status and the risk of cardiovascular disease death. Am J Epidemiol. 2009; 170: 1032-9.
10. Garland CF, Garland FC, Gorham ED. Calcium and vitamin D. Their potential roles in colon and breast cancer prevention. Ann NY Acad Sci. 1999; 889: 107-19.
11. Looker AC, Pfeiffer CM, Lacher DA, Schleicher RL, Picciano MF, Yetley EA. Serum 25-hydroxyvitamin D status of the US population: 1988-1994 compared with 2000-2004. Am J Clin Nutr. 2008;88: 1519-27.
12. Lips P. Vitamin D status and nutrition in Europe and Asia. J Steroid Biochem Mol Biol. 2007; 103: 620-5.
13. Duplessis CA, Harris EB, Watenpaugh DE, Horn WG. Vitamin D supplementation in underway submariners. Aviat Space Environ Med. 2005; 76: 569-75.
14. Ross AC, Taylor CL, Yaktine AL, Del Valle HB. IOM (Institute of Medicine). 2011. Committee to Review Dietary Reference Intakes for Vitamin D and Calcium. 2011.
15. Helldán A, Raulio S, Kosola M, Tapanainen H, Ovaskainen M, Virtanen S. Finravinto 2012-tutkimus/The National FINDIET 2012 Survey. 2012;16/2013 Juvenes Print-Suomen Yliopistopaino Oy, Tampere, Finland. Permanent link: http://urn.fi/URN:ISBN:978-952-245-951-0..
16. Holick MF, MacLaughlin JA, Clark MB, Holick SA, Potts JT Jr, Anderson RR, et al. Photosynthesis of previtamin D3 in human skin and the physiologic consequences. Science. 1980; 210: 203-5.
17. de Gruijl FR. Sufficient vitamin D from casual sun exposure? Photochem Photobiol. 2011; 87: 598-601.
18. Kamycheva E, Joakimsen RM, Jorde R. Intakes of calcium and vitamin d predict body mass index in the population of Northern Norway. J Nutr. 2003; 133: 102-6.
19. Lamberg-Allardt CJ, Outila TA, Kärkkäinen MU, Rita HJ, Valsta LM. Vitamin D deficiency and bone health in healthy adults in Finland: could this be a concern in other parts of Europe? J Bone Miner Res. 2001; 16: 2066-73.
20. Sowers MR, Wallace RB, Hollis BW, Lemke JH. Parameters related to 25-OH-D levels in a population-based study of women. Am J Clin Nutr. 1986; 43: 621-8.
21. Wang TJ, Zhang F, Richards JB, Kestenbaum B, van Meurs JB, Berry D, et al. Common genetic determinants of vitamin D insufficiency: a genome-wide association study. Lancet. 2010; 376: 180-8.
22. Åkerblom HK, Viikari J, Uhari M, Räsänen L, Byckling T, Louhivuori K, et al. Atherosclerosis precursors in Finnish children and adolescents. I. General description of the cross-sectional study of 1980, and an account of the children's and families'state of health. Acta Paediatr Scand Suppl. 1985; 318: 49-63.
23. Kauppinen-Mäkelin R, Tähtelä R, Löyttyniemi E, Kärkkäinen J, Välimäki MJ. A high prevalence of hypovitaminosis D in Finnish medical in-and outpatients. J Intern Med. 2001; 249: 559-63.
24. Männistö S, Virtanen M, Mikkonen T, Pietinen P. Reproducibility and validity of a food frequency questionnaire in a case-control study on breast cancer. J Clin Epidemiol. 1996; 49: 401-9.
25. National Public Health Institute of Finland. Fineli. Finnish Food Composition Database. Release 7. Helsinki, Finland, the National Public Health Institute, Nutrition Unit, 2007. Available at: http://www. fineli.fi/.
26. Nordic Council of Ministers. Nordic Nutrition Recommendations 2012. Part 1. NNR 5 2013 Oct 03, 2013;Nord 2013:009.
27. Nordic Council of Ministers. Nordic nutrition recommendations 2004. Integrating nutrition and physical activity. Århus, Denmark: Nordic Council of Ministers; 2004.
28. Juonala M, Viikari JS, Hutri-Kähönen N, Pietikäinen M, Jokinen E, Taittonen L, et al. The 21-year follow-up of the Cardiovascular Risk in Young Finns Study: risk factor levels, secular trends and east-west difference. J Intern Med. 2004; 255: 457-68.
29. Firtser S, Juonala M, Magnussen CG, Jula A, Loo BM, Marniemi J, et al. Relation of total and free testosterone and sex hormone-binding globulin with cardiovascular risk factors in men aged 24-45 years. The Cardiovascular Risk in Young Finns Study. Atherosclerosis. 2012; 222: 257-62.
30. Mansikkaniemi K, Juonala M, Taimela S, Hirvensalo M, Telama R, Huupponen R, et al. Cross-sectional associations between physical activity and selected coronary heart disease risk factors in young adults. The Cardiovascular Risk in Young Finns Study. Ann Med. 2012; 44: 733-44.
31. Vimaleswaran KS, Berry DJ, Lu C, Tikkanen E, Pilz S, Hiraki LT, et al. Causal relationship between obesity and vitamin D status: bi-directional Mendelian randomization analysis of multiple cohorts. PLoS Med. 2013; 10: e1001383.
32. Paturi M, Tapanainen H, Reinivuo H, Pietinen P. The National FINDIET 2007 Survey. 2008;23.
33. Whiting SJ, Green TJ, Calvo MS. Vitamin D intakes in North America and Asia-Pacific countries are not sufficient to prevent vitamin D insufficiency. J Steroid Biochem Mol Biol. 2007; 103: 626-30.
34. Hirvonen T, Sinkko H, Valsta L, Hannila ML, Pietinen P. Development of a model for optimal food fortification: vitamin D among adults in Finland. Eur J Nutr. 2007; 46: 264-70.
35. Aarskog D, Aksnes L, Markestad T, Rodland O. Effect of estrogen on vitamin D metabolism in tall girls. J Clin Endocrinol Metab. 1983; 57: 1155-8.
36. Harris SS, Dawson-Hughes B. The association of oral contraceptive use with plasma 25-hydroxyvitamin D levels. J Am Coll Nutr. 1998; 17: 282-4.
37. Nesby-O'Dell S, Scanlon KS, Cogswell ME, Gillespie C, Hollis BW, Looker AC, et al. Hypovitaminosis D prevalence and determinants among African American and white women of reproductive age: third National Health and Nutrition Examination Survey, 1988-1994. Am J Clin Nutr. 2002; 76: 187-92.
38. Holick MF. Vitamin D deficiency. N Engl J Med. 2007; 357: 266-81.
39. Drincic AT, Armas LA, Van Diest EE, Heaney RP. Volumetric dilution, rather than sequestration best explains the low vitamin D status of obesity. Obesity (Silver Spring). 2012; 20: 1444-8.
40. Välimäki VV, Löyttyniemi E, Välimäki MJ. Vitamin D fortification of milk products does not resolve hypovitaminosis D in young Finnish men. Eur J Clin Nutr. 2007; 61: 493-7.
41. Brustad M, Alsaker E, Engelsen O, Aksnes L, Lund E. Vitamin D status of middle-aged women at 65-71 degrees N in relation to dietary intake and exposure to ultraviolet radiation. Public Health Nutr. 2004; 7: 327-35.
42. Lorentzon M, Mellstrom D, Haug E, Ohlsson C. Smoking is associated with lower bone mineral density and reduced cortical thickness in young men. J Clin Endocrinol Metab. 2007; 92: 497-503.
43. Snijder MB, Lips P, Seidell JC, Visser M, Deeg DJ, Dekker JM, et al. Vitamin D status and parathyroid hormone levels in relation to blood pressure: a population-based study in older men and women. J Intern Med. 2007; 261: 558-65.
44. McKinney K, Breitkopf CR, Berenson AB. Association of race, body fat and season with vitamin D status among young women: a crosssectional study. Clin Endocrinol (Oxf). 2008; 69: 535-41.
45. Naude CE, Carey PD, Laubscher R, Fein G, Senekal M. Vitamin D and calcium status in South African adolescents with alcohol use disorders. Nutrients. 2012; 4: 1076-94.
46. Ilich JZ, Brownbill RA, Tamborini L, Crncevic-Orlic Z. To drink or not to drink: how are alcohol, caffeine and past smoking related to bone mineral density in elderly women? J Am Coll Nutr. 2002; 21: 536-44.
47. Hirani V, Cumming RG, Blyth FM, Naganathan V, Le Couteur DG, Handelsman DJ, et al. Vitamin D status among older community dwelling men living in a sunny country and associations with lifestyle factors: the Concord Health and Ageing in Men Project, Sydney, Australia. J Nutr Health Aging. 2013; 17: 587-93.
48. Hollander D, Muralidhara KS, Zimmerman A. Vitamin D-3 intestinal absorption in vivo: influence of fatty acids, bile salts, and perfusate pH on absorption. Gut. 1978; 19: 267-72.
49. Reboul E, Goncalves A, Comera C, Bott R, Nowicki M, Landrier JF, et al. Vitamin D intestinal absorption is not a simple passive diff usion: evidences for involvement of cholesterol transporters. Mol Nutr Food Res. 2011; 55: 691-702.
50. Haddad JG, Matsuoka LY, Hollis BW, Hu YZ, Wortsman J. Human plasma transport of vitamin D after its endogenous synthesis. J Clin Invest. 1993; 91: 2552-5.
51. Lund J, DeLuca HF. Biologically active metabolite of vitamin D3 from bone, liver, and blood serum. J Lipid Res. 1966; 7: 739-44.
52. Shinkyo R, Sakaki T, Kamakura M, Ohta M, Inouye K. Metabolism of vitamin D by human microsomal CYP2R1. Biochem Biophys Res Commun. 2004; 324: 451-7.
53. Masuda S, Byford V, Arabian A, Sakai Y, Demay MB, St-Arnaud R, et al. Altered pharmacokinetics of 1a,25-dihydroxyvitamin D3 and 25-hydroxyvitamin D3 in the blood and tissues of the 25-hydroxyvitamin D-24-hydroxylase (Cyp24a1) null mouse. Endocrinology. 2005; 146: 825-34.
54. Millen AE, Wactawski-Wende J, Pettinger M, Melamed ML, Tylavsky FA, Liu S, et al. Predictors of serum 25-hydroxyvitamin D concentrations among postmenopausal women: the Women's Health Initiative Calcium plus Vitamin D clinical trial. Am J Clin Nutr. 2010; 91: 1324-35.
55. Bertrand KA, Giovannucci E, Liu Y, Malspeis S, Eliassen AH, Wu K, et al. Determinants of plasma 25-hydroxyvitamin D and development of prediction models in three US cohorts. Br J Nutr. 2012; 108: 1889-96.
56. Freedman DM, Cahoon EK, Rajaraman P, Major JM, Doody MM, Alexander BH, et al. Sunlight and other determinants of circulating 25-hydroxyvitamin D levels in black and white participants in a nationwide U.S. study. Am J Epidemiol. 2013; 177: 180-92.
57. Kuhn T, Kaaks R, Teucher B, Hirche F, Dierkes J, Weikert C, et al. Dietary, lifestyle, and genetic determinants of vitamin D status: a cross-sectional analysis from the European Prospective Investigation into Cancer and Nutrition (EPIC)-Germany study. Eur J Nutr. 2014; 53: 731-41.
58. Veugelers PJ, Ekwaru JP. A statistical error in the estimation of the recommended dietary allowance for vitamin D. Nutrients. 2014; 6: 4472-5.
59. Greene-Finestone LS, Berger C, de Groh M, Hanley DA, Hidiroglou N, Sarafin K, et al. 25-Hydroxyvitamin D in Canadian adults: biological, environmental, and behavioral correlates. Osteoporos Int. 2011; 22: 1389-99.
60. Basha B, Rao DS, Han ZH, Parfitt AM. Osteomalacia due to vitamin D depletion: a neglected consequence of intestinal malabsorption. Am J Med. 2000; 108: 296-300.
61. Bischoff-Ferrari HA, Willett WC, Wong JB, Giovannucci E, Dietrich T, Dawson-Hughes B. Fracture prevention with vitamin D supplementation: a meta-analysis of randomized controlled trials. JAMA. 2005; 293: 2257-64.
62. Th omas MK, Lloyd-Jones DM, Th adhani RI, Shaw AC, Deraska DJ, Kitch BT, et al. Hypovitaminosis D in medical inpatients. N Engl J Med. 1998; 338: 777-83.
63. Kinyamu HK, Gallagher JC, Rafferty KA, Balhorn KE. Dietary calcium and vitamin D intake in elderly women: effect on serum parathyroid hormone and vitamin D metabolites. Am J Clin Nutr. 1998; 67: 342-8.
64. Adams JS, Hewison M. Update in vitamin D. J Clin Endocrinol Metab. 2010; 95: 471-8.