X-ray and cryo-electron microscopy structures of Monalysin pore-forming toxin reveal multimerization of the pro-form

Journal of Biological Chemistry

Volumn 290, Issue 21, 2015, Pages 13191-13201

  Leone, Philippe ^a,b   Bebeacua, Cecilia ^a,b   Opota, Onya ^e   Kellenberger, Christine ^a,b   Klaholz, Bruno ^d   Orlov, Igor ^d   Cambillau, Christian ^a,b   Lemaitre, Bruno ^c   Roussel, Alain ^a,b  

^a Centre National de la Recherche Scientifique   (France)

^b AIX MARSEILLE UNIVERSITY   (France)

^c EPFL   (Switzerland)

^d INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^e LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CELL MEMBRANES; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; ELECTRON MICROSCOPES; ELECTRON MICROSCOPY; LIGHT SCATTERING; METABOLITES; OLIGOMERS; PEPTIDES; TOXIC MATERIALS;

CELL SURFACE RECEPTORS; CRYO-ELECTRON MICROSCOPY; MEMBRANE INTERACTIONS; MEMBRANE SPANNING REGIONS; PROTEOLYTIC CLEAVAGE; RECEPTOR-BINDING DOMAINS; TRANSMEMBRANE SEGMENTS; WATER SOLUBLE MONOMERS;

X RAY CRYSTALLOGRAPHY;

AEROLYSIN; BACTERIAL TOXIN; MONALYSIN; UNCLASSIFIED DRUG; PORE FORMING CYTOTOXIC PROTEIN; PROTEIN BINDING;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL SURFACE; CHANNEL GATING; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; CRYSTAL STRUCTURE; LIGHT SCATTERING; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CLEAVAGE; PROTEIN MULTIMERIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TRANSPORT; RECEPTOR BINDING; X RAY CRYSTALLOGRAPHY; AMINO ACID SEQUENCE; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; CRYSTALLIZATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR GENETICS; MUTATION; PROCEDURES; PROTEIN TERTIARY STRUCTURE; PSEUDOMONAS; SEQUENCE HOMOLOGY;

BACTERIA (MICROORGANISMS); PSEUDOMONAS ENTOMOPHILA;

AMINO ACID SEQUENCE; BACTERIAL TOXINS; CELL MEMBRANE; CRYOELECTRON MICROSCOPY; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PORE FORMING CYTOTOXIC PROTEINS; PROTEIN BINDING; PROTEIN MULTIMERIZATION; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84930227238     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.646109     Document Type: Article

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