-
1
-
-
0001284038
-
-
JCPSA6 0021-9606 10.1063/1.459195
-
T.A.J. Duke, J. Chem. Phys. 93, 9049 (1990). JCPSA6 0021-9606 10.1063/1.459195
-
(1990)
J. Chem. Phys.
, vol.93
, pp. 9049
-
-
Duke, T.A.J.1
-
2
-
-
0035894044
-
-
ANCHAM 0003-2700 10.1021/ac015527o
-
O. Bakajin, T.A.J. Duke, J. Tegenfeldt, C.-F. Chou, S.S. Chan, R.H. Austin, and E.C. Cox, Anal. Chem. 73, 6053 (2001). ANCHAM 0003-2700 10.1021/ac015527o
-
(2001)
Anal. Chem.
, vol.73
, pp. 6053
-
-
Bakajin, O.1
Duke, T.A.J.2
Tegenfeldt, J.3
Chou, C.-F.4
Chan, S.S.5
Austin, R.H.6
Cox, E.C.7
-
3
-
-
0036788449
-
-
NABIF9 1087-0156 10.1038/nbt733
-
L.R. Huang, J.O. Tegenfeldt, J.J. Kraeft, J.C. Sturm, R.H. Austin, and E.C. Cox, Nat. Biotechnol. 20, 1048 (2002). NABIF9 1087-0156 10.1038/nbt733
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 1048
-
-
Huang, L.R.1
Tegenfeldt, J.O.2
Kraeft, J.J.3
Sturm, J.C.4
Austin, R.H.5
Cox, E.C.6
-
4
-
-
4043068454
-
-
PNASA6 0027-8424 10.1073/pnas.0403849101
-
J.O. Tegenfeldt, C. Prinz, H. Cao, S. Chou, W.W. Reisner, R. Riehn, Y.M. Wang, E.C. Cox, J.C. Sturm, P. Silberzan, Proc. Natl. Acad. Sci. U.S.A. 101, 10979 (2004). PNASA6 0027-8424 10.1073/pnas.0403849101
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 10979
-
-
Tegenfeldt, J.O.1
Prinz, C.2
Cao, H.3
Chou, S.4
Reisner, W.W.5
Riehn, R.6
Wang, Y.M.7
Cox, E.C.8
Sturm, J.C.9
Silberzan, P.10
-
5
-
-
84864883566
-
-
NABIF9 1087-0156 10.1038/nbt.2303
-
E.T. Lam, A. Hastie, C. Lin, D. Ehrlich, S.K. Das, M.D. Austin, P. Deshpande, H. Cao, N. Nagarajan, M. Xiao, Nat. Biotechnol. 30, 771 (2012). NABIF9 1087-0156 10.1038/nbt.2303
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 771
-
-
Lam, E.T.1
Hastie, A.2
Lin, C.3
Ehrlich, D.4
Das, S.K.5
Austin, M.D.6
Deshpande, P.7
Cao, H.8
Nagarajan, N.9
Xiao, M.10
-
6
-
-
79955691833
-
-
POLNCL 1932-6203 10.1371/journal.pone.0019119
-
E. Borgström, S. Lundin, and J. Lundeberg, PLoS One 6, e19119 (2011). POLNCL 1932-6203 10.1371/journal.pone.0019119
-
(2011)
PLoS One
, vol.6
, pp. e19119
-
-
Borgström, E.1
Lundin, S.2
Lundeberg, J.3
-
7
-
-
0026688439
-
-
NATUAS 0028-0836 10.1038/358600a0
-
W.D. Volkmuth and R.H. Austin, Nature (London) 358, 600 (1992). NATUAS 0028-0836 10.1038/358600a0
-
(1992)
Nature (London)
, vol.358
, pp. 600
-
-
Volkmuth, W.D.1
Austin, R.H.2
-
8
-
-
33749510846
-
-
PNASA6 0027-8424 10.1073/pnas.0605967103
-
J.A. Davis, D.W. Inglis, K.J. Morton, D.A. Lawrence, L.R. Huang, S.Y. Chou, J.C. Sturm, and R.H. Austin, Proc. Natl. Acad. Sci. U.S.A. 103, 14779 (2006). PNASA6 0027-8424 10.1073/pnas.0605967103
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 14779
-
-
Davis, J.A.1
Inglis, D.W.2
Morton, K.J.3
Lawrence, D.A.4
Huang, L.R.5
Chou, S.Y.6
Sturm, J.C.7
Austin, R.H.8
-
9
-
-
33745727445
-
-
LCAHAM 1473-0197 10.1039/b515371a
-
D.W. Inglis, J.A. Davis, R.H. Austin, and J.C. Sturm, Lab Chip 6, 655 (2006). LCAHAM 1473-0197 10.1039/b515371a
-
(2006)
Lab Chip
, vol.6
, pp. 655
-
-
Inglis, D.W.1
Davis, J.A.2
Austin, R.H.3
Sturm, J.C.4
-
10
-
-
36849090529
-
-
JIMMBG 0022-1759 10.1016/j.jim.2007.10.004
-
D.W. Inglis, J.A. Davis, T.J. Zieziulewicz, D.A. Lawrence, R.H. Austin, and J.C. Sturm, J. Immunol. Methods 329, 151 (2008). JIMMBG 0022-1759 10.1016/j.jim.2007.10.004
-
(2008)
J. Immunol. Methods
, vol.329
, pp. 151
-
-
Inglis, D.W.1
Davis, J.A.2
Zieziulewicz, T.J.3
Lawrence, D.A.4
Austin, R.H.5
Sturm, J.C.6
-
11
-
-
60149110663
-
-
PRLTAO 0031-9007 10.1103/PhysRevLett.102.045301
-
K. Loutherback, J. Puchalla, R.H. Austin, and J.C. Sturm, Phys. Rev. Lett. 102, 045301 (2009). PRLTAO 0031-9007 10.1103/PhysRevLett.102.045301
-
(2009)
Phys. Rev. Lett.
, vol.102
, pp. 045301
-
-
Loutherback, K.1
Puchalla, J.2
Austin, R.H.3
Sturm, J.C.4
-
12
-
-
78649722232
-
-
1613-4982 10.1007/s10404-010-0635-y
-
K. Loutherback, K.S. Chou, J. Newman, J. Puchalla, R.H. Austin, and J.C. Sturm, Microfluid. Nanofluid. 9, 1143 (2010). 1613-4982 10.1007/s10404-010-0635-y
-
(2010)
Microfluid. Nanofluid.
, vol.9
, pp. 1143
-
-
Loutherback, K.1
Chou, K.S.2
Newman, J.3
Puchalla, J.4
Austin, R.H.5
Sturm, J.C.6
-
13
-
-
84871877476
-
-
AAIDBI 2158-3226 10.1063/1.4758131
-
K. Loutherback, J. D'Silva, L. Liu, A. Wu, R.H. Austin, and J.C. Sturm, AIP Adv. 2, 042107 (2012). AAIDBI 2158-3226 10.1063/1.4758131
-
(2012)
AIP Adv.
, vol.2
, pp. 042107
-
-
Loutherback, K.1
D'Silva, J.2
Liu, L.3
Wu, A.4
Austin, R.H.5
Sturm, J.C.6
-
14
-
-
2342619619
-
-
SCIEAS 0036-8075 10.1126/science.1094567
-
L.R. Huang, E.C. Cox, R.H. Austin, and J.C. Sturm, Science 304, 987 (2004). SCIEAS 0036-8075 10.1126/science.1094567
-
(2004)
Science
, vol.304
, pp. 987
-
-
Huang, L.R.1
Cox, E.C.2
Austin, R.H.3
Sturm, J.C.4
-
15
-
-
84895449750
-
-
1754-2189 10.1038/nprot.2014.044
-
N.M. Karabacak, Nat. Protoc. 9, 694 (2014). 1754-2189 10.1038/nprot.2014.044
-
(2014)
Nat. Protoc.
, vol.9
, pp. 694
-
-
Karabacak, N.M.1
-
17
-
-
84867042373
-
-
PNASA6 0027-8424 10.1073/pnas.1208689109
-
J. Pelletier, K. Halvorsen, B.-Y. Ha, R. Paparcone, S.J. Sandler, C.L. Woldringh, W.P. Wong, and S. Jun, Proc. Natl. Acad. Sci. U.S.A. 109, E2649 (2012). PNASA6 0027-8424 10.1073/pnas.1208689109
-
(2012)
Proc. Natl. Acad. Sci. U.S.A.
, vol.109
, pp. E2649
-
-
Pelletier, J.1
Halvorsen, K.2
Ha, B.-Y.3
Paparcone, R.4
Sandler, S.J.5
Woldringh, C.L.6
Wong, W.P.7
Jun, S.8
-
19
-
-
0015100570
-
-
PNASA6 0027-8424 10.1073/pnas.68.8.1886
-
L.S. Lerman, Proc. Natl. Acad. Sci. U.S.A. 68, 1886 (1971). PNASA6 0027-8424 10.1073/pnas.68.8.1886
-
(1971)
Proc. Natl. Acad. Sci. U.S.A.
, vol.68
, pp. 1886
-
-
Lerman, L.S.1
-
21
-
-
0000303810
-
-
JPSCAU 0022-3832 10.1002/pol.1958.1203312618
-
S. Asakura and F. Oosawa, J. Polym. Sci. 33, 183 (1958). JPSCAU 0022-3832 10.1002/pol.1958.1203312618
-
(1958)
J. Polym. Sci.
, vol.33
, pp. 183
-
-
Asakura, S.1
Oosawa, F.2
-
23
-
-
36349005211
-
-
LCAHAM 1473-0197 10.1039/b712784g
-
N. Pamme, Lab Chip 7, 1644 (2007). LCAHAM 1473-0197 10.1039/b712784g
-
(2007)
Lab Chip
, vol.7
, pp. 1644
-
-
Pamme, N.1
-
25
-
-
84930237372
-
-
See Supplemental Material at for details on the sample preparation, the parameters of the device, the statistics of bumping, and a description of the movies recorded.
-
See Supplemental Material at http://link.aps.org/supplemental/10.1103/PhysRevLett.114.198303 for details on the sample preparation, the parameters of the device, the statistics of bumping, and a description of the movies recorded.
-
-
-
-
26
-
-
0033548494
-
-
SCIEAS 0036-8075 10.1126/science.283.5408.1724
-
D.E. Smith, H.P. Babcock, and S. Chu, Science 283, 1724 (1999). SCIEAS 0036-8075 10.1126/science.283.5408.1724
-
(1999)
Science
, vol.283
, pp. 1724
-
-
Smith, D.E.1
Babcock, H.P.2
Chu, S.3
-
28
-
-
84930237373
-
-
Staining with one YOYO-1 molecule per 10 base pairs gives a 12% extension of the contour length [29].
-
Staining with one YOYO-1 molecule per 10 base pairs gives a 12% extension of the contour length [29].
-
-
-
-
30
-
-
84999347294
-
-
The thermal blob size of DNA, within which self-avoidance is not felt, is [31] (Equation presented), where (Equation presented) is the excluded volume of a Kuhn segment [see below Eq. (3)]. As (Equation presented) is comparable to the radius of gyration (Equation presented), the freely jointed chain model gives a reasonable approximation for the size of the molecule.
-
The thermal blob size of DNA, within which self-avoidance is not felt, is [31] (Equation presented), where (Equation presented) is the excluded volume of a Kuhn segment [see below Eq. (3)]. As (Equation presented) is comparable to the radius of gyration (Equation presented), the freely jointed chain model gives a reasonable approximation for the size of the molecule.
-
-
-
-
32
-
-
36749109216
-
-
JCPSA6 0021-9606 10.1063/1.1681018
-
P.G. de Gennes, J. Chem. Phys. 60, 5030 (1974). JCPSA6 0021-9606 10.1063/1.1681018
-
(1974)
J. Chem. Phys.
, vol.60
, pp. 5030
-
-
De Gennes, P.G.1
-
33
-
-
84922809860
-
-
PRLTAO 0031-9007 10.1103/PhysRevLett.114.068303
-
H. Kang, P.A. Pincus, C. Hyeon, and D. Thirumalai, Phys. Rev. Lett. 114, 068303 (2015). PRLTAO 0031-9007 10.1103/PhysRevLett.114.068303
-
(2015)
Phys. Rev. Lett.
, vol.114
, pp. 068303
-
-
Kang, H.1
Pincus, P.A.2
Hyeon, C.3
Thirumalai, D.4
-
34
-
-
84930237375
-
-
In Ref. [17] they use PEG-20000, not PEG-8000 as in the present study.
-
In Ref. [17] they use PEG-20000, not PEG-8000 as in the present study.
-
-
-
-
35
-
-
0030762777
-
-
JACSAT 0002-7863 10.1021/ja970445w
-
K. Yoshikawa, Y. Yoshikawa, Y. Koyama, and T. Kanbe, J. Am. Chem. Soc. 119, 6473 (1997). JACSAT 0002-7863 10.1021/ja970445w
-
(1997)
J. Am. Chem. Soc.
, vol.119
, pp. 6473
-
-
Yoshikawa, K.1
Yoshikawa, Y.2
Koyama, Y.3
Kanbe, T.4
-
36
-
-
0035864288
-
-
EMVRAE 0042-6822 10.1006/viro.2000.0735
-
N.H. Olson, M. Gingery, F.A. Eiserling, and T.S. Baker, Virology 279, 385 (2001). EMVRAE 0042-6822 10.1006/viro.2000.0735
-
(2001)
Virology
, vol.279
, pp. 385
-
-
Olson, N.H.1
Gingery, M.2
Eiserling, F.A.3
Baker, T.S.4
-
37
-
-
84999379721
-
-
In bulk the dominant state of DNA in the presence of condensing agents is rodlike or globular, but it can enter a toroidal state if the addition of condensing agents is carefully tuned. The toroidal state is also observed in single-molecule experiments with optical tweezers. For details, see Ref. [38] and references therein. A recent study with optical tweezers shows that PEG might also induce a toroidal state [39].
-
In bulk the dominant state of DNA in the presence of condensing agents is rodlike or globular, but it can enter a toroidal state if the addition of condensing agents is carefully tuned. The toroidal state is also observed in single-molecule experiments with optical tweezers. For details, see Ref. [38] and references therein. A recent study with optical tweezers shows that PEG might also induce a toroidal state [39].
-
-
-
-
38
-
-
77952258778
-
-
BIOJAU 0006-3495 10.1016/j.bpj.2009.12.4334
-
B. van den Broek, M.C. Noom, J. van Mameren, C. Battle, F.C. MacKintosh, and G.J.L. Wuite, Biophys. J. 98, 1902 (2010). BIOJAU 0006-3495 10.1016/j.bpj.2009.12.4334
-
(2010)
Biophys. J.
, vol.98
, pp. 1902
-
-
Van Den Broek, B.1
Noom, M.C.2
Van Mameren, J.3
Battle, C.4
Mackintosh, F.C.5
Wuite, G.J.L.6
-
39
-
-
84896064432
-
-
EBJOE8 0175-7571 10.1007/s00249-013-0941-x
-
H. Ojala, G. Ziedaite, A.E. Wallin, D.H. Bamford, and E. Hæggström, Eur. Biophys. J. 43, 71 (2014). EBJOE8 0175-7571 10.1007/s00249-013-0941-x
-
(2014)
Eur. Biophys. J.
, vol.43
, pp. 71
-
-
Ojala, H.1
Ziedaite, G.2
Wallin, A.E.3
Bamford, D.H.4
Hæggström, E.5
-
40
-
-
52649084912
-
-
LCAHAM 1473-0197 10.1039/b805614e
-
K.J. Morton, K. Loutherback, D.W. Inglis, O.K. Tsui, J.C. Sturm, S.Y. Chou, and R.H. Austin, Lab Chip 8, 1448 (2008). LCAHAM 1473-0197 10.1039/b805614e
-
(2008)
Lab Chip
, vol.8
, pp. 1448
-
-
Morton, K.J.1
Loutherback, K.2
Inglis, D.W.3
Tsui, O.K.4
Sturm, J.C.5
Chou, S.Y.6
Austin, R.H.7
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