Ibogan, tacaman, and cytotoxic bisindole alkaloids from Tabernaemontana. Cononusine, an iboga alkaloid with unusual incorporation of a pyrrolidone moiety

Journal of Natural Products

Volumn 78, Issue 5, 2015, Pages 1129-1138

  Lim, Kuan Hon ^a   Raja, Vijay J ^b   Bradshaw, Tracey D ^b   Lim, Siew Huah ^c   Low, Yun Yee ^c   Kam, Toh Seok ^c  

^a UNIVERSITY OF NOTTINGHAM MALAYSIA CAMPUS   (Malaysia)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^c UNIVERSITY OF MALAYA   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

16 DECARBOMETHOXYVOACAMINE; 16 DECARBOMETHOXYVOACAMINEPSEUDOINDOXYL; 2 PYRROLIDONE DERIVATIVE; 6 OXOIBOGAINE; CONONUSINE; CYTOTOXIC AGENT; ERVALUTEINE; ERVATENSINE A; ERVATENSINE B; IBOGAINE; INDOLE ALKALOID; N 4 CHLOROMETHYLNORFLUOROCURARINE CHLORIDE; PLANT EXTRACT; TABERNAEMONTANA CORYMBOSA EXTRACT; TACAMONIDINE; UNCLASSIFIED DRUG; VINCAMAJICINE; VINCRISTINE; ANTINEOPLASTIC AGENT; INDOLE DERIVATIVE; TACAMAN;

ANISOTROPY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BARK; CANCER INHIBITION; CANCER RESISTANCE; CARBON NUCLEAR MAGNETIC RESONANCE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG DETERMINATION; DRUG ISOLATION; DRUG POTENCY; DRUG STRUCTURE; HETERONUCLEAR MULTIPLE QUANTUM COHERENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; MULTIDRUG RESISTANCE; NUCLEAR OVERHAUSER EFFECT; PROTON NUCLEAR MAGNETIC RESONANCE; TABERNAEMONTANA; TABERNAEMONTANA CORYMBOSA; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION; CELL CYCLE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; HCT116 CELL LINE; HT 29 CELL LINE; ISOLATION AND PURIFICATION; KB CELL LINE; MALAYSIA;

TABERNAEMONTANA; TABERNAEMONTANA CORYMBOSA;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE; DRUG RESISTANCE, MULTIPLE; DRUG SCREENING ASSAYS, ANTITUMOR; HCT116 CELLS; HT29 CELLS; HUMANS; INDOLE ALKALOIDS; INDOLES; KB CELLS; MALAYSIA; MOLECULAR STRUCTURE; PYRROLIDINONES; TABERNAEMONTANA; VINCRISTINE;

EID: 84930226302     PISSN: 01633864     EISSN: 15206025     Source Type: Journal    
DOI: 10.1021/acs.jnatprod.5b00117     Document Type: Article

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