The prognostic factors and multiple biomarkers in young patients with colorectal cancer

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Wang, Mo Jin ^a,b   Ping, Jie ^b   Li, Yuan ^a   Adell, Gunnar ^b   Arbman, Gunnar ^b   Nodin, Bjorn ^c   Meng, Wen Jian ^a,b   Zhang, Hong ^d   Yu, Yong Yang ^a   Wang, Cun ^a   Yang, Lie ^a   Zhou, Zong Guang ^a   Sun, Xiao Feng ^a,b  

^a SICHUAN UNIVERSITY   (China)

^b LINKÖPING UNIVERSITY   (Sweden)

^c LUND UNIVERSITY   (Sweden)

^d ÖREBRO UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

PROLACTIN; PROTEIN P53; RBM3 PROTEIN, HUMAN; RNA BINDING PROTEIN; TELOMERASE; TELOMERASE CAJAL BODY PROTEIN 1, HUMAN; TUMOR MARKER;

ADULT; AGE; AGED; CANCER STAGING; COLORECTAL NEOPLASMS; DEMOGRAPHY; DISEASE FREE SURVIVAL; FACTUAL DATABASE; FEMALE; GENETICS; HUMAN; INCIDENCE; KAPLAN MEIER METHOD; MALE; METABOLISM; MIDDLE AGED; MORTALITY; PATHOLOGY; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; PROTEIN PROTEIN INTERACTION;

ADULT; AGE FACTORS; AGED; BIOMARKERS, TUMOR; COLORECTAL NEOPLASMS; DATABASES, FACTUAL; DEMOGRAPHY; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; INCIDENCE; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; NEOPLASM STAGING; PROGNOSIS; PROLACTIN; PROPORTIONAL HAZARDS MODELS; PROTEIN INTERACTION MAPS; RNA-BINDING PROTEINS; TELOMERASE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84930225151     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep10645     Document Type: Article

References (44)

1. Garcia, M. et al. Global Cancer Facts & Figures 2007. Atlanta, GA: American Cancer Society (2007), www.cancer.org/acs/groups/ content/@nho/documents/document/globalfactsandfigures 2007rev2p.pdf. [accessed March 1, 2015].
2. Edwards, B. K. et al. Annual report to the nation on the status of cancer, 1975-2006, featuring colorectal cancer trends and impact of interventions (risk factors, screening, and treatment) to reduce future rates. Cancer 116, 544-573 (2010).
3. Siegel, R., Naishadham, D. & Jemal, A. Cancer statistics, 2013. CA Cancer J Clin 63, 11-30 (2013).
4. Allemani, C. et al. Global surveillance of cancer survival 1995-2009: analysis of individual data for 25 676 887 patients from 279 population-based registries in 67 countries (CONCORD-2). Lancet 385, 977-1010 (2015).
5. Sung, J. J., Lau, J. Y., Goh, K. L., Leung, W. K. & Asia Pacific Working Group on Colorectal, C. Increasing incidence of colorectal cancer in Asia: implications for screening. Lancet Oncol 6, 871-876 (2005).
6. Siegel, R. L., Jemal, A. & Ward, E. M. Increase in incidence of colorectal cancer among young men and women in the United States. Cancer Epidemiol Biomarkers Prev 18, 1695-1698 (2009).
7. Bacon, H. E. & Sealy, W. B. Malignancy of the anus, rectum and sigmoid colon in the young: With report of a case at four and a half years. Am J Surg 45, 9 (1939).
8. O'Connell, J. B., Maggard, M. A., Livingston, E. H. & Yo, C. K. Colorectal cancer in the young. Am J Surg 187, 343-348 (2004).
9. You, Y. N., Xing, Y., Feig, B. W., Chang, G. J. & Cormier, J. N. Young-onset colorectal cancer: is it time to pay attention? Arch Intern Med 172, 287-289 (2012).
10. Davis, D. M. et al. Is it time to lower the recommended screening age for colorectal cancer? J Am Coll Surg 213, 352-361 (2011).
11. Cicek, M. S. et al. Colorectal cancer linkage on chromosomes 4q21, 8q13, 12q24, and 15q22. PLoS One 7, e38175 (2012).
12. Kirzin, S. et al. Sporadic early-onset colorectal cancer is a specific sub-type of cancer: a morphological, molecular and genetics study. PLoS One 9, e103159 (2014).
13. Marble, K., Banerjee, S. & Greenwald, L. Colorectal carcinoma in young patients. J Surg Oncol 51, 179-182 (1992).
14. Boland, C. R. & Goel, A. Microsatellite instability in colorectal cancer. Gastroenterology 138, 2073-2087, e2073 (2010).
15. Liang, J. T. et al. Clinicopathological and molecular biological features of colorectal cancer in patients less than 40 years of age. Br J Surg 90, 205-214 (2003).
16. Yantiss, R. K. et al. Clinical, pathologic, and molecular features of early-onset colorectal carcinoma. Am J Surg Pathol 33, 572-582 (2009).
17. Wallin, A. R., Svanvik, J., Adell, G. & Sun, X. F. Expression of PRL proteins at invasive margin of rectal cancers in relation to preoperative radiotherapy. Int J Radiat Oncol Biol Phys 65, 452-458 (2006).
18. Hjelm, B. et al. High nuclear RBM3 expression is associated with an improved prognosis in colorectal cancer. Proteomics Clin Appl 5, 624-635 (2011).
19. Zhang, H., Wang, D. W., Adell, G. & Sun, X. F. WRAP53 is an independent prognostic factor in rectal cancer- a study of Swedish clinical trial of preoperative radiotherapy in rectal cancer patients. BMC Cancer 12, 294 (2012).
20. Sun, X. F. et al. Prognostic significance of cytoplasmic p53 oncoprotein in colorectal adenocarcinoma. Lancet 340, 1369-1373 (1992).
21. Torsello, A. et al. P53 and bcl-2 in colorectal cancer arising in patients under 40 years of age: distribution and prognostic relevance. Eur J Cancer 44, 1217-1222 (2008).
22. Krajcovic, M. & Overholtzer, M. Mechanisms of ploidy increase in human cancers: a new role for cell cannibalism. Cancer Res 72, 1596-1601 (2012).
23. Sun, X. F. Clinicopathological and biological features of DNA tetraploid colorectal cancers. Cancer J 12, 501-506 (2006).
24. Slattery, M. L., Lundgreen, A., Kadlubar, S. A., Bondurant, K. L. & Wolff, R. K. JAK/STAT/SOCS-signaling pathway and colon and rectal cancer. Mol Carcinog 52, 155-166 (2013).
25. Knutsen, A., Adell, G. & Sun, X. F. Inflammatory infiltration, fibrosis, necrosis and mucinous content in relation to clinicopathological and molecular factors in rectal cancers with or without preoperative radiotherapy. Oncol Rep 16, 321-327 (2006).
26. Gnosa, S. et al. AEG-1 expression is an independent prognostic factor in rectal cancer patients with preoperative radiotherapy: a study in a Swedish clinical trial. Br J Cancer 111, 166-173 (2014).
27. Shabo, I., Olsson, H., Sun, X. F. & Svanvik, J. Expression of the macrophage antigen CD163 in rectal cancer cells is associated with early local recurrence and reduced survival time. Int J Cancer 125, 1826-1831 (2009).
28. Sun, X. F., Carstensen, J. M. & Nordenskjold, B. Expression of c-erbB-2 and p53 in colorectal adenocarcinoma. Anal Cell Pathol 8, 203-211 (1995).
29. Zhang, H. & Sun, X. F. Overexpression of cyclooxygenase-2 correlates with advanced stages of colorectal cancer. Am J Gastroenterol 97, 1037-1041 (2002).
30. Gao, J. et al. Clinical and biological significance of angiogenesis and lymphangiogenesis in colorectal cancer. Dig Liver Dis 41, 116-122 (2009).
31. Loftas, P. et al. Expression of FXYD-3 is an independent prognostic factor in rectal cancer patients with preoperative radiotherapy. Int J Radiat Oncol Biol Phys 75, 137-142 (2009).
32. Jansson, A. & Sun, X. F. Ki-67 expression in relation to clinicopathological variables and prognosis in colorectal adenocarcinomas. APMIS 105, 730-734 (1997).
33. Moparthi, S. B. et al. Expression of MAC30 protein is related to survival and biological variables in primary and metastatic colorectal cancers. Int J Oncol 30, 91-95 (2007).
34. Evertsson, S. & Sun, X. F. Protein expression of NF-kappaB in human colorectal adenocarcinoma. Int J Mol Med 10, 547-550 (2002).
35. Sun, X. F. p73 overexpression is a prognostic factor in patients with colorectal adenocarcinoma. Clin Cancer Res 8, 165-170 (2002).
36. Loof, J. et al. Impact of PINCH expression on survival in colorectal cancer patients. BMC Cancer 11, 103, doi:10.1186/1471-2407-11-103 (2011).
37. Yang, L. et al. Biological function and prognostic significance of peroxisome proliferator-activated receptor delta in rectal cancer. Clin Cancer Res 17, 3760-3770 (2011).
38. Sun, X. F., Ekberg, H., Zhang, H., Carstensen, J. M. & Nordenskjold, B. Overexpression of ras is an independent prognostic factor in colorectal adenocarcinoma. APMIS 106, 657-664 (1998).
39. Pathak, S. et al. Tafazzin protein expression is associated with tumorigenesis and radiation response in rectal cancer: a study of Swedish clinical trial on preoperative radiotherapy. PLoS One 9, e98317 (2014).
40. Evertson, S. et al. Microsatellite instability and MBD4 mutation in unselected colorectal cancer. Anticancer Res 23, 3569-3574 (2003).
41. Adell, G. C. et al. Apoptosis in rectal carcinoma: prognosis and recurrence after preoperative radiotherapy. Cancer 91, 1870-1875 (2001).
42. Franceschini, A. et al. STRING v9.1: protein-protein interaction networks, with increased coverage and integration. Nucleic Acids Res 41, D808-815 (2013).
43. Wang, J., Duncan, D., Shi, Z. & Zhang, B. WEB-based GEne SeT AnaLysis Toolkit (WebGestalt): update 2013. Nucleic Acids Res 41, W77-83 (2013).
44. Kanehisa, M. & Goto, S. KEGG: kyoto encyclopedia of genes and genomes. Nucleic Acids Res 28, 27-30 (2000).