메뉴 건너뛰기




Volumn 5, Issue 5, 2015, Pages

Biomarkers of necrotising soft tissue infections: Aspects of the innate immune response and effects of hyperbaric oxygenation-the protocol of the prospective cohort BIONEC study

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; BIOLOGICAL MARKER; C REACTIVE PROTEIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; FICOLIN; IMMUNOGLOBULIN; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 6; N(G),N(G) DIMETHYLARGININE; NITRITE; PENTRAXIN 3; PROCALCITONIN; REACTIVE OXYGEN METABOLITE; IL6 PROTEIN, HUMAN; SERUM AMYLOID P;

EID: 84930216570     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2014-006995     Document Type: Article
Times cited : (11)

References (46)
  • 3
    • 34247323981 scopus 로고    scopus 로고
    • Mortality in patients with necrotizing fasciitis
    • Golger A, Ching S, Goldsmith CH, et al. Mortality in patients with necrotizing fasciitis. Plast Reconstr Surg 2007; 119: 1803-7.
    • (2007) Plast Reconstr Surg , vol.119 , pp. 1803-1807
    • Golger, A.1    Ching, S.2    Goldsmith, C.H.3
  • 4
    • 0034953739 scopus 로고    scopus 로고
    • Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patients
    • Muller B, Peri G, Doni A, et al. Circulating levels of the long pentraxin PTX3 correlate with severity of infection in critically ill patients. Crit Care Med 2001; 29: 1404-7.
    • (2001) Crit Care Med , vol.29 , pp. 1404-1407
    • Muller, B.1    Peri, G.2    Doni, A.3
  • 5
    • 4043184173 scopus 로고    scopus 로고
    • Selective induction of pentraxin 3, a soluble innate immune pattern recognition receptor, in infectious episodes in patients with haematological malignancy
    • Al-Ramadi BK, Ellis M, Pasqualini F, et al. Selective induction of pentraxin 3, a soluble innate immune pattern recognition receptor, in infectious episodes in patients with haematological malignancy. Clin Immunol Orlando Fla 2004; 112: 221-4.
    • (2004) Clin Immunol Orlando Fla , vol.112 , pp. 221-224
    • Al-Ramadi, B.K.1    Ellis, M.2    Pasqualini, F.3
  • 6
    • 58849092264 scopus 로고    scopus 로고
    • Pentraxin 3 and C-reactive protein in severe meningococcal disease
    • Sprong T, Peri G, Neeleman C, et al. Pentraxin 3 and C-reactive protein in severe meningococcal disease. Shock Augusta Ga 2009; 31: 28-32.
    • (2009) Shock Augusta Ga , vol.31 , pp. 28-32
    • Sprong, T.1    Peri, G.2    Neeleman, C.3
  • 7
    • 77951204731 scopus 로고    scopus 로고
    • Persisting high levels of plasma pentraxin 3 over the first days after severe sepsis and septic shock onset are associated with mortality
    • Mauri T, Bellani G, Patroniti N, et al. Persisting high levels of plasma pentraxin 3 over the first days after severe sepsis and septic shock onset are associated with mortality. Intensive Care Med 2010; 36: 621-9.
    • (2010) Intensive Care Med , vol.36 , pp. 621-629
    • Mauri, T.1    Bellani, G.2    Patroniti, N.3
  • 8
    • 79952516148 scopus 로고    scopus 로고
    • High plasma level of long pentraxin 3 (PTX3) is associated with fatal disease in bacteremic patients: A prospective cohort study
    • Huttunen R, Hurme M, Aittoniemi J, et al. High plasma level of long pentraxin 3 (PTX3) is associated with fatal disease in bacteremic patients: a prospective cohort study. PLoS ONE 2011; 6:e17653.
    • (2011) PLoS ONE , vol.6 , pp. e17653
    • Huttunen, R.1    Hurme, M.2    Aittoniemi, J.3
  • 9
    • 84872343230 scopus 로고    scopus 로고
    • Pentraxin 3 (PTX3) is associated with severe sepsis and fatal disease in emergency room patients with suspected infection: A prospective cohort study
    • Uusitalo-Seppälä R, Huttunen R, Aittoniemi J, et al. Pentraxin 3 (PTX3) is associated with severe sepsis and fatal disease in emergency room patients with suspected infection: a prospective cohort study. PLoS ONE 2013; 8:e53661.
    • (2013) PLoS ONE , vol.8 , pp. e53661
    • Uusitalo-Seppälä, R.1    Huttunen, R.2    Aittoniemi, J.3
  • 10
    • 84883634419 scopus 로고    scopus 로고
    • Pentraxin-3 serum levels are associated with disease severity and mortality in patients with systemic inflammatory response syndrome
    • Bastrup-Birk S, Skjoedt MO, Munthe-Fog L, et al. Pentraxin-3 serum levels are associated with disease severity and mortality in patients with systemic inflammatory response syndrome. PLoS ONE 2013; 8: e73119.
    • (2013) PLoS ONE , vol.8 , pp. e73119
    • Bastrup-Birk, S.1    Skjoedt, M.O.2    Munthe-Fog, L.3
  • 11
    • 29944445392 scopus 로고    scopus 로고
    • Serum C-reactive protein as a marker of outcome and infection in critical care patients
    • Seller-Pérez G, Herrera-Gutiérrez ME, Lebrón-Gallardo M, et al. [Serum C-reactive protein as a marker of outcome and infection in critical care patients]. Med Clínica 2005; 125: 761-5.
    • (2005) Med Clínica , vol.125 , pp. 761-765
    • Seller-Pérez, G.1    Herrera-Gutiérrez, M.E.2    Lebrón-Gallardo, M.3
  • 12
    • 3242810355 scopus 로고    scopus 로고
    • Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: A systematic review and meta-analysis
    • Simon L, Gauvin F, Amre DK, et al. Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis. Clin Infect Dis Off Publ Infect Dis Soc Am 2004; 39: 206-17.
    • (2004) Clin Infect Dis off Publ Infect Dis Soc Am , vol.39 , pp. 206-217
    • Simon, L.1    Gauvin, F.2    Amre, D.K.3
  • 13
    • 33745622134 scopus 로고    scopus 로고
    • Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: A systematic review and meta-analysis
    • Uzzan B, Cohen R, Nicolas P, et al. Procalcitonin as a diagnostic test for sepsis in critically ill adults and after surgery or trauma: a systematic review and meta-analysis. Crit Care Med 2006; 34: 1996-2003.
    • (2006) Crit Care Med , vol.34 , pp. 1996-2003
    • Uzzan, B.1    Cohen, R.2    Nicolas, P.3
  • 14
    • 79953001345 scopus 로고    scopus 로고
    • Biomarkers in the critically ill patient: Procalcitonin
    • Reinhart K, Meisner M. Biomarkers in the critically ill patient: procalcitonin. Crit Care Clin 2011; 27: 253-63.
    • (2011) Crit Care Clin , vol.27 , pp. 253-263
    • Reinhart, K.1    Meisner, M.2
  • 15
    • 44049107587 scopus 로고    scopus 로고
    • Serum IL-1beta, IL-6, IL-8, and TNF-alpha levels in early diagnosis and management of neonatal sepsis
    • Kurt ANC, Aygun AD, Godekmerdan A, et al. Serum IL-1beta, IL-6, IL-8, and TNF-alpha levels in early diagnosis and management of neonatal sepsis. Mediators Inflamm 2007; 2007: 31397.
    • (2007) Mediators Inflamm , vol.2007 , pp. 31397
    • Kurt, A.N.C.1    Aygun, A.D.2    Godekmerdan, A.3
  • 16
    • 8544262221 scopus 로고    scopus 로고
    • Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab')2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels
    • Panacek EA, Marshall JC, Albertson TE, et al. Efficacy and safety of the monoclonal anti-tumor necrosis factor antibody F(ab')2 fragment afelimomab in patients with severe sepsis and elevated interleukin-6 levels. Crit Care Med 2004; 32: 2173-82.
    • (2004) Crit Care Med , vol.32 , pp. 2173-2182
    • Panacek, E.A.1    Marshall, J.C.2    Albertson, T.E.3
  • 17
    • 33747368257 scopus 로고    scopus 로고
    • Evaluation of serum C-reactive protein, procalcitonin, tumor necrosis factor alpha, and interleukin-10 levels as diagnostic and prognostic parameters in patients with community-acquired sepsis, severe sepsis, and septic shock
    • Heper Y, Akalin EH, Mistik R, et al. Evaluation of serum C-reactive protein, procalcitonin, tumor necrosis factor alpha, and interleukin-10 levels as diagnostic and prognostic parameters in patients with community-acquired sepsis, severe sepsis, and septic shock. Eur J Clin Microbiol Infect Dis Off Publ Eur Soc Clin Microbiol 2006; 25: 481-91.
    • (2006) Eur J Clin Microbiol Infect Dis off Publ Eur Soc Clin Microbiol , vol.25 , pp. 481-491
    • Heper, Y.1    Akalin, E.H.2    Mistik, R.3
  • 18
    • 33645961300 scopus 로고    scopus 로고
    • A new model for outcome prediction in intra-abdominal sepsis by the linear discriminant function analysis of IL-6 and IL-10 at different heart rates
    • Wang CH, Gee MJ, Yang C, et al. A new model for outcome prediction in intra-abdominal sepsis by the linear discriminant function analysis of IL-6 and IL-10 at different heart rates. J Surg Res 2006; 132: 46-51.
    • (2006) J Surg Res , vol.132 , pp. 46-51
    • Wang, C.H.1    Gee, M.J.2    Yang, C.3
  • 19
    • 0025266645 scopus 로고
    • Prognostic values of tumor necrosis factor/cachectin, interleukin-1, interferon-alpha, and interferon-gamma in the serum of patients with septic shock swiss-dutch j5 immunoglobulin study group
    • Calandra T, Baumgartner JD, Grau GE, et al. Prognostic values of tumor necrosis factor/cachectin, interleukin-1, interferon-alpha, and interferon-gamma in the serum of patients with septic shock. Swiss-Dutch J5 Immunoglobulin Study Group. J Infect Dis 1990; 161: 982-7.
    • (1990) J Infect Dis , vol.161 , pp. 982-987
    • Calandra, T.1    Baumgartner, J.D.2    Grau, G.E.3
  • 20
    • 0029998575 scopus 로고    scopus 로고
    • High tumor necrosis factor serum level is associated with increased survival in patients with abdominal septic shock: A prospective study in 59 patients
    • Riché F, Panis Y, Laisné MJ, et al. High tumor necrosis factor serum level is associated with increased survival in patients with abdominal septic shock: a prospective study in 59 patients. Surgery 1996; 120: 801-7.
    • (1996) Surgery , vol.120 , pp. 801-807
    • Riché, F.1    Panis, Y.2    Laisné, M.J.3
  • 21
    • 2942512827 scopus 로고    scopus 로고
    • Interleukin 13 and inflammatory markers in human sepsis
    • Collighan N, Giannoudis PV, Kourgeraki O, et al. Interleukin 13 and inflammatory markers in human sepsis. Br J Surg 2004; 91: 762-8.
    • (2004) Br J Surg , vol.91 , pp. 762-768
    • Collighan, N.1    Giannoudis, P.V.2    Kourgeraki, O.3
  • 22
    • 0028826247 scopus 로고
    • Clinical and biological significance of interleukin-10 plasma levels in patients with septic shock
    • Marchant A, Alegre ML, Hakim A, et al. Clinical and biological significance of interleukin-10 plasma levels in patients with septic shock. J Clin Immunol 1995; 15: 266-73.
    • (1995) J Clin Immunol , vol.15 , pp. 266-273
    • Marchant, A.1    Alegre, M.L.2    Hakim, A.3
  • 23
    • 34247623669 scopus 로고    scopus 로고
    • The diagnostic value of C-reactive protein, interleukin-8, and monocyte chemotactic protein in risk stratification of febrile neutropenic children with hematologic malignancies
    • El-Maghraby SM, Moneer MM, Ismail MM, et al. The diagnostic value of C-reactive protein, interleukin-8, and monocyte chemotactic protein in risk stratification of febrile neutropenic children with hematologic malignancies. J Pediatr Hematol Oncol 2007; 29: 131-6.
    • (2007) J Pediatr Hematol Oncol , vol.29 , pp. 131-136
    • El-Maghraby, S.M.1    Moneer, M.M.2    Ismail, M.M.3
  • 24
    • 0029839260 scopus 로고    scopus 로고
    • Serum MIP-1 alpha and IL-8 in septic patients
    • Fujishima S, Sasaki J, Shinozawa Y, et al. Serum MIP-1 alpha and IL-8 in septic patients. Intensive Care Med 1996; 22: 1169-75.
    • (1996) Intensive Care Med , vol.22 , pp. 1169-1175
    • Fujishima, S.1    Sasaki, J.2    Shinozawa, Y.3
  • 25
    • 0028129179 scopus 로고
    • Interleukin 6 is a prognostic indicator of outcome in severe intra-abdominal sepsis
    • Patel RT, Deen KI, Youngs D, et al. Interleukin 6 is a prognostic indicator of outcome in severe intra-abdominal sepsis. Br J Surg 1994; 81: 1306-8.
    • (1994) Br J Surg , vol.81 , pp. 1306-1308
    • Patel, R.T.1    Deen, K.I.2    Youngs, D.3
  • 26
    • 0035421655 scopus 로고    scopus 로고
    • Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis
    • Harbarth S, Holeckova K, Froidevaux C, et al. Diagnostic value of procalcitonin, interleukin-6, and interleukin-8 in critically ill patients admitted with suspected sepsis. Am J Respir Crit Care Med 2001; 164: 396-402.
    • (2001) Am J Respir Crit Care Med , vol.164 , pp. 396-402
    • Harbarth, S.1    Holeckova, K.2    Froidevaux, C.3
  • 27
    • 17444450470 scopus 로고    scopus 로고
    • Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations: Comparisons in patients with septic shock, cardiogenic shock, and bacterial pneumonia
    • De Werra I, Jaccard C, Corradin SB, et al. Cytokines, nitrite/nitrate, soluble tumor necrosis factor receptors, and procalcitonin concentrations: comparisons in patients with septic shock, cardiogenic shock, and bacterial pneumonia. Crit Care Med 1997; 25: 607-13.
    • (1997) Crit Care Med , vol.25 , pp. 607-613
    • De Werra, I.1    Jaccard, C.2    Corradin, S.B.3
  • 28
    • 80052221610 scopus 로고    scopus 로고
    • The role of endogenous H2S in cardiovascular physiology
    • Skovgaard N, Gouliaev A, Aalling M, et al. The role of endogenous H2S in cardiovascular physiology. Curr Pharm Biotechnol 2011; 12: 1385-93.
    • (2011) Curr Pharm Biotechnol , vol.12 , pp. 1385-1393
    • Skovgaard, N.1    Gouliaev, A.2    Aalling, M.3
  • 29
    • 33644843003 scopus 로고    scopus 로고
    • Hydrogen sulphide-A novel mediator of inflammation?
    • Li L, Bhatia M, Moore PK. Hydrogen sulphide-a novel mediator of inflammation? Curr Opin Pharmacol 2006; 6: 125-9.
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 125-129
    • Li, L.1    Bhatia, M.2    Moore, P.K.3
  • 30
    • 21744443081 scopus 로고    scopus 로고
    • Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse
    • Li L, Bhatia M, Zhu YZ, et al. Hydrogen sulfide is a novel mediator of lipopolysaccharide-induced inflammation in the mouse. FASEB J Off Publ Fed Am Soc Exp Biol 2005; 19: 1196-8.
    • (2005) FASEB J off Publ Fed Am Soc Exp Biol , vol.19 , pp. 1196-1198
    • Li, L.1    Bhatia, M.2    Zhu, Y.Z.3
  • 31
    • 12844279008 scopus 로고    scopus 로고
    • Hyperbaric oxygen protects against lipopolysaccharide-stimulated oxidative stress and mortality in rats
    • Lin HC, Wan FJ, Wu CC, et al. Hyperbaric oxygen protects against lipopolysaccharide-stimulated oxidative stress and mortality in rats. Eur J Pharmacol 2005; 508: 249-54.
    • (2005) Eur J Pharmacol , vol.508 , pp. 249-254
    • Lin, H.C.1    Wan, F.J.2    Wu, C.C.3
  • 32
    • 61449096475 scopus 로고    scopus 로고
    • Hyperbaric oxygen causes both antiinflammation and antipyresis in rabbits
    • Niu KC, Huang WT, Lin MT, et al. Hyperbaric oxygen causes both antiinflammation and antipyresis in rabbits. Eur J Pharmacol 2009; 606: 240-5.
    • (2009) Eur J Pharmacol , vol.606 , pp. 240-245
    • Niu, K.C.1    Huang, W.T.2    Lin, M.T.3
  • 33
    • 58649110201 scopus 로고    scopus 로고
    • Hyperbaric oxygen reduces inflammatory response in acute pancreatitis by inhibiting NF-kappaB activation
    • Yu X, Li YG, He XW, et al. Hyperbaric oxygen reduces inflammatory response in acute pancreatitis by inhibiting NF-kappaB activation. Eur Surg Res Eur Chir Forsch Rech Chir Eur 2009; 42: 130-5.
    • (2009) Eur Surg Res Eur Chir Forsch Rech Chir Eur , vol.42 , pp. 130-135
    • Yu, X.1    Li, Y.G.2    He, X.W.3
  • 34
    • 0034040890 scopus 로고    scopus 로고
    • Hyperbaric oxygen treatment attenuates cytokine induction after massive hemorrhage
    • Yamashita M, Yamashita M. Hyperbaric oxygen treatment attenuates cytokine induction after massive hemorrhage. Am J Physiol Endocrinol Metab 2000; 278: E811-16.
    • (2000) Am J Physiol Endocrinol Metab , vol.278 , pp. E811-E816
    • Yamashita, M.1    Yamashita, M.2
  • 35
    • 0034014259 scopus 로고    scopus 로고
    • Hyperbaric oxygen downregulates ICAM-1 expression induced by hypoxia and hypoglycemia: The role of NOS
    • Buras JA, Stahl GL, Svoboda KK, et al. Hyperbaric oxygen downregulates ICAM-1 expression induced by hypoxia and hypoglycemia: the role of NOS. Am J Physiol Cell Physiol 2000; 278: C292-302.
    • (2000) Am J Physiol Cell Physiol , vol.278 , pp. C292-302
    • Buras, J.A.1    Stahl, G.L.2    Svoboda, K.K.3
  • 36
    • 33748776288 scopus 로고    scopus 로고
    • Hyperbaric oxygen protects from sepsis mortality via an interleukin-10-dependent mechanism
    • Buras JA, Holt D, Orlow D, et al. Hyperbaric oxygen protects from sepsis mortality via an interleukin-10-dependent mechanism. Crit Care Med 2006; 34: 2624-9.
    • (2006) Crit Care Med , vol.34 , pp. 2624-2629
    • Buras, J.A.1    Holt, D.2    Orlow, D.3
  • 37
    • 0037251861 scopus 로고    scopus 로고
    • Methodologies for the sensitive and specific measurement of S-nitrosothiols, iron-nitrosyls, and nitrite in biological samples
    • Yang BK, Vivas EX, Reiter CD, et al. Methodologies for the sensitive and specific measurement of S-nitrosothiols, iron-nitrosyls, and nitrite in biological samples. Free Radic Res 2003; 37: 1-10.
    • (2003) Free Radic Res , vol.37 , pp. 1-10
    • Yang, B.K.1    Vivas, E.X.2    Reiter, C.D.3
  • 38
    • 84880934609 scopus 로고    scopus 로고
    • A NO way to BOLD? Dietary nitrate alters the hemodynamic response to visual stimulation
    • Aamand R, Dalsgaard T, Ho YCL, et al. A NO way to BOLD? Dietary nitrate alters the hemodynamic response to visual stimulation. NeuroImage 2013; 83: 397-407.
    • (2013) NeuroImage , vol.83 , pp. 397-407
    • Aamand, R.1    Dalsgaard, T.2    Ho, Y.C.L.3
  • 39
    • 0026710191 scopus 로고
    • Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis the accp/sccm consensus conference committee american college of chest physicians/society of critical care medicine
    • Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 1992; 101: 1644-55.
    • (1992) Chest , vol.101 , pp. 1644-1655
    • Bone, R.C.1    Balk, R.A.2    Cerra, F.B.3
  • 40
    • 0037389094 scopus 로고    scopus 로고
    • 2001 Sccm/esicm/accp/ats/sis international sepsis definitions conference
    • Levy MM, Fink MP, Marshall JC, et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Crit Care Med 2003; 31: 1250-6.
    • (2003) Crit Care Med , vol.31 , pp. 1250-1256
    • Levy, M.M.1    Fink, M.P.2    Marshall, J.C.3
  • 41
    • 84901314494 scopus 로고    scopus 로고
    • Cytokine and nitric oxide levels in patients with sepsis-temporal evolvement and relation to platelet mitochondrial respiratory function
    • Sjövall F, Morota S, Asander Frostner E, et al. Cytokine and nitric oxide levels in patients with sepsis-temporal evolvement and relation to platelet mitochondrial respiratory function. PLoS ONE 2014; 9:e97673.
    • (2014) PLoS ONE , vol.9 , pp. e97673
    • Sjövall, F.1    Morota, S.2    Asander Frostner, E.3
  • 42
    • 84875111847 scopus 로고    scopus 로고
    • Nitric oxide and its metabolites in the critical phase of illness: Rapid biomarkers in the making
    • Mian AI, Aranke M, Bryan NS. Nitric oxide and its metabolites in the critical phase of illness: rapid biomarkers in the making. Open Biochem J 2013; 7: 24-32.
    • (2013) Open Biochem J , vol.7 , pp. 24-32
    • Mian, A.I.1    Aranke, M.2    Bryan, N.S.3
  • 43
    • 23744467412 scopus 로고    scopus 로고
    • Differential inducible nitric oxide synthase activity in circulating neutrophils vs. Mononuclears of septic shock patients
    • Hersch M, Scott JA, Izbicki G, et al. Differential inducible nitric oxide synthase activity in circulating neutrophils vs. mononuclears of septic shock patients. Intensive Care Med 2005; 31: 1132-5.
    • (2005) Intensive Care Med , vol.31 , pp. 1132-1135
    • Hersch, M.1    Scott, J.A.2    Izbicki, G.3
  • 44
    • 24944479871 scopus 로고    scopus 로고
    • Neutrophils, nitric oxide, and microvascular permeability in severe sepsis
    • Dhillon SS, Mahadevan K, Bandi V, et al. Neutrophils, nitric oxide, and microvascular permeability in severe sepsis. Chest 2005; 128: 1706-12.
    • (2005) Chest , vol.128 , pp. 1706-1712
    • Dhillon, S.S.1    Mahadevan, K.2    Bandi, V.3
  • 45
    • 0038790425 scopus 로고    scopus 로고
    • Relationships of circulating nitrite/nitrate levels to severity and multiple organ dysfunction syndrome in systemic inflammatory response syndrome
    • Mitaka C, Hirata Y, Yokoyama K, et al. Relationships of circulating nitrite/nitrate levels to severity and multiple organ dysfunction syndrome in systemic inflammatory response syndrome. Shock Augusta Ga 2003; 19: 305-9.
    • (2003) Shock Augusta Ga , vol.19 , pp. 305-309
    • Mitaka, C.1    Hirata, Y.2    Yokoyama, K.3
  • 46
    • 0033839194 scopus 로고    scopus 로고
    • Nitric oxide indices in human septic shock
    • Strand OA, Leone A, Giercksky KE, et al. Nitric oxide indices in human septic shock. Crit Care Med 2000; 28: 2779-85.
    • (2000) Crit Care Med , vol.28 , pp. 2779-2785
    • Strand, O.A.1    Leone, A.2    Giercksky, K.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.