Cyparissins A and B, jatrophane diterpenes from Euphorbia cyparissias as Pgp inhibitors and cytotoxic agents against ovarian cancer cell lines

Fitoterapia

Volumn 104, Issue , 2015, Pages 75-79

  Lanzotti, Virginia ^a   Barile, Elisa ^b   Scambia, Giovanni ^c   Ferlini, Cristiano ^d  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b BURNHAM INSTITUTE   (United States)

^c CATHOLIC UNIVERSITY   (Italy)

^d DANBURY HOSPITAL   (United States)

Author keywords

A2780 WT and ADR; Cyparissin; Cytotoxic activity; Euphorbia cyparissias L; Jatrophane diterpenes; P gp inhibition

Indexed keywords

CYPARISSIN A; CYPARISSIN B; DITERPENE; MULTIDRUG RESISTANCE PROTEIN; PLANT EXTRACT; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; JATROPHANE;

ARTICLE; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; EUPHORBIA; EUPHORBIA CYPARISSIAS; HUMAN; HUMAN CELL; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OVARIAN CANCER CELL LINE; PRIORITY JOURNAL; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; DRUG RESISTANCE; FEMALE; METABOLISM; MULTIDRUG RESISTANCE; OVARY TUMOR; PATHOLOGY; TUMOR CELL LINE;

EUPHORBIA CYPARISSIAS;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE, TUMOR; DITERPENES; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; EUPHORBIA; FEMALE; HUMANS; MOLECULAR STRUCTURE; OVARIAN NEOPLASMS; P-GLYCOPROTEIN;

EID: 84930208359     PISSN: 0367326X     EISSN: 18736971     Source Type: Journal    
DOI: 10.1016/j.fitote.2015.05.012     Document Type: Article

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