Rating Apathy in Huntington's Disease: Patients and Companions Agree

Journal of Huntington's Disease

Volumn 4, Issue 1, 2015, Pages 49-59

  Mason, Sarah ^a   Barker, Roger A ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

apathy; cognition; companion; depression; Huntington's disease; longitudinal; self rated

Indexed keywords

ADULT; APATHY; ARTICLE; CAG REPEAT; CLINICAL FEATURE; COGNITION; COMPARATIVE STUDY; DEPRESSION; FEMALE; FRONTAL LOBE; FUNCTIONAL ASSESSMENT; FUNCTIONAL DISEASE; FUNCTIONAL STATUS; HUMAN; HUNTINGTON CHOREA; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PATTERN RECOGNITION; PRIORITY JOURNAL; SELF REPORT; AGED; COHORT ANALYSIS; CROSS-SECTIONAL STUDY; DISEASE COURSE; FRIEND; HUNTINGTON DISEASE; LONGITUDINAL STUDY; PROSPECTIVE STUDY; PSYCHOLOGY; REPRODUCIBILITY;

DOPAMINE RECEPTOR BLOCKING AGENT;

ADULT; AGED; APATHY; COHORT STUDIES; CROSS-SECTIONAL STUDIES; DEPRESSION; DISEASE PROGRESSION; DOPAMINE ANTAGONISTS; FEMALE; FRIENDS; HUMANS; HUNTINGTON DISEASE; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; SELF REPORT;

EID: 84930188744     PISSN: 18796397     EISSN: 18796400     Source Type: Journal    
DOI: 10.3233/JHD-140133     Document Type: Article

References (46)

1. Bates G, Harper P, Jones L. Huntington's disease. 3rd. Oxford: New York Oxford University Press (UK); 2002.
2. van Duijn E, Kingma EM, van der Mast RC. Psychopathology in verified Huntington's disease gene carriers. J Neuropsychiatry Clin Neurosci. 2007;19:441-8.
3. Schoenfeld M, Myers RH, Cupples LA, Berkman B, Sax DS, Clark E. Increased rate of suicide among patients with Huntington's disease. J Neurol Neurosurg Psychiatry. 1984;47:1283-7.
4. Fiedorowicz JG, Mills JA, Ruggle A, Langbehn D, Paulsen JS, Group P-HIotHS. Suicidal behavior in prodromal Huntington disease. Neurodegener Dis. 2011;8:483-90.
5. Zappacosta B, Monza D, Meoni C, Austoni L, Soliveri P, Gellera C, Alberti R, Mantero M, Penati G, Caraceni T, Girotti F. Psychiatric symptoms do not correlate with cognitive decline, motor symptoms, or CAG repeat length in Huntington's disease. Arch Neurol. 1996;53:493-97.
6. Svenaeus F. Diagnosing mental disorders and saving the normal: American Psychiatric Association, 2013. Diagnostic and statistical manual of mental disorders, 5th ed. American Psychiatric Publishing: Washington, DC. 991 pp., Med Health Care Philos. 2013.
7. Paulsen JS, Ready RE, Hamilton JM, Mega MS, Cummings JL. Neuropsychiatric aspects of Huntington's disease. J Neurol Neurosurg Psychiatry. 2001;71:310-4.
8. Thompson JC, Harris J, Sollom AC, Stopford CL, Howard E, Snowden JS, Craufurd D. Longitudinal evaluation of neuropsychiatric symptoms in Huntington's disease. J Neuropsychiatry Clin Neurosci. 2012;24:53-60.
9. Naarding P, Janzing JG, Eling P, van der Werf S, Kremer B. Apathy is not depression in Huntington's disease. J Neuropsychiatry Clin Neurosci. 2009;21:266-70.
10. Tabrizi SJ, Scahill RI, Owen G, Durr A, Leavitt BR, Roos RA, Borowsky B, Landwehrmeyer B, Frost C, Johnson H, Craufurd D, Reilmann R, Stout JC, Langbehn DR. Predictors of phenotypic progression and disease onset in premanifest and early-stage Huntington's disease in the TRACK-HD study: Analysis of 36-month observational data. Lancet Neurol. 2013;12:637-49.
11. Levy ML, Cummings JL, Fairbanks LA, Masterman D, Miller BL, Craig AH, Paulsen JS, Litvan I. Apathy is not depression. J Neuropsychiatry Clin Neurosci. 1998;10:314-9.
12. Craufurd D, Thompson JC, Snowden JS. Behavioral changes in Huntington Disease. Neuropsychiatry Neuropsychol Behav Neurol. 2001;14:219-26.
13. Thompson JC, Snowden JS, Craufurd D, Neary D. Behavior in Huntington's disease: Dissociating cognition-based and mood-based changes. J Neuropsychiatry Clin Neurosci. 2002;14:37-43.
14. Kingma EM, van Duijn E, Timman R, van der Mast RC, Roos RA. Behavioural problems in Huntington's disease using the Problem Behaviours Assessment. Gen Hosp Psychiatry. 2008;30:155-61.
15. Baudic S, Maison P, Dolbeau G, Boisse MF, Bartolomeo P, Dalla Barba G, Traykov L, Bachoud-Levi AC. Cognitive impairment related to apathy in early Huntington's disease. Dement Geriatr Cogn Disord. 2006;21:316-21.
16. Hamilton JM, Salmon DP, Corey-Bloom J, Gamst A, Paulsen JS, Jerkins S, Jacobson MW, Peavy G. Behavioural abnormalities contribute to functional decline in Huntington's disease. J Neurol Neurosurg Psychiatry. 2003;74:120-2.
17. Banaszkiewicz K, Sitek EJ, Rudzinska M, Soltan W, Slawek J, Szczudlik A. Huntington's disease from the patient, caregiver and physician's perspectives: Three sides of the same coin? J Neural Transm. 2012;119:1361-5.
18. van Duijn E, Reedeker N, Giltay EJ, Roos RA, van der Mast RC. Correlates of apathy in Huntington's disease. J Neuropsychiatry Clin Neurosci. 2010;22:287-94.
19. Huntington Study Group. Unified Huntington's Disease Rating Scale: Reliability and consistency. Huntington Study Group. Mov Disord. 1996;11:136-42.
20. Marin RS. Apathy: A neuropsychiatric syndrome. J Neuropsychiatry Clin Neurosci. 1991;3:243-54.
21. Read J, Jones R, Owen G, Leavitt BR, Coleman A, Roos RA, Dumas EM, Durr A, Justo D, Say M, Stout JC, Tabrizi SJ, Craufurd D, investigators T-H. Quality of life in Huntington's disease: A comparative study investigating the impact for those with pre-manifest and early manifest disease, and their partners. J Huntingtons Dis. 2013;2: 159-75.
22. Sitek EJ, Soltan W, Robowski P, Schinwelski M, Wieczorek D, Slawek J. Poor insight into memory impairment in patients with Huntington disease. Neurol Neurochir Pol. 2012;46:318-25.
23. Ho AK, Robbins AO, Barker RA. Huntington's disease patients have selective problems with insight. Mov Disord. 2006;21:385-9.
24. Justo D, Charles P, Daunizeau J, Delmaire C, Gargiulo M, Hahn-Barma V, Naccache L, Durr A. Is non-recognition of choreic movements in Huntington disease always pathological? Neuropsychologia. 2013;51:748-59.
25. Chatterjee A, Anderson KE, Moskowitz CB, Hauser WA, Marder KS. A comparison of self-report and caregiver assessment of depression, apathy, and irritability in Huntington's disease. J Neuropsychiatry Clin Neurosci. 2005;17:378-83.
26. Marin RS, Biedrzycki RC, Firinciogullari S. Reliability and validity of the Apathy Evaluation Scale. Psychiatry Res. 1991;38:143-62.
27. Glenn MB, Burke DT, O'Neil-Pirozzi T, Goldstein R, Jacob L, Kettell J. Cutoff score on the apathy evaluation scale in subjects with traumatic brain injury. Brain Inj. 2002;16: 509-16.
28. Kirsch-Darrow L, Fernandez HH, Marsiske M, Okun MS, Bowers D. Dissociating apathy and depression in Parkinson disease. Neurology. 2006;67:33-8.
29. Marin RS, Firinciogullari S, Biedrzycki RC. Group differences in the relationship between apathy and depression. J Nerv Ment Dis. 1994;182:235-9.
30. Begeti F, Tan AY, Cummins GA, Collins LM, Guzman NV, Mason SL, Barker RA. The Addenbrooke's Cognitive Examination-Revised accurately detects cognitive decline in Huntington's disease. J Neurol. 2013;260:2777-85.
31. Folstein MF, Folstein SE, McHugh PR. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12:189-98.
32. Coslett HB, Bowers D, Verfaellie M, Heilman KM. Frontal verbal amnesia. Phonological amnesia. Arch Neurol. 1991;48:949-55.
33. Crowe SF. Dissociation of two frontal lobe syndromes by a test of verbal fluency. J Clin Exp Neuropsychol. 1992;14:327-39.
34. Corcoran R, Upton D. A role for the hippocampus in card sorting? Cortex. 1993;29:293-304.
35. Cuenod CA, Bookheimer SY, Hertz-Pannier L, Zeffiro TA, Theodore WH, Le Bihan D. Functional MRI during word generation, using conventional equipment:Apotential tool for language localization in the clinical environment. Neurology. 1995;45:1821-27.
36. Martin RC, Loring DW, Meador KJ, Lee GP. The effects of lateralized temporal lobe dysfunction on formal and semantic word fluency. Neuropsychologia. 1990;28:823-29.
37. Robbins TW, James M, Owen AM, Sahakian BJ, McInnes L, Rabbitt P. Cambridge Neuropsychological Test Automated Battery (CANTAB): A factor analytic study of a large sample of normal elderly volunteers. Dementia. 1994;5:266-81.
38. Owen AM, Sahakian BJ, Semple J, Polkey CE, Robbins TW. Visuo-spatial short-term recognition memory and learning after temporal lobe excisions, frontal lobe excisions or amygdalo-hippocampectomy in man. Neuropsychologia. 1995;33:1-24.
39. Rogers RD, Sahakian BJ, Hodges JR, Polkey CE, Kennard C, Robbins TW. Dissociating executive mechanisms of task control following frontal lobe damage and Parkinson's disease. Brain. 1998;121 (Pt 5):815-42.
40. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry. 1961;4:561-71.
41. Richter P, Werner J, Heerlein A, Kraus A, Sauer H. On the validity of the Beck Depression Inventory. A review. Psychopathology. 1998;31:160-8.
42. Lane-Brown AT, Tate RL. Measuring apathy after traumatic brain injury: Psychometric properties of the Apathy Evaluation Scale and the Frontal Systems Behavior Scale. Brain Inj. 2009;23:999-1007.
43. van Duijn E, Reedeker N, Giltay EJ, Eindhoven D, Roos RA, van der Mast RC. Course of irritability, depression and apathy in Huntington's disease in relation to motor symptoms during a two-year follow-up period. Neurodegener Dis. 2014;13: 9-16.
44. Solomon AC, Stout JC, Weaver M, Queller S, Tomusk A, Whitlock KB, Hui SL, Marshall J, Jackson JG, Siemers ER, Beristain X, Wojcieszek J, Foroud T. Ten-year rate of longitudinal change in neurocognitive and motor function in prediagnosis Huntington disease. Mov Disord. 2008;23:1830-6.
45. Brandt J, Bylsma FW, Gross R, Stine OC, Ranen N, Ross CA. Trinucleotide repeat length and clinical progression in Huntington's disease. Neurology. 1996;46:527-31.
46. Mason SL, Wijeyekoon R, Swain R, Ho AK, Smith EL, Sahakian B, Barker RA. Cognitive followup of a small cohort of Huntington's disease patients over a 5 year period. PLoS Curr. 2010;2:RRN1174.